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Publikacije (48383)

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H. Tahirović, Jelena Simić

The aim of the article is to present to the medical, and then to the general public, the person and work of Milivoje Sarvan (1896–1978)—one of the pioneers of social paediatrics in Serbia and one of the most prominent paediatricians, scientists and organizers of health services in Bosnia and Herzegovina in the second half of the 20th century. Milivoje Sarvan was born in 1896 in Požega, in the Kingdom of Serbia. He completed his medical studies in Lyon (France) in 1921. Upon his return to Serbia, he was a county physician in Aleksinac for three years and, shortly after the establishment of the University Children’s Hospital in Belgrade in 1924, he was among the first assistants employed there. Out of the total of 23 years of professional work in Serbia, for 19 years he was an assistant and assistant professor at the Faculty of Medicine in Belgrade. At the end of 1946, at the initiative of the Ministry of Public Health of the People’s Republic of Bosnia and Herzegovina, Dr. Milivoje Sarvan was appointed full professor and head of the Department of Paediatrics at the newly established Faculty of Medicine in Sarajevo. At the same time, he was elected head of the Paediatric Clinic in Sarajevo when it was established, and he would later manage it from 1947 until his retirement in 1967. Already at the beginning, Prof. Sarvan developed the activities of the Clinic in several directions: he created the conditions for clinical, teaching and scientific research work. He took care of the education of future paediatricians and child care workers, organized courses in social paediatrics for general practitioners and professional training for paediatricians in the country and abroad. The next period of his activities was marked by the intensive development of the Clinic in all areas of its work. He published more than 120 professional and scientific papers in national and foreign medical journals, and several health education books on mother and child care that have been published in several editions, with large print runs. He was the dean of the Faculty of Medicine and vice-rector of the University of Sarajevo, founder of the Paediatric Section of the Society of Physicians of Bosnia and Herzegovina, lifetime president of the Association of Paediatricians of Yugoslavia, a member of the Scientific Society of Bosnia and Herzegovina from 1955 and the Academy of Sciences and Arts of Bosnia and Herzegovina from its foundation in 1966. He was honoured with high level social awards and recognitions, including the highest state award of the Socialist Federative Republic of Yugoslavia—the AVNOJ award. After his retirement (1967), he lived in Belgrade, where he died in 1978. Conclusion. Bearing all of this in mind, there is no doubt that Dr. Milivoje Sarvan is one of the significant figures in the field of professional, scientific and organizational work in the field of children’s health care in the former Yugoslavia, leaving a significant and indelible mark in the current states of Serbia and Bosnia and Herzegovina.

J. Kamberović, M. Gligora Udovič, Antonija Kulaš, K. Tapolczai, S. Orlić, Amela Jusufović, Almina Gajić, P. Žutinić et al.

Tufa deposits in karst rivers are unique habitats created by mutual interactions between specific environmental and biotope features and inhabited by diatoms as a highly abundant and diverse algal group. This pilot study aimed to investigate the diversity of diatom communities on tufa depositing habitats and assess the Una River’s ecological status using a comparative molecular and morphological approach for diatom identification. The 312 base pairs of the rbcL gene were barcoded and analyzed using MiSeq reads and amplicon sequence variants (ASVs) obtained by the DADA2 pipeline. The reference database Diat.barcode v7 was used for taxonomic assignment. The morphological identification of the diatoms was carried out in parallel. In total, the combined dataset revealed 46 taxa identified at genus rank, 125 on the subgenus, and 145 on combined taxonomy rank. The metabarcoding approach mostly leads to a lower number of identified taxa at species rank (58 in molecular vs. 119 in optical inventory), resulting in higher values of beta diversity and heterogeneity in diatom assemblages in samples obtained by morphological approach. Despite the high percentage of taxonomically not assigned diatom ASVs to the species rank, high Shannon diversity index values and a similar number of taxa per locations compared to the morphological approach were obtained. Taxa Achnanthidium minutissimum (Kützing) Czarnecki, Achnanthidium pyrenaicum (Hustedt) H.Kobayasi, Amphora pediculus (Kützing) Grunow, Diatoma vulgaris Bory, Navicula cryptotenella Lange-Bertalot, and Navicula tripunctata (O.F.Müller) Bory were identified at all locations in both inventories. Although limited consistency in the diatom abundances between the two inventory datasets was found, a similar grouping of samples was observed connected to the river’s longitudinal gradient. The data obtained using molecular approach in most sites indicated a mostly lower ecological status (good or moderate) compared to the data obtained from the morphological approach (high, good, and moderate). The potential of environmental DNA (eDNA) diatom metabarcoding for water monitoring and diversity studies is undeniable, but to fully realize the benefits of these methods in the future, it is essential to standardize protocols and expand the reference database for species found in specific habitats, such as tufa deposits.

Manuel M. Ferreira, F. Cardoso, S. Ambroziak, Mariella Särestöniemi, Kenan Turbic, Luís M. Correia

In this article, an analysis of system loss and depolarization in body area networks (BANs) for body-to-infrastructure (B2I) communications based on a measurement campaign in the 5.8 GHz band in an indoor environment is performed. Measurements were performed with an off-body antenna transmitting linearly polarized signals and dual-polarized receiving antennas carried by the user on the body. A normal distribution with a mean of 2.0 dB and a standard deviation of 4.3 dB is found to be the best fit for modeling cross-polarization (XP) discrimination. The average correlation between the signals received by the orthogonally polarized antennas is below 0.5, showing that polarization diversity can be used. A model for the average value of the standard deviation of the XP discrimination ratio as a function of the transmitted polarization, the mobility of users, and the link dynamics is presented, together with a detailed description of the methodology being used.

Alejna Krilić, N. Hodzic, E. Bećirović

Abstract Global trends in food fortification, particularly in milk, and the increasing availability of fermented milk products have raised awareness of the link between nutrition and health, leading to higher consumption of these products. Consumers’ decisions to purchase fermented milk products are influenced by economic, psychological, cultural, and socio-demographic factors, along with preferences related to brand, price, taste, and nutritional value. This study aims to examine the impact of socio-demographic characteristics on production and marketing factors when purchasing fermented milk products, as well as on the choice of specific brands. The research was conducted using a survey method, with a questionnaire as the primary data collection tool. A total of 326 consumers participated in the survey. Data were analyzed using descriptive statistics, frequency distribution, analysis of variance, and the chi-square test. The results indicate that socio-demographic characteristics significantly influence production and marketing considerations, as well as brand choice when it comes to fermented milk products. However, the chi-square test showed no statistically significant relationship between sociodemographic characteristics and consumer attitudes toward fermented milk products. These findings can help producers and marketers better understand consumer behavior and tailor their strategies accordingly.

Alejna Krilić, Merjem Sinanović, Merima Makaš, Almir Toroman, V. Falan

Abstract Social media plays a crucial role in influencing consumer purchasing decisions, particularly in the context of food products. Platforms like Facebook, Instagram, and other social networks offer consumers easy access to a wealth of information, including reviews, recommendations, and insights from other users. As more consumers turn to online sources for information and shopping, it becomes essential for food companies to develop and execute digital marketing strategies that not only enhance product visibility but also foster consumer trust. The main objective of this study is to examine the impact of company activity on social media on consumers’ decisions to purchase food products. Additionally, the study aims to explore whether socio-demographic factors influence consumers’ attitudes toward food marketing on social media and how these factors affect the choice of social media platforms used to gather information about food products. To gather data, a survey was conducted, and the results were analyzed using descriptive statistics, frequency distribution, variance analysis, and regression techniques. Total of 156 respondents participating in the research. The findings revealed that company activity on social media significantly influences consumer purchasing decisions concerning food products. Furthermore, socio-demographic characteristics were found to affect the types of social media most commonly used by respondents for obtaining food-related information.

Milica Dragicevic-Antonic, L. Ranković-Ničić, Gordana Stamenkovic, Maša Petrović, Goran Loncar, N. Marković, Ana Dimitrijevic, Sulin Bulatović et al.

We present the case of a 49-year-old female of Caucasian European descent with chest tightness, fatigue, and palpitations, ultimately diagnosed with primary intracardiac angiosarcoma. Initial echocardiography revealed a significant mass within the right atrium, infiltrating the free wall. Surgical intervention included tumor excision and partial resection of the superior vena cava. Histopathological examination confirmed a high-grade angiosarcoma. Postoperative imaging identified a recurrent mass in the right atrium, suggestive of thrombus, alongside Takotsubo cardiomyopathy. Considering the elevated surgical risks and the presence of cardiomyopathy, management included anticoagulation therapy with Warfarin and adjuvant chemotherapy with Paclitaxel. Follow-up cardiac magnetic resonance imaging demonstrated a recurrent angiosarcoma with superimposed thrombus. This case presents the complex diagnostic and therapeutic landscape of angiosarcoma, highlighting the critical importance of early surgical intervention, advanced imaging techniques, and vigilant postoperative monitoring.

I. Burazor, M. Colic, Stefan Grujić, P. Otašević, Rade Babic, Milovan Bojic, V. Giga, Vladimir Kanjuh et al.

A. P. Plex Sulá, Valentina De Col, B. Etherton, Yanru Xing, Amogh Agarwal, Lejla Ramic, Enrico Bonaiuti, Michael L. Friedmann et al.

Bin James E Aidan P Rosie K Anu Rodrigo M Nayu Lakshya Zhou Bennett Wickham Singleton Mishra Carrillo-Lar, Bin James E Aidan P Rosie K Anu Rodrigo M Nayu Lakshya Zhou Bennett Wickham Singleton Mishra Carrillo-Lar, Bin Zhou, James E. Bennett, Aidan P. Wickham, Rosie K. Singleton, Anu Mishra, R. Carrillo-Larco et al.

BACKGROUND Adiposity can be measured using BMI (which is based on weight and height) as well as indices of abdominal adiposity. We examined the association between BMI and waist-to-height ratio (WHtR) within and across populations of different world regions and quantified how well these two metrics discriminate between people with and without hypertension. METHODS We used data from studies carried out from 1990 to 2023 on BMI, WHtR and hypertension in people aged 20-64 years in representative samples of the general population in eight world regions. We graphically compared the regional distributions of BMI and WHtR, and calculated Pearson's correlation coefficients between BMI and WHtR within each region. We used mixed-effects linear regression to estimate the extent to which WHtR varies across regions at the same BMI. We graphically examined the prevalence of hypertension and the distribution of people who have hypertension both in relation to BMI and WHtR, and we assessed how closely BMI and WHtR discriminate between participants with and without hypertension using C-statistic and net reclassification improvement (NRI). FINDINGS The correlation between BMI and WHtR ranged from 0·76 to 0·89 within different regions. After adjusting for age and BMI, mean WHtR was highest in south Asia for both sexes, followed by Latin America and the Caribbean and the region of central Asia, Middle East and north Africa. Mean WHtR was lowest in central and eastern Europe for both sexes, in the high-income western region for women, and in Oceania for men. Conversely, to achieve an equivalent WHtR, the BMI of the population of south Asia would need to be, on average, 2·79 kg/m2 (95% CI 2·31-3·28) lower for women and 1·28 kg/m2 (1·02-1·54) lower for men than in the high-income western region. In every region, hypertension prevalence increased with both BMI and WHtR. Models with either of these two adiposity metrics had virtually identical C-statistics and NRIs for every region and sex, with C-statistics ranging from 0·72 to 0·81 and NRIs ranging from 0·34 to 0·57 in different region and sex combinations. When both BMI and WHtR were used, performance improved only slightly compared with using either adiposity measure alone. INTERPRETATION BMI can distinguish young and middle-aged adults with higher versus lower amounts of abdominal adiposity with moderate-to-high accuracy, and both BMI and WHtR distinguish people with or without hypertension. However, at the same BMI level, people in south Asia, Latin America and the Caribbean, and the region of central Asia, Middle East and north Africa, have higher WHtR than in the other regions. FUNDING UK Medical Research Council and UK Research and Innovation (Innovate UK).

Johannes Deeg, Michael Swoboda, D. Egle, Verena Wieser, A. Soleiman, Valentin K. Ladenhauf, Malik Galijašević, Birgit Amort et al.

Background: A better understanding of the peritumoral stroma changes due to tumour invasion using non-invasive diagnostic methods may improve the differentiation between benign and malignant breast lesions. This study aimed to assess the correlation between breast lesion differentiation and intra- and peritumoral shear-wave elastography (SWE) gradients. Methods: A total of 135 patients with newly diagnosed breast lesions were included. Intratumoral, subsurface, and three consecutive peritumoral SWE value measurements (with three repetitions) were performed. Intratumoral, interface, and peritumoral gradients (Gradient 1 and Gradient 2) were calculated using averaged SWE values. Statistical analysis included descriptive statistics and an ordinary one-way ANOVA to compare overall and individual gradients among Breast Imaging-Reporting and Data System (BI-RADS) 2, 3, and 5 groups. Results: Malignant tumours showed higher average SWE velocity values at the tumour centre (BI-RADS 2/3: 4.1 ± 1.8 m/s vs. BI-RADS 5: 4.9 ± 2.0 m/s, p = 0.04) and the first peritumoral area (BI-RADS 2/3: 3.4 ± 1.8 m/s vs. BI-RADS 5: 4.3 ± 1.8 m/s, p = 0.003). No significant difference was found between intratumoral gradients (0.03 ± 0.32 m/s vs. 0.0 ± 0.28 m/s; p > 0.999) or gradients across the tumour–tissue interface (−0.17 ± 0.18 m/s vs. −0.13 ± 0.35 m/s; p = 0.202). However, the first peritumoral gradient (−0.16 ± 0.24 m/s vs. −0.35 ± 0.31 m/s; p < 0.0001) and the second peritumoral gradient (−0.11 ± 0.18 m/s vs. −0.22 ± 0.28 m/s; p = 0.037) were significantly steeper in malignant tumours. The AUC was best for PTG1 (0.7358) and PTG2 (0.7039). A threshold value for peritumoral SWI PT1 above 3.76 m/s and for PTG1 below −0.238 m/s·mm−1 indicated malignancy in 90.6% of cases. Conclusions: Evaluating the peritumoral SWE gradient may improve the diagnostic pre-test probability, as malignant tumours showed a significantly steeper curve of the elasticity values in the peritumoral stroma compared to the linear regression with a relatively flat curve of benign lesions.

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