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Amina Vukotić, Adna Mesihović, A. Semić, S. Karakaš, Madida Mulic

Background: Water is essential in air conditioning processes, where it is used for cooling or heating. Its longer retention in the tanks and pipes of air conditioning devices can lead to physical and chemical changes that favor the appearance and reproduction of Legionella spp. This pathogen causes diseases that arise from inhalation of contaminated aerosol. The research was conducted in the Federation of Bosnia and Herzegovina, Bosnia and Herzegovina during 2023-2024. and included 30 public facilities where 54 water samples were collected from air conditioning devices. Objective: The main goal of the research was to determine the presence of Legionella spp. in water from air conditioning devices, and to examine correlation of physical and chemical parameters (temperature, residual chlorine, ph value, iron, zinc and copper) with the pathogen presence. An additional goal of the research was to examine the relationship between the physical and chemical parameters of water. Methods: The research was conducted at the territory of the Federation of Bosnia and Herzegovina (FBiH), Bosnia and Herzegovina (BiH) in the period 2023-2024. The samples were analysed in an authorized laboratory in Sarajevo, using standard microbiological and chemical methods. The water of the air conditioning units was analysed for presence of L. spp., the detection of the bacteria and the determination of the relationship between the examined physical and chemical factors and the settlement of pathogens in the air conditioning units. Results: Legionella spp. was isolated in 7 (13%) of 54 analysed samples. A correlation between higher temperature, lower residual chlorine, and higher concentrations of iron and copper with the bacteria appearance was established. Among the analysed parameters, several significant mutually positive correlations were recorded. Out of a total of 54 analysed samples from air conditioning devices, L. spp. was isolated in seven. The results showed that there is a relation between higher temperature and lower concentration of residual chlorine, as well as higher concentrations of Fe and Cu, with the occurrence of L. spp. in air conditioning devices. No statistically significant association between the presence of bacteria and Zn concentration or water pH was confirmed. By analysing the mutual relations between the tested physical and chemical parameters, the relation of Fe with Zn and Cu, and Zn with Cu and Ph value was determined. The limitation of this study refers to the fact that during the testing the so-called dead pipes in the system was not detected nor present, nor was there a test for the presence of biofilm inside the installation. Conclusion: The results indicate the importance of regular monitoring of water parameters in air conditioning devices in order to reduce the risk of Legionella spp. colonization and to improve preventive measures in public health and air conditioning engineering.

D. Horozic, A. Durak-Nalbantić, M. Hujdur, Adin Belet, A. Redžepović, O. Jusić, Demir Bejtović, M. Jamaković et al.

Introduction. Over the past decades, there has been a significant improvement in the quality of percutaneous coronary interventions (PCI). The goal of this study is to assess patient related risk factors for the development of ST in patients treated with PCI. Results. According to the study, the percentage of patients with ST who had bare metal stents (BMS) was significantly higher (72.41%) than that of patients without ST (27.59%). Conclusion. Lower ejection fraction, presence of dyslipidemia and usage of BMS were identified as independent predictors of ST. Keywords: Stent Thrombosis, Risk Factors, Prognosis.

J. Rakić, Biljana Kilibarda, Miloš Maksimović

Body image is most often defined as an individual's subjective perception of their physical appearance, i.e., the mental image that an individual has of their own body dimensions, contours, figure, and feelings associated with these characteristics. Adolescence is a critical period in the development of body image, and numerous factors have an influence on its development and characteristics - gender, age, family, peers, body mass index, socio-cultural norms, media, and physical activity. Biological factors, primarily age at which changes related to puberty occur, are considered crucial for the development of body image. Body image in early adolescence is primarily influenced by parents, and peer influence increases with age. Adolescent girls want to be thinner, while boys want to have an athletic appearance. Body mass index is one of the most important factors influencing body image and satisfaction with weight and physical appearance, and different studies have shown association between obesity and negative body image. During the last decades, the influence of the internet, social media, and computer games on body image has been significantly higher than traditional media such as television, newspapers, and magazines. A number of different questionnaires and scales are used to assess different aspects of body image. One of the most comprehensive studies that addresses different aspects of adolescent health and includes body image assessment is the Health Behaviour in School-aged Children Study, HBSC. Given that body image (dis)satisfaction can change drastically during adolescence, it can also have a significant impact on mental health (ranging from depression to anxiety), as well as other health-related behaviours. Therefore, it is important to identify adolescents at risk who will adopt different eating behaviors to regulate their body weight, especially those who underestimate and overestimate their body weight, as well as those who are obese.

Aida Celikovic, Emina Nesimi, N. Mlaco-vrazalic, A. Mlačo

Introduction. Owing to its high incidence and significant impact on public health, breast cancer represents a major clinical and epidemiological challenge. This study aimed to describe the clinicopathological and immunohistochemical characteristics of newly diagnosed breast cancer cases in Sarajevo. Results. Among 10,547 breast examinations, 165 breast cancers were detected (1.5–1.6% annual incidence). Conclusion. This study highlights the heterogeneity of breast cancer and emphasizes the need for further research to refine diagnostics and treatment. Keywords: Breast cancer, Estrogen Receptors, Progesterone Receptors.

Alen Omanović, N. Babic, A. Mlačo

Introduction. Psychiatric disorders frequently co-occur with chronic somatic diseases, trauma, and family psychiatric history. Results. Affective disorders were most prevalent (67%), particularly among women and retirees. Conclusion. Psychiatric diagnoses are closely intertwined with demographic and social factors, trauma, family history, and somatic comorbidities. These findings highlight the need for integrated, multidisciplinary care. Keywords: Age, Comorbidity, Mental Disorders, Sex, Somatic Diseases.

Akademik Mirko Pejanović u svom višegodišnjem naučnoistraživačkom radu imao je u fokusu nekoliko naučnih polja. On je pratio, izučavao i tumačio politički pluralizam u Bosni i Hercegovini, evropske i euroatlantske integracije u kontekstu Dejtonskog mirovnog sporazuma, državnost BiH u XX i XXI stoljeću, biografije istaknutih ličnosti BiH, nastavno-pedagoški i mentorski rad pojedinih doktoranata na fakultetima širom BiH, a posebno lokalnu i regionalnu samoupravu. Sve naučne oblasti koje su mu bile u fokusu i o kojima je pisao međusobno su povezane i prožimaju jedna drugu, iako na prvi pogled djeluju raznovrsno. Sve ove oblasti čine koherentnu cjelinu unutar političkih i pravnih nauka i, što je veoma važno, fokusirane su na državotvornu dinamiku BiH. Akademik Mirko Pejanović je pristupao ovim temama interdisciplinarno, spajajući politologiju, sociologiju, historiju i pravo, te javnu upravu i regionalizaciju, kako bi dao potpunije i sveobuhvatnije odgovore na ključna pitanja opstanka i razvoja BiH. Posebno mu je značajan naučni i pedagoški rad vezan za lokalnu i regionalnu samoupravu, ostvaren istraživanjima, oblikovanjem i definisanjem ovih veoma važnih oblasti ljudskog života, te doprinoseći razvoju tih oblasti ljudskog djelovanja. Njegov rad je, između ostalog, imao pozitivne posljedice, jer su ideje, istraživanja i pažljiva zaključivanja bili iskazani njegovim brojnim nastupima na konferencijama, okruglim stolovima, predavanjima, kao i napisanim člancima i knjigama, te su imali uticaj i efekte pri donošenju brojnih propisa, ali i u profiliranju politika na državnom i drugim nivoima u BiH.

Selma Novalija Islambegović, Senita Selimović, Amina Alić

Economic entities in the global market, within the oil industry, have become aware that they must pay attention to the environment in their business operations. Environmental accounting enables them to track and analyze the necessary information concerning their effects on the environment. For many economic entities, monitoring the harmful impacts on the environment and environmental protection is not only a challenge to meet the requirements of regulatory bodies and supply chains, due to the reputation of business image and consumer pressure, but also due to the necessity of a business strategy that promotes corporate sustainable development. The subject of this research is the analysis of the state of environmental accounting in the oil sector, while respecting the framework of sustainable development faced by economic entities in this sector. The aim of the paper is to investigate how much attention is devoted to environmental accounting and sustainable development in the oil industry in Bosnia and Herzegovina, and to apply the regulations that govern environmental accounting, as well as to systematize the components of environmental accounting, objectives, and dimensions of sustainable development. It has been established that the implementation of environmental accounting is weak, but that in making business decisions, economic entities in the oil sector in Bosnia and Herzegovina rely on the effects of the economic and environmental dimensions of sustainable development.

S. Juricic, M. Tešić, M. Dobric, Srdjan Aleksandic, Ivana Jovanović, Jovana Starcevic, J. Klać, Z. Mehmedbegović et al.

Introduction/Objective. Introduction/Objective Following the failure of the single-wire technique in percutaneous coronary intervention (PCI) for chronic total occlusions (CTO), two principal anterograde escalation strategies are commonly employed: the parallel-wire technique and antegrade wire escalation (AWE). Despite their widespread use, comparative data on the procedural characteristics and long-term clinical outcomes of these strategies remain scarce. This study aims to compare the procedural parameters and long-term outcomes of the parallel-wire and AWE techniques after single-wire failure in CTO PCI. Methods. This retrospective, single-center study included patients who underwent successful CTO PCI between January 2018 and December 2023 using either the parallel-wire or AWE technique following single-wire failure. The primary endpoint was a composite of cardiac death, myocardial infarction, stroke, or target vessel revascularization (TVR). Secondary outcomes included procedure duration, fluoroscopy time, contrast volume, and total radiation dose. Median follow-up duration was 1222 days (IQR 580-1969 days). Results. Among 270 CTO PCI procedures, 112 (41.5%) required escalation: 90with AWE and 22 with the parallel-wire technique. Baseline clinical and angiographic characteristics were comparable. The primary composite outcome occurred in 14.4% of the parallel-wire group and 9.1% of the AWE group (p = 0.73). No significant differences were observed in individual clinical events. Procedure duration was longer (95.5 ? 43.6 vs. 77.0 ? 30.7 min; p = 0.064) and contrast volume higher (336.4 ? 113.3 vs. 271.6 ? 90.6 mL; p = 0.014) in the AWE group, with similar fluoroscopy time and radiation dose. No clinically or ?ngiographically significant complications occurred during the periprocedural period. Conclusion. Both AWE and parallel-wire techniques demonstrate comparable safety and efficacy following single-wire failure in CTO PCI. While procedural efficiency slightly favored the parallel-wire strategy, overall outcomes support either approach, pending further prospective validation.

Aleksandar Jovanović, M. Drobac, Ivana Tadić, Bojana B Vidović, D. Pavlović, R. Veličković-Radovanović, Marina Odalović, Ana Kundalić et al.

From patients' perspective, the use of antibiotics to treat urinary tract infections (UTIs) in Serbia is unexplored, and therefore the aim of this study is to examine antibiotic use among these patients. An online cross-sectional study using snowball sampling was conducted during the winter of 2020/21 using a validated Google Docs questionnaire. The study included 236 female patients with a mean age of 34.9 ± 14.2 years. Most of the patients perceived UTI symptoms as severe (62.3%) and disruptive for their daily routines (51.3%). The majority of the patients (77.1%) used antibiotics by doctors' prescriptions. Other patients used antibiotics on their own and their selection. Self-treatment with antibiotics was associated with perceived symptom severity (p=0.006) and residence (p=0.017). In total, 17 different antibiotics were reported as being used for UTI treatment and the most frequent were fluoroquinolones (30.3%), cephalosporins (21.2%), and sulfonamides (15.7%). The highest consistency with national and European guidelines in doctors' decisions on antibiotic therapy was observed for treating UTIs in pregnant women (80.0%). These findings emphasize the need for education of healthcare professionals and clinical practice improvement in making rational antibiotic prescribing decisions.

Duško Kostić, M. Perušić, S. Stopić, Dragana Kostić, J. Vuković, Nebojša Vasiljević, Radislav Filipović, Vladimir Damjanović

Tionite is a solid residue formed during the production of titanium dioxide through the chloride process. This material is acidic and contains a high concentration of titanium, which makes it a potential secondary resource for titanium recovery. Instead of being disposed of as hazardous waste, tionite can be processed to extract valuable metals, particularly titanium. In this study, the recovery of titanium from tionite was carried out using an autoclave leaching method under high-pressure oxygen conditions. The presence of oxygen under pressure promotes the formation of titanium oxysulfate, which enhances the dissolution of titanium into solution. This approach enables selective leaching of titanium while limiting the dissolution of other unwanted elements. The leaching experiments were designed to explore optimal conditions for efficient titanium recovery, including temperature, pressure, and leaching time. The main objective of this research is to present a viable route for the valorisation of tionite by turning a hazardous acidic waste into a valuable source of titanium. This process contributes to waste reduction in the titanium dioxide industry and supports more sustainable resource management.

Georgiev Milošević, Lea Neškov, Sonja Nikić, Valentina Marinković, Marina Odalović, Dušanka M. Krajnović

Customer satisfaction reflects the quality of pharmaceutical services and depends on various factors, such as the quality of services, pharmacists' skills and customer' demographic characteristics. Positive experiences strengthen customer trust and loyalty. Research into user satisfaction is an important tool for improving services. The aim of the work was the analysis of user satisfaction with pharmacy services in Serbia over the last twelve years. Annual reports on user satisfaction in pharmacies from 2013 to 2024 were analyzed. Based on key indicators, a report was prepared comparing satisfaction over the years, taking into account various factors and service quality. With the exception of 2020, public, private and health center pharmacies participated every year. The highest response rate was recorded in 2015. More than 60% of users visit a pharmacy more than five times a year, usually waiting less than five minutes. The highest level of satisfaction with the availability of medicines was recorded in 2021, while overall satisfaction with services peaked in 2022. User satisfaction has remained stable, indicating good availability and quality of pharmaceutical services. The results may contribute to further improvement in practice.

Georgiev Milošević, Lea Neškov, Sonja Nikić, Dragiša Obradović, Valentina Marinković, Marina Odalović, Dušanka M. Krajnović

The college years are critical to students' health as they face various challenges, including social influences and unhealthy lifestyles. Limited access to health services in residence halls increases the risk of unhealthy behaviours. The aim of this study was to investigate students' attitudes towards public health services for primary prevention in dormitories and to make suggestions for improvement. A cross-sectional study was conducted using a questionnaire among students living in halls of residence. The survey explored students' views on healthcare and the availability of preventive services for students living away from home. A total of 996 students participated (response rate 99.1%). Most were unemployed (83.9%). The most frequent preventive visits were to dentists (34.4% twice a year, 24.7% once a year), while 37.7% never visited a gynaecologist/urologist. The majority (68.6%) stated that a pharmacy was necessary in their dormitories. Basic health services include general practitioners (82.3%) and psychologists (21.4%). Attitudes towards health centres varied significantly by place of residence (p<0.001). Primary prevention should be improved by health centres with student-friendly opening hours and additional activities that promote access to healthcare and awareness of prevention.

Dragana Dimitrić, Stanojević Bogavac, Dušanka M. Krajnović, D. Lakić

Venous leg ulcers (VLUs) account for most lower extremity wounds. Wound management include cleansing, debridement, infection control and applying wound dressing. There exist various types of dressings which can maintain adequate moisture, offer protection, and support the reepithelization of VLUs. The aim of this study is to evaluate the cost-effectiveness of the antimicrobial wound dressing containing ionic silver (Aquacel® Ag+Extra™) in the treatment of VLUs compared to conventional gauze dressing in Serbia. The data regarding the effectiveness and frequency of dressings for both the Aquacel® Ag+Extra™ and conventional dressing were obtained from literature sources. Only direct costs were considered, and values were taken from the published price list of health services or procurement procedures. Sensitivity analyses were performed. The total cost per patient for Aquacel® Ag+Extra™ was 34,178.76 RSD, while the total cost for gauze was 82,800.90 RSD. Besides lower costs, antimicrobial wound dressing shows higher effectiveness than the gauze, implying that Aquacel® Ag+Extra™ is the dominant strategy. The sensitivity analysis supports the robustness of the results. The use of antimicrobial wound dressing containing ionic silver is the preferred option for the treatment of VLUs due to lower costs and the higher curing rate of the wounds.

S. Delibegović, E. Idrizović, M. Katica, Jasminka Mustedanagic, E. Čičkušić, A. Katica, Haris Kuralić

Background Biological mesh derived from porcine small intestinal submucosa (SIS) has a higher porosity and is more hydrophilic than tissue derived from bovine and cow dermal tissues. Therefore, we believe SIS mesh will lead to a milder inflammatory reaction than other, polypropylene and polypropylene-polydioxanone meshes, fewer adhesions, and less mesh shrinkage. Methods Ninety rats were divided randomly into three groups: in group 1, polypropylene mesh was implanted; in group 2, polypropylene-polydioxanone; and in group 3, the SIS mesh. The meshes were fixed intra-abdominally, in the upper part of the abdomen. Ten animals from each group were sacrificed on days 7, 28, and 60 after the implantation. Relaparotomy was performed, with a left paramedial incision and the adhesions formed were assessed according to the Surgical Membrane Study Group (SMSG) score, along with the percentage of shrinkage of the mesh, and any inflammation. Results There were no differences in terms of inflammatory reaction or the formation of adhesions between the meshes tested on the 7th day after implantation. However, the shrinkage of the SIS mesh was more expressed. On days 28 and 60, the SIS mesh caused less inflammatory reaction and formation of adhesions in relation to the other meshes tested. On day 60, there was no significant difference in the size of the meshes. Conclusion This study confirmed that, despite conflicting views on biological mesh, SIS mesh results in less inflammatory reaction, less adhesion formation, and a lesser degree of shrinkage, and can take its place in hernia repair.

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