Introduction: A person’s response and functioning under condition of stress and confl ict is fundamentally different from its usual behavior. Aim: To point out what type of attitude toward the management of healthcare institutions is worth developing as well as to determine which psychological dimensions of employed the best refl ect the efficacy of the management.Methods: The study included a sample of 52 subjects employed at the Clinical center at University of Sarajevo and 64 subjects employed in Healthcare clinic in Sarajevo Canton. Survey method and a method of a theoretical analysis were used in the data collection and processing.Results: The study concluded that there is no statistically significant gender difference in attitude about the value of talent development at managerial level as a factor in development of attitude toward communicationin healthcare. We find t-value of 2,213 for the Clinical center at University of Sarajevo and 2,210 for Healthcare clinic in Sarajevo Canton.Conclusion: No statistically significant results have been found for any of the factors considered in the study with respect to the gender differences.

Introduction: The aim of this study is to determine prevalence of oral diseases and oral surgical procedures at Department of Oral Surgery, Faculty of Dental Medicine, University in Sarajevo.Methods: The current study is retrospective analysis of oral surgical procedures performed from January 2011 to December 2012 at Department of Oral Surgery, Faculty of Dental Medicine, University in Sarajevo. The data were statistically analyzed by T-test of independent samples and using Chi-squared test. P value lower than 0,001 was considered to be statistically significant.Results: A total of 1299 patients were included in study. The age range is from 18 to 84 years, with mean age ± SD= 35±15 years. There were 42 different clinical diagnoses, and 13 diagnoses appeared in more than 1% of all patients. Impacted and semi-impacted teeth, periapical lesions and retained roots are the most frequent diagnoses and represent 68% of all diagnoses. Embedded and impacted teeth (35%) and diseases of pulp and periapical tissues (31%) are the most frequent diagnoses with respect of ICD-10. Impacted teeth is the most common diagnosis and removal of impacted third molars is the most common oral surgical procedure.Conclusion: Study points out variety of dentoalveolar patology and complexity of dental health care that often requires interdisciplinary approach in order to achieve optimal outcome for patient.

Introduction: Injury during peripheral nerve blocks is relatively uncommon, but potentially devastating complication. Recent studies emphasized that location of needle insertion in relationship to the fascicles may be the predominant factor that determines the risk for neurologic complications. However, it is wellestablished that concentration of local anesthetic is also associated with the risk for injury. In this study, we examined the effect of location of injection and concentration of Ropivacaine on risk for neurologic complications. Our hypothesis is that location of the injection is more prognostic for occurrence of nerve injury than the concentration of Ropivacaine.Methods: In experimental design of the study fi fty Wistar rats were used and sciatic nerves were randomized to receive: Ropivacaine or 0.9% NaCl, either intraneurally or perineurally. Pressure data during application was acquired by using a manometer and was analyzed using software package BioBench. Neurologic examination was performed thought the following seven days, there after the rats were sacrificed while sciatic nerves were extracted for histological examination.Results: Independently of tested solution intraneural injections in most of cases resulted with high injection pressure, followed by obvious neurologic defi cit and microscopic destruction of peripheral nerves. Also, low injection pressure, applied either in perineural or intraneural extrafascicular area, resulted with transitory neurologic defi cit and without destruction of the nerve normal histological structure.Conclusions: The main mechanism which leads to neurologic injury combined with peripheral nerve blockade is intrafascicular injection. Higher concentrations of Ropivacaine during intrafascicular applications magnify nerve injury.

Introduction : One of the most important priorities in therapy is pain control. Therefore, many different groups of drugs are being used for this purpose, primarily opioid analgesics and non-steroidal anti-inflammatory drugs (NSAIDs). Opioid analgesic tramadol, by binding to specific receptors, modulates the perception and response to painful stimuli and inhibits transmitting and further processing of pain impulses. Lornoxicam, which belongs to the oxicam class of NSAIDs, is a non-selective cyclooxygenase inhibitor with strong analgesic and anti-inflammatory effects, and better tolerance profile. Preliminary research, which requires further verification, suggests that lornoxicam may be a better alternative or adjunctive therapy to opioid analgesics in the treatment of moderate to severe pain. The aim of this study was to investigate antinociceptive effects of lornoxicam, as well as the combination of lornoxicam with tramadol. Methods : Analgesic effect of combination of lornoxicam and tramadol or lornoxicam applied alone was examined on female albino mice, using a hot plate method. Measurements were made 30, 60, 90 and 120 minutes after intraperitoneal and subcutaneous administration, in dose of 10 mg/kg. Results: Combination of lornoxicam and tramadol, applied intraperitoneally, increases the threshold of sensitivity to painful stimuli, which was not the case with subcutaneous administration. Conclusions: Lornoxicam significantly increases analgesic effect when applied intraperitoneally in combination with tramadol. On the other hand, lornoxicam in combination with tramadol, did not increase the threshold of sensitivity to painful stimuli with significant difference, after subcutaneous administration

The NPK nutrients uptake in the production of cauliflower (Brassica oleracea var. botrytis L.) irrigated with different water quality (fresh and saline water of 4 dS/m) has been analyzed in the experiment conducted in the greenhouse of Mediterranean Agronomic Institute of Bari. The highest nitrogen (N) consumption was observed 10 weeks after transplantation, while the highest consumption of phosphorus (P) and potassium (K) was recorded 12 and 8 weeks after transplantation, respectively. The highest concentration of N in vegetative part was obtained in cauliflower under saline water irrigation (3.5%), while in the fresh water treatment concentration of N was 3.2%. The phosphorus uptake was significantly affected under saline irrigation practice with respect to the fresh water being with total P uptake value corresponding to about 61% of the its uptake under the fresh water treatment. Irrigation with the salinity level of 4 dS/m resulted in significant increase in the accumulated salts in soil being with an electric conductivity (EC) value 17% greater than the one where fresh water was practiced. Evolution of chloride (Cl - ) and its average values during the whole cropping period indicate that Cl - behaved in a manner identical to the one characterizing the EC parameter. This proves that Cl - concentration in the soil can be taken as a measure

Tipicni proizvodi su jos iz predbiblijskog vremena smatrani kulturnim blagom naroda i država o cemu svjedoce nađeni zapisi na vise geografskih lokacija. Kao takvi su se stitili legalnim sredstvima adekvatnim vremenu i prostoru njihovog postojanja. Termin tipicnih proizvoda kao predmeta intelektualnog vlasnistva prvi put je uveden 1883. godine kada je potpisan prvi multilateralni sporazum-Pariska konvencija o zastiti geografskih oznaka. Od tada do danas potpisan je niz dokumenata kojim se regulise pravo raspolaganja i prometovanja tipicnim proizvodima. Sve aktuelne varijacije i podvarijacije nacina zastite geografskih oznaka mogu svrstati zemlje u tri grupe i to: (1) Zemlje koje stite geografske oznake posebnim zakonom tzv. sui generis sistemom, (2) Zemlje koje stite geografske oznake kao trgovacke marke, sertifikacijske marke, kolektivne marke, ili nekim drugim zakonskim sredstvom, (3) Zemlje koje formalno ne prepoznaju i ne stite geografske oznake.  Na globalnom nivou, 111 zemalja, ukljucujuci 27 zemalja EU, stiti oznake geografskog porijekla sui generis sistemom. 56 zemalja stiti geografske oznake putem trgovackih marki, sertifikacijskih marki, ili kolektivnih marki, gdje spadaju Australija, Kanada, Japan i SAD. Veliki broj zemalja pored sui generis sistema ima dodatnu opciju zastite geografskih oznaka kao trgovackih marki kao sto je slucaj Kine.

VEGF-A is the most potent angiogenic factor in tumour angiogenesis. Its effects are mediated via two receptors VEGFR-1 and VEGFR-2. Primary aim of our study was to examine the expression of VEGFR-1 in breast cancer and its correlation to VEGF expression, lymph node status, tumour size, histological grade, and hormone receptor status. To examine the VEGFR-1 and VEGF expressions in tumour and surrounding tissue of 51 breast cancer patients, and in healthy breast tissue of 30 benign breast diseases patients, we used three-step immunohistochemical staining. VEGFR-1 and VEGF expressions were significantly increased in breast cancer tumour in relation to surrounding tissue (P < 0.01), and the VEGF expression was significantly increased in lymph node positive breast cancer patients (P < 0.01). VEGFR-1 and VEGF expressions were significantly higher in breast cancer tumour compared with healthy breast tissue (P < 0.01). Significant correlation between VEGF and VEGFR-1 expressions was found (P < 0.05). No significant correlations between VEGF and VEGFR-1 expressions and tumour size, histological grade, and hormone receptor status were found. Increased expression of VEGFR-1 and VEGF in breast cancer tumour and significant correlation between these proteins suggest the possible role of VEGF/VEGFR-1 signalization in breast cancer development, although VEGFR-1 potential prognostic value was not confirmed.

We present a new approach to regularize the displacement field of the accelerated Demons registration algorithm. The accelerated Demons algorithm uses Gaussian smoothing to penalize oscillatory motion in the displacement fields during registration. This regularization approach is often applied and ensures a smooth deformation field. However, when registering images with discontinuities in their motion field such as from organs sliding along the chest wall, the assumption of a smooth deformation field is invalid. In this work, we propose using total variation based smoothing that is known to better retain the discontinuities in the deformation field. The proposed approach is a first step towards automatically recovering breathing induced organ motion with good accuracy.

Antiphosphospholipid syndrome (APS) secundary to systemic lupus erythematosus (SLE) can be recognised in children with arterial or venous thrombosis. Amaurosis due to thrombosis of central retinal vene is rarely presenting manifestation of SLE with secondary APS.

Systemic onset Juvenile Idiopathic Arthritis (SoJIA) is rare pediatric disease, it accounts for 10% of children with Juvenile Idiopathic Arthritis. The onset of disese can be vary nonspecific and may suggest bacterial or viral infection, malignancy or other rheumatic disease. It is highly characterised by its extra-articular systemic illness features and, in some ways, it resembles a fever of unknown origin. Diagnosis is mostly clinical by using ILAR criteria (International League of Associations for Rheumatology).

Catatonia is a rarely reviewed clinical feature of neuropsychiatric (NP) manifestation of pediatric systemic lupus erythematosus (pSLE). It is a state of neurogenic motor immobility, and behavioral abnormality manifested by stupor.