Ovaj rad obrađuje savremena kretanja komercijalnog bankarstva sučeljavajući faze deregulacije i globalnom hipotekarnom krizom pokrenute reregulacije te djelatnosti. U deregulatornim uslovima je došlo do zaoštravanja konkurentske pozicije banaka, na što su one reagovale povišenom: marketizacijom, odnosno globalizacijom, koncentracijom, sekjuritizacijom i konglomeratizacijom, te profitno orjentisanim menadžmentom rizika svoje aktivnosti. Kontrakcija njihove kamatne margine je tako bila neutralizovana redukcijom operativnih troškova i rezervi za gubitke, te povećanjem nekamatnog prihoda održavajući bankarsku profitabilnost. Recentna kriza je ukazala na potrebu čvršće regulacije ili reregulacije bankarskog sektora, sa svrhom umanjenja njegovog sistemskog rizika u čemu se ističe značaj strožijih međunarodnih standarda bankarskog kapitala i likvidnosti, te potreba adekvatnog tretmana sistemski značajnih banaka. Reregulacija treba da ojača kapitaliziranost i likvidnost, ublaži obim, koncentraciju, internacionaliziranost i poslovnu razuđenost, te poboljša nadzor bankarskog sektora implicirajući njegovu nižu, ali stabilniju rentabilnost. Na takvo dejstvo donesenog dijela ciljanih regulatornih mjera upućuje viša likvidnost, niža globalizacija, usporenija koncentracija i sekjuritizacija, te stabilizaciono orjentisana aktivnost menadžmenta rizikom današnjih banaka. Njihov rast i profitabilnost su oboreni.

1 Department of Anesthesiology and Pain Management, Stroger Hospital of Cook County, Chicago, Illinois, USA; 2 Department of Pharmacology, Toxicology and Clinical Pharmacology, University of Banja Luka, Banja Luka, Bosnia and Herzegovina; 3 Department of Periodontology and Oral Medicine, Institute of Dentistry, Banja Luka, Bosnia and Herzegovina; 4 Department for Certification, The Republic of Srpska Agency for Certification, Accreditation and Quality Improvement in Health Care, Banja Luka, Bosnia and Herzegovina; 5 Department of Endodontic, Institute of Dentistry, Banja Luka, Bosnia and Herzegovina

Postoperative pain is common complication after daily dental care. Non-steroidal anti-inflammatory drugs are among most widely prescribed analgesics for management of postoperative pain. The analgesic effect of a non-steroidal antiinflammatory drug (NSAID) is related to its ability to inhibit prostaglandin synthesis. Ibuprofen (2-proprionic acid derivate) was discovered in the 1960s as a representative of NSAIDs. It is a peripherally acting analgesic with a potent anti-inflammatory action. An extensive retrospective analysis of randomized clinical trials conducted over the last 40 years demonstrated that ibuprofen is effective in moderate to severe postoperative pain for different indications in dentistry. In comparison to other NSAIDs, ibuprofen is characterized by its efficiency, safety and good tolerance. The aim of this article was to present the most important pharmacological and therapeutic characteristics and side effects of ibuprofen used for postoperative pain treatment in dentistry.

Introduction: Sentinel lymph node biopsy is a standard staging procedure in patients with early breast cancer. Aim of the study is a validation procedure of sentinel lymph node biopsy (SLNB) in our institution and comparison between two mapping techniques isotope mapping and methylene blue dye for lymphatic mapping. Material and methods: The study comprised 75 women with breast cancer of clinical stage T1-2N0M0. We analyzed patients from June, 2010 to March, 2013. In 39 patients, (Group A) lymphatic mapping technique was performed by using the peritumoral injection of 37MBq activity isotope (99m Technetium NANOCIS),and in 36 patients (Group B) mapping technique was performed by using the periareolar injection of 2-4 ml blue dye (Methylene blue 1%). Axillary dissection was performed in both groups after SLNB. Results: Out of 75 patients, sentinel lymph node was identified in 68 (90.7%). Identification rate was similar between the groups 89.7% (Group A), 91.7% (Group B). Accuracy rate was 97% between the groups, that is, Group A 97.1% and Group B 96.9%. In relation to the Group A (90.6%), sensitivity rate was slightly higher in the Group B 91.6%,. False negative rate of SLNB was higher in the Group A (9.1%) in relation to the Group B (8.3%). The average number of sentinel nodes detected in both groups was 1.2. Conclusion: The results of the study confirmed and validated both methods of lymphatic mapping techniques in SLNB. There were no significant statistical differences (p>0.05) in accuracy, sensitivity and false negative rate between these two groups.