INTRODUCTION Cesarean section (Sectio Caesarea) is a surgical method for the completion of delivery. After various historical modifications of operative techniques, modern approach consists in the transverse dissection of the anterior wall of the uterus. The rate of vaginal birth after cesarean section was significantly reduced from year to year, and the rate of repeated cesarean section is increased during the past 10 years. Evaluation of scar thickness is done by ultrasound, but it is still debatable size of thick scar that would be guiding "cut-off value" for the completion of the delivery method. GOAL The aim was to examine the most accurate ultrasonic method for assessing thickness scar on the uterus after previous cesarean delivery and determine the threshold thickness of scar that would allow the completion of birth vaginally. MATERIAL AND METHODS Conducted is prospective study of 108 pregnant women aged 20-42 years, who had previously had a Caesarean section. Diagnostic accuracy in assessing the success of scar scale by evaluation of delivery (spontaneous or caesarean section). Measurements were carried out by 2D and 3D ultrasound machines in the 20, 38-40 week of gestation and 48 hours after birth. RESULTS Tests have shown that there is a statistically significant difference in the rates of specificity (0.04), sensitivity (0.05), PPV (0.01) and NPV (0.01) between 2D and 3D ultrasound. Ultrasound images of uterine muscle scar after prior cesarean section are better by 3D methods. The marginal value, "cut-off value" thick scar, which provides the possibility of vaginal birth after previous incision was 3.5 mm. CONCLUSION The study showed that ultrasound measurement of 3D ultrasound thick scar on the uterus after previous cesarean section has practical application in determining the mode of delivery among pregnant women who have previously given birth by Caesarean section.

The sample consisted of 40 female participants extracted from a population of elementary school students from Nis, age 12 ± 6 months, who regularly participated in their physical education classes. The basic aim of the research was to determine the influence of programmed contents of regular physical education classes on the development of the motor agility and functional abilities of the participants. The research problem was the evaluation of whether under the influence of physical education in the curriculum we can achieve a statistically significant increase in the level of the motor agility and functional abilities of the participants. By using the student t-test for small dependent samples and the canonical discriminant analysis, we determined that under the influence of physical exercise, at the end of a three-month period of physical education classes, a statistically significant increase in the level of motor agility and functional abilities of the participants was determined.

The research was carried out on a sample of 55 female high school students from Nis, 15 years of age (± 6 months). The aim of the research was to determine the canonical correlations between morphological dimensions, on the one hand, and tests for the evaluation of repetitive strength on the other, among the female students. The problem of this research was the evaluation of the influence of morphological dimensions on the achieved results for repetitive strength. 10 anthropometric measurements of morphological characteristics were used, which define longitudinal dimensionality and dimensionality of the skeleton, transversal dimensionality of the skeleton and circular dimensionality and body mass. Repetitive strength was evaluated by means of three tests. The results of the canonical correlation analysis have shown that a significant canonical factor can be found between the morphological dimensions (as the predictor system) and explosive strength (as the criterion system), along with a high corre analysis.

The aim of this study was to research the impact of a diet supplemented with egg yolks of modified content, having in mind the type of fat added to the laying hens diet, on the brain lipids and their fatty acid composition in rats. During four weeks of the experiment, 64 Wistar rats, divided into four groups of 16 animals each (eight animals of both sexes), were fed the commercial rat feed (group C), or the feed that contained 70% of the commercial rat feed and 30% of freshly boiled yolks from the eggs originating from laying hens fed with 3% fish oil (group F), 3% palm olein (group P) or 3% lard (group L). Concentration and content of total lipids and total cholesterol, as well as the fatty-acid composition of the total brain lipids were determined in the lipid extracts of the rats brains. Under unfavourable conditions, which in our case could be high dietary intake of the total fat due to egg yolk addition, the amount of total fat in the brain tissue or the mass of the organ itself can be changed. Applied dietary treatments could also influence the level of de novo synthesis of total cholesterol in the rat brain. High dietary fat intake, as well as the fat quality regarding its fatty acid composition, appear to be able to significantly influence the fatty acid profile of the total brain lipids in adult rats, whereas the level and quality of the changes also depend on sex.

The aim of this study was to examine the effects of diets supplemented with egg yolks of modified composition on the fatty-acid composition and lipid content in rat’s liver. During four weeks of the experiment 64 Wistar rats were divided into four groups of 16 individuals each (eight individuals of both sexes) and fed a commercial feed mixture for rats (group C) or diet containing 70% commercial mixture for rats and 30% freshly cooked egg yolks from laying hens fed diets with 3% fish oil (group F), 3% palm olein (group P) or 3% lard (group L). Dietary supplementation with egg yolks significantly increased the hepatic cholesterol pool in rats, regardless of the type of fat in the diet of laying hens from which the eggs originated. The content of α-linolenic acid in the liver of male rats in group P was 4-6 times higher compared to males in the other groups. Liver lipids and their fatty-acid composition differ by both, sex and dietary modified egg yolk composition in rats.

Goal: To investigate the correlation between TSH and HbA1c in the treatment of L-thyroxine in the process of glycemic control in patients with subclinical hypothyroidism. Patients and methods: The sample consisted of 100 patients, mean age 51.75±3.23 years, BMI=27.97±4.52 kg/m2, with SH (TSH>4.2 mU/L and normal serum T3 and T4). Laboratory diagnosis included the determination of free T3, free T4, thyroid antibodies, Tg, insulin, C-peptide and glucose during the OGTT, HbA1c, CRP and lipid levels. 20 patients with SH had prediabetes and 38 patients had DM. All patients were treated with low doses of L-thyroxine (25-50ug) and all were physically active. Results: After 6 months of treatment with L-thyroxine, the patients had normal or decreased TSH (5.85±0.92 vs. 3.54±0.55 mU/L), insulin levels (114.64±24.11 vs. 96.44±17.26 pmol/L) significantly reduced HbA1c (6.74±1.01 vs. 6.26±1.12) is reduced. Conclusion: The correlation between TSH and HbA1c was positive and significant (r=0.46). This indicates a significant effect of treatment with L-thyroxine on glycemic control in patients with subclinical hypothyroidism.