In this paper we study the notion of a graded $\Omega$-group $(X,+,\Omega),$ but graded in the sense of M.~Krasner, i.e., we impose nothing on the grading set except that it is nonempty, since operations of $\Omega$ and the grading of $(X,+)$ induce operations (generally partial) on the grading set. We prove that graded $\Omega$-groups in Krasner's sense are determined up to isomorphism by their homogeneous parts, which, with respect to induced operations, represent partial structures called $\Omega$-\emph{homogroupoids}, thus narrowing down the theory of graded $\Omega$-groups to the theory of $\Omega$-homogroupoids. This approach already proved to be useful in questions regarding A. V. Kelarev's $S$-graded rings inducing $S,$ where $S$ is a partial cancellative groupoid. Particularly, in this paper we prove that the homogeneous subring of a Jacobson $S$-graded ring inducing $S$ is Jacobson under certain assumptions. We also discuss the theory of prime radicals for $\Omega$-homogroupoids thus extending results of A.~V.~Mikhalev, I.~N.~Balaba and S.~A.~Pikhtilkov in a natural way. We study some classes of $\Omega$-homogroupoids for which the lower and upper weakly solvable radicals coincide and also, study the question of the homogeneity of the prime radical of a graded ring.

Abstract Background. Endovascular embolization is a treatment of choice for the management of unruptured intracranial aneurysms, but sometimes is complicated with perianeurysmal oedema. The aim of our study was to establish incidence and outcomes of perianeurysmal oedema after endovascular coiling of unruptured intracranial aneurysms, and to reveal possible risk factors for development of this potentially serious complication. Methods. In total 119 adult patients with endovascular embolization of unruptured intracranial aneurysm (performed at Department for Interventional Neuroradiology, Clinical Center, Kragujevac, Serbia) were included in our study. The embolizations were made by electrolite-detachable platinum coils: pure platinum, hydrophilic and combination of platinum and hydrophilic coils. Primary outcome variable was perianeurysmal oedema visualized by magnetic resonance imaging (MRI) 7, 30 and 90 days after the embolization. Results. The perianurysmal oedema appeared in 47.6% of patients treated with hydrophilic coils, in 21.6% of patients treated with platinum coils, and in 53.8% of those treated with mixed type of the coils. The multivariate logistic regression showed that variables associated with occurrence of perianeurysmal oedema are volume of the aneurysm, hypertension, diabetes and smoking habit. Hypertension is the most important independent predictor of the perianeurysmal oedema, followed by smoking and diabetes. Conclusions. The results of our study suggest that older patients with larger unruptured intracranial aneurysms, who suffer from diabetes mellitus and hypertension, and have the smoking habit, are under much higher risk of having perianeurysmal oedema after endovascular coiling.

'The problem of Socrates' represents one of the most important issues in the history of ancient philosophy. It is about credibility and foundation of sources that reveal the 'face' of the historical Socrates. In fact, in recent years researchers have disputed about it, where one of four sources (Aristophanes, Plato, Xenophon and Aristotle) belongs to the highest degree of certainty for the reconstruction of the historical character of the philosophers of Athens. The author will take up this issue on the basis of recent studies and show how the dialogues of Plato and Xenophon writings show as the most reliable written records to define the philosophical portrait of Plato's teacher.

This paper describes a structural analysis of the CAD model three versions fixators Sarafix which is to explore the possibility of introducing composite materials in the construction of the connecting rod fixators comparing values of displacement and stiffness at characteristic structure points. Namely, we have investigated the constructional performance of fixators Sarafix with a connecting rod formed from three different composite materials, the same matrix (epoxy resin) with three different types of fibers (E glass, kevlar 49 and carbonM55J). The results of the structural analysis fixators Sarafix with a connecting rod made of composite materials are compared with the results of tubular connecting rod fixators made of stainless steel. After comparing the results, from the aspect of stiffness, we gave the final considerations about composite material which provides an adequate substitution for the existing material.

BackgroundCoccidiosis is the most common and costly disease in the poultry industry and is caused by protozoans of the Eimeria genus. The current control of coccidiosis, based on the use of anticoccidial drugs and vaccination, faces serious obstacles such as drug resistance and the high costs for the development of efficient vaccines, respectively. Therefore, the current control programs must be expanded with complementary approaches such as the use of genetics to improve the host response to Eimeria infections. Recently, we have performed a large-scale challenge study on Cobb500 broilers using E. maxima for which we investigated variability among animals in response to the challenge. As a follow-up to this challenge study, we performed a genome-wide association study (GWAS) to identify genomic regions underlying variability of the measured traits in the response to Eimeria maxima in broilers. Furthermore, we conducted a post-GWAS functional analysis to increase our biological understanding of the underlying response to Eimeria maxima challenge.ResultsIn total, we identified 22 single nucleotide polymorphisms (SNPs) with q value <0.1 distributed across five chromosomes. The highly significant SNPs were associated with body weight gain (three SNPs on GGA5, one SNP on GGA1 and one SNP on GGA3), plasma coloration measured as optical density at wavelengths in the range 465–510 nm (10 SNPs and all on GGA10) and the percentage of β2-globulin in blood plasma (15 SNPs on GGA1 and one SNP on GGA2). Biological pathways related to metabolic processes, cell proliferation, and primary innate immune processes were among the most frequent significantly enriched biological pathways. Furthermore, the network-based analysis produced two networks of high confidence, with one centered on large tumor suppressor kinase 1 (LATS1) and 2 (LATS2) and the second involving the myosin heavy chain 6 (MYH6).ConclusionsWe identified several strong candidate genes and genomic regions associated with traits measured in response to Eimeria maxima in broilers. Furthermore, the post-GWAS functional analysis indicates that biological pathways and networks involved in tissue proliferation and repair along with the primary innate immune response may play the most important role during the early stage of Eimeria maxima infection in broilers.

Coccidiosis is the most common and costly disease in the poultry industry and is caused by protozoans of the Eimeria genus. The current control of coccidiosis, based on the use of anticoccidial drugs and vaccination, faces serious obstacles such as drug resistance and the high costs for the development of efficient vaccines, respectively. Therefore, the current control programs must be expanded with complementary approaches such as the use of genetics to improve the host response to Eimeria infections. Recently, we have performed a large-scale challenge study on Cobb500 broilers using E. maxima for which we investigated variability among animals in response to the challenge. As a follow-up to this challenge study, we performed a genome-wide association study (GWAS) to identify genomic regions underlying variability of the measured traits in the response to Eimeria maxima in broilers. Furthermore, we conducted a post-GWAS functional analysis to increase our biological understanding of the underlying response to Eimeria maxima challenge. In total, we identified 22 single nucleotide polymorphisms (SNPs) with q value <0.1 distributed across five chromosomes. The highly significant SNPs were associated with body weight gain (three SNPs on GGA5, one SNP on GGA1 and one SNP on GGA3), plasma coloration measured as optical density at wavelengths in the range 465–510 nm (10 SNPs and all on GGA10) and the percentage of β2-globulin in blood plasma (15 SNPs on GGA1 and one SNP on GGA2). Biological pathways related to metabolic processes, cell proliferation, and primary innate immune processes were among the most frequent significantly enriched biological pathways. Furthermore, the network-based analysis produced two networks of high confidence, with one centered on large tumor suppressor kinase 1 (LATS1) and 2 (LATS2) and the second involving the myosin heavy chain 6 (MYH6). We identified several strong candidate genes and genomic regions associated with traits measured in response to Eimeria maxima in broilers. Furthermore, the post-GWAS functional analysis indicates that biological pathways and networks involved in tissue proliferation and repair along with the primary innate immune response may play the most important role during the early stage of Eimeria maxima infection in broilers.

Background. The role of multivisceral resection, in the setting of locally advanced gastric cancer, is still debated. Previous studies have reported a higher risk for perioperative morbidity and mortality, with limited objective benefit in terms of survival. Patient. A male patient, 55 years old, was admitted to the clinic of surgery for surgical treatment of bleeding gastric ulceration. Preoperative diagnostic evaluation was performed, and patient had undergone a surgical treatment which revealed a large mass in head of the pancreas, infiltrating the hepatoduodenal ligament and transverse mesocolon. Total gastrectomy, duodenopancreatectomy, and right hemicolectomy were performed. The digestive tube continuity was reestablished by deriving the double Roux limbs. Conclusion. The aim of this case presentation is to demonstrate a method of digestive tube reconstruction by performing the double Roux-en-Y reconstruction in advanced gastric cancer when the multivisceral resection is performed.

De nombreuses études ont montré que l'intelligence émotionnelle (IE) permet de prédire différents comportements cognitifs émotionnels et sociaux (Di Fabio, Palazzeschi, Asulin-Peretz et Gati, 2013; Fugate, Kinicki & Ashfort, 2004; Joseph & Newman, 2010; Salovey et Mayer, 1990; Van Rooy & Viswesvaran, 2004) le bien-être psychologique et physique ainsi que la santé mentale (Martins, Ramalho & Morin, 2010; Schutte, Malouff, Thorsteinsson, Bhullar & Rooke, 2007). En outre, les recherches étudiant les effets des formations en Compétences Émotionnelles (CE) montrent que ces dernières permettent d’améliorer certaines dimensions cognitives, émotionnelles et comportementales liées à la santé (Schutte, Malouff & Thorsteinsson, 2013). Notre recherche examine si (a) les CE peuvent être développée chez les adultes chômeurs, (b) si ces effets de formation sont modérés par la durée du chômage et (c) si les changements en CE contribuent aux changements de bien-être physique et psychologique (étude 1). Nous faisons par ailleurs l’hypothèse que les perspectives d'employabilité des chômeurs adultes peuvent être améliorées après la formation (étude 2). La recherche d'emploi est testée, comme un possible facteur déterminant des effets de l'intervention, de même que nous examinons si les changements en CE sont associés aux des ressources et des stratégies d'adaptation (étude 3). Les résultats montrent un impact différentiel de la formation en fonction de la durée du chômage et de la recherche d'emploi. En outre, le changement dans la CE prédit de façon significative des changements dans le stress perçu, les plaintes somatiques, la santé mentale, les deux dimensions de l'humeur, la satisfaction avec la vie, l'optimisme, la qualité des relations sociales ainsi que les stratégies d'adaptation orientées vers les problèmes. En outre, l'intervention a eu des effets positifs sur l'employabilité perçue, l’employabilité réelle et l'auto-efficacité entrepreneuriale. Les résultats sont discutés au regard du potentiel de développement des CE et de l'efficacité de l'intervention en CE pour les chômeurs.