BackgroundTo validate a new practical Sepsis Severity Score for patients with complicated intra-abdominal infections (cIAIs) including the clinical conditions at the admission (severe sepsis/septic shock), the origin of the cIAIs, the delay in source control, the setting of acquisition and any risk factors such as age and immunosuppression.MethodsThe WISS study (WSES cIAIs Score Study) is a multicenter observational study underwent in 132 medical institutions worldwide during a four-month study period (October 2014-February 2015). Four thousand five hundred thirty-three patients with a mean age of 51.2 years (range 18–99) were enrolled in the WISS study.ResultsUnivariate analysis has shown that all factors that were previously included in the WSES Sepsis Severity Score were highly statistically significant between those who died and those who survived (p < 0.0001). The multivariate logistic regression model was highly significant (p < 0.0001, R2 = 0.54) and showed that all these factors were independent in predicting mortality of sepsis. Receiver Operator Curve has shown that the WSES Severity Sepsis Score had an excellent prediction for mortality. A score above 5.5 was the best predictor of mortality having a sensitivity of 89.2 %, a specificity of 83.5 % and a positive likelihood ratio of 5.4.ConclusionsWSES Sepsis Severity Score for patients with complicated Intra-abdominal infections can be used on global level. It has shown high sensitivity, specificity, and likelihood ratio that may help us in making clinical decisions.

We speculate about the origin of the recent excess at $$\sim $$∼750 GeV in diphoton resonance searches observed by the ATLAS and CMS experiments using the first 13 TeV data. Its interpretation as a new scalar resonance produced in gluon fusion and decaying to photons is consistent with all relevant exclusion bounds from the 8 TeV LHC run. We provide a simple phenomenological framework to parametrize the properties of the new resonance and show in a model-independent way that, if the scalar is produced in gluon fusion, additional new colored and charged particles are required. Finally, we discuss some interpretations in various concrete setups, such as a singlet (pseudo-) scalar, composite Higgs, and the MSSM.

The aim of this study was to validate the questionnaire of the quality of integration of a subject into the school curriculum. For this purpose, 200 teachers of Religious education and 200 teachers of other elementary school subjects were examined in a survey on the quality of integration of a subject into the school curriculum, and the content of the questionnaire was leaning against the implementation of the ISSA pedagogical standards in teaching process. The first version of the questionnaire of the quality of integration into the school curriculum was composed of nine subscales: Educational social context, Hidden curriculum as an indicator of the actual integration, Contribution of school subjects to the development of an integrated school curriculum, Frameworks for creating a subject curriculum as a basis for the integration into the school curriculum, Inter-subject correlation as a function of the integrated curriculum, Teamwork and inclusion in the function of the development of an integrated curriculum, Contribution of textbooks to the integration of curriculum, Assessment in order to develop excellence as the segment of evaluation of the implementation of the curriculum, and Contribution of the subject curriculum to the overall development of the student’s personality. The questionnaire consisted of a total of 118 items. The analysis of particles belonging to certain factors, in the results of the survey, lead to a restructure of the research questionnaire and the allocation of new factors which resulted in creating new 6 subscales: The contribution of a subject teacher to the development of an integrated school curriculum, Synergistic impact of school factors on the development of an integrated school curriculum, The focus of a subject curriculum on the personality development of students, The Quality of educational social context, Meeting the special needs of students and Integration quality of a textbook. The final version of the questionnaire consisted of 99 items. The results showed high reliability on the subscales individually and high reliability of the instrument in its entirety, because it showed that Cronbach alpha coefficient for the entire instrument is 0.958.

The male-female relationship constitutes an eternal enigma analysed in different ways throughout the history. The status of women through the ages has been significantly different from the status of men; the domestic domain of their home has been regarded as a female space, while the public life has been reserved for males. Women have been invisible in many aspects of life; the procreation has been viewed as their most important function, while not protesting and accepting the fate in silence have been considered their highest virtues. The present paper illustrates how this topic is described in proverbs, and the contrastive analysis sheds light on the similarities/differences between the conception of women, men and the relationship between them in two languages: B/C/S and English. Although the results indicate that in both languages the dichotomy male-female does not divide the world into two symmetrical parts with regard to the power, freedom and rights being marked by the male dominance, the inequality is more visible in B/C/S.