Goal: The goal of this study was the determination of the effects in treatment of early stage (<IIB) and locally advanced stages (≥IIB) of uterine cervical carcinoma by using MRI. Material and Methods: The study was a prospective, comparative, analytical, and observational and included 74 patients with cervical cancer (PH confirmed). All 74 patients have initially gone through the pre-therapeutic MRI to determine the tumour FIGO stage. At a renewal of the initial MRI findings, patients were divided into two study groups: group A and group B. Group A consisted from 39 patients with early-stage cervical carcinoma (<IIB) and group B comprised from 35 patients with locally advanced stage (≥IIB). Postterapeutic MRI control, were perfomed in both group (A and B). Further MRI examinations were set for the patients from both groups. Results: An analysis of treatment outcomes in group A showed that most patients had no local recurrence or residuum disease in 89.7%, while local recurrence was observed in only 10.3% cases. An analysis of treatment outcomes in group B showed that most patients had complete regression after local chemoradiotherapy in 68.8%, while 25.7% of patients had local progression of the disease, while the 5.7% cases recorded partial local tumour regression(p<0.05). It has been shown that a complete local regression was more frequent in the case of squamous cell carcinoma in 74.2% vs 25% in adenocarcinoma cases. Also local and partial regression was observed more frequently in the case of squamous cell carcinoma in 6.5% compared to 0% in adenocarcinoma, while progression was more common in adenocarcinoma at 75% compared to 19.4% for squamous cell (p<0.05). MRI results showed positive outcome of treatment group A and B in our study, showed a statistically significant difference in favour of group A (89.7%) compared to group B 68.8% (p<0.05). Conclusion: The results obtained from our studies show that early stage cervical cancer (<IIB) shows a better outcome in treatment of advanced stages (≥IIB). In the treatment of advanced stages (≥IIB), concomitant radio chemotherapy shows significant results in terms of complete tumour regression, especially in squamous cell type of cervical cancer.

Objective: This study objective was to evaluate interobserver agreement between individual pairs of three nuclear medicine physicians in interpretation of renal cortical scintigraphy in children with respect to the mode of acquisition (planar vs. SPECT), diagnoses and kidney site (left vs. right). Materials and Methods: Thirty children were imaged in planar and SPECT mode per protocol upon the injection of Tc-99m DMSA dose adjusted to their body weight. Patients were classified according to diagnoses into four groups. Three nuclear medicine physicians interpreted the findings blindly and independently. Renal defects were interpreted as focal and diffuse, per three renal segments. For the raters we calculated simple percentage agreement, the Cohen kappa statistic with 95% confidence intervals, and the overall kappa defining the levels of reliability as almost perfect or perfect, substantial, moderate, fair and slight agreement. Results: Interobserver agreement in planar interpretation was 77,2% (kappa=0.59; 95% confidence interval, 0.41 to 0.75) and SPECT 72,9% (kappa= 0,57; 95% confidence interval, 0,41 to 0,72). In planar interpretation, all individual pairs had moderate agreements except one that had a substantial agreement. In SPECT, all the pairs had moderate agreements except one that had an almost perfect agreement. Overall agreement per kidney site was on planar 73,4% for the left (kappa=0,54, moderate agreement), and 81,1% for the right kidney (kappa 0,63, substantial agreement). On SPECT, there was 72,2% agreement for the left (kappa=0,59, mode rate agreement), and 73,7% for the right kidney (kappa=0,54, moderate agreement). Overall agreement per diagnoses ranged from 70-88,9% on planar (kappa= -0,04 to 0,79), and 50-100% on SPECT (kappa=-0,02-1,000) indicating agreements from slight to substantial. Discussion: Our results suggest acceptable levels of interobserver agreement in all individual pairs of raters with respect to the mode of acquisition (planar vs. SPECT), diagnoses and kidney site (left vs. right). For the mode of acquisition, we would recommend hybrid imaging SPECT/CT method to be used whenever possible in the detection of renal cortical defects on Tc-99m-DMSA scintigraphy.

Objective: To investigate possible prognostic values of CD4+, CD8+ T-lymphocytes, CD4/CD8 ratio to clinical course of chickenpox in immunocompetent hosts. Materials and methods: We performed a prospective study which included 69 immunocompetent patients with chickenpox who were addmited to Clinic for infectious disease, Clinical Center University of Sarajevo, in a 18 month period. All patients were divided into two groups depending on clinical presentation on admission. Patients with mild clinical form were dedicated to „outpatient” group, and patients with moderate, severe or life-threatening clinical forms were dedicated to „hospitalized” group. Also 30 healthy volunteers are included in study as a control group. We analyzed values of CD4+, CD8+ percentage, CD4/CD8 ratio with comparison to clinical course of chickenpox. All specimens were taken in acute phase of illness. Results: Values of CD4+ percentage were significantly declined in a group of hospitalized patients, compared to group of outpatients and control group. Values of CD8+ percentage were higher in a group of hospitalized patients, while CD4/CD8 values were lower in comparison to a group of outpatients and control group. Conclusion: We found significant correlation between these parameters and clinical course of chickenpox.

Poznavanje položajne točnosti geoprostornih informacija o šumama, dobivenih interpretacijom satelitskih snimaka, ima veliko značenje. Posljedice odluka koje su temeljene na podacima nedovoljne ili nepoznate kvalitete mogu biti vrlo negativne. U ovome radu istražena je točnost zatvorenih linijskih objekata kojima su predstavljene granice šumskog pokrova. Implementacijom postupka segmentacije snimke korištenjem svih multispektralnih kanala te klasifikacijom tako definiranih segmenata pomoću posebnih pravila, efikasno su izdvojene površine pod šumama. Empirijskom analizom temeljenom na usporedbi testnog i referentnog linijskog sadržaja, pokazano je da kartografska generalizacija doprinosi poboljšanju točnosti granica šuma, te da adekvatna obrada podataka daljinskih istraživanja srednje prostorne rezolucije može rezultirati vektorskim podacima zadovoljavajuće kvalitete.

Even though clustering algorithms in Wireless Sensor Networks (WSN) are a well investigate subject, the increasing interest in the Internet of Things (IoT) and 5G technologies has precipitated the need of new ways to comprehend and overcome a new set of challenges. While studies mainly propose new algorithms and compare these algorithms based on a set of properties (e.g. energy efficiency, scalability), none of them focuses on the underlying mechanisms and organizational patterns that lead to these properties. We address this lack of understanding by applying a complex systems science approach to investigate the properties of WSNs arising from the communication patterns of the network nodes. We represent different implementations of clustering in WSNs with a functional topology graph. Moreover, we employ a complexity metric - functional complexity (CF) - to explain how local interactions give rise to the global behavior of the network. Our analysis shows that higher values of CF indicate higher scalability and lower energy efficiency.

The cranes are now not replaceable mode of transport of materials and finished products both in production halls and in the open space. This paper made the whole analytical calculation of double girder bridge cranes to be used in laboratories exclusively for testing, determined by the maximum bending stress and deflection of the main girder. After calculating the dimensions, we created a model cranes in software CATIA V5. The same model was subjected to FEM analysis of the same name software. At the end of the paper comparison has been done. The objective of the calculation and analysis of the model was to develop a model crane and to serve for the next tests. Dimensions of the crane are given according to the laboratory where it will be located.

In this paper will be observed the population dynamics of a three-species Lotka-Volterra model: two predators and their prey. This simplified model yields a more complicated dynamical system than classic Lotka-Volterra model. We will give the conditions under which one of the predators becomes extinct and when the coexistence between predators is possible. Given will be sufficient conditions for the existence of solutions for certain classes of Cauchy’s solutions of Lotka-Volterra model. The behavior of integral curves in the neighborhoods of an arbitrary integral curves will be considered.

Objective. To compare the development of permanent teeth in a group of children with the congenitally missing permanent teeth (CMPT) and corresponding nonaffected group. Methods. The formation stages of all developing permanent teeth were determined on 345 panoramic radiographs (OPTs) by the method of Haavikko (1970), and dental age was calculated. The paired samples t-test was used to compare the differences between dental age (DA) and chronological age (CA) in those with CMPT and those not affected. Spearman test was used to evaluate the correlation between DA-CA and the number of missing teeth. The Wilcoxon signed rank test was used to compare the development of the teeth adjacent to the place of the agenesis with matched pair in corresponding nonaffected group. Results. Dental age was significantly delayed in CMPT children compared to the nonaffected group (p < 0.001). The mean differences were −0.57 ± 1.20 years and −0.61 ± 1.23 years in males and females, without difference between sexes (p = 0.763). The number of missing teeth affected the delay only in females (p = 0.024). Only mesial teeth in females were significantly delayed in development when compared to the nonaffected group (p = 0.007). Conclusion. Our findings show that the development of the permanent teeth is delayed when compared to the nonaffected group of the same sex and age.