UDK: 630*38:625.711.84(497.6 Trnovo) The forest truck roads, as one of the essential conditions for implementation of the planned biotechnical measures in the management unit, have to have an adequate quantity and quality. The aim of this research is determination of quantity and quality of the forest truck roads in the Management Unit (MU) „Gornja Rakitnica“, Forest Management Region (FMR) „Trnovsko“. The accessibility through wider categories of forest and total accessibility for MU have been calculated by the analysis of quantities indicators of the primary network of roads. The accessibility of the most important category of forests, from economy aspect, has been calculated – the forests with natural renewal. This accessibility amounts 12,7 m/ha. By the comparison of the values with the recommended minimum and optimum accessibility, it has been calculated that it is necessary to construct new forest truck roads. The data about quality have been obtained on the basis of terrain measurements in two forest truck roads „Rakitnica-Zućina vrela“ and „Pijevac – Borovac“. By the analysis of qualitative indicators in the analyzed roads it has been concluded that the network of forest truck roads in the MU „Gornja Rakitnica“ is passable i.e. it enables implementation of planned activities from all forest fields. The technical elements of the measured roads enable the values defined by technical regulations. The constructive elements: carriageway condition, slope cuttings, ditches and objects on the road are not in an adequate condition. If the adequate recovery works are not undertaken it could cause progressive deterioration of roads, which could influence functionality of roads transport of timber, access to compartments, etc… For the improvement of the condition of forest truck roads, the measures of recovery have been designed and the calculation of total and average costs has been carried out.

Introduction: Hospital-acquired infections (HAI) and surgical site infections (SSI) are a global public health problem. The aim of the study was to determine the incidence of SSIs at the Surgical Clinics of the University Clinical Centre Banja Luka and to identify risk factors for the development of SSIs. Methods: In order to determine the frequency of SSIs through the incidence compared to the patients operated at the Surgical Clinics of the University Clinical Centre Banja Luka, we conducted a prospective cohort study which encompassed 11.216 operated patients, in the period from November 11th, 2014 to September 30th, 2015. In order to identify risk factors for the development of SSIs, a nested case-control study of risk factors for SSIs was conducted. The study group consisted of patients who were diagnosed with SSIs in the period of monitoring, while the control group was consisted of patients without SSIs who corresponded with the study group in age and sex. Results: The highest values of incidence of SSIs were observed at the Department of Anesthesia and Intensive Care (2.65%), Department of Orthopaedic Surgery (2.48%) and the Department of Vascular Surgery (2.15%), and the lowest ones at the Department of Urology (0.59%). Among the cases of SSIs, deep infections of the surgical site were the most represented (82.7%). Multivariate logistic regression was used to identify the following independent risk factors: length of pore-operative stay in hospital (p=0.000; OR=1.062; 95% CI=1.037-1.087), reintervention (p=0.000; OR=22.409; 95% CI=6.361-79.071) and cotrticosteroids (p=0.023; OR=4.141; 95%CI=1.221-14.047). Conclusion: The incidence of SSIs at the Surgical Clinics of the University Clinical Centre Banja Luka is at the level of hospitals in developed countries. There are a number of risk factors for SSIs, which may be prevented.

UDK: 630*81:674.031.632.2(497.6 Kladanj)            582.632.2:674.038.17(497.6 Kladanj) There are many factors that affect appearance and spreading of the red heart in beech stands. Therefore, this research presents an analysis of site quality class and taxation elements (diameter at the breast height, height of the tree and age of the tree) influence on the participation and distribution of the red heart in the forest compartments 107. M.U. „Gosteljaˮ - (II- quality class) and 47. M.U. „Srednja Drinjačaˮ - (III- quality class). The appearance of the red heart on the beech trees considering on the site quality class was researched, as well as the red heart appearance frequency in dependence on the tree diameter at the breast height and age of the tree, size and distribution of the red heart in the longitudinal and transverse direction. The results of research showed that the number of trees with the red heart and the length of the technical roundwood with the red heart increase with increase of diameter at the breast height (age of the tree). As well, it was established that the appearance frequency of the trees with red heart considering the diameter at the breast height (the age of the tree) was larger on the stands belonging low quality site classes. The site quality class affects the distribution of the red heart at the thicker beech trees in the longitudinal direction, while at the thinner and trees of medium diameter, the influence of site quality class on the distribution of the red heart is not expressed in great extent. Larger diameters of the red heart in average have beech trees on the low quality site classes.

UDK: 630*228(234.422 Bjelašnica)(253) This paper presents the results of a comparative analysis of the structural and vegetation characteristics of "Ravna vala" pristine (virgin) forest and the managed forest of beech and fir (with spruce). Pristine forest "Ravna vala" is located in the central part of Bosnia and Herzegovina, about 20 km southwest of Sarajevo on Bjelašnica Mountain, at an altitude from 1280 to 1450 m. The managed forest of beech and fir with spruce, which was used for comparison, borders "Ravna vala" and has the same habitat conditions: climate, orography and land, and the similar structural characteristics and composition of tree species as the pristine forest. Beech and fir communities (Abieti-Fagetum illyricum Treg. 1957) dominate but spruce can also be found in the area of ​​research. Noble hardwoods such as sycamore and elm are found both individually or in small groups in depressions in deeper soils. Both the pristine forest and the managed forest show the selective diameter structure. However, the great differences between the pristine forest and the managed forest are final diameter classes. The thickest tree in the pristine forest has the breast diameter of 145 cm, while the diameter of the thickest tree in the industrial forest is 70 cm. The volume of the stands is 770 m3/ha in the pristine forest and it is two times larger than in the managed forest. The volume of dead wood in the pristine forest is 170 m3/ha and it is five times larger than in the managed forest. While stumps and thicker branches are the most common in the stock of dead trees in the managed forest, the most common in the stock of dead wood in the pristine forest are tall stumps as well as lying and standing dead trees. Floristic researches have shown that selective management does not reflect negatively on floristic diversity, but ground vegetation is richer in species in the managed forest. Shannon's diversity index and evenness index of vascular flora have higher values ​​in the managed forest. Unlike floristic diversity, the stand diversity index of Jähne & Dohrenbusch (1997) shows higher values ​​in the pristine forest than in the managed forest.

Introduction Monitoring the success of treatment with inhaled corticosteroid fluticasone propionate type comparing with inbibitor of leukotriene, montelukast in preschool children is an everyday topic. Control of chronic obstructive pulmonary disease is one of the most important issues today in paediatrics, especially in paediatric pulmonology. Objective Improving control of chronic obstructive pulmonary disease in children at an early stage of the disease from twelve months by the age of four. Methods The study included all children between the ages of twelve months to four years of age with obstructive bronchitis in the dispensary Centre Sarajevo. Total 360 children divided into three age groups and the same number use two different drug fluticasone propionate inhaled or montelukast in the form of granules in sixty sick children in each age subgroup. Authors were excluded children with antibiotic therapy in this reasearch. Results The drug of fluticasone propionate proved slightly more effective in controlling these diseases in the percentage of 96% relative to other drug montelukast with 93% of the total of all age groups. No significant differences in age groups and in relation to sex of children. Conclusion Both drug and fluticasone propionate and montelukast have shown excellent disease control but can not be given to any advantage in monitoring chronic obstructive pulmonary disease in preschool children.

Introduction: Bosnia and Herzegovina has one of the highest unemployment rates in the Balkan region (43.2%), so unemployment is one of the most serious public concerns in our country. Aim: To analyze the influence of unemployment on mental health of the working age population who attend primary care center. Material and Methods: The study was carried out in the municipality of Bosanska Krupa, which has the highest unemployment rate in the Federation of Bosnia and Herzegovina (56%), and included 510 randomly selected working age patients (aged 23-65 years). We used the General Health Questionnaire-28 (GHQ-28) to evaluate mental health of the working age population. Results: There were significantly more women than men (53.5% vs. 46.5%; p=0.02). The mean age of participants was 51.04±12.84 years. The experimental group included 318 (62.35%) unemployed working age participants: 160 (50.3%) had been unemployed for more than 5 years and had had no work experience, while 158 (49.7%) unemployed participants had had a previous work experience of more than five years. The control group included 192 (37.65%) employed working age participants. Unemployment had a significant influence on mental health of the working age population. The unemployed participants had a significantly poorer mental health compared to the employed (p=0.0003). A predictor of impaired mental health was a job loss. A significantly greater mental health impairment occured in the group of unemployed participants with previous work experience of more than five years compared to the unemployed participants who had had no work experience (p=0.001) and employed (p=0.000). Conclusion: Unemployment has a negative impact and leads to impaired mental health of the working age population in Bosnia and Herzegovina. A job loss has a predictive role. It indicates that social and health policies must be developed in order to improve well-being of the working age population.

Activation of the STAT5 signaling pathway up‐regulates antiapoptotic protein Bcl2 and drives proliferation of autoreactive conventional CD4 T cells (Tcons). In systemic lupus erythematosus (SLE), an increased T cell Bcl2 content and perturbed homeostasis of CD45RA−FOXP3hi activated regulatory T cells (aTregs) were described. We assessed Tcon/Treg subsets and phosphorylation of STAT5 (pSTAT5) in blood T cells from patients with SLE by using conventional and imaging flow cytometry. Forty‐one patients with SLE, 33 healthy controls, and 29 patients with rheumatoid arthritis were included. Long‐term monitoring was performed in 39 patients with SLE, which were followed longitudinally for up to 1000 d. Significantly increased Bcl2 protein content in T cells from patients with SLE was associated with IL‐7–dependent STAT5 activation, expressed as increased basal levels and nuclear localization of pSTAT5. pSTAT5 levels were significantly increased in the FOXP3 low‐expressing CD4+ T cell subsets but not in the aTreg subset, which was significantly decreased in patients with SLE. In contrast to aTreg, SLE Tcon displayed significantly increased pSTAT5 and Bcl2 levels. Moreover, the percentage of Tcon‐expressing proliferation marker Ki‐67 was significantly increased in patients with SLE and was positively correlated with CD4 T cell pSTAT5 levels. Finally, a subgroup of patients characterized by an increased Tcon–pSTAT5/aTreg–pSTAT5 ratio experienced a more aggressive‐relapsing disease course and displayed higher time‐adjusted cumulative CD4 T cell pSTAT5 levels during follow‐up, which were positively correlated with time‐adjusted cumulative disease activity. Our results indicate that imbalanced STAT5 phosphorylation, which is related to Bcl2 and Ki‐67 expression, may confer survival and proliferative advantage to Tcon over aTreg and could represent a possible marker of SLE disease severity.