This paper presents a generic method to enhance performance and incorporate temporal information for cardiorespiratory-based sleep stage classification with a limited feature set and limited data. The classification algorithm relies on random forests and a feature set extracted from long-time home monitoring for sleep analysis. Employing temporal feature stacking, the system could be significantly improved in terms of Cohen’s κ and accuracy. The detection performance could be improved for three classes of sleep stages (Wake, REM, Non-REM sleep), four classes (Wake, Non-REM-Light sleep, Non-REM Deep sleep, REM sleep), and five classes (Wake, N1, N2, N3/4, REM sleep) from a κ of 0.44 to 0.58, 0.33 to 0.51, and 0.28 to 0.44 respectively by stacking features before and after the epoch to be classified. Further analysis was done for the optimal length and combination method for this stacking approach. Overall, three methods and a variable duration between 30 s and 30 min have been analyzed. Overnight recordings of 36 healthy subjects from the Interdisciplinary Center for Sleep Medicine at Charité-Universitätsmedizin Berlin and Leave-One-Out-Cross-Validation on a patient-level have been used to validate the method.Clinical relevance— The method can be employed generically to feature sets for (small scale) datasets to improve classification performance for classification problems with temporal relations with random forest classifiers.

Introduction. Despite its high accuracy, polysomnography (PSG) has several drawbacks for diagnosing obstructive sleep apnea (OSA). Consequently, multiple portable monitors (PMs) have been proposed. Objective. This systematic review aims to investigate the current literature to analyze the sets of physiological parameters captured by a PM to select the minimum number of such physiological signals while maintaining accurate results in OSA detection. Methods. Inclusion and exclusion criteria for the selection of publications were established prior to the search. The evaluation of the publications was made based on one central question and several specific questions. Results. The abilities to detect hypopneas, sleep time, or awakenings were some of the features studied to investigate the full functionality of the PMs to select the most relevant set of physiological signals. Based on the physiological parameters collected (one to six), the PMs were classified into sets according to the level of evidence. The advantages and the disadvantages of each possible set of signals were explained by answering the research questions proposed in the methods. Conclusions. The minimum number of physiological signals detected by PMs for the detection of OSA depends mainly on the purpose and context of the sleep study. The set of three physiological signals showed the best results in the detection of OSA.

Osnovna funkcija univerziteta, pored obrazovanja, je naučnoistraživački rad. Na bosanskohercegovačkim univerzitetima je naučnoistraživački rad zapostavljen. Dva su osnovna razloga za to. Prvi je nedovoljno finansijsko ulaganje u nauku i istraživanja, a drugi je nedovoljno razvijena svijest o značaju naučnoistraživačkog rada, kako u bosanskohercegovačkom društvu, tako i na samim univerzitetima. U ovom radu je ukazano na to šta je potrebno uraditi da se ova druga teškoća prevaziđe. Pored toga, analizirane su mogućnosti unapređenja nauke i oblikovanja sistema nauke na bosanskohercegovačkim univerzitetima, kako bi oni postali i istraživački univerziteti. Na naučnoistraživački rad se nadovezuju istraživačko-razvojni rad, tehnološki razvoj, saradnja s privredom i razvoj naučno-tehnoloških parkova. Ove djelatnosti su još manje zastupljene na bosanskohercegovačkim univerzitetima nego naučnoistraživački rad. U ovom radu je ukazano na načine kako prevazići te teškoće, kako bi istraživački univerziteti postali nosioci tehnološkog razvoja Bosne i Hercegovine.

The primary function of the university, in addition to education, is scientific research. At Bosnia and Herzegovina universities, the scientific research has been neglected. There are two basic reasons for that. The first is insufficient financial investment in science and research, and the second is an underdeveloped awareness of the importance of scientific research work, both in the society of Bosnia and Herzegovina and in universities themselves. This paper indicates what needs to be done to overcome this latter difficulty. In addition, the possibilities for improving science and shaping the science system at universities in Bosnia and Herzegovina to make them research universities were analysed. Scientific research work builds on research and development work, technological development, cooperation with the economy and the development of science and technology parks. These activities are even less represented at universities in Bosnia and Herzegovina than scientific research work. This paper shows the ways how to overcome these difficulties, so that research universities become carriers of the technological development of Bosnia and Herzegovina.

Simple Summary The contamination of feed with mycotoxins is a global concern, resulting in adverse effects on productivity and animal health and, therefore, a great economic loss. Ochratoxin A and T-2 mycotoxins are among the mycotoxins that contaminate animal feed. These mycotoxins could adversely affect the health of broilers, and the most effective method to mitigate the toxic effects of mycotoxins is the use of detoxifying agents. In the present experiment, broiler chickens were allotted into five groups. Group 1 received a non-contaminated diet; group 2 received a non-contaminated diet + 3 g/kg of a mycotoxin binder (MMDA); group 3 received a non-contaminated diet + 0.5 mg/kg OTA + 1 mg/kg T-2 toxin; group 4 received a non-contaminated diet + 0.5 mg/kg OTA + 1 mg/kg T-2 toxin + 1 g/kg MMDA; and group 5 received a non-contaminated diet + 0.5 mg/kg OTA + 1 mg/kg T-2 toxin + 3 g/kg MMDA for 35 days. The results revealed that OTA and T-2 toxin negatively affected the productive parameters and some blood and carcass characteristics of broiler chickens. The addition of the detoxifying agent (MMDA at 1 or 3 g/kg feed) to contaminated diets alleviated the adverse effects observed on productivity and the broilers heath related parameters. Abstract The present study was conducted to evaluate the efficacy of the feed additive, a novel multicomponent mycotoxin detoxifying agent (MMDA) containing modified zeolite (clinoptilolite), Bacillus subtilis, B. licheniformis, Saccharomyces cerevisiae cell walls, and silymarin, as detoxifiers of 0.5 mg/kg (0.5 ppm) ochratoxin A (OTA) and 1 mg/kg (1 ppm) T-2 toxin on broiler chickens. A total of 240 1-old broiler chickens (Ross 308) were randomly distributed into five different dietary treatments: (1) control (non-contaminated diet); (2) non contaminated diet + 3 g/kg of MMDA; (3) non-contaminated diet + 0.5 mg/kg OTA + 1 mg/kg T-2 toxin; (4) non-contaminated diet + 0.5 mg/kg OTA + 1 mg/kg T-2 toxin + 1 g/kg MMDA; and (5) non-contaminated diet + 0.5 mg/kg OTA + 1 g/kg T-2 toxin + 3 g/kg MMDA. The results showed that, in the starter period, from 1 to 10 days, the presence of OTA and T-2 mycotoxins reduced the consumption of feed and the growth of the broilers, and no effects of the detoxifying product were observed in the productivity of the chickens, at any of the doses tested, compared to the contaminated control (treatment 3). However, in the growing period, the same negative effect of mycotoxins was registered, but a recovery was observed in the consumption of feed and in the weight of the broilers that consumed 3 g/kg of the MMDA mycotoxin binder, reaching similar values to those of chickens fed uncontaminated control diets. The presence of mycotoxins in feed led to a reduction in the concentration of total proteins and albumin in blood compared to controls, and the presence of the detoxifying product partially reversed this effect. The breast yield of the chickens fed with mycotoxins was lower than that of the animals fed with the control feed and was not affected by the presence of the product tested, at 1 or 3 g/kg. The weight of the different organs (liver, gizzard, kidneys, or spleen), the intestinal pH, the histology of the small intestine, and oral lesions were not affected by the experimental treatments. In summary, the productive parameters and some blood and carcass characteristics of broiler chickens were impaired by the dietary presence of OTA and T-2 toxin. The tested product included at 1 or 3 g/kg feed in contaminated diets improved performance and seems to be effective in partly counteracting the deleterious effects of the tested mycotoxins.

Aktualna globalna pozicija Bosne i Hercegovine potvrđuje nalaz prethodnih istraživanja da u našoj državi ne postoji jedinstven ili barem harmonizovan i efikasan inovacioni sistem, primjeren potrebama razvoja društva i ekonomije znanja. Prvi koraci u utvrđivanju razloga ovakvog stanja su SWOT analize položaja i uloge inovacionog sistema u okviru opšteg strateškog planiranja i sektorskog planiranja istraživanja i transfera tehnologije. Najvažniji rezultati dobiveni iz tih matrica su diskutovani u radu. Oni su potom uspoređeni sa rezultatima naših najnovijih istraživanja. Prvi rezultat je sažeta SWOT matrica inovacionog sistema. Rezultate razrade pojedinih faktora smo prikazali u detaljnoj SWOT matrici zasnovanoj na elementima snage. I ova matrica je pokazala da je ujednačeno i stabilizirano visoko obrazovanje najvažniji element snage inovacionog sistema. Zbog toga su obilježja univerziteta kao subjekta inovacionog sistema posebno razmotrena.

Iterative methods are widely used for solving sparse linear systems of equations and eigenvalue problems. Their performances are relevant to the conditioning of the linear systems. This work explores factors which affects the conditioning of the discretized system, including material heterogeneity, different constitutive characteristics and element sizes, and reveals the dependencies among solvers performance and the conditioning of linear systems. Results show that multiple materials can alter the eigenvalue distributions significantly, while lowering Young’s modulus results in higher condition numbers but has less effects on the spectral scope, additionally, there is a approximately reciprocal square linear relation between element size and condition numbers. These entangled effects along with the chosen pre-conditioners render that there is no simple monotonic increasing dependency among condition numbers and solving time, except with specific conditions. It is hoped that this work will provide more understanding of the iterative sparse linear solver behavior used in similar structural problems.

Društveni značaj i kvalitet naučnog istraživanja u velikoj mjeri ovise o korisnosti rezultata istraživanja za društvenu i naučnu zajednicu. Nedostatak sredstava i želja da se sredstva dodijele visokokvalitetnim istraživanjima čine sve značajnijim procjenu kvaliteta istraživanja i valorizaciju znanja. Međutim, vrlo je teško primijeniti kriterije koji mogu objektivno procijeniti naučna istraživanja, pružajući precizne kvalitativne i kvantitativne podatke na kojima bi agencije za finansiranje mogle temeljiti svoje odluke. Proizvod naučnog istraživanja uglavnom su informacije objavljene u naučnim časopisima. One su temelj širenja znanja i osnovni kriterij za akademsku i naučnu evaluaciju, regrutovanje sredstava za naučna istraživanja i napredovanje u karijeri. Pored evaluacije naučnih publikacija, postoji širok spektar drugih aktivnosti koji odražavaju naučni kredibilitet znanstvenika, kao što su: broj i kvalitet grantova za naučnoistraživačke projekte, liderstvo u nacionalnim ili međunarodnim akademskim društvima, članstvo u redakcijama uglednih časopisa, mentorstva u doktorskim disertacijama i slično. Mada su te aktivnosti važne i daju kredibilitet znanstveniku, relevantni scientimetrijski sistemi pokrivaju samo publikacije, izostavljajući druge kriterije od naučne važnosti, u ocjenjivanju prilikom akademskog napredovanja znanstvenika, kao i konkursima za dobijanje grantova za finansijsku potporu naučnim istraživanjima. Razlog tome je činjenica da su ove aktivnosti, bez obzira na važnost, vrlo heterogene, sa specifičnim karakteristikama i zahtijevaju veoma raznolike parametre za ocjenu. Stoga, za ove aktivnosti ne postoje univerzalni kriterijumi vrednovanja i njihov se kvalitet, uglavnom, procjenjuje individualno, ovisno o namjeni procjene. Bez obzira na manjkavosti, sistemi rangiranja univerziteta su važni komparativni parametri za procjenu kvaliteta naučne i edukativne vrijednosti univerziteta.

The social significance and quality of scientific research largely depend on the usefulness of research results for the social and scientific community. The lack of funds and the desire to allocate funding to high-quality research projects make the assessment of the quality of research and the valorization of knowledge increasingly important. However, it is very difficult to apply criteria that can objectively assess scientific research, providing precise qualitative and quantitative data on which funding agencies could base their decisions. The product of scientific research is mainly information published in scientific journals. They are the basis for the dissemination of knowledge and the basic criteria for academic and scientific evaluation, fundraising for scientific research and career advancement. In addition to the evaluation of scientific publications, there is a wide range of other activities that reflect the scientific credibility of scientists, such as: number and quality of grants for scientific research projects, leadership in national or international academic societies, membership in editorial boards of reputable journals, doctoral dissertation mentorships and the like. Although these activities are important and give credibility to the scientist, the relevant scientometric systems cover only publications, neglecting other criteria of scientific importance in evaluation for purpose of academic advancement of a scientist, as well as competitions for grants for financial support of scientific research. The reason for this is the fact that these activities, regardless of their importance, are very heterogeneous, with specific characteristics, and require very diverse parameters for evaluation. Therefore, there are no universal evaluation criteria for these activities and their quality is generally assessed individually, depending on the purpose of the assessment. Regardless of the shortcomings, university ranking systems are important comparative parameters for assessing the quality of scientific and educational value of universities.

UDK: 630*9:502.1(234.422 Vranica) Nature conservation and sustainable management of forest resources become more important in Bosnia and Herzegovina, driven by the accession process toward the European Union as well as other international processes directed toward responsible management of forest resources. The forest certification has been widely adopted in the forestry sector and it implies meeting the sustainable forest management standard, whereas identification and proper management of high conservation value forests are one of the basic requirements. The NATURA 2000 ecological network is to become an important driver of reforms in the field of nature protection and forestry sector, due to the designation of new sites in forest area, which are under the responsibility of forestry institutions. This paper illustrates the scientific understanding of identification and management processes related to high conservation value forests that were proposed within potential NATURA 2000 habitats. The paper is based on analysis of main guiding principles for site designation and the role of the cross-sectoral approach applied identification and management of sites with high conservation value attributes. The case study research design was selected focusing on the Vranica Mountain due to recent activities implemented in this site. The in-depth face-to-face interviewing was used to collect qualitative data containing the key stakeholders' attitudes regarding the harmonization of NATURA 2000 habitats with the high conservation value forests – (HCVF), as well as the involvement of stakeholders in the processes of cross-sectoral cooperation. Results of this paper can be useful for the key forest and nature protection policy-makers, as well as to those responsible for managing of protected areas, or other stakeholders directly or indirectly involved in the process of identification and management of HCVFs and NATURA 2000 sites. Harmonisation of guiding principles and cross-sectoral cooperation during the identification and management of HCVFs and NATURA 2000 forest habitats enables the proper implementation of conservation and management measures based on sustainable forest management activities.