Pesticides are chemicals used in agriculture to protect crops from pests. In addition to protection during cultivation, they are also used after harvesting to extend the shelf life of products. Postharvest control stands out, especially when it comes to products imported from distant countries, resulting in increased concentration of pesticides and risk to human health consuming such products. In this study, analyses of pesticide residues were performed on 200 samples of fruits and vegetables. Pesticide residues were identified and quantified in 30 out of 200 samples. Study results revealed imazalil to be the most frequently detected pesticide. Risk assessment was performed on the obtained results, and it was carried out separately for adults and for children under 6 years of age. Imazalil showed the highest ARfD percentage for adults (max% ARfD 251%), and these values were especially high on risk assessment for children, where they amounted up to max% ARfD 1087%. The study of imazalil impact was performed on 16 Swiss albino mice divided into two groups and 4 subgroups. Experimental group animals were treated with the corresponding NOAEL dose of imazalil (10 mg/kg) for 28 days. Body weight was measured before each pesticide application on a digital electronic Sartorius scale. Peripheral blood analysis was performed after 28-day animal exposure to pesticides. Animals were anesthetized, blood samples were obtained by cardiac puncture, and red blood cell (RBC) count, hemoglobin (Hb) concentration, and white blood cell (WBC) count were determined by standard hematological methods. The organs for determination of imazalil concentration were extracted immediately upon animal sacrifice and stored in a freezer at -80°C until analysis. Results show difference in gain weight, and an increase in WBC count was recorded in the experimental group as compared with a control group of animals. The highest imazalil levels were recorded in adipose tissue (45.2‰) which proves tendency to accumulate.
Introduction: Cervical pain syndrome (CPS), or pain in the neck, is defined as a set of symptoms that limit performing movements in the upper part of the back and last more than 1 day. When the mentioned symptoms last for more than 12 weeks, we talk about chronic CPS. It often represents the condition that results from disability. It is associated with poor posture, work in sitting position, stress, and long-lasting and repetitive movements. The aim of the study was to examine the effect of physical therapy on the degree of disability, pain intensity, and daily life and work activities of persons with chronic CPS.Methods: The research was conducted in the health spa center “Reumal” Fojnica from June 2020 until July 2020. It included 50 subjects of both genders, more than 18 years old, and of all occupations, treated with physiotherapy procedures (transcutaneous electrical nerve stimulation, magnetotherapy, therapeutic ultrasound, and kinesitherapy in the form of McKenzie exercises). In addition, a pre- and post-treatment study analyzed the condition of the respondents at the first examination and the control examination after completion of treatment.Results: By analyzing the results, we established that of the total number of respondents, 74% were female, and the average age was 57.36 years. At the end of the study, the degree of disability caused by neck pain was significantly lower (p < 0.05) than the degree of disability before the therapy. Discomfort caused by symptoms of CPS that occurred and interference with work before the therapy was significantly lower (p < 0.05) after the treatment program. Therapeutic procedures have reduced the pain intensity and improved the activities of everyday life.Conclusion: The treatment with physical therapy procedures effectively reduces the degree of disability and pain intensity and improves people’s daily life and work activities with chronic CPS.
(1) University of Banja Luka, Faculty of Forestry, Department of Forest Economics and Organization, Bulevar vojvode Stepe Stepanovića 175a, BA-78000 Banja Luka, Bosnia and Herzegovina (2) University of Belgrade, Faculty of Forestry, Kneza Višeslava 1, RS-11030 Belgrade, Serbia (3) Master of Forestry, Dr Danice Perović 12, BA-78000 Banja Luka, Bosnia and Herzegovina (4) University of Sarajevo, Faculty of Forestry, Zagrebačka 20, BA-71000 Sarajevo, Bosnia and Herzegovina
The manuscript presents a model of partial discharge activity taking place in the protrusion defect inside the cable system. Through such approach COMSOL MPh provides the capacitance values obtained from the model of power cable containing defect, while conventional capacitive equivalent circuit built in MATLAB, uses these values in order to describe partial discharge activity. Having in mind that real protrusions represent non-regular shaped cavities whose analytical capacitance computation is very complex, use of COMSOL Mph facilitates capacitance computation and then provides convenient platform for the MATLAB capacitive circuit use for non-regular shaped cavities.
The main objective of this research is to establish a connection between orthodontic mini-implant design, pull-out force and primary stability by comparing two commercial mini-implants or temporary anchorage devices, Tomas®-pin and Perfect Anchor. Mini-implant geometric analysis and quantification of bone characteristics are performed, whereupon experimental in vitro pull-out test is conducted. With the use of the CATIA (Computer Aided Three-dimensional Interactive Application) CAD (Computer Aided Design)/CAM (Computer Aided Manufacturing)/CAE (Computer Aided Engineering) system, 3D (Three-dimensional) geometric models of mini-implants and bone segments are created. Afterwards, those same models are imported into Abaqus software, where finite element models are generated with a special focus on material properties, boundary conditions and interactions. FEM (Finite Element Method) analysis is used to simulate the pull-out test. Then, the results of the structural analysis are compared with the experimental results. The FEM analysis results contain information about maximum stresses on implant–bone system caused due to the pull-out force. It is determined that the core diameter of a screw thread and conicity are the main factors of the mini-implant design that have a direct impact on primary stability. Additionally, stresses generated on the Tomas®-pin model are lower than stresses on Perfect Anchor, even though Tomas®-pin endures greater pull-out forces, the implant system with implemented Tomas®-pin still represents a more stressed system due to the uniform distribution of stresses with bigger values.
Aims Social isolation in people living with schizophrenia is associated with poor quality of life and increased symptom severity. Volunteer befriending interventions are a potential strategy for addressing social isolation, but evidence of their effectiveness is limited, particularly in low- and middle-income countries. We assessed the experiences of volunteer befriending and tested its effectiveness for improving the quality of life of patients with schizophrenia in Bosnia and Herzegovina. Methods Between March 2018 and July 2020, we conducted a parallel-group, randomised controlled trial in adults with schizophrenia and poor quality of life at an outpatient clinic in Sarajevo. Patients were randomised to either the intervention, in which they were matched with a volunteer befriender with whom they met fortnightly over the 6-month intervention period, or treatment as usual. The primary outcome was quality of life measured on the Manchester Short Assessment and secondary outcomes were psychiatric symptoms and objective social outcomes. Outcome measurement was conducted by blinded researchers at 6- and 12-months. Results In total, 65 patients were randomised into the intervention (n = 33) and control arms (n = 32) and 55 (85%) completed follow-up assessments at 6 months. Patients in the intervention showed a significantly more favourable quality of life at 6 months (primary outcome; mean difference: 0.7, 95% CI [0.3–1.1], p = 0.003) and 12 months (mean difference: 1.7, 95% CI [1.1–2.3], p < 0.001). They also had significantly lower symptom levels at both follow-ups, and a significantly more favourable objective social situation after 12 months. Participants reported largely positive experiences. Conclusion The exploratory trial conducted at one site found sustained improvements in quality of life and reductions in psychiatric symptoms. This suggests that volunteer befriending may be a feasible and effective treatment for patients with schizophrenia in resource-limited contexts, such as Bosnia and Herzegovina.
Identification of key indicators that cause safety challenges and vulnerable roads is crucial for improving traffic safety. This paper, therefore, entails to the development of a novel multiphase multicriteria decision-making (MCDM) model to evaluate the vulnerability of urban roads for traffic safety. This was conducted by using data from 17 important roads of a South African city and combining several methods such as CRiteria Importance through Intercriteria Correlation (CRITIC), data envelopment analysis (DEA), and measurement of alternatives and ranking according to compromise solution (MARCOS). Taking the elements of the DEA method, two new approaches for calculating the weights of criteria, the DEA-1 and DEA-2 models, were formed and integrated with the CRITIC method to obtain the final values of criteria weights. The MARCOS method was applied to evaluate 17 alternatives, for each direction separately. The aim of developing such a model is to use the advantages of obtaining objectivity of criteria weights through linear programming and correlation of values of the collected data. Also, the MARCOS method, as one of the newer and applicable methods, provides additional significance. Extensive sensitivity analyses were conducted to validate the model. The findings suggest that there are a certain number of roads that have a high level of safety for both directions, as well as a group of risky roads, which need traffic improvement measures. Thus, the results indicate that the model is sensitive to various approaches and can prioritize vulnerable roads comprehensively based on which safety measures can be taken.
Human Y-chromosomal haplogroups are an important tool used in population genetics and forensic genetics. A conventional method used for Y haplogroup assignment is based on a set of Y-single nucleotide polymorphism (SNP) markers deployed, which exploits the low mutation rate nature of these markers. Y chromosome haplogroups can be successfully predicted from Y-short tandem repeat (STR) markers using different software packages, and this method gained much attention recently due to its labor-, time-, and cost-effectiveness. The present study was based on the analysis of a total of 480 adult male buccal swab samples collected from different regions of Bosnia and Herzegovina. Y haplogroup prediction was performed using Whit Athey’s Haplogroup Predictor, based on haplotype data on 23 Y-STR markers contained within the PowerPlex® Y23 kit. The results revealed the existence of 14 different haplogroups, with I2a, R1a, and E1b1b being the most prevalent with frequencies of 43.13, 14.79, and 14.58%, respectively. Compared to the previously published studies on Bosnian-Herzegovinian population based on Y-SNP and Y-STR data, this study represents an upgrade of molecular genetic data with a significantly larger number of samples, thus offering more accurate results and higher probability of detecting rare haplogroups.
The surface integrity of any manufactured product produced in machining process has proved to have a significant impact on the performance of the product. Many parameters influence the integrity of the surface, few of which are microstructure of the material, surface roughness, residual stresses etc. Out of which the present work focuses on the residual stress of the machining, which majorly effects the fatigue strength of the product. Understanding the significance of residual stresses in machining, and influencing it using three basic parameters: feed, cutting speed and depth of cut to increase the products performance and life by optimizing these measures to best possible combination. It is done using both experimental and numerical methods and authors have compared the numerical and experimental values. For experimental purposes AISI 1045 steel was used and the residual stresses measurement was done using X-ray diffraction method.
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