Endogenously expressed microRNAs (miRNAs) act as post-transcriptional regulators of gene expression in various (patho)physiological processes. miRNA dysregulation is frequently linked to the onset and progression of numerous diseases, hence miRNA-based therapy could be an effective strategy for treating or preventing genetic, immune, or metabolic disorders. Even though miR-27a has been identified as a promising candidate for miRNA mimic therapy of obesity, its use is restricted due to enzymatic degradation and low membrane permeability [1].

Fiber optics has revolutionized telecommunication with its superior bandwidth and distance it can span. For its use in IoT networks, some of the limiting factors are the high cost of new installations and the need to power the end device by electrical current. The installations are a part of long-term investments, and one can expect this to be an ever-smaller issue as more fibers are installed. Typically, the newly installed cables contain single-mode fibers. There are a lot of reports on transport of power over fiber, however, majority recommend using multi-mode fibers with a large core or double-clad fibers. In our approach, instead of increasing the core of the fiber, we focus on the possibility of shortening the working time of IoT devices, using the existing single-mode fiber for powering. Also, instead of an expensive PV (photo voltaic) cell with small dimensions and a high efficiency, we propose using the commercially available larger PV cells with an air gap between the end of the fiber and the cells. In accordance with our approach, we successfully conducted an experiment.

This paper presents a comprehensive treatment of the complex motion control systems in the the Sliding Mode Control (SMC) framework. The single and multi degrees of freedom (DOF) plants and applications to haptics and functionally related systems are discussed. The paper concentrates on presenting the designs that are easy to apply and tune. The proposed algorithms are based on the application of the equivalent control observer and the convergence term that guaranty stability of the closed loop in a Lyapunov sense and enforces the sliding mode on selected manifolds. Presented SMC design leads to a solution that easily could be modified to include majority of the algorithms presented in the literature.

The Western Balkan countries have been lagging behind in their transition process, which started more than 30 years ago. While some justification can be made in the fact that the countries went through wars in the 1990s, the real problem is that they have not been able to create efficient institutions. Inefficient institutions hamper economic growth, as the countries do not attract foreign direct investment (FDI) to the extent they could and should. A lack of FDI affects three aspects of the transition process in the region: developing a functioning market economy, competitiveness, and convergence. Improvements in these areas can only be done by building efficient institutions.