Linguistic errors remain a persistent challenge for B2-level EFL learners, with research showing that grammatical misapplication accounts for nearly half of the language inaccuracies. This study investigates 942 errors in argumentative essays written by Bosnian EFL learners, focusing on grammatical, lexical, and typographical challenges that impact their English writing proficiency. The data, consisting of 90 essays with a total word count of 45,786, were collected and analyzed following a structured procedure: collection, identification, description, and evaluation of learners’ errors. A descriptive-qualitative error analysis approach was employed to classify errors and examine their underlying causes systematically. To ensure reliability and consistency in the analysis, three instructors independently reviewed the essays. Inter-rater reliability was achieved through collaborative discussions, where any discrepancies in error classification were resolved through consensus. Errors were categorized into grammatical (50.2%), word-choice (29.3%), and typographical (20.5%) types and further analyzed to determine their origins as intralingual or interlingual. A deeper investigation revealed that 58% of errors were intralingual, resulting from overgeneralization and rule misapplication, while the remaining 42% were interlingual, influenced by Bosnian language interference. These findings highlight the need for focused interventions, particularly in grammar and vocabulary instruction. By uncovering error patterns and their causes, the study contributes to refining pedagogical strategies that support EFL learners’ writing proficiency.
Agency, pertaining to planning and executing actions, is a core feature of the political landscape. Our study examines the temporal dynamics of agentic language in political online discourse during the 2020 U.S. Congressional Elections, spanning 180 days before and after Election Day, and before the Capitol Hill riots. We coded 495,252 messages posted by Democratic and Republican candidates on Twitter for agentic language, which was more prevalent in tweets of politicians who won elections. Temporal analyses revealed increased agency as critical political events approached, whether a planned democratic event (Election Day) or a sudden disruptive protest (Capitol riots). The study enhances our understanding of the role of agency expression in political social media communication. Politicians may strive to evoke agency among voters to encourage political engagement, and voters may be cautioned by our results about this subtle (possibly unaware) manipulative strategy.
This study explores Sn‐doped CsPbBr3 perovskites as advanced semiconductor materials for radiation detectors. Using density functional theory, we reveal tunable band gaps from 2.803 eV (undoped) to 1.139 eV ( Sn), enabling broad‐spectrum detection from visible light to gamma rays. Optical analysis highlights high absorption coefficients in the 4‐ to 6‐eV range and enhanced visible‐light absorption, ensuring efficient photon‐to‐electron conversion. Anisotropic dielectric properties, with increasing refractive indices and dielectric constants, improve directional sensitivity and photon capture. Phonon analysis confirms dynamic stability, ensuring robustness under operational stresses and high radiation flux. The substitution of Sn for Pb reduces toxicity, offering an eco‐friendly alternative for sustainable detector technologies. These findings establish Sn‐doped CsPbBr3 as a versatile material for ‐ray spectroscopy, X‐ray imaging, and directional photodetectors, combining tunable optoelectronic properties, structural stability, and environmental sustainability to advance next‐generation radiation detection applications.
Effects of hydro-and aromatherapy on rehabilitation of patients with myocardial infarction (MI) have not yet been sufficiently investigated. This pilot study explores the anti-inflammatory effects of a combined hydro-and aromatherapy protocol in MI patients targeting inflammation. A prospective study included 22 post-MI patients undergoing 28 days of hydro-and aromatherapy at the Institute "Dr Simo Milosevic" in Montenegro. Biochemical assessments, including complete blood count and cytokine analysis, were conducted before and after treatment. Following therapy, patients exhibited increased leukocytes neutrophils, and platelets, and reduced monocytes. Fibrinogen levels significantly increased, aligning with the expected post-MI healing process. C-reactive protein (CRP) and interleukin-6 (IL-6) concentrations significantly decreased. The therapy also led to a drop in nitric oxide (NO), cortisol, dopamine, and Beclin-1 levels, highlighting potential cardiovascular benefits. These findings encourage further research with larger cohorts and extended follow-up to elucidate the long-term benefits of this protocol.
Being physically active is probably one of the most important decisions that any person can make in order to improve their own health, regardless of gender or age. For the student population, regular physical exercise is of great importance due to excessive learning and sitting. The aim of this research was to show how many students are playing sports in their leisure time, through a survey conducted on a sample of undergraduate students from the Džemal Bijedić University in Mostar. From total number of 142 participants, 76.8% of them are playing sports (63.4% recreational and 13.4% competitive), and most of them are playing team sports with the ball (23.9%) or doing sports activities in the gym (31.7%). 95.8% of students think that sports have positive impact on students life quality, which is less from the percentage of students who play sports (76.8%), so we can conclude that despite the knowledge of importance of physical activity, students don't behave regarding to what they think about sport and physical activity.
Enterprise Resource Planning (ERP) systems streamline business operations, yet many projects fail due to complexity. This research aims to predict ERP project outcomes using machine learning to identify key success and failure factors. The dataset initially contained 1,000 rows and 9 columns, but it was preprocessed to enhance data quality for machine learning analysis. It includes ERP project data from various industries, covering industry type, project scale, budget and time overruns, team experience, and technical challenges. The study applies logistic regression, decision trees, support vector machine and random forests to evaluate predictor significance. Findings reveal patterns that help forecast high-risk projects, providing project managers with a proactive decision-making framework. The results of this research offer insights into ERP project risk assessment and mitigation, enhancing strategic planning in enterprise environments.
ABSTRACT In this paper, the results of indoor radon level measurements in thirteen single-family houses, on different floors, are presented. The measurement was performed using the AlphaE radon metre device, and in each house, the measurements lasted six days, on average. The mean values of the radon activity concentration were in the range of 32.32–525.65 and 18.41–185.25 Bq m−3 for the ground floor and first floor rooms, respectively. The results of the statistical analyses on the variation of the radon level have shown that in nine houses (69 %), there is a significant difference in radon levels, with higher levels on the ground floor compared to the first floor. The variations of the radon levels during the night and daytime hours were also statistically analysed.
Plants exhibit remarkable adaptability to environmental stresses, with epigenetic modifications playing a key role in stress memory and adaptation. This review explores how epigenetic mechanisms influence hormonal regulation in plants, shaping growth, development, and stress responses. Specifically, we focus on the roles of DNA methylation, histone modifications, and small RNAs in modulating auxin, abscisic acid (ABA), gibberellin (GA), and jasmonic acid (JA) pathways. These pathways influence the plant’s ability to cope with abiotic and biotic stresses and can be inherited by progeny, enhancing stress resilience across generations. By understanding the epigenetic regulation of these hormones, we aim to provide insights into how epigenetic priming can be harnessed in crop improvement to address the challenges posed by climate change.
Background/Objectives: In consideration of the significance of the pursuit of training-induced neuroplastic changes in the stroke population, who are reliant on neurorehabilitation treatment for the restoration of neuronal function, the objectives of this trial were to investigate fMRI paradigms for acute stroke patients with ataxic symptoms, to follow up on changes in motor function and balance due to recovery and rehabilitation, and to investigate the different effects of two treatment methods on neuronal plasticity. Methods: Therefore, fMRI-paradigms foot tapping and the motor imagery (MI) of a balancing task (tandem walking) were employed. Results: The paradigms investigated were suitable for ataxic stroke patients to monitor changes in neuroplasticity while revealing increased activity in the primary motor cortex (M1) and the cerebellum over 3 months of treatment. Furthermore, analysis of the more complex balance task revealed augmented activation of association areas due to training. Coordination exercises, constituting a specific treatment of ataxic symptoms, indicate more consolidated brain activations, corresponding to a faster motor learning process. Activation within Brodmann Area 7 has been prominent among all paradigms, indicating a special importance of this region for coordinative functions. Conclusions: Further studies are needed to confirm our results in larger patient groups. Clinical Trial Registration: German Clinical Trials Registry (drks.de). Identifier: DRKS00020825. Registered 16.07.2020.
Mitochondrial dysfunction is a pivotal driver in the pathogenesis of acute kidney injury (AKI), chronic kidney disease (CKD), and congenital anomalies of the kidney and urinary tract (CAKUT). The kidneys, second only to the heart in mitochondrial density, rely on oxidative phosphorylation to meet the high ATP demands of solute reabsorption and filtration. Disrupted mitochondrial dynamics, such as excessive fission mediated by Drp1, exacerbate tubular apoptosis and inflammation in AKI models like ischemia–reperfusion injury. In CKD, persistent mitochondrial dysfunction drives oxidative stress, fibrosis, and metabolic reprogramming, with epigenetic mechanisms (DNA methylation, histone modifications, non-coding RNAs) regulating genes critical for mitochondrial homeostasis, such as PMPCB and TFAM. Epigenetic dysregulation also impacts mitochondrial–ER crosstalk, influencing calcium signaling and autophagy in renal pathology. Mitophagy, the selective clearance of damaged mitochondria, plays a dual role in kidney disease. While PINK1/Parkin-mediated mitophagy protects against cisplatin-induced AKI by preventing mitochondrial fragmentation and apoptosis, its dysregulation contributes to fibrosis and CKD progression. For instance, macrophage-specific loss of mitophagy regulators like MFN2 amplifies ROS production and fibrotic responses. Conversely, BNIP3/NIX-dependent mitophagy attenuates contrast-induced AKI by suppressing NLRP3 inflammasome activation. In diabetic nephropathy, impaired mitophagy correlates with declining eGFR and interstitial fibrosis, highlighting its diagnostic and therapeutic potential. Emerging therapeutic strategies target mitochondrial dysfunction through antioxidants (e.g., MitoQ, SS-31), mitophagy inducers (e.g., COPT nanoparticles), and mitochondrial transplantation, which mitigates AKI by restoring bioenergetics and modulating inflammatory pathways. Nanotechnology-enhanced drug delivery systems, such as curcumin-loaded nanoparticles, improve renal targeting and reduce oxidative stress. Epigenetic interventions, including PPAR-α agonists and KLF4 modulators, show promise in reversing metabolic reprogramming and fibrosis. These advances underscore mitochondria as central hubs in renal pathophysiology. Tailored interventions—ranging from Drp1 inhibition to mitochondrial transplantation—hold transformative potential to mitigate kidney injury and improve clinical outcomes. Additionally, dietary interventions and novel regulators such as adenogens are emerging as promising strategies to modulate mitochondrial function and attenuate kidney disease progression. Future research should address the gaps in understanding the role of mitophagy in CAKUT and optimize targeted delivery systems for precision therapies.
Background: The Mini Mental Status Examination (MMSE) and Montreal Cognitive Assessment (MoCA) are the most commonly used scales to detect mild cognitive impairment in population-based epidemiologic studies. The aim of this study was to define which test is more reliable for early diagnosis of vascular dementia – MoCA or MMSE. Material and methodes: This prospective study included 274 patients with acute stroke, both sexes and all age groups. Patients were divided into groups: demented (DP) and non-demented (NDP). Each patient was underwent to a clinical examination and scoring with appropriate scales (MMSE and MoCA). Patients were tested on two times after discharge. Results: Out of the total number of patients, 171 (62.5%) of them were male, and 103 (37.5%) were female (p=0.339). First testing with the MMSE showed that 143 (52%) had mild or moderate dementia. Sixth months after stroke, the number of demented patients increased to 165 (60%). First testing with the MoCA scale showed that 183 (66%) had some degree of dementia, and after the sixth month 191 (69%). The MoCA recorded a greater number of patients with dementia in both, the first and second testing. MoCA is more sensitive than MMSE for detecting patient with vascular dementia 3 and 6 months after stroke (p=0.0004; p=0.01). Conclusion: The MoCA is more sensitive scale than the MMSE for detecting early stages of vascular dementia. It should be used in daily practice more often than the MMSE in order to make a timely diagnosis of the early stage of dementia. Keywords : vascular dementia, MMSE, MoCA
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