The increasingly frequent improper disposal of lithium-ion batteries (LIB) is leading to concerns about the environmental consequences. When they are poured out, the flammable solvents from the electrolytes in LIBs are the threatening soil and plant contamination. If these liquids spill or leak from batteries, they could enter the soil through various pathways and contaminate crops such as cucumber and tomato plants, which have extensive root systems that may facilitate the absorption of ILs. After absorption, some electrolyte components could accumulate inside the plants and have toxic effects, potentially harming plant growth and crop fields. This study investigated how spilling electrolytes with varying combinations of ILs, organic solvents, and lithium salts in different concentrations affects the growth and development of tomatoes and cucumbers. Special attention was paid to examining the influence of electrolyte components on aerial parts and/or fruits of these plants and the levels of metabolites involved in antioxidant protection under stressful conditions, such as malonyldialdehyde (MDA). In this work, certain ILs with bis(trifluoromethylsulfonyl)imide, NTf2, anion have a phytotoxic effect, which negatively affects cucumber and tomato growth and development.
Background: Pancreaticoduodenectomy (PD) known as Whipple procedure is still one of the most complex abdominal surgeries used for treatment of periampullary tumors. PD is often followed with postoperative complications (pancreatic, biliar or intestinal fistula, haemorrhage, intraabdominal abscess, delayed gastric empting. Severe postoperative complications (SPC) can be reason for reoperation and reason of bad outcome of treatment and life treathening condition. Objective: To investigate predicitive value of preoperative hypoalbuminemia for severe postoperative complications (SPC) in patients who have undergone Whipple pancreaticoduodenetomy (PD). However, no similiar study has been ever reported from our country until now. Methods: In this retrospective-prospective study, 100 patients who have had Whipple pancreaticoduodenectomy for malignant periampullary tumors at the Department for Surgery of University Clinic Center Tuzla, Bosnia and Herzegovina were enrolled, from january of 2009 to decembre of 2021. All patients were preoperatively analysed according to serum albumine levels and presensce of hypolabuminemia (serum albumine levels <32g/l). Serum albumine biochemical test were done 1-2 days preoperatively. Clavien Dindo classification was used for determination patients with SPC. Patients who did not have SPC belonged to (I-II) Clavien Dindo group of patients while those who had SPC belonged to( III-V) Clavien Dindo group of patients. Results: Out of 100 patients who have undergone pancreaticoduodenetomy, in 55 (55%) patients postoperative complications were noticed. Mortality rate was 18 (18%) and reoperation has been done in 20 cases (20%). SPC were noticed in 19 patients and most often were: delayed gastric emptying (20%), pancreatic fistula (13%) and intraabdominal collections (9%). Hypoalbuminemic patients had a significantly higher rate of severe postoperative complications ( p<0.05). Using hypoalbuminemia-SPC correlation analaysis, there is confirmed statistically significant correlation between hypoalbuminemia and SPC (ρ= 0.236; p<0.05). Conclusion: Preoperative hypoalbuminemia can be used as predictor and prognostic factor for severe postoperative complications after Whipple pancreaticoduodenectomy. Identification and optimization of serum albumin level prior to Whipple pancreatoduodenectomy may improve surgical outcomes.
Background: A bezoar is a collection of indigestible substances that, after swallowing, form a mass in the gastrointestinal tract, most often in the stomach. A trichobezoar is a mass made of ingested, undigested hairs and food remains, while ingestion of hair is called trichophagia. This is an extremely rare condition, with 90% of cases occurring among women, out of which 80% are under the age of 30. The diagnosis is based on clinical examination, findings obtained through radiological modalities (ultrasound and computed tomography) and endoscopy. Objective: The aim of this article is to present the case of a 17-year-old female patient who visited the doctor due to abdominal pain and a visible mass in the projection of the stomach. Case presentation: The patient, accompanied by her parents, and following the instructions of a general practitioner who suspected the presence of a tumour in the abdomen, reported to the surgical clinic. The US examination revealed the presence of a heteroechoic mass in the stomach area, but it could not be determined with certainty where it belonged (Samsung Medison V8 ultrasound system). The CT scans revealed the presence of an inhomogeneous structure in the stomach area occupying the entire volume of the stomach. The mentioned structure included the presence of internal air particles and marginal imbibition of the orally applied contrast agent. The described structure did not infiltrate the stomach wall and, based on the CT scan, the diagnosis established was a bezoar. Under general anaesthesia, a laparotomy with a gastrotomy was performed, and a hard hook shaped mass composed of hair and remains of undigested food was removed from the stomach. Conclusion: A mobile, palpable mass located in the abdomen of younger female patients accompanied by abdominal symptoms, especially in patients where there is information about hair pulling and swallowing, may suggest trichobezoar. The golden standard for trichobezoar presentation is upper endoscopy. If unavailable, the diagnosis is established by a CT scan, preferably with oral application of a contrast agent. Treatment of larger trichobezoars is surgical, while endoscopic and laparoscopic removal is possible only in the case of small trichobezoars.
Background: Rhinophyma represents an advanced stage of rosacea, chronic cutaneous inflammatory disorder of the pilosebaceous unit with unknown etiology and primarily affects the central face, predominantly the nose region. Significant psychosocial effects are associated with the disease. The diagnosis is made according to the physical exam and pathohistological findings. Rhinophyma occurs more often in middle aged and older male patients. Objective: The aim of this article was to present the cause of rhinophyma, clinical characteristics, surgical treatment and postoperative results. Case report: We present the case of a 60-year-old male patient with rhinophyma, who was successfully treated surgically at the Clinic of Plastic and Reconstructive Surgery. Conclusion: There is no gold standard treatment for rhinophyma. However, surgical treatments, such as scalpel excision, dermabrasion, cryosurgery, argon laser, carbon dioxide laser, and electrocautery, have been used.
Background: Compression of the ulnar nerve at the level of Guyon’s canal is a very rare compressive neuropathy. Due to the vast range of symptoms that can manifest depending on the degree of ulnar nerve compression, the clinical picture is not consistent. Objective: The aim of the study is to outline the diagnostic techniques and therapeutic options. Case report: We reported a case of ganglion cyst-induced compression of the ulnar nerve in Guyon’s canal. A 45-year-old female patient underwent surgical ulnar nerve release in Guyon’s canal at the Clinic for Plastic and Reconstructive Surgery. Discussion: After a thorough medical history and physical examination, the diagnosis of the syndrome is made, and ultrasound and magnetic resonance imaging (MRI) testing are used to determine the origin of the neuropathy. A ganglion cyst was identified pathohistological one month following the surgical excision of the soft tissue tumor. In order to hasten the patient’s nerve recovery, physical therapy was recommended, and the patient was monitored for the following two years. After two years of treatment, the patient has made a very good recovery of the functionally damaged hand, as determined by a modified Bishop scoring method for evaluating functional ulnar nerve recovery. Conclusion: In virtually all cases, early surgical intervention can lead to an outstanding functional recovery. If the symptoms are more severe and continue or get worse for more than three months, early surgical intervention is the gold standard for treating Guyon’s canal syndrome. If soft tissue formations are compressing the ulnar nerve in Guyon’s canal, MRI is thought to be the gold standard for diagnosis.
Background: Psoriasis as an immune-mediated inflammatory skin disease. The basis of the pathogenesis of psoriasis is the dysregulation of immune cell function in genetically predisposed individuals. The characteristic dysfunction of the immune system in patients with psoriasis is manifested as a variation in the cellular phenotypic profile in accordance with the disease status. Objective: The aim of this study was to evaluate the immunophenotypic profile of lymphocytes obtained by flow cytometry as an auxiliary diagnostic tool in the objectivization of the PASI score. Methods: The study group included 40 patients with psoriasis, hospitalized and treated at Dermatology Clinic of Clinical center University of Sarajevo and 30 healthy individuals as controls. After venepunction, the blood samples for determining the immune profile were prepared following standard laboratory procedures using conjugated monoclonal antibodies and BD FACSCanto II flow cytometer. T-lymphocytes (CD3, CD4, CD8), B lymphocytes (CD19), Natural killer cells (NK), and activatet T-cells (CD3HLA) were determined for all patients. Based on the PASI score, the severity and area of the disease was assessed for all psoriasis patients by dermatology specialist. Results: Our data shows no significant difference in any of the lymphocyte subpopulations between psoriasis patients and healthy controls, except CD3HLA. CD3HLA has higher values in patients with psoriasis, p=0.015. Of all the parameters, only NK cells were significantly correlated to the PASI score (rho -0.279; p=0.048). ROC curve analysis revealed a statistically significant difference for the proportion of CD3 lymphocytes (AUC 0.799; p=0.004), CD8 lymphocytes (AUC 0.733; p= 0.023), NK cells (AUC 0.722; p=0.008) and CD3HLA activated T lymphocytes (AUC 0.347; p=0.034). Conclusion: Profile of major lymphocyte subsets in patients with psoriasis is similar to that of healthy controls. The values of CD3, CD8, NK, CD3HLA were defined as biomarkers capable of distinguishing psoriasis according to the severity of the disease. Immunophenotyping of peripheral blood lymphocytes can play an important role as an auxiliary diagnostic method in differentiating the clinical stages of psoriasis and objectifying the PASI score.
High handgrip strength in men’s artistic gymnastics is crucial, mainly for improving performance and to potentially prevent injuries, as well as for the fact that gymnasts body movements are around immovable apparatuses (pommel horse, rings, parallel bars and high bar) for the extended period of time. Since there are not so many studies that have dealt with this topic and on actual competition, we have aimed to examine the handgrip strength influence on the competition result in elite male artistic gymnasts. The sample of participants were conducted of 37 elite male artistic gymnasts (8–21 years old), from 8 different countries as national team competitors at the International Competition “Laza Krstić and Marica Dželatović” held in Novi Sad, Serbia. Basic anthropometric measurements were included (body height, body weight and Body Mass Index (BMI)), along with training experience and handgrip strength measurement (both dominant and nondominant hand). Kolmogorov-Smirnov Z test (p < 0.05) was used for distribution normality, along with regression analysis with Model 1 (participants age, training experience, body height, body weight and BMI), Model 2 (Model 1 + dominant handgrip strength) and Model 3 (Model 1 + nondominant handgrip strength). SPSS v.20 was used for all statistical analysis. Our study have revealed that there is significant influence of all 3 Models on the parallel bars final result (p = 0.33; p = 0.49; p = 0.31, respectively), in terms of all set of variables, whereas body weight Beta scores (28.6%; 30.3%; 32.7%, respectively) moslty explains the results. Both dominant and nondominant handgrip strength are influential factors only on the parallel bars final result. Since both hands are contributing equally, bilateral training is necessary. In order to expand the knowledge on this topic and completely understand the influential factors, future studies are needed on this sample. Regardless of our main findings, our results should be taken with caution.
The main ambition of this paper is to explain and analyze the difficult relations between China and Taiwan and its possible consequences for the regional and international security. The role of the United States is considered as a key actor. It permits to understand the strategies of the different actors due to the strong support given by Washington to Taiwan. The economic relations between the two neighbors are also interesting, to show how the topic is complex and sensitive. Our goal is to propose an analysis mentioning the ambitions of the different sides and their limits due to the realpolitik.
: Artificial Intelligence techniques are widely used for medical purposes nowadays. One of the crucial applications is cancer detection. Due to the sensitivity of such applications, medical workers and patients interacting with the system must get a reliable, transparent, and explainable output. Therefore, this paper examines the interpretability and explainability of the Logistic Regression Model (LRM) for breast cancer detection. We analyze the accuracy and transparency of the LRM model. Additionally, we propose an NLP-based interface with a model interpretability summary and a contrastive explanation for users. Together with textual explanations, we provide a visual aid for medical practitioners to understand the decision-making process better.
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