Background: The clinical course of patients with incomplete reperfusion after thrombectomy, defined as an expanded Thrombolysis in Cerebral Infarction (eTICI) score of 2a–2c, is heterogeneous. Patients showing delayed reperfusion (DR) have good clinical outcomes, almost comparable to patients with ad-hoc TICI3 reperfusion. We aimed to develop and internally validate a model that predicts DR occurrence in order to inform physicians about the likelihood of a benign natural disease progression. Patients and methods: Single-center registry analysis including all consecutive, study-eligible patients admitted between 02/2015 and 12/2021. Preliminary variable selection for the prediction of DR was performed using bootstrapped stepwise backward logistic regression. Interval validation was performed with bootstrapping and the final model was developed using a random forests classification algorithm. Model performance metrics are reported with discrimination, calibration, and clinical decision curves. Primary outcome was concordance statistics as a measure of goodness of fit for the occurrence of DR. Results: A total of 477 patients (48.8% female, mean age 74 years) were included, of whom 279 (58.5%) showed DR on 24 follow-up. The model’s discriminative ability for predicting DR was adequate (C-statistics 0.79 [95% CI: 0.72–0.85]). Variables with strongest association with DR were: atrial fibrillation (aOR 2.06 [95% CI: 1.23–3.49]), Intervention-To-Follow-Up time (aOR 1.06 [95% CI: 1.03–1.10]), eTICI score (aOR 3.49 [95% CI: 2.64–4.73]), and collateral status (aOR 1.33 [95% CI: 1.06–1.68]). At a risk threshold of R = 30%, use of the prediction model could potentially reduce the number of additional attempts in one out of four patients who will have spontaneous DR, without missing any patients who do not show spontaneous DR on follow-up. Conclusions: The model presented here shows fair predictive accuracy for estimating chances of DR after incomplete thrombectomy. This may inform treating physicians on the chances of a favorable natural disease progression if no further reperfusion attempts are made.

Banja Luka is a city which, in October 1969, experienced the strongest earthquake in the territory of Bosnia and Herzegovina. On that occasion 2/3 of the school buildings were severely damaged or destroyed. Banja Luka students were forced to attend that school year throughout the former Yugoslavia. Seismic risk management for schools on the territory of Banja Luka is significant from the aspect of protecting students as a vulnerable category of society. It is also important observing the fact that school facilities are used as facilities for temporary mass accommodation of the affected population during emergencies. Examining the level of earthquake protection, i.e. seismic resilience of the schools in Banja Luka, as a city with a high seismic hazard, implies the resistance of school buildings (material resilience) but also the preparedness of school communities (administration, students and teachers) to react properly in the event of an earthquake (non-material resilience). The results of the research indicate weaknesses in both the material and non-material resilience of schools. The structural aspects of school resilience include the seismic hazard of the area, the soil at school locations in terms of the expected seismic effect, the age and poor maintenance of the buildings, and the undefined ownership of school buildings. Regarding non-structural resistance, a low level of carrying out preventive activities such as education, training and practical exercises for dealing with earthquakes was identified as well as inadequate planning documentation.

: Quality is a key success factor in the market. For the successful performance of a company, it is very important to have high quality and a quality system, and strive for its development and improvement. In this paper, it has been measured the quality of logistics service using the SERVQUAL model in the TC company as one of the most well-known and most used models in the field of quality measurement. The users of the transport service, the respondents, provided certain information on their expectations, as well as their perceptions of the quality of the transport service from the aspect of all five dimensions: reliability, assurance, empathy, tangibles and responsiveness. The SERVQUAL model was chosen to obtain the final results of the quality of service provided to users. The FUCOM method was applied to obtain the final weights of dimensions. The main goal of this paper is to assess the quality of the transport service in the TC company, so that the company has an insight into its current state

Unreinforced unconfined solid brick masonry walls were experimentally tested in full scale (233x241x25cm) and reduced scale (100x100x25cm) at the laboratory of the Institute for materials and structures, Faculty of Civil Engineering in Sarajevo. Cantilever walls were loaded in cyclic shear or pushed monotonically. In order to study the nonlinear behavior in a detailed and global manner, finite element meso- and macro-models of the tested walls were created using the finite element software Diana FEA. Brick units are discretized by continuum elements in a meso-model and discontinuity in displacement field is introduced by interface elements between units. In order to account for brick cracking, an additional interface element was added in the unit middle. Continuum macro-models approximate heterogeneous masonry wall by a single material and discretization is independent of brick layout, i.e., bricks, mortar and unit-mortar interface are smeared out in the continuum. The recently developed engineering masonry model is an orthotropic total-strain continuum model with smeared cracking and it was used with shell elements. Numerical results are verified against the data obtained from the experimental research program. The walls exhibit rocking failure mode in low precompression, while diagonal cracking occurs for higher vertical stresses. The results show good matching with the experimentally obtained curves regarding the ultimate load and ductility.

This paper presents the methodology for seismic analysis of masonry structures that can be employed in commercial software packages such as SAP2000. The concept of elementary block which combines non-linear spring and linear shell elements is used for discretization of masonry walls. The proposed modelling technique with localized nonlinearity can successfully simulate in-plane wall failure modes induced by compressive or tensile axial force and transverse force. It can also be used to investigate out-of-plane collapse which makes it a good candidate for 3D static and dynamic analysis of buildings. The modelling approach is tested on two examples where pushover analysis was performed: a single slender cantilever masonry wall and a family house. The response was verified against the results delivered by 3MURI and MINEA, and reasonable agreement was obtained. It is demonstrated that the transverse walls have significant contribution to the load bearing capacity of buildings.

Determination of dynamic properties of structures is the first step in assessing seismic response, and they can be measured in several ways. Controlling or knowing the input excitation usually applied by impact hammer or vibration shaker, typical for experimental modal analysis (EMA) that has been around for the past few decades, is for majority of structures difficult or practically impossible. Ambient vibration testing (AVT) or operational modal analysis (OMA), on the other hand, is the output-only modal analysis. It does not require knowledge of the input excitation, which is practically induced by wind, traffic or similar random source. In this paper, an investigation of ambient vibrations and numerical modelling of the building of the Institute for Materials and Structures (IMK) of the Faculty of Civil Engineering in Sarajevo was carried out. The main goal was to determine the dynamic characteristics of the IMK building using the DIGITEX SENTRY system and Artemis modal software. In addition to testing the IMK building, testing of simpler systems such as a wooden simple beam and a steel cantilever was also conducted. For each experiment, a modal analysis was performed in the Tower 8 software package. The numerical model of the building was more flexible than measured in the experiments, and the results were only comparable after inclusion of partition walls in the analysis.

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Extracts obtained from plant material have widely applied in the chemical and pharmaceutical industries because they contain significant concentrations of biologically active substances. Commercial daisy extract (Bellis perennis) was used in this paper for in vitro testing of tyrosinase enzyme inhibition, and antioxidant and antimicrobial activity. Inhibition of the tyrosinase enzyme was determined by monitoring dopachrome formation at a wavelength of 492 nm. Antioxidant activity was tested using FRAP and DPPH methods, while antibacterial activity was tested by diffusion technique on reference strains from the ATCC collection. The results showed that daisy extract inhibits tyrosinase enzyme in a dose-dependent manner. The extract effectively neutralized DPPH radicals and also showed good reducing ability. Bacterial strains used for in vitro antimicrobial activity testing did not show sensitivity to the extract concentrations used in this study.

Due to climate extremes and limited natural resources, especially water, we can expect increased demand in the future for species that can better tolerate climate extremes such as drought. One potentially valuable horticultural species is the endemic species of the Dinaride Mountains Micromeria croatica (Pers.) Schott (family Lamiaceae). It grows in the crevices of carbonate rocks, extending from an altitude of 150 m to more than 2000 m. This study aims to provide additional insight into the genetic and morphological diversity of this endemic species, focusing on valuable horticultural traits. To achieve this goal, morphological and molecular analyses were performed on ten natural populations. Through STRUCTURE and PCoA analyses, ten M. croatica populations were placed into western and eastern genetic groups, with several individuals from western populations assigned to the eastern group and vice versa. These atypical individuals assigned to the new genetic group by BAPS analysis indicate gene flow between western and eastern populations. Similarly, an analysis of molecular variance revealed fewer genetic differences than within studied populations. Both PCA and CANDISC analysis based on eleven morphological traits largely confirmed the existence of two slightly different genetic groups. Two populations containing plants with the most flowers per shoot, one with white-flowered individuals, one with the roundest leaves, and one with the narrowest leaves proved to be the most horticulturally valuable. The genetic and morphological variability found should be a sufficient basis for the potential selection of M. croatica populations and individuals for horticultural purposes.

Cilj rada usmjeren je pregledu i analizi kritika upućenih konceptu cjeloživotnog obrazovanja razvijenog u okrilju UNESCO-a, a odnosi se na njegovu prvu razvojnu fazu tijekom 1970-ih godina. Radom na dokumentaciji izdvojene su kritike koje su se prvenstveno odnosile na teorijska promišljanja o konceptu i iz kojeg do izražaja dolaze obilježja kao što su (ne)jasna definicija cjeloživotnog obrazovanja, uključivanje neintencionalnih oblika učenja, uloga nastavnika u ostvarivanju koncepta i sl. Pregled kritika koncepta temelji se ponajprije na stajalištima predstavnika radikalne kritike, potom i na kritikama pripadnika analitičke filozofije odgoja i obrazovanja. Posljedično se iznose odgovori na iskazane kritike, a koje su dali zagovornici koncepta cjeloživotnog obrazovanja. U svrhu postizanja što objektivnijeg pregleda i analize kritika izdvojene su i kritike koncepta cjeloživotnog obrazovanja autora, koji su ujedno bili i njegovi zagovornici. Radikalna stajališta o ostvarenju cjeloživotnog obrazovanja unutar okvira sustava, kao i tvrdnje predstavnika filozofije odgoja i obrazovanja o proizvoljnom definiranju i shvaćanju koncepta, potaknula su daljnja propitivanja o razradi koncepta kako bi se u odgojno-obrazovnom diskursu postigla što viša razina suglasnosti i zajedničko razumijevanje ciljeva, a posljedično i smjer djelovanja u svrhu njegove implementacije. To nije moguće bez uvažavanja postojećih obilježja nacionalnih sustava odgoja i obrazovanja kojima bi krajnji cilj trebao biti stvaranje pretpostavki za odgovaranje na obrazovne potrebe svakog pojedinca, što je zapravo odraz humanističkog podrijetla koncepta.

Plant extracts are increasingly being examined in the corrosion inhibition of metal and alloys in various environments due to their potent antioxidant properties. The use of Artemisia annua L. aqueous extract (AAE) as an aluminium alloy 5083 (ALA) corrosion inhibitor in artificial seawater (ASW) was investigated using electrochemical tests and spectroscopy tools, while the active biocompounds found in AAE were analyzed using high-performance liquid chromatography (HPLC). Electrochemical results showed that AAE acts as an anodic inhibitor through the physisorption (ΔG ≈ –16.33 kJ mol−1) of extract molecules on the ALA surface, thus reducing the active sites for the dissolution of the alloy in ASW. Fourier-transform infrared spectra confirmed that phenolic acids found in AAE formed the surface layer that protects ALA against the corrosive marine environment, while HPLC analysis confirmed that the main phytoconstituents of AAE were chlorogenic acid and caffeic acid. The inhibition action of phenolic acids and their derivatives found in the AAE was based on the physisorption of caffeic acid on the ALA surface, which improved physicochemical properties of the barrier film and/or conversion of Al3+ to elemental aluminium by phenolic acids as reducens, which slowed down the diffusion rate of Al3+ to or from the ALA surfaces. The protective effect of the surface layer formed in the presence of AAE against ASW was also confirmed by inductively coupled plasma–optical emission spectrometry (ICP-OES) whereby the measured concentration of Al ions after 1 h of immersion of ALA in the pure ASW was 15.30 μg L−1 cm−2, while after the addition of 1 g L−1 AAE, the concentration was 3.09 μg L−1 cm−2.

Introduction: The health system is one of the most complex systems in any country. According to the definition of the World Health Organization, the health caresystem includes health infrastructure that provides a spectrum of programs and services and provides health care to individuals, families and the community. A basichuman right is the right to health care, which includes health activities such as preventive, curative and palliative treatment. The organization of palliative medicineis necessary at all levels of health care.Aims: Situational analysis of the organization of palliative care in the Clinical Center of the University of Sarajevo. Examining the knowledge and approach of healthcareworkers in the process of providing palliative care at the Clinical Center of the University of Sarajevo. To examine the attitude of healthcare workers towards theAwareness and attitudes of nurses of the Clinical center of the University ofSarajevo (ccus) towards the organization of palliative care way palliative care is organized in the Clinical Center of the University of Sarajevo.Material and methods: 141 subjects employed at the Clinical Center of the University of Sarajevo (CCUS) participated in the research. The research is descriptiveand analytical. The results are presented in tables and graphs, chi-square and Fisher’s exact test were used for testing the significance of differences.Results: It was found that there are different knowledge, attitudes and approaches of the respondents regarding the way palliative care is organized, the provision ofservices and treatment in the hospital. The majority of respondents (64%) believe that palliative care should be organized in institutions for palliative care that meetthe conditions of the prescribed standards and criteria for palliative care.Conclusion: Significant differences were found in the knowledge, practice and attitudes of health workers about palliative care.

Introduction: Conflicts are a social phenomenon and occur in all organizations where people work. So, they are inevitable even among nurses, because the work they do is very responsible and stressful. Conflicts of a personal nature are not uncommon, and they are produced by intimacy in the workplace.Methodology: The study was conducted among 146 nurses employed at the Clinical Center of the University of Sarajevo. The study is descriptive, analytical andcomparative. The original author’s questionnaire created on the basis of professional and scientific literature was used as a study instrument. The goal of thestudyisto determine if the conflict situations in nursing clinical practice are related to the dissatisfaction of nurses with working conditions, lack of motivational techniques, poor communication in the team and superior-subordinate relations.Results: Most respondents state that conflict situations are short-lived and do not affect work. Respondents pointed out that the most commoncauses of conflict are poorcommunicationand personal contempt of colleagues (71 or 48.6%), violations of labor regulations and non-performance of work obligations (68 or 46.6%), differences in education (39 or 26.7%), etc. The most common manner that nurses use to resolve conflicts is to exchange information in order to reach a joint decision, to negotiate and seek compromises.Conclusions: Conflicts are manifested in the form of negative emotions, so in this regard, they can have significant negative consequences, and contribute less toimprovement or have a positive effect on the work environment. Communication conflicts between nurses are detrimental to teamwork - negative confrontation between two sides, often revealing anger, not talking for a longer period, or personally standing out at the expense of the other side.