Horseshoe lung is a rare congenital pulmonary anomaly in which the caudal and basal segments of the left and right lungs are joined together behind the pericardium at the height of cardiac apex. Most patients with horseshoe lung have many other cardiovascular anomalies typical of the scimitar syndrome or the hypogenetic right lung syndrome. We report on a patient with horseshoe lung not associated with scimitar syndrome, but presented with a focal diaphragmatic herniation of the liver, such as never reported before in case of horseshoe lung without associated scimitar syndrome.

Light-weight and environmentally friendly materials with good mechanical properties are much appreciated in various modern applications. Weight reduction can improve the performance of many components while reducing the fuel consumption of vehicles. Magnesium is one of the most popular weight-reducing materials because of its low density, good mechanical properties, large natural reserves and good machining properties. The strength, stiffness and favourable metallographic structure of products can be improved by a forging process in which components are shaped from feedstock slugs by applying compressive force through various forging dies. However, widespread usage of forging technology in industrial practice is very rare in comparison to casting, due to the specific deformation characteristics of magnesium having a hexagonal close packed basal crystal structure. This paper deals with the determination of the influence of the most important process parameters on the deformation process of magnesium alloys. On the basis of extensive experimental study, anisotropic flow and the impact of the most important input process factors on the plastic deformation of AZ80 wrought alloy are considered. The results presented in this paper are directly related to industrial practice and have significant potential as a case study for the further development of FEM models capable of predicting anisotropic material flow during applied plastic deformation. The studies presented in the paper also make possible defining recommended technological parameters of the forging process.

Starting from methyl salicylate and 2-amino-2-(hydroxymethyl)propane-1,3-diol 1a , or 2-amino- 2-methylpropane-1-ol 1b , the 2-oxazoline derivatives 2a , 2b or 3, as well as mono- 4a and 4b and bis- 5a and 5b derivatives of salicylic acid were synthesized. Reactions were performed by microwave irradiation in the presence of tetrabutylammonium bromide or metallic sodium as catalyst, as well as by conventional heating. Microwave-induced reaction of some diols, diamines and amino alcohols with methyl salicylate gave mono- and/or bis- derivatives of salicylic acid 4c, 5c, 5d, 6c, 8c, 7a, 7b, 8a and 8b . The mono- and bis-salicyloyl derivatives 4c , 5c and 5d were transformed to the corresponding phenyl-azo derivatives 9, 10c and 10d . The structure of compound 3 was proved by the X-ray analysis and the R-configuration on its stereocenter was confirmed. The antioxidant and cytotoxic activities of the synthesized derivatives were evaluated in a series of in vitro tests. Compounds 5d , 8b and 8c exhibited very strong activity against hydroxyl radical. Six 4c , 5d , 8a-c , 10c of 16 tested compounds inhibited growth of MDA-MB-231 cells at a nanomolar concentration. Compounds 8c and 10c showed high cytotoxicity against MCF7 cells, whereas compounds 4c , 5d , 8a-c and 10d showed high activity against K562 cells.