Background: The SCORAD index is most often used to assess the severity of atopic dermatitis (AD). Hypersensitivity to food allergens is found in up to 60% of children with moderate to severe forms of the disorder and it is a significant cause of intensification of skin changes. Aim: The study was to assess the severity of AD and the presence of hypersensitivity to food allergen. Methods: The study comprised 114 children (56 boys and 58 girls) aged from 1.5 months to 14.9 years, with diagnosed AD according to Hanifin and Rajka’s criteria. The severity of the illness was assessed by the SCORAD index and the following were analysed to recognize hypersensitivity to food allergens: anamnesis data, total IgE antibodies, specific IgE antibodies and the results of the skin prick test (SPT) for food allergens. Results: 61.4% of children had a moderate form of the illness, the median SCORAD index was 28.5 points. There was a significant correlation with the total SCORAD index values for: spread (p< 0.0001), intensity (p<0.0001) and subjective signs (p<0.0001), as well as a correlation between the parameters: spread and intensity of changes (p < 0.0001); spread and subjective signs (p< 0.0001); intensity and subjective signs (p < 0.0001). Hypersensitivity to food allergens was found in 28% of children tested (history of hypersensitivity to food 47.5%, high total IgE antibodies 56.1%, SPT positive 32.4%, specific IgE antibodies to food allergens 28%), and the most frequent allergens responsible were cow’s milk, 12.3% and eggs in 5.3% children. Conclusion: The most common was the moderate form of illness, and hypersensitivity to food allergens was significantly present. By removal of the responsible allergen, we can contribute to a reduction in the intensity of changes.
Introduction: Rehabilitation of patients after the stroke is very demanding and complex process, because in addition to damage of motor functions, the patients suffer from the range of other dysfunctions and complications. Timely and early initiation of rehabilitation treatment can reduce the degree of disability; it can result in increased mobility, independent functioning and shorter period of hospitalization. Aim: of this study was to determine the outcome of early rehabilitation treatment of patients suffering from ischemic and hemorrhagic stroke, in relation to their age, sex, degree of disability, and activities of daily living. Subjects and methods: This was a prospective study, which included 50 patients suffering from ischemic stroke and 50 patients suffering from hemorrhagic stroke. All patients were tested on admission and discharge from the hospital. Age and sex of the patients was analyzed, in addition to Rankin scale, used for evaluation of functional disability, and Barthel index used for evaluation of activities of daily living. Results and discussion: The outcome of early rehabilitation treatment was negatively influenced by the older age of patients (p=0.03). Males showed significantly better functional recovery from females (p=0.03). The values of Rankin scale and Barthel index showed significant recovery in all patients on discharge ((p< 0.001), however, these values were statistically more significant in patients with hemorrhagic stroke (Rankin scale p=0.03; Barthel index p=0.04). Conclusion: Older age of patients negatively affects the outcome of early rehabilitation treatment. Male stroke patients showed better results of early rehabilitation treatment. The degree of disability is significantly reduced, while the degree of activity of daily living is significantly improved with the early rehabilitation treatment. However, this was more prominent in patients suffering from hemorrhagic stroke.
Breast cancer is the most common cancer among women. To date, 22 common breast cancer susceptibility loci have been identified accounting for ∼8% of the heritability of the disease. We attempted to replicate 72 promising associations from two independent genome-wide association studies (GWAS) in ∼70,000 cases and ∼68,000 controls from 41 case-control studies and 9 breast cancer GWAS. We identified three new breast cancer risk loci at 12p11 (rs10771399; P = 2.7 × 10−35), 12q24 (rs1292011; P = 4.3 × 10−19) and 21q21 (rs2823093; P = 1.1 × 10−12). rs10771399 was associated with similar relative risks for both estrogen receptor (ER)-negative and ER-positive breast cancer, whereas the other two loci were associated only with ER-positive disease. Two of the loci lie in regions that contain strong plausible candidate genes: PTHLH (12p11) has a crucial role in mammary gland development and the establishment of bone metastasis in breast cancer, and NRIP1 (21q21) encodes an ER cofactor and has a role in the regulation of breast cancer cell growth.
Enkorten is a new potential drug for the treatment of rheumatoid arthritis, with an immunomodulatory and anti-inflammatory effect. It is a combination of two peptide components of endogenous origin: methionine-enkephalin of 5 mg and tridecactide of 1 mg (Picture 1 and 2). According to the chemical structures, these components correspond to amino acid sequences of the neuropeptide precursor proopiomelanocortin.
The article sheds light on the status of arts science in the context of its development at the University of arts in Belgrade in the last fourty or so years. It points out the current questions on classification of scientific fields and scientific areas, the relations of scientific and artistic education, as well as theory and practice, and the interrelations of individual disciplines. It presents the contributions to the deliberation of the key matters of classification and definition of arts science, especially the works of Milan Damnjanović and Miško Šuvaković.
The establishment of inalienable Muslim endowments (pl. awqaf; sing. waqf) in Bosnia and Herzegovina goes back to the days of the Ottoman occupation of the region in 1463. This article explains their establishment and development together with their institutions with reference to the fifteenth and sixteenth centuries when some of the most famous awqaf emerged. The great period for awqaf came to an end with the Austria-Hungarian takeover in 1878. The author argues that since then the institution of waqf in Bosnia and Herzegovina was subject to injustice, hostility, and devastation from the various regimes that have ruled the country. He explains the deteriorating position of waqf property through the periods of the Kingdom of Yugoslavia and the unlawful confiscation and nationalisation of waqf property and the ultimate complete abolition of the institution of waqf under the communist and socialist regime. This situation lasted until the independence of Bosnia and Herzegovina in 1992 when the Council of the Islamic Community of Bosnia and Herzegovina established the Waqf Directorate. The author also evaluates the legal applications of the restitution claims made by religious communities for the property which was unlawfully confiscated through various legislative mechanisms during and after the communist regime. The ways to safeguard and protect waqf property will be examined as well.
This paper deals with the emergence and development of feminism in general and feminist psychology with special emphasis on feminist's reaction to traditional assumptions in Freudian psychology and male dominated theory and research. Feminist movement simply started as a women's activism which later claimed political identity and finally ended as women's liberation movement. Feminists simply advocate gender equality. Emergence of feminist psychology movement and appearance of significant female figures in psychology is further explained along with their contribution to the theory, personality and specific developmental issues along with its input to the therapy and counseling field. The influence of four feminist philosophical approaches namely, liberal feminism, cultural feminism, radical feminism and social feminism are also shortly discussed alongside with their practical implications. Above and beyond, feminist contribution to the therapy field reflected in offering specific therapy goals are also discussed. Self esteem as a core issue and one of feminist therapy goals is finally discussed and presented through a specific case study illustration. Feminist therapy is important therapy approach with significant therapy goals contribution in relation to women's mental health issues. Consideration of sex, gender, cultural diversity, etiology, diagnosis and treatment is feminist request for successful therapy because fixing woman for functioning in a dysfunctional society seems not enough.
Very often conflict and post-conflict images of Bosnia-Herzegovina overshadow noteworthy developments and changes. Similarly the role and contributions of women's NGOs in the process of civil society building don't receive proper publicity and acknowledgment. Therefore, this paper aims to put in the perspective women's NGOs in Bosnia-Herzegovina by providing historical and theoretical analysis of their contributions towards peace-building and elections, state-building and civil society building. Furthermore, this paper aims to analyze origin and developments of gender legal, economic and socio-political framework as such framework is the precondition for actual application and achievement of gender equality. Finally, this paper applies theoretical framework of civil society functions on leading women's NGOs. The author uses ethnographic methodology, written sources, NGO and governmental reports and gender related laws. The results of this paper indicate that women's NGO's in Bosnia-Herzegovina made significant progress from providing mere humanitarian services to the establishment of gender institutional, legal, economic and socio-political framework. Such progress placed women's NGOs at the position of application and achievement of gender equality in Bosnia-Herzegovina. With regards to the fulfillment of civil society functions, results indicate that women's NGO's made significant achievements in advocating values of human rights, tolerance and understanding, offering civic training, promoting civic education and public issues through media, and promotion of conflict resolution and inter-faith dialogue. However, civil society functions such as control of political power, monitoring of political participation and elections and promoting of anti-corruption awareness don't indicate significant involvement of women's NGOs.
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