The concept of decision making is considered as one of the key topics in the field of strategic management and related fields. According previous theoretical considerations and discussions of the main contributors, there is no single routine/path used by managers in strategic decision-making. Mintzberg, Raisinghani and Théorêt define strategic decisions with regard to the decision-making level as a combination of entrepreneurial activities and efficient use of resources. The process of making strategic decisions is often described as unstructured, non-routine associated with uncertainty, defining it as a set of activities, which includes the collection of information, the development of alternatives and their evaluation, and ultimately the selection of the best alternative. It is clear, therefore, that it is difficult to talk about strategic decision-making exclusively in the context of a logical sequence of activities by division makers. This type of presentation of strategic decision-making, based on the idea of rational action by top management, as the strategic management executives, is also shown in numerous management text books. In their editorial in a special issue of the prestigious Strategic Management Journal, Cyert and Williams synthesized the conclusions of the special issue contributors. Analysing the cause-and-effect relationship between strategy, strategic decision-making and the organization, emphasis is put on the importance of organizational learning. In the conditions of creating an economy based on information and knowledge, a connection is created between information, organizational structure and strategic decision-making. In complex systems, such as companies, one of the key problems that occurs when making decisions is to find out where the decision comes from and how it is realized. Strategic decisions are most often a collection of some individual decisions in the organization or a consequence of informal conversations or actions that lead to collective action. The focus of this paper is an attempt to identified a key theoretical underpinning, through an overview of relevant theories and strategic management schools. In so doing, this paper will use the concept of strategic management schools, presented by Mintzberg, Ahlstrand and Lampel in their popular book Strategic Safari.
Regardless of the geopolitical and economic challenges the world as well as the European Union (EU) face, it appears that these issues have not, in the slightest, affected the EU's commitment to the green transition. The European Commission continues to provide strong support to member countries in implementing reforms that encourage the green transition. In conditions of sluggish economic growth, the investments in the green transition are characterized as a significant driver of economic growth. This paper analyzes and evaluates the implications of the EU's green transformation on the economic development of the Western Balkans (WB), with a special focus on the Green Deal and climate neutrality. The Green Deal represents the EU's key strategy for achieving climate goals and transitioning to a sustainable, green economy. Through an analytical approach, the impacts of the green transformation and related policies on the economic, social, and environmental aspects of the region are explored, considering the global Green Economy Index. The research methodology includes cluster analysis and analysis of the green economy index to assess the correlation between factors of the green economy and economic development, considering financial, institutional, and legal aspects of the Green Deal. Additionally, a comparison of development according to the Green Economy Index is applied to identify the position, potential, but also limitations of the Western Balkans in this context. Key indicators of the green economy, such as investments in renewable energy sources, energy efficiency, and sustainable infrastructure, are analyzed in terms of their impact on macroeconomic indicators such as gross domestic product per capita, unemployment, etc., in the Western Balkans. The paper identifies a range of opportunities for economic development, including increasing investments in renewable energy sources and developing sustainable infrastructure projects, but at the same time recognizes limitations, such as a lack of capacity, financial resources and public sector support to implement sustainable policies. Furthermore, there is a risk of increasing economic and social inequalities in the process of green transformation, as well as potential negative environmental consequences if appropriate measures are not taken.
Background: Benign acute childhood myositis (BACM) is a rare complication of viral URTIs, usually occurring in winter. It is characterized by acute onset of bilateral calf pain and difficulty/refusal to walk. A prodromal phase precedes these manifestations, consisting of catarrhal and constitutional symptoms. These are associated with increased muscle-specific enzymes, usually normal inflammatory parameters, and leukopenia. Objective: Our study aimed to define the demographic, clinical, and laboratory characteristics of BACM patients and determine the etiology leading to their development. Methods: Medical charts for patients diagnosed with BACM from October to April 2023/2024 at the Pediatric Clinic Clinical Center University of Sarajevo, Department of Allergology, Rheumatology, and Immunology were reviewed retrospectively. Relevant medical information was collected for 20 patients. Statistical analysis was done in Microsoft Excel 2013. Results: Demographic analysis demonstrated male predominance (75%), with primarily school-aged children affected (median age 8.36). Most cases occurred in winter (60%). The majority of patients presented with bilateral calf pain (100%), difficulty walking (90%), and fever (100%). All cases demonstrated increased CK levels, with median values of 3779 U/L; a notable number had leukopenia (70%). The most commonly isolated pathogen was Influenza B virus (75%). Conclusion: BACM is relatively rare but presents acutely and leads to plenty of distress for both patients and their parents. A child with coryzal symptoms complicated by bilateral calf pain or difficulty/refusal to walk and an increase in CK levels should raise suspicion of BACM. The condition is self-limiting and usually resolves without complications.
BACKGROUND Non-ST segment elevation myocardial infarction (NSTEMI) poses significant challenges in clinical management due to its diverse outcomes. Understanding the prognostic role of hematological parameters and derived ratios in NSTEMI patients could aid in risk stratification and improve patient care. AIM To evaluate the predictive value of hemogram-derived ratios for major adverse cardiovascular events (MACE) in NSTEMI patients, potentially improving clinical outcomes. METHODS A prospective, observational cohort study was conducted in 2021 at the Internal Medicine Clinic of the University Hospital in Tuzla, Bosnia and Herzegovina. The study included 170 patients with NSTEMI, who were divided into a group with MACE and a control group without MACE. Furthermore, the MACE group was subdivided into lethal and non-lethal groups for prognostic analysis. Alongside hematological parameters, an additional 13 hematological-derived ratios (HDRs) were monitored, and their prognostic role was investigated. RESULTS Hematological parameters did not significantly differ between non-ST segment elevation myocardial infarction (NSTEMI) patients with MACE and a control group at T1 and T2. However, significant disparities emerged in HDRs among NSTEMI patients with lethal and non-lethal outcomes post-MACE. Notably, neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) were elevated in lethal outcomes. Furthermore, C-reactive protein-to-lymphocyte ratio (CRP/Ly) at T1 (> 4.737) demonstrated predictive value [odds ratio (OR): 3.690, P = 0.024]. Both NLR at T1 (> 4.076) and T2 (> 4.667) emerged as significant predictors, with NLR at T2 exhibiting the highest diagnostic performance, as indicated by an area under the curve of 0.811 (95%CI: 0.727-0.859) and OR of 4.915 (95%CI: 1.917-12.602, P = 0.001), emphasizing its important role as a prognostic marker. CONCLUSION This study highlights the significant prognostic value of hemogram-derived indexes in predicting MACE among NSTEMI patients. During follow-up, NLR, PLR, and CRP/Ly offer important insights into the inflammatory processes underlying cardiovascular events.
Change in cytoarchitecture and reconnection of neurons in rats' brain under direct two months high frequency electromagnetic field (HFEMF) exposure has been found, supported with data and discussed. HFEMF used in the experiment had the following characteristics: 2.0 GHz frequency, 0.015 A/m intensity, electric field strength of 5.64 V/m, and SAR value was 2.5 W/kg. Rats were exposed for 6 hours a day for 6 days a week, during period of 60 days with experimental HFEMF. Six months after the treatment, histological and unbiased stereological analyses show that there is a reconnection of neurons in rats' brain, demonstrated by slight increase in their number and production of new dendrites. Effects of HFEMF on neuronal disconnection were detected via caspase, while the SNXS25 protein indicated their reconnection and regeneration. Immunohistochemical analysis of nervous tissue in this paper shows that HFEMF disrupt the work of proteins found on cell membranes and endocytic function of neurons and thus interrupts interneuron communication. The advantage of HFEMF over other methods of treating brain damage is in their controlled and very precise use, with specifically defined characteristics of HFEMF, without ionizing and mutagenic effect on neurons.
Forgone healthcare is a hot topic in the United States. One reason is that many Americans cannot afford healthcare or health insurance. This article examines whether there are statistically significant differences in cancer mortality between US states with low, medium, and high levels of forgone healthcare. The analysis revealed statistically significant differences in cancer mortality rates between US states. Evidence shows that the percentage of adults unable to access healthcare when needed due to cost, and the percentage of adults reporting fair or poor health, are associated with differences in cancer mortality rates. These findings have important policy implications, highlighting the need for state-specific measures to improve the health and wellbeing of the population.
Cancer is one of the leading causes of death, which emphasises the need for prevention, detection and treatment. This article aims to investigate whether there are statistically significant differences in gender-specific cancer incidence and mortality between countries with low, medium and high health expenditure (as a percentage of GDP). The results for the year 2022 indicate statistically significant differences in cancer incidence and mortality in men between countries with low and medium health expenditure and countries with low and high health expenditure; however, no such differences were found in women.
Artificial intelligence is rapidly transforming higher education, continually oscillating between its innovative potential and concerns over academic integrity. While universities are expected to develop policies addressing ethical and pedagogical challenges, many institutions have yet to implement clear guidelines. To extract the dimensions of students’ perceptions of generative AI, the authors primarily used exploratory factor analysis. By using the exploratory factor analysis three key dimensions were revealed, i.e. 1) awareness and familiarity with AI tools, shaped both by personal exposure and institutional practices 2) institutional engagement and guidance, emphasizing the degree to which professors integrate AI in teaching and the demand for clearer instructions on its use and 3) concerns ranging from perceived risks of misuse and violations of academic integrity to recognition of AI’s educational value. These findings imply the urgent need for universities to establish transparent AI policies and provide guidance, ensuring that students can engage with AI tools ethically and effectively.
Background: As for the development of pharmacy in medieval Bosnia it was largely conditioned by the specific position of Bosnia and Herzegovina (B & H) during the period when Bosnia was a part of Ottoman Empire from 1463 until 1878, and later was ocupied by Austro-Hungarian Empire from 1878 until 1918. Objective: The topic of this paper is the development of pharmacy in the Middle Ages, while the aim of this article is to introduce readers to the development and importance of pharmacy and health care activities in general in this century. Methods: For preparing this article authors used, as main source, published books, monographs and papers deposited in indexed databases: PubMed Central, Scopus, Hinari, EBSCO, etc., especially documents that speak and testify about health and hygiene data and conditions in B & H from the Middle Ages and the time of the independent Bosnian state. Because, very little was written down and knowledge was mainly transmitted orally. Results and Discussion: Bosnia, as an independent country, was first mentioned in the Charter of the Kulin Ban in the 12th century. The charter was addressed to the Dubrovnik Republic and it ensured safe passage for merchants through Bosnia and exemption from taxes. The Dubrovnik Republic also had a lot of influence on the development of all social conditions, including medicine and pharmacy. Doctors and pharmacists could come to Bosnia without hindrance and engage in treatment and the sale of medicines, without having to fear whether they would pay taxes to the state or be robbed. In the Medieval Bosnia there are used various ljekarusas (medicine books): Muslim, Jewish, Serbian, Croatian/Franciscan. Unfortunately, many of these manuscripts were destroyed or is lost track of them. Some perished in the wars in 1914, 1941 and 1992. The incineration of the Oriental Institute and the National and University Library, Gazi Husrev-bey Library, the Monastery Plehan, Petricevac, Jajce, Guca Gora, Fojnica, Kresevo, etc. Most of them are preserved in the Franciscan monasteries and, also, the previously transcribed of ljekarusa in oriental languages like was Dervis Nidaija (Bedrudin Muhammad bin Muhammad Ibn Derivis ‘Quasumi). There were about 30 copies of his works „Menafiun us Tibbi Nida“ - for the benefit of the people Nidaija book - which were transcribed from the 1557 to 1839. There are several copies of the works of Alauddin Ibn Nafis (Ali ibn Abi l-Hazm al-Qarshi Ibn al-Nafis), followed by Abdullah Ibn Sina - Avicenna (Abu Ali al-Husain Ibn Abd-Allah Ibn Sina), Rhazes (Abu Bakr Muhammad bin Zakariyya ar-Razi) and other Arab authors. Some of theme were translated by Hamdija Karamehmedovic and Sakir Sikiric, which kept at Library of Hygiene and Public Health Institution in Sarajevo. These manuscripts were accessible mainly to intellectuals and people from the wealthy ruling circles until Bosnia fellt under the influence of the Ottomans, medical treatment in Bosnia was quite primitive, the number of pharmacies and health institutions was minimal, and hygienic conditions were quite poor. Conclusion: In the Medieval Bosnia the most important was practicing of traditional medicine based of used of experiences from the arabic literature which dominated almost 6 century in medieval Bosnia and spells were mainly practiced, which were passed down from generation to generation, and also in the Medieval Bosnia there are used various ljekarusas: Muslim, Jewish, Serbian, Croatian/Franciscan, by word of mouth. It was only with the arrival of the Ottomans that Vakuf\'s hospitals (Hastahanas in Sarajevo, Tuzla, Mostar, Travnik and Banja Luka) and pharmacies began to open, and the health system was better organized.
Fine-grained structural steel of the S690QL designation is widely used due to its very good mechanical properties and good weldability and bending, resistance to abrasion and corrosion. It is most often made in the form of plates of different thicknesses. S690QL steel plate has excellent performance characteristics and is used when low temperature resistance and important strength components are required. It is used in addition to applications for construction machines and structures, mining machines and in the energy sector, highways, railway bridges, etc. Since this steel is used in very demanding conditions such as low temperature, it is very important to test the mechanical properties of the impact toughness at these temperatures. Toughness is an important property that can indicate a material's tendency towards brittle fracture. In this work, a large number of samples were tested for this property, i.e. impact toughness at a temperature of -40°C taken from plates of different thicknesses made of S690QL steel. In addition to this property, the grain size of this steel after heat treatment is also taken into account. These characteristics and their mutual dependence provide directions for correcting the production of semi-finished products or finished products.
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