Coordinate measuring machines (CMMs) are widely used to check dimensions of manufactured parts, especially in the automotive industry. The major obstacles in automation of these measurements are fixturing and clamping assemblies, which are required in order to position the measured object within the CMM. This paper describes how an industrial robot can be used to manipulate the measured object within the CMM work space, in order to enable automation of complex geometry measurement.
Human cytomegalovirus (HCMV) forms two gH/gL glycoprotein complexes, gH/gL/gO and gH/gL/pUL(128,130,131A), which determine the tropism, the entry pathways and the mode of spread of the virus. For murine cytomegalovirus (MCMV), which serves as a model for HCMV, a gH/gL/gO complex functionally homologous to the HCMV gH/gL/gO complex has been described. Knock-out of MCMV gO does impair, but not abolish, virus spread indicating that also MCMV might form an alternative gH/gL complex. Here, we show that the MCMV CC chemokine MCK-2 forms a complex with the glycoprotein gH, a complex which is incorporated into the virion. We could additionally show that mutants lacking both, gO and MCK-2 are not able to produce infectious virus. Trans-complementation of these double mutants with either gO or MCK-2 showed that both proteins can promote infection of host cells, although through different entry pathways. MCK-2 has been extensively studied in vivo by others. It has been shown to be involved in attracting cells for virus dissemination and in regulating antiviral host responses. We now show that MCK-2, by forming a complex with gH, strongly promotes infection of macrophages in vitro and in vivo. Thus, MCK-2 may play a dual role in MCMV infection, as a chemokine regulating the host response and attracting specific target cells and as part of a glycoprotein complex promoting entry into cells crucial for virus dissemination.
In distribution system, the subject of fault location has been of considerable interest for a long time. The objective of this paper is to develop Cumulative approach for fault location based on statuses of Fault Indicators (FI), Circuit Breakers (CB), Fuses and Fault Impedances from distance protection devices. This approach is using mainly graph theory algorithms and Area Marking Strategy to resolve fault diagnosis problem in electric power networks. Unlike neighborhood approach where one link only affects the marking of neighbor areas, cumulative approach marks all areas down the link. In many situations, cumulative approach may outperform neighbor approach.
This paper presents the discrete-event simulator of the low-voltage broadband power line communication (BPLC) access network in accordance with the IEEE P1901 standard. The proposed simulator enables the cross-layer simulation of the physical (PHY) and medium access control (MAC) layer. The performance of the digital communication techniques at the physical layer and the characteristics of the shared medium are integrated at the MAC layer through the probability of the bit error. The proposed simulator was applied in order to estimate the throughput in the simple BPLC network. For the selected set of parameters at the MAC and PHY layer in the test network, the simulator recorded average download throughput of 900kbps, registration time of 36ms and packet delivery ratio of for 0.98 between each station and the HE. DOI: http://dx.doi.org/10.5755/j01.eee.19.5.1440
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