Aim: The main goal of this research is to correlate anthropometric characteristics of newborns in pregnant women who consume cigarettes during pregnancy. The study was conducted at the Obstetrics Clinic of the Clinical Center, University of Sarajevo. Methods: The retrospective study covered a period of two years. Main inclusion criteria for the study was that pregnant women consume cigarettes during pregnancy. The research included respondents who had a singleton pregnancy, without pathological conditions that can affect the outcome and duration of pregnancy. Results: At the Obstetrics Clinic, Clinical Center University of Sarajevo in the period from January 1, 2012 to December 31, 2013. In that period 393 pregnant women completed labor who in the personal history had data on smoking during pregnancy. Of the total number of subjects enrolled in this study 38.17% smoked up to 10 cigarettes a day, 33.08 % smoked up to 20 cigarettes a day, while up to 30 cigarettes per day smoked 28.75 % of respondents. Conclusion: There was a significant difference in the average values of all anthropometric parameters, in relation to the number of cigarettes consumed by the subjects during the day. We also found negative correlation in the average values of anthropometric measures and the number of cigarettes consumed (p <0.05).
The myeloproliferative diseases (MPDs) or myelo-proliferative neoplasms (MPNs) are a group of diseases of the bone marrow in which excess cells are produced. Chronic idiopathic myelofibrosis (CIMF) is a stem cell defect characterized by splenomegaly with multiorgan extramedullary hematopoiesis, immature peripheral blood granulocytes and erythrocytes and progressive bone marrow fibrosis. The most common chromosomal abnormalities seen in CIMF patients include numerical changes of chromosomes 7, 8 and 9, and structural changes of 1q, 5q, 13q and 20q. At least 75.0% of patients with bone marrow abnormalities have one or more of these chromosomal anomalies. Detection of the Janus kinase 2 (JAK2) mutation may be a potential major breakthrough for understanding the pathobiology of MPNs, and is an essential part of the diagnostic algorithm. In this study, we describe a JAK2V617F mutation negative CIMF patient who has the chromosomal translocation t(3;12)(q26;q21) in her karyotype.
“Social Perspectives - Journal for Legal Theory and Practice“ is available in full text at the Central and Eastern European Online Library - CEEOL (www.ceeol.com) and on the web page www.ssrc.ibu.edu.ba
The vulnerability results of groundwaterbodies of southeastern Bosnia are shown in this paper. On the examined area 27 groundwater bodies were extracted, where 12 groundwaterbodies are in rocks with intergranular porosity and 15 groundwaterbodies are in rocks with karst-fissure porosity. All of the groundwater bodies were analysed through DRASTIC, GLA, PI and EPIK vulnerability determination methods, where the gained results are presented tabular. Depending on the porosity type, the vulnerability determination methods were used. So for intergranular groundwaterbodies the best results were gained by DRASTIC and GLA methods, while for the karst-fissure groundwater bodies the best results were gained by the EPIK method, which is the implementation of PI method.
SUMMARY Qualitative characteristics of bauxite deposit „Ostrelj“ are defined through extensive laboratory testing of chemical and mineralogical-petrographic composition, and geomechanical characteristics. Chemical composition has shown that it is a relative poor bauxite with low Al/Si module (2,28). Low values of Al/Si module are result of lower Al2O3 concentration (48 %), and higher SiO2 concentration (21 %), what these bauxites define as high silicic or »acidic«. Identified are increased concentrations of larger number of analyzed trace elements (B, Co, Cr, Li, Mn, Ni, Sn, V, Zn) comparing to the medium content in the Earth's crust. Mineralogical composition, structure and texture are uniform. Holders of Al mineralization are bemite and diaspor (to a lesser extent) as crypto-crystalline phases of rock matrix. Lower Cretaceous age (K1) of roof layers over bauxite deposit is paleontologicaly documented, while in the bauxite any fossils are not registrated. Values of geomechanical paramers of layers under and over bauxite is uniform. In bauxite value of compressive strength is increased, which is equivalent to chemical and mineralogical composition, and structural and textural characteristics of tested bauxite samples.
Background and purpose — Some patients have persistent symptoms after total hip arthroplsty (THA). We investigated whether the proportions of inferior clinical results after total hip arthroplasty—according to the 5 dimensions in the EQ-5D form, and pain and satisfaction according to a visual analog scale (VAS)—are the same in immigrants to Sweden as observed in those born in Sweden. Methods — Records of total hip arthroplasties performed between 1992 and 2007 were retrieved from the Swedish Hip Arthroplasty Register (SHAR) and cross-matched with data from the National Board of Health and Welfare and also Statistics, Sweden. 18,791 operations (1,451 in immigrants, 7.7%) were eligible for analysis. Logistic and linear regression models including age, sex, diagnosis, type of fixation, comorbidity, surgical approach, marital status, and education level were analyzed. Outcomes were the 5 dimensions in EQ-5D, EQ-VAS, VAS pain, and VAS satisfaction. Preoperative data and data from 1 year postoperatively were studied. Results — Preoperatively (and after inclusion of covariates in the regression models), all immigrant groups had more negative interference concerning self-care. Immigrants from the Nordic countries outside Sweden and Europe tended to have more problems with their usual activities and patients from Europe and outside Europe more often reported problems with anxiety/depression. Patients born abroad showed an overall tendency to report more pain on the VAS than patients born in Sweden. After the operation, the immigrant groups reported more problems in all the EQ-5D dimensions. After adjustment for covariates including the preoperative baseline value, most of these differences remained except for pain/discomfort and—concerning immigrants from the Nordic countries—also anxiety/depression. After the operation, pain according to VAS had decreased substantially in all groups. The immigrant groups indicated more pain than those born in Sweden, both before and after adjustment for covariates. Conclusion — The frequency of patients who reported moderate to severe problems, both before and 1 year after the operation, differed for most of the dimensions in EQ-5D between patients born in Sweden and those born outside Sweden.
UDK: 630*38:625.711.84(497.6 Sarajevo) The time period of forests opening and construction of forest truck roads in the analyzed area is longer than half of century. In such long time interval different types of vehicles for transport of timber assortments have been applied. Due to this fact technical elements of constructed roads are different. The vehicles currently used for the transport of timber assortments cause an accelerated destruction of forest truck roads due to inappropriate carriage way quality. Besides traffic load the forest truck roads are exposed to permanent atmospheric influences. The above specified and other reasons condition obligatory and regular maintenance and reconstruction of forest truck roads depends on the current condition of forest truck roads as well as on the plans for further use. In this article the condition of forest truck roads in the Forest management regions of Sarajevo Canton has been determined. The most frequent types of damages and causes of their occurrence have been registered. The methods for maintenance and rehabilitation-reconstruction of forest truck roads have been selected and their costs have been calculated. In the time when construction of new kilometers of forest truck roads is more and more rare, timely, adequate and financially justified maintenance of the existing network of forest truck roads is one of the key question for their undisturbed use. On the basis of results obtained in this research the guidelines for the time period and the ways of maintenance of forest truck roads have been given. The application of these guidelines should help in achieving of the best and most economical total results through the long-term use of forest truck roads.
Abstract The purpose of this study was to evaluate the genotoxic potential of components leached from two conventional self-curing glass-ionomer cements (Fuji IX and Ketac Molar), and light-curing, resin modified glass-ionomer cements (Vitrebond, Fuji II LC). Evaluation was performed on human lymphocytes using alkaline and hOGG1 modified comet, and micronucleus assays. Each material, polymerised and unpolymerised, was eluted in extracellular saline (1 cm2 mL-1) for 1 h, 1 day, and 5 days. Cultures were treated with eluates using final dilutions of 10-2, 10-3, and 10-4. Alkaline comet assay did not detect changes in DNA migration of treated cells regardless of the ionomer tested, polymerisation state, and elution duration. Glass ionomers failed to significantly influence micronucleus frequency. No oxidative DNA damage in treated lymphocytes was observed using hOGG1 modified comet assay. Obtained results indicate high biocompatibility of all tested materials used in the study under experimental conditions. Sažetak Svrha istraživanja bila je procijeniti genotoksični potencijal komponenata koje izlučuju dva konvencionalna samopolimerizirajuća stakleno-ionomerna cementa (Fuji IX i Ketac Molar) te svjetlosno polimerizirajući i smolom modificirani stakleno-ionomerni cementi (Vitrebond, Fuji II LC). Istraživanje je provedeno na ljudskim limfocitima primjenom alkalnog komet testa, komet testa modificiranog hOGG1 enzimom te mikronukleus testa. Svaki materijal, polimerizirani i nepolimerizirani, eluiran je u fiziološkoj otopini (1 cm2 mL-1) tijekom jednog sata, jednog dana i tijekom 5 dana. Kulture limfocita tretirane su eluatima u razrjeđenjima 10-2, 10-3 i 10-4. Alkalnim komet testom nisu zabilježene promjene u migraciji DNA iz tretiranih stanica bez obzira na ispitani ionomer, vrstu polimerizacije i trajanje elucije. Izloženost staklenim ionomerima nije značajno utjecala na učestalost mikronukleusa. Primjenom hOGG1 modificiranog komet testa nije zamijećeno oksidativno oštećenje DNA u tretiranim limfocitima. Dobiveni rezultati upućuju na visoki stupanj biokompatibilnosti svih testiranih materijala koji su se koristili u eksperimentalnim uvjetima.
Abstract. Raman microspectroscopy and quantitative backscattered electron imaging (qBEI) of bone are powerful tools to investigate bone material properties. Both methods provide information on the degree of bone matrix mineralization. However, a head-to-head comparison of these outcomes from identical bone areas has not been performed to date. In femoral midshaft cross sections of three women, 99 regions (20×20 μm2) were selected inside osteons and interstitial bone covering a wide range of matrix mineralization. As the focus of this study was only on regions undergoing secondary mineralization, zones exhibiting a distinct gradient in mineral content close to the mineralization front were excluded. The same regions were measured by both methods. We found a linear correlation (R2=0.75) between mineral/matrix as measured by Raman spectroscopy and the wt. %Mineral/(100-wt. %Mineral) as obtained by qBEI, in good agreement with theoretical estimations. The observed deviations of single values from the linear regression line were determined to reflect biological heterogeneities. The data of this study demonstrate the good correspondence between Raman and qBEI outcomes in describing tissue mineralization. The obtained correlation is likely sensitive to changes in bone tissue composition, providing an approach to detect potential deviations from normal bone.
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