Beta lactam antibiotics are widely used in therapy of cattle, particularly for the treatment of mastitis. Over 95% of residue testing in dairies in Bosnia and Herzegovina is for Beta lactams. The aim of this paper is to compare the efficacy of three most common screening tests for Beta lactam residues in cow's milk in our country. The tests used in the study are SNAP β Lactam test (Idexx), Rosa Charm β Lactam test and Inhibition MRL test. Study samples included: standardized concentrations of penicillin solution (0, 2, 3, 4, 5 and 6 ppb). In addition we tested milk samples from three equal size study groups (not receiving any antibiotic therapy, treated with Beta lactams for mastitis and treated with Beta lactams for diseases other than mastitis). Sensitivity and specificity were determined for each test, using standard penicillin concentrations with threshold value set at concentration of 4 ppb (Maximum residue level - MLR). Additionally we determined proportions of presumably false negative and false positive results for each test using results of filed samples testing. Agreement of test results for each test pair was assessed through Kappa coefficients interpreted by Landis-Koch scale. Detection level of all tests was shown to be well below MRL. This alongside with effects of natural inhibitors in milk contributed to finding of positive results in untreated and treated animals after the withholding period. Screening tests for beta lactam residues are important tools for ensuring that milk for human consumption is free from antibiotics residues.
Hypocalcaemia is a state with total calcium serum level below 2.25 mM/l. From the total serum calcium content, 50% is free and ionized, 40% is protein-bound and 10% is bound for organic anions. The most frequent causes of hypocalcaemia are iatrogenic hypoparathyroidism, magnesium deficit, disorders of vitamin D metabolism and chronic renal failure. Iatrogenic hypoparathyroidism is associated with low serum ionized calcium and low serum parathormone levels. There are two important clinical signs of hypocalcemia: Chvostek’s sign (twitches of upper lip after percussion on facial nerve over mandible) and Trousseau’s sign (carpal spasm after increasing pressure in blood pressure cuff placed about the upper arm for 20 milimeters above systolic pressure for 3-5 minutes). The following lab analyses should be performed when hypocalcaemia is an option: serum levels of calcium, magnesium, 25 – hydroxyvitamin, parathormone, potassium, sodium, chloride and bicarbonates. If hypocalcaemia is mild, it could be treated with oral calcium preparations, usually calcium carbonate, in a dose of 1 to 2 grams of elemental calcium daily. In more severe hypocalcaemia intravenous calcium-gluconate or calcium-chloride should be administered, as 10% solutions. These parenteral preparations of calcium should be diluted prior to the intravenous administration, and the administration should be longer than 20 minutes in order to avoid adverse effects on heart. If administration of calcium does not correct hypocalcaemia, oral vitamin D should be also prescribed. If this does not regulate calcaemia, from 0.25 tо 1 micrograms of 1,25-dihydroxyvitamin D (clacitriol) daily should be prescribed. Calcium serum levels should be kept within the lower part of normal serum concentration range.
We present a procedure to simultaneously design the output feedback law and the event-triggering condition to stabilize linear systems. The closed-loop system is shown to satisfy a global asymptotic stability property and the existence of a strictly positive minimum amount of time between two transmissions is guaranteed. The event-triggered controller is obtained by solving linear matrix inequalities (LMIs). We then exploit the flexibility of the method to maximize the guaranteed minimum amount of time between two transmissions. Finally, we provide a (heuristic) method to reduce the amount of transmissions, which is supported by numerical simulations.
The objective is to design output feedback event-triggered controllers to stabilize a class of nonlinear systems. One of the main difficulties of the problem is to ensure the existence of a minimum amount of time between two consecutive transmissions, which is essential in practice. We solve this issue by combining techniques from event-triggered and time-triggered control. The idea is to turn on the event-triggering mechanism only after a fixed amount of time has elapsed since the last transmission. This time is computed based on results on the stabilization of time-driven sampled-data systems. The overall strategy ensures an asymptotic stability property for the closed-loop system. The results are proved to be applicable to linear time-invariant (LTI) systems as a particular case.
O uso desordenado dos recursos resulta por muitas vezes problemas ao meio ambiente. Para um melhor planejamento da superacao de problemas envolvendo o uso excessivo dos recursos naturais, torna-se necessario o conhecimento dos usos que alteram a superficie terrestre. O objetivo deste trabalho foi realizar o mapeamento do uso do solo no modulo IV da Floresta Estadual do Amapa – FLOTA/AP e de areas de seu entorno, bem como identificar seus atores. Para a realizacao da classificacao do uso do solo a partir da classificacao de desmatamento de Silva et al. (2012), foram criadas novas categorias de usos predominantes na area de estudo (mineracao, urbano, agricultura, pecuaria e transporte/comunicacao) no software Envi 4.7, utilizando a chave de identificacao de Anderson et al. (1976) e elementos de fotointerpretacao. Os usos do solo foram classificados, quantificados e identificados os seus atores. Os usos que apresentaram maiores indices de ocupacao na area foram agricultura e pecuaria. Os usos do solo tiveram como principais atores: fazendas, projetos de assentamento agrario e aldeias indigenas. Esses usos se encontram principalmente nas proximidades das estradas oficiais.
Abstract In this paper the focus is on the intellectual styles of the Bosnian students which are presented through the prism of the Threefold Model of intellectual styles. The participants, 45 graduate students, completed the Bosnian version of the Thinking Styles Inventory (TSI). The results showed the following: a) acceptability, the three-dimensional structure of TSI, which is in line with contemporary research on intellectual styles, b) dominance of Type I, creativity-generating intellectual styles on norm-favoring, the Type II intellectual styles. The implications of these findings from the cross-cultural standpoint are discussed in this paper.
Investigamos as dificuldades que os alunos de Quimica/Licenciatura do Campus de Itabaiana tem com o texto academico, com aplicacao do teste Cloze aos alunos das turmas de Fundamentos de Fisico Quimica e de Fisico Quimica I do curso de Quimica/Licenciatura do Campus de Itabaiana, do 1o semestre de 2012. O instrumento conta com 73 vocabulos de um texto a serem preenchidos pelos alunos. Participaram do teste 23 alunos de Fisico Quimica I e 5 alunos de Fundamentos de Fisico Quimica . Os resultados obtidos foram aplicados a escala de Bormuth (1968) para proficiencia em leitura, com os niveis frustracao, instrucional e independente, e a produtividade na identificacao das palavras-chave do texto. Concluimos que ha um deficit com relacao a proficiencia em leitura dos alunos de Fundamentos de Fisico Quimica e possivelmente podemos estender este deficit aos demais alunos do curso de Licenciatura em Quimica.
Contemporary inhabitants of the Balkan Peninsula belong to several ethnic groups of diverse cultural background. In this study, three ethnic groups from Bosnia and Herzegovina - Bosniacs, Bosnian Croats and Bosnian Serbs - as well as the populations of Serbians, Croatians, Macedonians from the former Yugoslav Republic of Macedonia, Montenegrins and Kosovars have been characterized for the genetic variation of 660 000 genome-wide autosomal single nucleotide polymorphisms and for haploid markers. New autosomal data of the 70 individuals together with previously published data of 20 individuals from the populations of the Western Balkan region in a context of 695 samples of global range have been analysed. Comparison of the variation data of autosomal and haploid lineages of the studied Western Balkan populations reveals a concordance of the data in both sets and the genetic uniformity of the studied populations, especially of Western South-Slavic speakers. The genetic variation of Western Balkan populations reveals the continuity between the Middle East and Europe via the Balkan region and supports the scenario that one of the major routes of ancient gene flows and admixture went through the Balkan Peninsula.
P. Lazić,1 G. M. Sipahi,2,* R. K. Kawakami,3 and Igor Žutić2,† 1Rudjer Bošković Institute, PO Box 180, Bijenička c. 54, 10 002 Zagreb, Croatia 2Department of Physics, University at Buffalo, State University of New York, Buffalo, New York 14260, USA 3Department of Physics, The Ohio State University, Columbus, Ohio 43210, USA (Received 17 February 2014; revised manuscript received 1 August 2014; published 22 August 2014)
Sustainability and energy-efficiency are receiving increasing attention. Existing buildings are responsible for more than 40% of the worlds total primary energy consumption. Current building management systems fail to reduce unnecessary energy consumption and preserve to user comfort at the same time mainly because they are unable to cope with dynamical changes caused by user’s interaction with the environment. To cope with this dynamicity, we propose a software architecture for energy smart buildings that includes a set of concrete software solutions that tackle energy consumption sub-systems; i.e., heating, ventilation and air conditioning (HVAC), lighting, workstations and other appliances subsystems, in order to save significant amount of energy whilst preserving user comfort. Experimental results carried out in a 12.000 square meter building of the University of Groningen show that our proposed solutions are able to save up to 56% of electricity used for lighting, at least 20% of electricity used for heating while the savings from controlling workstation as well as other appliances are 33% and 10%, respectively.
Analysis of power consumption presents a very important issue for power distribution system operators. Some power system processes such as planning, demand forecasting, development, etc.., require a complete understanding of behaviour of power consumption for observed area , which requires appropriate techniques for analysis of available data. In this paper, two different time-frequency techniques are applied for analysis of hourly values of active an d reactive power consumption from one real power distribution transformer substation in urban part of Sarajevo city . Using the continuous wavelet transform (CWT) with wavelet power spectrum and global wavelet spectrum some properties of analysed time series are determined. Then, empirical mode decomposition (EMD) and Hilbert -Huang Transform (HHT) are applied for the analyses of the same time series and the results show ed that both applied approaches can provide very useful information about the behaviour of power consumption for observed time interval and different period (frequency) bands. Also it can be noticed that the results obtained by global wavelet spectrum and marginal Hilbert spectrum are very similar, thus confirming that both approaches could be used for identification of main properties of active and reactive power consumption time series .
A mumps outbreak reported from the Federation of Bosnia and Herzegovina involved 7,895 cases between December 2010 and September 2012. This was the largest outbreak in the country since the introduction of the measles, mumps and rubella vaccine in 1980. The highest disease incidence was found among 15 to 19 year-olds. About 39% (3,050/7,895) of cases reported to be unvaccinated; the vaccination status of 31% (2,426/7,895) was unknown. A seroprevalence study among 150 asymptomatic contacts to mumps cases showed that about one third (45/150) were susceptible to mumps. Among 105 clinically suspected mumps patients hospitalised at the Clinical Centre of the University of Sarajevo, orchitis (60% of all males: 51/85) and meningitis (9%: 9/105) were the most common complications. Among 57 outbreak sequences obtained for the small hydrophobic gene, eight different variants of genotype G viruses were identified. The outbreak affected mainly age groups comprising individuals who were not vaccinated during or after the Bosnian war, as well as cantons with single dose immunisation policies until 2001. In addition to issues related to vaccination of individuals, differential responses to vaccines and vaccine strains, waning of antibodies and potentially also the genetically diverse variants of genotype G may have compounded the size and duration of the outbreak. Our report emphasizes the need for supplementary immunisation programmes in particular for adolescents and young adults.
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