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This paper presents implementation of optimal search strategy (OSS) in verification of assembly process based on neural vibration learning. The application problem is the complex robot assembly of miniature parts in the example of mating the gears of one multistage planetary speed reducer. Assembly of tube over the planetary gears was noticed as the most difficult problem of overall assembly. The favourable influence of vibration and rotation movement on compensation of tolerance was also observed. With the proposed neural-network-based learning algorithm, it is possible to find extended scope of vibration state parameter. Using optimal search strategy based on minimal distance path between vibration parameter stage sets (amplitude and frequencies of robots gripe vibration) and recovery parameter algorithm, we can improve the robot assembly behaviour, that is, allow the fastest possible way of mating. We have verified by using simulation programs that search strategy is suitable for the situation of unexpected events due to uncertainties.

M. Djurić, J. Mladenović, B. Radovanović, S. Murtić, G. A. ćamović-Djoković

Pseudogley is a typical type of acid soils predominating in both Serbia and the wider region. Acid soils are not suitable for the cultivation of agricultural crops due to the hampered uptake of most nutrients as induced by increased levels of hydrogen ions. In order to make pseudogley soil suitable for crop production, pH improvement measures should be employed. The objective of this study was to use liming to neutralise soil acidity and evaluate the effect of soil pH improvement measures on the Mo content in both root and leaf of the Dutch tomato ( Lycopericon esculentum Mill.) hybrid Belle planted under controlled conditions on pseudogley soil. Molybdenum was studied in this paper due to its role in plant nitrogen metabolism. Moreover, the determination of molybdenum presence in the root and leaf is a sure indicator of successful liming effects. Three liming treatments were employed (1, 3 and 4 t/ha CaCO 3 ). The liming operation used on pseudogley induced a statistically significant increase in molybdenum ion absorption into the root system of tomato. Independently from the aforementioned, the values for the root and leaf molybdenum content of tomato in each treatment were very low and insufficient for successful growth of this plant. In order to make pseudogley suitable for successful development of agricultural production, it is necessary to increase both soil pH and the content of available molybdenum in the soil. Key words: Liming, pseudogley, molybdenum, leaf, root, tomato.

I. Čavar, T. Kelava, D. Pravdić, F. Culo

Prostanoids are lipid compounds that mediate a variety of physiological and pathological functions in almost all body tissues and organs. Thromboxane (TX) A2 is a powerful inducer of platelet aggregation and vasoconstriction and it has ulcerogenic activity in the gastrointestinal tract. Overdose or chronic use of a high dose of acetaminophen (N-acetyl-paminophenol, APAP) is a major cause of acute liver failure in the Western world. We investigated whether TXA2 plays a role in host response to toxic effect of APAP. CBA/H Zg mice of both sexes were intoxicated with a single lethal or high sublethal dose of APAP, which was administered to animals by oral gavage. The toxicity of APAP was determined by observing the survival of mice during 48 h, by measuring concentration of alanine-aminotransferase (ALT) in plasma 20-22 h after APAP administration and by liver histology. The results have shown that anti-thromboxane (TX) B2 antibodies (anti-TXB2) and a selective inhibitor of thromboxane (TX) synthase, benzylimidazole (BZI), were significantly hepatoprotective, while a selective thromboxane receptor (TPR) antagonist, daltroban, was slightly protective in this model of acute liver injury. A stabile metabolite of TXA2, TXB2, and a stabile agonist of TPR, U-46619, had no influence on APAP-induced liver damage. Our findings suggest that TXA2 has a pathogenic role in acute liver toxicity induced with APAP, which was highly abrogated by administration of anti-TXB2. According to our results, this protection is mediated, at least in part, through decreased production of TXB2 by liver fragments ex vivo .

J. Vuković, Sanda Telen, V. Srića, P. Novak

An approach has been proposed combining one dimensional inverse gated 13C NMR spectroscopy and a comprehensive two dimensional gas chromatography (GC×GC) to analyze diesel fuels prior and after oxidation under the standard conditions. Classes of hydrocarbons present before and after oxidation have been identified and quantified. A decrease in aromatic iso- and n-paraffinic hydrocarbons and an increase in the total saturated hydrocarbons have been observed after oxidation. In that respect NMR spectroscopy has potential to be used as standard method for determination of oxidation stability. Furthermore, GC×GC has been applied to identify compounds involved in the formation of sediments during oxidation. Obtained results have shown that hydrocarbon composition, especially the normal paraffin content play a role in the formation of sediments in these distillate fuels. This is important since sediments may influence the quality of diesel fuels.

Muris Pecar, D. Avdić, D. Pecar

Introduction: Trigger Finger (tenosynovitis stenosans) is a specific, named disease from a group of repetitive strain injury (RSI) diseases, caused by inflammation which results in difficulties during muscle contraction and weakened and painful tendon movement. It is common in the outpatient physical medicine and rehabilitation practice. The aim of our study was to evaluate the success of conservative treatment of Trigger Finger by local instillation of corticosteroids.Methods: The study was designed as an observational and open analysis of the results of conservative treatment of 45 patients. We used precise instillation of steroid anti-inflammatory antirheumatic drugs in the area of patho-anatomic, microtraumatic injuries of tendon and its sheath. Patients were evaluated before and after the treatment with 0 to 5 evaluation score scale. The data were analyzed using X2 test.Results: Most of the patients had evaluation score of 2, 3 and 4, before the treatment. After the treatment 10 (29%) patients had achieved score 4 and 35 (71%) patients had achieved score 5. All of the patients with score 5 had excellent working ability with full working capacity. Other patients had well-preserved working ability, which improved to excellent in maximum of 7 days.Conclusions: Conservative treatment of Trigger finger shows good therapeutic effects and taking into account the benefits, convenience and generally lower cost of conservative treatment for the patient, should be considered as an effective alternative to surgical treatment.

Suvada Švrakić, Amer Ovčina

Introduction: Information systems today are an inevitable link in the health care system. Health care institutions and health workers in modern society, depend on information systems in everyday tasks of organizing institutions.The goals of the study were to determine the existence and application of information technology in the health care system and of the Clinical Center of Sarajevo University and, Primary Health Care Center of Sarajevo Canton, as well as to assess knowledge and practice of managers in nursing of the Organizational units of the University Clinical Center in Sarajevo and Primary Health Care Center of Sarajevo Canton.Method: The study is of a prospective type. It will use a questionnaire based on which we will be able to determine the knowledge and application in practice of managers in nursing of knowledge about information technology in the health care system. The study was conducted from June 1st – August 1st 2010.Results: It is expected that most health institutions in the Canton Sarajevo has no organized information network system. Most managers’ nurses use e-mail in order to quickly contact other colleagues and exchange experiences. A large number of nurse’s managers in health institutions use computer technology in their daily work in order to make medical reports.Conclusions: Health system and information technology are in close relationship, although still insufficiently applied in everyday work. Management of organizational units in health care in the future will not be able to successfully function without the use of information technology in their daily work.

Introduction: The aim of this study was determination of troponin I at serum using Architect (Abbott) and AxSYM System (Abbott). Troponin is regulatory subunit of the troponin complex associate with actin filament within muscle cells and it is a marker for diagnosis of myocardial damage.Methods: We used Architect STAT chemiluminescent microparticle immunoassay (CMIA) and AxSYM microparticle Enzyme Immunoassay (MEIA), techniques for quantitative determination of cardiac TnI in human serum or plasma. At our study we have proved precision, reproducibility and accuracy from both methods. The investigation included patients (n=119) who have myocardial infarction or ischemic heart damage and were treated at cardiology, emergency, internal medicine and neurology unit in Clinical Center University in Sarajevo.Results: The precision for three controls using Architect STAT TnI asssay technology were 3.6 – 5.2 % and reproducibility was 3.7 to 5.6 %. The AxSYM STAT TnI has precision for three controls 4.3–6.6 % and reproducibilitywas from 4.8 to 7.8 %. We have got very good correlation between Architect and AxSYM technology r = 0.999 in the investigation of troponin I in serum.Conclusions: We can conclude that chemiluminescent troponin assay I (Architect) showed good analytical performance and gave new possibility at troponin I determination.

Introduction: The aim of this paper is to study the distribution of the therapy dosage applied by a modified conventional “field in field” technique and compare it to the distribution of the dosage applied by the standard conventional technique.Methods: The study included ten patients with right side breast cancer, after they were exposed to radical mastectomy and chemotherapy. Radiotherapy dosage of TD 50 Gy in 25 fractions was applied to the anterolateral side of the right thoracic wall, with two opposite conventional tangential fields by the linear accelerator Elekta Synergy and the energy of 6 megavolts (MV). A delineation of the target volume (CTV – Clinical Target Volume) was done within conventional fields. At the XiO system for planning we included additional fields within the existing conventional fields, which was the so called “field in field” technique. On the basis of CTV the Dose Volume  Histogram (DVH) was calculated for conventional and “field in field” plans. VD90%, VD95%, VD107%, VD115%, CI and HI were calculated for both techniques. Means were pared with the paired Student's t-test. The results were considered significantly different if p<0.05.Results: VD90% and VD 95% were significantly higher for the “field in field” technique. Therefore, CI also favored the “field in field” technique (p=0.02). There was no difference in VD107% and VD115% between the compared groups. Consequently, there was no statistically significant difference in HI (1.13±0.03 vs.1.13±0.03, p=0.06).Conclusion: Conventional postoperative radiotherapy of localized right side breast cancer by “field in field” technique provides excellent coverage of the target volume by radiotherapy isodose.

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