INTRODUCTION Authors report their clinical experience in managing a 46-year-old male patient with long lasting nose breathing difficulties caused by nasal obstruction due to a large bilateral tumor masses in both nasal cavities. CASE OUTLINE Physical examination, laboratory and biochemistry analyses, as well as computed tomography showed an inhomogeneous soft-tissue tumor mass completely filling both nasal cavities, maxillary, ethmoidal, sphenoidal, and frontal sinuses on both sides, accompanied by destruction of bony walls of all sinuses. Preoperative histopathology analysis showed a polyp with squamous metaplasia.The gigantic polypoid mass was removed by bicoronal approach to the frontal and ethmoidal sinuses and by direct approach to the maxillary sinuses and nasal cavity. Definite histopathology analysis confirmed the initial diagnosis, but the presence of fungal hyphae in allergic mucus was also observed. CONCLUSION Polypoid growth in the nose rarely grow to such gigantic dimensions that it causes destruction of all walls of paranasal sinuses. Considering so far published reports from the literature, the presented case is among the biggest nasal polyps reported until now.

Abstract With this paper the authors aim not only to investigate the lifestyle specifics of the Western Balkan market, but also to define common lifestyle segments for the entire region. The question addressed in this research is whether current political issues and economic differences have led to dissimilar ways of living, or whether cultural similarities have prevailed and lifestyles can be defined accordingly. Based on the research conducted using six underlying factors, three lifestyle clusters are identified. Analysis shows that there are three almost identical lifestyles for Bosnia and Herzegovina, Croatia, Serbia and Slovenia, and they are applicable to the entire region. These findings have significant managerial implications, as potential investors can apply identical marketing strategies to target the approximately 20 million consumers in the region.

Dear Editor, With the number of percutaneous coronary interventions (PCIs) on the rise, it is expected that there will be a corresponding growth in population of patients with prior PCI referred to coronary artery bypass grafting (CABG) as a result of long-term PCI failure, incomplete revascularization, or coronary artery disease progression. The prevalent position of the interventional cardiologists of: ‘‘subsequent CABG may be successfully performed in any patient with a history of previous PCI’’ is now being seriously challenged. Furthermore, results of several studies that investigated the impact of previous PCI on subsequent CABG were found to be conflicting. For this reason, we read with great interest the article by Niclauss et al. regarding the influence of prior PCI on subsequent CABG. There are only a few studies reporting onmidor long-term results following surgical revascularization in patients with prior PCI, and from that point of view the article by Niclauss et al. is indeed a very fine contribution. This study produced another very important conclusion—there is no difference in terms of mortality depending on prior PCI status. However, a cautionary warning was identified in that particular study: the proportion of patients who underwent isolated percutaneous transluminal angioplasty (PTCA)—20% in PCI prior CABG group—looks to be far too big for contemporary clinical practice in our view. Having in mind different pathophysiological mechanisms responsible for PTCA and PCI failure, we believe that such a large number of patientsmight, in fact, skew the results of the study. We, therefore, think that excluding the subgroup of patients would yield results that would be more representative of a contemporary practice. In Table 1, it is indicated that a proportion of patients with prior myocardial infarction (MI) is very similar between the groups (40% vs. 44%, p1⁄4 0.07). Does this mean that the patients with MI were not treated with PCI in large number? The report did not appear to indicate the number of patients having previous MI treated with PCI that were subsequently referred to CABG. For the purpose of analysis, it would be useful to see in what percentage was the artery, already treated with stent, revascularized surgically. Another factor worthy of attention is the number of multiple PCIs and its influence on CABG. Based on our clinical practice, we know that cardiologists are likely to be very persistent in their attempts to percutaneously revascularize the artery. Table 2 of Niclauss et al. paper counts 22.3% (89) prior-PCI patients taking clopidogrel which seems quite low. We seek explanation about how long the patients took the drug following PCI. Again, 77.7% of patients with previous PCI were merged with those not submitted to PCI when the impact of active double anti-platelet therapy was investigated. We believe that conclusions would be more accurate (meaningful) if only the original groups were considered. Careful decision-making in the setting of multivessel disease is mandatory. Obviously, many risk factors (patient related, procedure related, drug related, coronary artery anatomy, and pathology) may influence the success or failure of specific procedures, thus emphasizing the need for adequate patient selection according to corresponding procedure type. In order to gain meaningful insight about the relation between PCI and subsequent CABG, more contemporary studies including a larger proportion of patients treated with drug eluting stents and/or biodegradable stents are highly warranted. Conflict of interest: The authors acknowledge no conflict of interest in the submission.

We define a set of pseudo-observables characterizing the properties of Higgs decays in generic extensions of the Standard Model with no new particles below the Higgs mass. The pseudo-observables can be determined from experimental data, providing a systematic generalization of the “κ\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\kappa $$\end{document}-framework” so far adopted by the LHC experiments. The pseudo-observables are defined from on-shell decay amplitudes, allow for a systematic inclusion of higher-order QED and QCD corrections, and can be computed in any Effective Field Theory (EFT) approach to Higgs physics. We analyze the reduction of the number of independent pseudo-observables following from the hypotheses of lepton universality, CP invariance, custodial symmetry, and linearly realized electroweak symmetry breaking. We outline the importance of kinematical studies of h→4ℓ\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$h\rightarrow 4\ell $$\end{document} decays for the extraction of such parameters and present their predictions in the linear EFT framework.

Abstract Background: Competition in the banking industry has been an important topic in the scientific literature as researchers tried to assess the level of competition in the banking sector. Objectives: This paper has an aim to investigate the market structure and a long term equilibrium of the banking market in Bosnia and Herzegovina nationwide as well as on its constitutional entities as well as to evaluate the monopoly power of banks during the years 2008-2012. Methods/Approach: The paper is examining the market structure using the most frequently applied measures of concentration k-bank concentration ratio (CRk) and Herfindahl-Hirschman Index (HHI) as well as evaluating the monopoly power of banks by employing Panzar-Rosse “H-statistic”. Results: The empirical results using CRk and HHI show that Bosnia and Herzegovina banking market has a moderately concentrated market with a concentration decreasing trend. The Panzar-Rosse “H-statistic” suggests that banks in Bosnia and Herzegovina operate under monopoly or monopolistic competition depending on the market segment. Conclusions: Banks operating on the banking market in Bosnia and Herzegovina seem to be earning their total and interest revenues under monopoly or perfectly collusive oligopoly.