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7. 3. 2016.
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C. Bartneck, Y. Nagai, Ana Paiva, S. Šabanović

We are excited to welcome you to the Eleventh Annual ACM/IEEE International Conference on Human-Robot Interaction (HRI 2016). The HRI Conference is a highly selective, single track, international meeting showcasing the best research in human-robot interaction, with roots in and broad participation from various communities of scholars, including but not limited to robotics, human-computer interaction, artificial intelligence, engineering, social and behavioral sciences, and design.

C. Bartneck, Y. Nagai, Ana Paiva, S. Šabanović

We are excited to welcome you to the Eleventh Annual ACM/IEEE International Conference on Human-Robot Interaction (HRI 2016). The HRI Conference is a highly selective, single track, international meeting showcasing the best research in human-robot interaction, with roots in and broad participation from various communities of scholars, including but not limited to robotics, human-computer interaction, artificial intelligence, engineering, social and behavioral sciences, and design. The theme of this year's conference is "Natural Interaction," an increasingly important research focus and design goal as robotic technologies become incorporated into everyday life. Achieving natural human-robot interaction requires the input of many technical, social, and design disciplines, as well as reflection on the societal consequences and ethical significance of robotic development. To represent the multitude of disciplines and approaches that contribute to this work and the HRI field more generally in the conference program, we solicited and reviewed papers under four submission themes: "Studies of HRI", "Technical Advancements in HRI", "HRI Design", and "Theory and Method in HRI." Each submission theme was overseen by a dedicated theme chair and reviewed by a dedicated group of program committee members, who worked together with the program chairs to define and apply review criteria appropriate to each of the four contribution types. The conference attracted 181 submissions from Asia-Pacific, Europe, the Middle East, and North America. Each full paper was aligned with a theme-appropriate subcommittee, and subsequently reviewed through a double-blind process, which was followed by a rebuttal phase, and shepherding where suggested by the program committee. As a result of the review process, the program committee selected 45 (24.8%) of the submissions for presentation as full papers at the conference. As the conference is jointly sponsored by IEEE and ACM, papers are archived in both IEEE Xplore and the ACM Digital Library. Along with the full papers, the conference program and proceedings include the Late Breaking Reports, Videos, Demos, and a new alt.HRI section. Out of 95 total submissions, 71 (74.7%) Late Breaking Reports were accepted and will be presented as posters at the conference. Eleven (85%) short videos were accepted for presentation during a dedicated video session from 13 submissions. The program also includes four demos of robot systems that participants will have an opportunity to interact with during the conference. We're very excited to introduce an alt.HRI session in this year's program, consisting of five papers (selected out of 11 submissions) that push the boundaries of thought and practice in the field. Finally, we have the pleasure of presenting three inspiring keynote speakers who will discuss topics relevant to HRI: Dr. Aude Billard from EPFL in Switzerland, Dr. Marc Sagar from the University of Auckland in New Zealand, and Dr. Robert Sparrow from Monash University in Australia.

Hee Rin Lee, S. Šabanović, Erik Stolterman

Robot designers commonly emphasize humanlikeness as an important design feature to make robots social or user-friendly. To understand how users make sense of the design characteristics of robots, we asked 6 participants to classify and interpret the appearance of existing robots in relation to their function and potential usefulness. All the robots had humanlike aspects in their design, and participants most commonly remarked on these humanlike features of the robots. However, the commonsense logic of the “Uncanny Valley” (UV) in HRI design, which suggests that robots should be similar to humans to some degree without being too humanlike, was not supported by participant comments, which did not correlate humanlikeness to user-friendliness in line with the UV hypothesis. Rather, participants related the design features of robots to their everyday contexts, and focused their commentary on context-dependent design implications. As a result, we suggest our understanding of the design characteristics of robots should include the perspectives of users from the earliest stages of design so we can understand their contextual interpretations of different design characteristics. Open and modularized technical platforms could support the inclusion of users in the creation of future social robots.

A. Kurtovic-Kozaric, Lejla Mehinovic, Meliha Stomornjak-Vukadin, Ilvana Kurtovic-Basic, F. Catibusic, Mirza Kozaric, S. Dinarevic, M. Hasanhodžić et al.

Microdeletion syndromes are caused by chromosomal deletions of less than 5 megabases which can be detected by fluorescence in situ hybridization (FISH). We evaluated the most commonly detected microdeletions for the period from June 01, 2008 to June 01, 2015 in the Federation of Bosnia and Herzegovina, including DiGeorge, Prader-Willi/Angelman, Wolf-Hirschhorn, and Williams syndromes. We report 4 patients with DiGeorge syndromes, 4 patients with Prader-Willi/Angelman, 4 patients with Wolf-Hirschhorn syndrome, and 3 patients with Williams syndrome in the analyzed 7 year period. Based on the positive FISH results for each syndrome, the incidence was calculated for the Federation of Bosnia and Herzegovina. These are the first reported frequencies of the microdeletion syndromes in the Federation of Bosnia and Herzegovina.

Great scientific discoveries rarely originate from small and poor countries. However, the lives and achievements of three Yugoslav scientists who were active in the biomedical sciences, Laza K. Lazarevic (1851-1891), Ivan Djaja (1884-1957), and Pavao Stern (1913-1976), serve as an example of success in this environment. These scientists, as well as the majority of other successful investigators in small and poor countries, were trained in foreign and developed countries and, upon return, were given the freedom to start a self-dependent research program. They overcame many obstacles, including wars and civil unrests, to contribute significantly to certain medical fields. It is interesting that although a Jew, Stern was allowed to work during the World War II in Zagreb, which became capital of the so-called Independent State of Croatia, a puppet state under German control. Perhaps his good name among pharmacologists helped him to keep position during this tough period. Nowadays, new technologies needed for biomedical research are rather expensive, and poor countries cannot afford to finance many scientists. Thus, selection of the most productive researchers is the challenge for those who finance scientific work.

G. Bogdanovic, A. Djordjevic

Since their discovery, fullerenes, carbon nanotubes, and graphene attract significant attention of researches in various scientific fields including biomedicine. Nano-scale size and a possibility for diverse surface modifications allow carbon nanoallotropes to become an indispensable nanostructured material in nanotechnologies, including nanomedicine. Manipulation of surface chemistry has created diverse populations of water-soluble derivatives of fullerenes, which exhibit different behaviors. Both non-derivatized and derivatized fullerenes show various biological activities. Cellular processes that underline their toxicity are oxidative, genotoxic, and cytotoxic responses.The antioxidant/cytoprotective properties of fullerenes and derivatives have been considered in the prevention of organ oxidative damage and treatment. The same unique physiochemical properties of nanomaterials may also be associated with potential health hazards. Non-biodegradability and toxicity of carbon nanoparticles still remain a great concern in the area of biomedical application. In this review, we report on basic physical and chemical properties of carbon nano-clusters--fullerenes, nanotubes, and grapheme--their specificities, activities, and potential application in biological systems. Special emphasis is given to our most important results obtained in vitro and in vivo using polyhydroxylated fullerene derivative C₆₀(OH)₂₄.

M. Prskalo, Željka Tomić, K. Novak-Lauš, Zrinko Prskalo

The aim of the study was to evaluate macular thickness and macular volume in unilateral and bilateral exfoliation syndrome and to compare them with exfoliative glaucoma and control eyes using optical coherence tomography. This prospective study included 114 subjects (228 eyes) divided into 4 groups according to the presence of exfoliation: 30 patients with unilateral syndrome, 24 patients with bilateral syndrome, 28 patients with bilateral glaucoma and control group without glaucoma or exfoliation syndrome (32 subjects). All subjects were older than 50 years. Patients with visual acuity under 0.6 according to Snellen were excluded, as well as those with refraction errors, i.e. hypermetropia over +3 spherical diopters, myopia over -5 spherical diopters, astigmatism over 2 cylindrical diopters, patients with affections that might affect the macula or the optic nerve, such as diabetic retinopathy, macular degeneration, macular edema, epiretinal membrane, vascular occlusions, neuropathies, and patients having undergone eye surgery except for pseudophakic patients with visual acuity within the set limits. Study results confirmed the hypothesis on the existence of structural changes of macular parameters before the functional ones, thus representing an early sign of glaucomatous damage in risk groups such as unilateral and bilateral exfoliation syndrome. If the glaucoma had already manifested (exfoliative glaucoma in this study) with changes in optic disc and visual field, structural changes confirmed the clinical findings and warned of the disease severity.

Z. Mujagic, D. Keszthelyi, A. Y. Thijssen, D. Jonkers, A. Masclee

depletion alters gastrointestinal and anxiety symptoms in irritable bowel syndrome. Am J Gastroenterol 2006; 101: 2582–7. 8. Labus JS, Mayer EA, Jarcho J, et al. Acute tryptophan depletion alters the effective connectivity of emotional arousal circuitry during visceral stimuli in healthy women. Gut 2011; 60: 1196–203. 9. Spiller R. Serotonin and GI clinical disorders. Neuropharmacology 2008; 55: 1072–80. 10. Thijssen AY, Mujagic Z, Jonkers DM, et al. Alterations in serotonin metabolism in the irritable bowel syndrome. Aliment Pharmacol Ther 2016; 43: 272–82. 11. Fitzgerald P, Cassidy Eugene M, Clarke G, et al. Tryptophan catabolism in females with irritable bowel syndrome: relationship to interferon-gamma, severity of symptoms and psychiatric co-morbidity. Neurogastroenterol Motil 2008; 20: 1291–7. 12. Drossman DA, Morris CB, Hu Y, et al. A prospective assessment of bowel habit in irritable bowel syndrome in women: defining an alternator. Gastroenterology 2005; 128: 580–9.

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