The cold drawing process takes places very quickly and during the conversion of mechanical energy into the heat energy the work peace and the tool heat up considerably. In order to achieve a stabile drawing process, it is necessary to keep tracks of the temperature growth of the work piece and the tool. The tool temperature has to be below the established limits, and it is regulated by the amount of the coolant, which is at the same time also a lubricant. The expressions for the temperature growth calculation in the conditions of adiabatic processes that can also be applied to the deep drawing process with the reduction of the wall thickness, due to the high deformation rate, have been presented in the work. The heat balance equation enables the determination of the coolant mass which will maintain the stabile tool temperature, what is confirmed by the experimental researches.
Introduction: In the present study we investigated the performance, precision, and recovery of three different automated methods in determining cancer antigen (CA) 15-3 levels.Methods: Serum samples were obtained from 60 hospitalized female patients. As controls, commercially available samples were used. Cancer antigen (CA) 15-3 levels were measured using ARCHITECT CA 15-3, Elecsys® CA 15-3, and Vitros CA 15-3 immunoassays. A comparison of the results between the three methods was conducted, and the precision and recovery were analyzed.Results: Coefficient of variations (CVs), determined with low- and high-level-CA 15-3 control samples, and reproducibility values were: 2.56-2.80% and 3.10-4. 20% for ARCHITECT i2000SR immunoassay analyzer; 3.50-5.55% and 4.88-6.47% for Cobas E 601 analyzer; 3.30-4.0% and 4.30-4.80% for VITROS 5600 Integrated System, respectively. The percent recoveries were 95-98% for Elecsys® CA 15-3 assay, 93-105% for Vitros CA 15-3 assay, and 92-95% for ARCHITECT CA 15-3 assay. Method comparison results demonstrated correlation coefficient (r) in range from 0.994 to 1. The average CA 15-3 concentrations measured by Vitros, ARCHITECT, and Elecsys® were 157.24 +/- 329.75 U/mL, 100.91 +/-213.75 U/mL, and 80.93 +/- 173.29 U/mL, respectively.Conclusions: Tumor marker CA 15-3 in individual patients should be monitored using the same immunoassay method, reagents, and analyzer. Different immunoassays tested on different analyzers, often show large discrepancies in reported values for individual patients. Different immunoassay technologies quantify analytes of clinical interest using monoclonal or polyclonal antibodies. Thus, the usage of antibodies with different specificities could explain the differences in CA 15-3 serum values between different methods.
Impact machines are designed to generate high dynamic forces with each impact hammer. Conventionally designed bases of these machines require relatively large reinforced concrete blocks to transfer the impact force to the ground. Size basic block is dependent on a loading force produced a hammer and the characteristics of the soil. The vibrations generated by blows of hammers also be transmitted to the ground. These vibrations can have large impact and consequences on equipment, employees and even to the building structure. Recently, large investments in research and development of new technologies vibration isolation for impact machinery using the steel coil springs and viscous fluid dampers. The old solutions of elastic foundations are required large inertial mass under the hammer. With constant research and development to come up with new solutions that provide direct support to the impact machines using springs, without using a inertial mass.
Appian’s Illyrian book ( Illyrike ) was originally intended to be just an appendix to his Macedonian book and today remains the only extant ancient work dealing with the early history of Illyricum which is preserved in its entirety. In this short work Appian puts together different local and regional histories in order to create a unified historical narrative and determines the historical and mythological coordinates of Illyricum inside the ancient world. This paper will discuss Illyrike in the context of the Roman construction of Illyricum as a provincial space, similar to some other regions in continental Europe such as, for example, Gaul or Britain. They were all firstly created through the needs of Roman political geography and later written into literary knowledge through the works of ancient history and ethnography. This paper will argue that Appian’s Illyrik e represented the final stage of the Roman construction of Illyricum from an imaginary to a provincial space, which was the point of its full coming of age as an integral part of the ancient world and the Roman Empire.
A trigonometric series strongly bounded at two points and with coefficients forming a log-quasidecreasing sequence is necessarily the Fourier series of a function belonging to all $${L^{p}}$$Lp spaces, $${1\leq p < \infty}$$1≤p<∞. We obtain new results on strong convergence of Fourier series for functions of generalized bounded variation.
AIM To evaluate the effect of introducing a structured online follow-up system on the response rate. METHODS Since June 2015 we have set up an electronic follow-up system for prosthesis in orthopedic patients. This system allows prospective data gathering using both online and paper questionnaires. In the past all patients received questionnaires on paper. This study includes only patients who received elbow arthroplasty. Response rates before and after introduction of the online database were compared. After the implementation, completeness of the questionnaires was compared between paper and digital versions. For both comparisons Fisher’s Exact tests were used. RESULTS A total of 233 patients were included in the study. With the introduction of this online follow-up system, the overall response rate increased from 49.8% to 91.6% (P < 0.01). The response rate of 92.0% in the paper group was comparable to 90.7% in the online group (P > 0.05). Paper questionnaires had a completeness of 54.4%, which was lower compared to the online questionnaires where we reached full completeness (P < 0.01). Furthermore, non-responders proved to be younger with a mean age of 52 years compared to a mean age 62 years of responders (P < 0.05). CONCLUSION The use of a structured online follow-up system increased the response rate. Moreover, online questionnaires are more complete than paper questionnaires.
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