Background: There have been only a small number of studies that have evaluated the outcome of post-stroke delirium. Objectives: To evaluate the effects of gender, age, stroke localization, delirium severity, previous illnesses, associated medical complications on delirium outcome as well as, to determine effects of delirium on cognitive functioning one year after stroke. Patients and Methods: Comprehensive neuropsychological assessments were performed within the first week of stroke onset, at hospital discharge, and followed-up for 3, 6 and 12 months after stroke. We used diagnostic tools such as Glazgow Coma Scale, Delirium Rating Scale, National Institutes of Health Stroke Scale and Mini-Mental State. Results: Patients who developed post-stroke delirium had significantly more complications (p = 0.0005). Direct logistic regression was performed to assess the impact of several factors on the likelihood that patients will die. The strongest predictor of outcome was age, mean age ≥ 65 years with a odds ratio (OR) 4.9. Cox’s regression survival was conducted to assess the impact of multiple factors on survival. The accompanying medical complications were the strongest predictor of respondents poore outcome with Hazard-risk 3.3. Cognitive assessments including Mini Mental State score have showen that post-stroke delirium patients had significant cognitive impairment, three (p = 0.0005), six months (p = 0.0005) and one year (p = 0.0005) after stroke, compared to patients without delirium. Conclusion: Patient gender, age, localization of stroke, severity of delirium, chronic diseases and emerging complications significantly affect the outcome of post- stroke delirium. Delirium significantly reduced cognitive functioning of after stroke patients.

UDK 631.4:632.954; 633.1:632.954(497.6) The aim of the study is to present the elements which must be considered while determining the risk of the mobility of the herbicides. Herbicides used for maize production have the special eco toxical significance and special risk because some are potentially mobile, they are used on the large surfaces during the rainy period and near rivers. Behaviour of the herbicides in the environment, particularly in the soil is very complex. It does not depend only on the characteristics of the herbicide, but on the many factors of the environment which are very variable. Regardless of this fact, there are experimentally determined physical-chemical indicators for each herbicide that show the possible behaviour of herbicides in the environment. Studied physical-chemical indicators of herbicide behavior are: Distribution Coefficient (Kd); Organic Carbon Partitioning Coefficient (Koc); Time of the Semi-Decomposition (DT50); Water Solubility (S); Groundwater Ubiquity Score (GUS); Henry's Law Constant (Kh), Vapor Pressure (PV) and the Dissociation Constant (pKa). Namely, herbicides, in larger or smaller measure, have “leaching potential“, which is ability to reach the underground water. One of the basic criteria for evaluating the herbicide ability to reach the underground water is related to indicators of mobility and persistency (DT50) herbicides, but neglecting some other criteria in that evaluation such as the amount of applying, characteristics of the soil and the aim of the crop growth. According to the EPA criteria, for the herbicides used in maize production in Bosnia and Herzegovina (BiH), the “trigger“ value will indirectly indicate if the herbicides have large leaching potential.

UDK 631.41(497.6) The research was conducted on deposol and rekultisol (technosols) in lignite mine Stanari. The main task of the formed grasslands is to improve the mechanical, chemical and biological properties of the rekultisol and deposol in the reclamation process. The fertility of Stanari deposol is extremely low in comparison to the natural soil. Grassland seeding through direct type of reclamation was conducted in 2008, 2011 and 2012 year. The conducted researches include the changes in the adsorption complex in the surface layer of the treated deposol in the reclamation process. Laboratory analysis of this technogenic soil were carried out before the reclamation and sowing started, and then in the process of reclamation at the end of 2012. On the experimental plots where reclamation measures were implemented, there is a slight improvement in most of the chemical characteristics of the rekultisol. Adsorption capacity and saturation degree of base cations in rekultisol were increased. Proper selection of the agromeliorative and other measures is required in the reclamation process. Well based seeding grasslands contribute to the creation of quality rekultisol.

UDK 631.427.1(497.6) This paper studied the number of physiological and systematic groups of microorganisms in rekultisol under the different cultures at Stanari Coal Mine, and in variants of rekultisol where mineral fertilization and calcification were applied and in variants of rekultisol where only mineral fertilization was applied. The trial was set in the field conditions at the location of the internal part of overburden deposition site, near open pit Raskovac which is the part of Stanari coal mine. Mineral fertilizers were used as starter fertilizer and supplementary nutrition in the amount of 100-140 kg/ha of N and 40-60 kg/ha P2O5 and K2O and calcification was completed by adding 4 t/ha CaCO3. Microbiological analysis of the rekultisol determined the total number of bacteria, Azotobacter sp., ammonifiers, oligonitrophyls, actinomycetes and fungi. The aim of the research is to determine microbiological properties of rekultisol under small grains, potatoes, and grass-clover mixture at “Stanari” coal mine as well as to determine the effect of mineral fertilizers and calcification on the number of microorganisms in the rekultisol under different cultures. The total number of bacteria, oligonitrophyls, sporogenic ammonifiers, Azotobacter sp. and actinomycetes was higher in rekultisol under all of the tested cultures in the variant fertilizers + CaCO3 comparing to the variant without CaCO3, while the number of ammonifiers and fungi in rekultisol under all of the tested cultures was higher in the variant without CaCO3 in relation to the variant mineral fertilizers + CaCO3. In rekultisol under grass-clover mixture, higher total number of bacteria, oligonitrophyls and fungi was recorded in both tested variants, in relation to their number in rekultisol under potatoes and small grains. The number of actinomycetes was higher in rekultisol under potato in both variants, in relation to the number of actinomycetes in rekultisol under small grains and grass clover mixture. In rekultisol under small grains in variant mineral fertilizers + CaCO3 number of ammonifiers was the lowest (182 x 104g-1 absolutely dry soil), while the highest number of ammonifiers was recorded in rekultisol under grass-clover mixture in the variant without CaCO3 (1778 x 104g-1 absolutely dry soil). Azotobacter sp. count was lowest in rekultisol under grass clover variant without CaCO3 (68 x 102g-1 absolutely dry soil), while the highest Azotobacter sp. count was recorded in rekultisol under small grains in the variant with fertilizers + CaCO3 (123 x 102g-1 absolutely dry soil).

Objectives: To determine the incidence of brain edema after ischaemic stroke and its impact on the outcome of patients in the acute phase of ischaemic stroke. Patients and Methods: We retrospectively analyzed 114 patients. Ischaemic stroke and brain edema are verified by computed tomography. The severity of stroke was determined by National Institutes of Health Stroke Scale. Laboratory findings were made during the first four days of hospitalization, and complications were verified by clinical examination and additional tests. Results: In 9 (7.9%) patients developed brain edema. Pneumonia was the most common complication (12.3%). Brain edema had a higher incidence in women, patients with hypertension and elevated serum creatinine values, and patients who are suffering from diabetes. There was no significant correlation between brain edema and survival in patients after acute ischaemic stroke. Patients with brain edema had a significantly higher degree of neurological deficit as at admission, and at discharge (p = 0.04, p = 0.004). Conclusion: The cerebral edema is common after acute ischaemic stroke and no effect on survival in the acute phase. The existence of brain edema in acute ischaemic stroke significantly influence the degree of neurological deficit.

Introduction: Non Hodgkin lymphoma-Diffuse large B cell lymphoma (DLBC) is composed of more varieties of one disease. Analysis and understanding of a wide range of characteristics of the disease, which include: clinical, immunohistochemical, cytogenetic and molecular characteristics may improve treatment results. Aim: achieving the estimated three-year survival and influence of IRF/MUM1 expression to three-year survival. Material and methods: A study was retrospective–prospective, patients were followed for seven years a period of dine. The study included 60 patients de novo DLBCL. Age was 18-72 years old, the average age 45 years, male 31 (51,7%) and female 29 (48.3%). Median follow-up was 47 months (3-91 months). To determine differentiation immunophenotype antibodies those were used anti-CD20, anti-CD10, anti-Bcl-6, IRF-4/MUM1, CD 138. Results: Included the GCB type was 65%. Impact prognostic index IPI>2 GBC vs non GBC p=0,038 X2. Statistically significant difference was confirmed compared to the IPI> 2 to 3 year OS p<0,0005 X2. Significantly longer three-year survival was provided in the group GCB 36 (92,3%) vs. non GCB 8 (38,1%) p=0,003 X2. Clinical and immunohistochemical factors showed a significant impact to three-year survival by univariate: LDH p=0,005, MUM1 p=0,003, while CD10 p=0,069 was confirmed on the level of borderline impact. Using multivariate analysis, expression MUM1 has the greatest impact p<0.0005 OR=0.083 (95% CI 0.23-0.303) on the disease outcome – three-year survival. Conclusion: expression MUM1 >25% has the greatest impact on the disease outcome – three-year survival.

Introduction: The objective of this study was to determine the oral health condition Down syndrome (DS) children in Bosnia and Herzegovina, by analizing oral health of Down syndrome individuals in two largest regions, Sarajevo and Tuzla Canton. Patients and Methods: Caries and oral health status of Down syndrome children aged 6-18 years were examined and assessed according WHO 1997 criteria. DS individuals were divided in to four age groups: I (0-6 yrs); II (7-12 yrs); III (13-18 yrs). Results: The mean dmft/DMFT index for age group I is (6,40±6,05); II (2,05±2,04) and III (10,30±6,80). The analysis of oral hygiene of Down syndrome children by using the debris index, it was found that 43,9% have very good oral hygiene, 33,3% respondents have good oral hygiene, 15,8% were with poor oral hygiene, while the very poor hygiene had 7% subjects. By using Pearson’s correlation to the value of DMFT, debris index and age of examinees with Down syndrome, it is established a statistically significant positive correlation between analyzed variables. Values of CPI index according to age groups were as follows: I (0,1); II (0,17) and III group (0,4).

Introduction: Surgical and medical treatments of nasal obstruction are a common parts of otolaryngologist practice. The definitive treatment of deviated nasal septum is septoplasty. Aim: In this study was to evaluate the values of subjective parameters, and active anterior rhinomanometry parameters prior and three months after the septoplasty. Patients and Methods: We analyzed the subjective parameters (“NOSE” scale), the active anterior rhinomanometry parameters according to International Committee on Standardization of Rhinomanometry, on 40 patients. Thirty healthy adult volunteers participated belonged to the control group. None of the patients or healthy volunteers had previous history of nasal surgery or active rhinological disease. Results: The post-operative improvement in symptoms of nasal obstruction obtained in 92,5% patients and improvement parameters of the active anterior rhinomanometry in 42,5% patients. Conclusion: The correlation between the findings with rhinomanometry and subjective sensation of nasal patency remains uncertain. There still seems to be only a limited argument for the use of rhinomanometry for quantifying surgical results. Three months postoperative findings are very early results to interpret the permanent effects.