The control of recently observed spintronic effects at topological-insulator/ferromagnetic-metal (TI/FM) interfaces is thwarted by the lack of understanding of their band structure and spin texture. Here we combine density functional theory with Green's function techniques to obtain the spectral function at any plane passing through atoms of Bi$_2$Se$_3$ and Co or Cu layers comprising the interface. In contrast to naively expected Dirac cone gapped by the proximity exchange field, we find that the Rashba ferromagnetic model describes (for some range of momenta) the spectral function on the surface of Bi$_2$Se$_3$ in contact with Co near the Fermi energy $E_F^0$, where circular and snowflake-like constant energy contours coexist around which spin locks to momentum. Interestingly, similar in-plane spin textures are also injected into first three monolayers of Co adjacent to Bi$_2$Se$_3$ due to spin-orbit proximity effect. The remnant of the Dirac cone is hybridized with evanescent wave functions injected by metallic layers and pushed, due to charge transfer from Co or Cu layers, few tenths of eV below $E_F^0$ for both Bi$_2$Se$_3$/Co and Bi$_2$Se$_3$/Cu interfaces while hosting distorted helical spin texture wounding around a single circle. These features can explain recent observation [K. Kondou et al., Nat. Phys. 12, 1027 (2016)] of extreme sensitivity of spin-to-charge conversion signal at TI/Cu interface to tuning of $E_F^0$. We predict that tunneling anisotropic magnetoresistance in vertical heterostructure like Cu/Bi$_2$Se$_3$/Co, where current flowing perpendicular to its interfaces is modulated by rotating magnetization from out-of-plane to in-plane direction, can be employed to probe the type of spin texture residing at $E_F^0$ via purely charge transport measurement.

ABSTRACT The thermal power plant systems are one of the most complex dynamical systems which must function properly all the time with least amount of costs. More sophisticated monitoring systems with early detection of failures and abnormal behaviour of the power plants are required. The detection of anomalies in historical data using machine learning techniques can lead to system health monitoring. The goal of the research is to build a neural network-based data-driven model that will be used for anomaly detection in selected sections of thermal power plant. Selected sections are Steam Superheaters and Steam Drum. Inputs for neural networks are some of the most important process variables of these sections. All of the inputs are observable from installed monitoring system of thermal power plant, and their anomaly/normal behaviour is recognized by operator's experiences. The results of applying three different types of neural networks (MLP, recurrent and probabilistic) to solve the problem of anomaly detection confirm that neural network-based data-driven modelling has potential to be integrated in real-time health monitoring system of thermal power plant.

ABSTRACT This paper builds on the general survey of post-mortem privacy set out in the author’s earlier work. The concept of post-mortem privacy is further developed both at a theoretical level (underpinned by theories of autonomy) and a doctrinal level (considering concepts such as testamentary freedom, and the protection of personal data). Finally, the paper looks at some current developments of technology (tech solutions for the protection of post-mortem privacy) and law/policy (work done by the US Uniform Law Commission on the Uniform Fiduciary Access to Digital Assets Act – UFADAA). The argument is that both of these regulatory modalities provide examples and illustrations of how post-mortem privacy can be recognised practically, especially in the online environment. The paper is, therefore, setting the scene further in this under-explored area, also aiming to set the basis for the author’s subsequent empirical research (attitudes towards post-mortem privacy, quantitative and qualitative).

The University of Pittsburgh's Department of Biomedical Informatics and Division of Pathology Informatics created a Science, Technology, Engineering, and Mathematics (STEM) pipeline in 2011 dedicated to providing cutting-edge informatics research and career preparatory experiences to a diverse group of highly motivated high-school students. In this third editorial installment describing the program, we provide a brief overview of the pipeline, report on achievements of the past scholars, and present results from self-reported assessments by the 2015 cohort of scholars. The pipeline continues to expand with the 2015 addition of the innovation internship, and the introduction of a program in 2016 aimed at offering first-time research experiences to undergraduates who are underrepresented in pathology and biomedical informatics. Achievements of program scholars include authorship of journal articles, symposium and summit presentations, and attendance at top 25 universities. All of our alumni matriculated into higher education and 90% remain in STEM majors. The 2015 high-school program had ten participating scholars who self-reported gains in confidence in their research abilities and understanding of what it means to be a scientist.

The University of Pittsburgh's Department of Biomedical Informatics and Division of Pathology Informatics created a Science, Technology, Engineering, and Mathematics (STEM) pipeline in 2011 dedicated to providing cutting-edge informatics research and career preparatory experiences to a diverse group of highly motivated high-school students. In this third editorial installment describing the program, we provide a brief overview of the pipeline, report on achievements of the past scholars, and present results from self-reported assessments by the 2015 cohort of scholars. The pipeline continues to expand with the 2015 addition of the innovation internship, and the introduction of a program in 2016 aimed at offering first-time research experiences to undergraduates who are underrepresented in pathology and biomedical informatics. Achievements of program scholars include authorship of journal articles, symposium and summit presentations, and attendance at top 25 universities. All of our alumni matriculated into higher education and 90% remain in STEM majors. The 2015 high-school program had ten participating scholars who self-reported gains in confidence in their research abilities and understanding of what it means to be a scientist.

An important task in conducting a systematic review is reading titles and abstracts of the retrieved references, which often number in the thousands, to determine which articles meet the predefined inclusion criteria. In the past, this was performed by manually scanning through large stacks of printed titles and abstracts, followed by face-to-face meetings to discuss which references should be included. Today, the workflow of the review process is more streamlined by using computer software.

ABSTRACT Plant biostimulants are substances which have the capacity to modify physiological processes in plants in a way that provides potential benefits to growth, development or stress response. Effects of biostimulant application on two tomato hybrids (Ombeline F1 and Bostina F1) submitted to reduced nitrogen, phosphorus and potassium (NPK) nutrition aiming at prevention of oxidative stress generation as well as yield and fruit quality loss were investigated in this study. According to obtained results, foliar applied Viva® biostimulant decreased superoxide dismutase (SOD, EC 1.15.1.1) and peroxidase (POD, EC 1.11.1.7) activity in tomato leaves even when recommended NPK nutrition was reduced at 40%. Fruit quality parameters (total soluble solids, total acidity, ascorbic acid and lycopene content) and yield were also maintained in reduced macronutrient fertilization when biostimulant was added. Combination of biostimulant with reduced NPK fertilizer enabled stability of cell homeostasis in tomato plants and their better adaptation to stress conditions. The possibility of biostimulant being used as environmental friendly tool in the reduction of mineral fertilizers without negative consequences regarding yield and fruit quality was discussed.

Introduction Fractures of the radial head and neck are the most common fractures of the elbow, and account for approximately one-third of all elbow fractures. Depending on the fracture type the treatment is either conservative or surgical. There is no absolute consensus regarding optimal treatment for different fracture types. The aim of this protocol is to present the method that will be used to collect, describe and analyse the current evidence regarding the treatment of Mason II–III radial head and neck fractures. Method and analysis We will conduct a systematic review in accordance with the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocol (PRISMA-P) guidelines statement. We will search a number of databases with a predefined search strategy to collect both randomised and non-randomised studies. The articles will be summarised with descriptive statistics. If applicable a meta-analysis will be conducted. Ethics and dissemination Ethical approval is not required since this is a protocol for a systematic review and no primary data will be collected. The authors will publish findings from this review in a peer-reviewed scientific journal. Trial registration number CRD42016037627.

ABSTRACT Foraging theory suggests organisms increase their fitness through dietary and energetic choices. In nature, organisms choose to consume balanced optimal diets but as exotic plants invade ecosystems, new foraging options become available. Often these plants have different traits and can negatively affect fitness of foragers by lowering survival or growth due to toxicity. Wetland habitats are highly susceptible to plant invasions which can have negative effects on nutrient cycling. The purpose of this study was to examine whether invasion of purple loosestrife (Lythrum salicaria) alters tadpole foraging preference thus potentially impacting their survivorship and fitness. We designed a common garden experiment and utilized stable isotopic signatures to investigate the contribution of purple loosestrife and native hardwood detritus to larval wood frog (Rana sylvatica) and southern leopard frog (Rana sphenocephala) diets. Tadpoles derived a higher percentage of resources from purple loosestrife compared to native hardwood detritus when presented with both options, despite its high concentration of toxic secondary compounds. It is unknown if tadpoles can detect competing fitness signals that may be associated with higher nutrient and toxicity levels in purple loosestrife. Discovering the presence or absence of such signals will promote a greater understanding of selective foraging in changing environments.

Abstract The cytotoxic activity of phenylboroxine acid was evaluated in vitro on mouse mammary adenocarcinoma 4T1, mouse squamous cell carcinoma SCCVII, hamster lung fibroblast V79 and mouse dermal fibroblasts L929 cell lines. The cytotoxic effects were dose dependent for all tested tumour and non-tumour cell lines. Under in vivo conditions, three application routes of phenylboronic acid were studied: intra-peritoneal (i.p.), intra-tumour (i.t.) and per-oral. After tumour transplantation in syngeneic mice, phenylboronic acid was shown to slow the growth of both tumour cell lines (4T1 and SCCVII) compared with the control. The inhibitory effects were pronounced during the application of phenylboronic acid. For both tested tumour cell lines, the most prominent antitumour effect was obtained by intraperitoneal administration, followed significantly by oral administration.