antineutrophil cytoplasmic autoantibody (anca)-associated vasculitis (aav) is a small-vessel vasculitis, characterized by necrotizing inflammation of small vessels and positive ancas. cancas are directed against proteinase-3 (Pr-3) and are specific for granulomatosis with polyangiitis (GPa, formerly known as Wegener’s disease), although their role in the immunopathology of the disease is still unclear. This is why the european medicines agency suggested that canca positivity, in addition to the clinical picture, can be enough for the diagnosis of GPa. Granulomatosis with polyangiitis is characterized by granulomatous inflammation that usually involves the upper and lower respiratory tract, necrotizing vasculitis that affects small and medium-sized vessels, and often rapidly progressive glomerulonephritis. We present a patient with an unusual presentation of canca-associated vasculitis, who presented with arthritis, palpable purpura on legs, and pauci-immune necrotizing glomerulonephritis with highly positive canca antibodies, without any signs or symptoms of airway involvement. although renal-limited anca vasculitis is recognized as a separate entity, our patient also had signs of skin and joint involvement and prominent constitutional symptoms that contributed to the diagnosis of systemic disease. in this paper, we present a patient with an atypical course of GPa, which can also be called a limited form of the disease. an atypical course or limited form belongs to the group of sine syndromes in inflammatory rheumatic diseases, which are not very common, but should be considered in the differential diagnosis. to our knowledge, there are only a few described case reports with a similar presentation.
In the present work, by using a paralelepipedic thermogravitational microcolumn, the temperature gradient influence on the stability of the flow was or has been examined, emphasizing mixtures with negative Soret coefficients. Experiments and numerical analysis were conducted for DCMIX2 Toulene-Methanol binary subsystem. This binary subsystem has a broad range of negative Soret values for low concentrations of Methanol which was analysed. Two different concentrations have been studied in order to confirm existence of temporal stability windows of those mixtures. Experiments were compared with numerical simulations conducted in open source software OpenFOAM, for both cases.
This article presents an improved equity momentum measure for corporate bonds, using the euro-denominated global investment-grade corporate bond market from 2000 to 2016. The author documents economically meaningful and statistically significant corporate bond return predictability. In contrast to the widely used total equity return, momentum as measured by the residual (idiosyncratic) equity return appears to further enhance risk-adjusted performance of corporate bond investors. Additional support for this conjecture is obtained from tests for various asset pricing factors and transaction costs, as exposure to these risk factors cannot explain this abnormal pattern in returns.
<p style="text-align: justify;">3D printing is a technology that is increasingly used in many engineering fields and education. This technology is primarily used in rapid prototyping and rapid tooling. In this paper the geometrical accuracy of FDM (Fused Deposition Modelling) 3D printing is presented. For the dimensional test process, a 3D model which contains the characteristic geometrical shapes and dimensions that were used as a reference for measuring on the<br />coordinate measurement machine, has been created. The CAD model was created in SolidWorks software, the model was printed on the Ultimaker 2+ 3D printer and the measurement has been proceeded on the Zeiss Contura G2 coordinate measuring machine.</p>
<p style="text-align: justify;">This paper describes the application of international standards, recommendations and guides, as well as other input data, to determine the interval of recalibration of laboratory equipment in the laboratory for testing the product safety testing LIND in Zenica, Bosnia and Herzegovina. An example of a pressure sensor on a 4-axis device for measuring the geometry of furniture, a detailed analysis of the recalibration interval was performed, which had to be shortened from 5 to 3 years.</p>
<p style="text-align: justify;">Contraction is a part of a wind tunnel that has the greatest impact on the air flow quality in the test section. The constriction ratio, the cross section shape, the length and wall shape are constructive parameters that influence the uniformity of the flow, the flow turbulence intensity, the flow rotation angularity, the appearance of the flow separation and the thickness of the fluid flow boundary layer in the test section. For this reason, it is very<br />important to choose the optimal combination of the mentioned contraction design parameters. In this paper, an analysis of five different contours of the contraction wall was performed for the square outlet cross-section Ao=0.64 m2, the constriction ratio CR=4 and the contraction length L=1.88 m. With the computer code of Flow Simulation, 25 numerical simulations were performed and the obtained results were analyzed.</p>
Surveying is an undisputed link in the chain of professions that participate in the realization of projects for the construction of various buildings and structures. Different stages of construction require the engagement of geodesists in a different range. The process of construction of the pillar of the viaduct "Briješće" required the collaboration of a large number of experts of various profiles, among which is a geodetic expert. The paper contains a detailed description of geodetic works in the construction of the viaduct pillar, starting from the establishment of the control network to the final control of the pillar construction.
<p style="text-align: justify;">Cranioplasty is the surgical repair of a bone defect in the skull that is left behind after a severe injury or previous operation. It is usually done to protect underlying brain tissue, reduce local pain and to improve the cranial vault aesthetics. Cranial prostheses can be made from different types of materials: autologous bone, titanium, ceramics and polymers. Their production is costly and often requires complex intraoperative processes which sometimes cause poor aesthetic results in large and complex defects. Using a real case, this paper presents a customised polymethyl methacrylate implant production method which involves three dimensional reconstruction based on CT scans, technology of 3D printing and moldmaking<br />from dental plaster.</p>
Nowadays remote sensing is an indispensable source of information about Earth's surface, primarily satellite-based remote sensing systems. Traditionally, the analysis of data collected from a particular area was based on the analysis of the data of one satellite image. The technological revolution improved spatial, temporal and radiometric resolution of satellite images, which allowed time datasets analysis, combining (integrating) data from various sensors, combining images of different scales and better integration with existing data and models. The integration of data from different sources is becoming an increasingly important factor in numerous aspects of remote sensing, and the results of this technique are used in solving everyday problems.
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