Aim: Aim of the article was to present a case of post transplantation invasive aspergillosis, successfully treated with conservative and surgical treatment. Case report: Patient, male, 44 years old, with second kidney transplant, required special preparation therapy, because he was sensitized, with concentration of Panel Reactive Antibody (PRA) class I 11% and PRA class II 76%. On the day of transplantation, induction was done with anti-thymocyte globulin (ATG) and glucocorticosteroids. After transplantation, plasmapheresis with ATG was performed. On the fourth day patient was anuric. Fine-needle biopsy of the graft was performed and showed positive CD4 antibodies for peritubular capillaries and humoral rejection. 14 plasmaphereses through 14 days, were negative and ATG treatment was suspended completely. Full therapeutic dosage of tacrolimus and mycophenolate mofetil were given during treatment. Four days after treatment patient was stable, but next day clinical status had worsened with dyspnea and fever. In sputum, spores of Aspergillus species were microscopically found, and radiologically by computerised tomography. Caspofungin was administered for seven days. Voriconazole therapy was given for first ten days by intravenous route and after then orally. Even with this treatment, there was no improvement in clinical picture, while CT scan of the lungs showed abscess collection in right lung. Lobectomy was performed and pus collection was found. After graft-nephroctomy, patient was treated with continous veno-venous hemodiafiltration (CV-VHDF) dialyses, with constant voriconazole therapy for the next three months (200mg two times per day). After one month of diagnosis, Galactomannan (GM) test was negative. Conclusion: Although highly sensitized patients, those who are on hemodialysis, in preparation for transplantation, receive intensive immunosuppressive therapy that suppress the immune system. Occurrence of secondary fungal infections especially infection by aspergillosis, is cause of high mortality of infected. Application GM test that detects existence of antibodies against Aspergillus antigens and usage of different type of immunosuppressive preparation can increase longevity of graft and patients in solid organ transplantation program. Aspergillosis is treated with voriconazole and surgery, and sometimes graft-nephrectomy if needed. Recommendation is that in all immunocompromised hosts and organ transplant recipient should have been tested with GM test.
UDK: 630*36:631.372]:65.015(497.6) This paper presents the research results of the skidding productivity for the Ecotrac 120V skidder in mountainous areas of MU „Igmanˮ in Bosnia and Herzegovina. Time and work study were performed. Multiple regression analysis was used for determination of work operations time consumption depending on influencing factors. The following influencing factors were recorded: the condition of the tractor road (surface), the skidding distance, the winching distance, number of pieces in the load, the volume of the load and the slope of the tractor road. The share of productive time in the total work time is 58.47%. The average value of the influencing factors was established: unloaded travel distance 585.26 m, loaded travel distance 490.49 m, winching distance 16.83 m, number of pieces in the load 5.95, the volume of the load 5.17 m3 and the volume of the piece in the load 1.02 m3. The half-tree length method was used. Standard time for skidding and daily skidding productivity were expressed depending on the skidding distance, while average values were used for other influencing factors. The standard time for skidding was 6.57 min/m3 at a skidding distance of 100 m, i.e. 17.60 min/m3 at a skidding distance of 1,500 m. The daily skidding productivity ranges from 73.07 m3/day at a skidding distance of 100 m to 27.28 m3/day at a skidding distance of 1,500 m. Comparison of the daily skidding productivity with the results of other researches showed that the Ecotrac 120V skidder in this particular case realizes approximately the same skidding productivity under similar working conditions.
Introduction: In patients with acute myocardial infarction (AMI) early risk assessment of development of complications is of great importance. It is proven that aldosterone level has a major role in progression of cardiovascular pathology. Aim: Determination of influence of aldosterone plasma level in the progression of heart disease in patients without signs of heart failure after AMI. Material and Methods: Research included 207 patients, hospitalized in the acute phase of myocardial infarction, and who were divided into two groups: 127 patients with no clinical signs of heart failure and 60 patients with heart failure. Results: The serum aldosterone concentration was 73.4% higher in the group of decompensated patients, 128 pg/mL (75.4-236 pg/mL) in decompensated and 73.7 pg/mL (42.7 -115.25 pg/mL) in compensated. In the group of compensated patients, changes in aldosterone levels showed a statistically significant effect on the incidence of post-infarction angina (p=0.0001) as well as reinfarction (p=0.009). There is a connection between changes in aldosterone plasma level and positive stress test (p=0.012). Conclusion: In patients with AMI, elevated serum aldosterone level can be prognostic factor of the progression of coronary heart disease, development of heart failure, as well of development of post-infarction angina, myocardial reinfarction and pathological finding on the stress test.
This work was carried out antimicrobial effect on seed dill. The survey was done by diffusion dilution method. By using MVC
Recent advances in the development of wearable sensors and smartphones open up opportunities for executing computing operations on the devices instead of using them for streaming raw d ...
This is a preprint of a chapter accepted for publication by Facet Publishing. This extract has been taken from the author’s original manuscript and has not been edited. The definitive version of this piece may be found in 'Partners for Preservation: Advancing digital preservation through cross-community collaboration' Facet, London, 9781783303472 which can be purchased from http://www.facetpublishing.co.uk/title.php?id=303472#about-tab
The problem of environmental pollution is more expressed and more present by the development of the industry and the growth of the human population. Pollution of natural and wastewater is most often due to the release of heavy metals into watercourses. The greatest challenge for researchers is choosing the right biomass from a large number of low-cost biomaterials, and availability and price are very important selection factors. Microbial biomass, forestry waste and agroindustrial complexes are most frequently examined, as well as various macromolecules of natural origin. In this paper, barley straw that arises as agricultural waste product in barley production in Bosnia and Herzegovina, was used as a biosorbent. In the experimental part, physical and chemical characterization of barley straw was performed, after which the efficiency of removing Cd(II) and Ni(II) from aqueous solutions, using barley straw, and the influence of process parameters (pH value of aqueous solution, biosorbent size, interaction of metal ions) on the biosorption capacity were tested. It can be concluded that barley straw has good adsoption characteristics for the use as a low-cost natural sorbent for the removal of heavy metals from water.
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