Klir-Yuan fuzzy implication, as fuzzy implication generated from the standard strong fuzzy negation, the probabilistic sum t-conorm, and the product t-norm, represents a classical example of QL-implication, where QL-implications are the short for quantum logic fuzzy implications. In this paper we prove that the recent results on equivalences between fuzzy formulas and fuzzy dependencies remain invariant with respect to QL-implications when considered through Klir-Yuan fuzzy implication.

In this paper we complement the most recent results on soundness of inference rules for new vague multivalued dependencies. Motivated by the fact that the inclusive and the augmentation rules are sound, we prove that: complementation, transitivity, replication, coalescence, union, pseudo-transitivity, decomposition, and mixed pseudo-transitivity rules are also sound. Our research relies on definitions of vague functional and vague multivalued dependencies based on appropriately selected similarity measures between vague values, vague sets, and tuples on sets of attributes.

This paper represents a natural continuation of our previous study. In our earlier research we proved that the inclusive inference rule and the union inference rule for new vague functional dependencies are sound, and sketched a proof of the fact that the set of the main inference rules is a complete set. In the present paper we rigorously prove that: reflexive, augmentation, transitivity, pseudo-transitivity, and decomposition inference rules are also sound. Some additional insights in completeness of the main inference rules are also provided.

The Editors’ Network of the European Society of Cardiology provides a dynamic forum for editorial discussions and endorses the recommendations of the International Committee of Medical Journal Editors (ICMJE) to improve the scientific quality of biomedical journals. Authorship confers credit and important academic rewards. Recently, however, the ICMJE emphasized that authorship also requires responsibility and accountability. These issues are now covered by the new (fourth) criterion for authorship. Authors should agree to be accountable and ensure that questions regarding the accuracy and integrity of the entire work will be appropriately addressed. This review discusses the implications of this paradigm shift on authorship requirements with the aim of increasing awareness on good scientific and editorial practices.

Abstract Education plays a central role in today’s understanding of growth and development dynamics. However, its relationship with other factors is complex. This paper aims to investigate the effect of different forms of education on youth employability in Bosnia and Herzegovina. This is done by using the USAID MEASURE – BiH National Youth Survey. Research has shown that formal education and non-formal education through internship programmes, volunteering, paid jobs other than internships are significant predictors of youth employment status. The study also has several implications for academics and practitioners since it provides new insights into both employment patterns and practices in one transition economy but also calls for further analysis of the link between education, formal and non-formal, and youth employment.

Breast cancer is the second most common cause of cancer-related deaths among women worldwide. It is a heterogeneous disease with four major molecular subtypes. One of the subtypes, human epidermal growth factor receptor 2 (HER2)-enriched (HER2-positive) is characterized by the absence of estrogen and progesterone receptors and overexpression of HER2 receptor, and accounts for 15–20% of all breast cancers. Despite the anti-HER2 and cytotoxic chemotherapy, HER2 subtype is an aggressive disease with significant mortality. Recent advances in molecular biology techniques, including gene expression profiling, proteomics, and microRNA analysis, have been extensively used to explore the underlying mechanisms behind human breast carcinogenesis and metastasis including HER2-positive breast cancer, paving the way for developing new targeted therapies. This review focuses on recent advances on gene expression and miRNA status in HER2-positive breast cancer.

INTRODUCTION Chronic diseases with disabilities have a huge pharmacoeconomic impact on the health budget, especially in countries with recent history of social and economic transition. The aim of this study was to identify total costs of treating patients with lumbar pain in medical facilities in the central part of the Republic of Serbia. MATERIAL AND METHODS This study was designed as a cost of illness study, using a bottom-up approach and it was conducted from a societal perspective. This study included 97 patients with lumbar syndrome who were treated in outpatient facilities in the Central part of Serbia. RESULTS Total costs of treating lumbar pain were about €200.40 ± €86.65 per patient per year, where the largest volume of direct costs were costs due to visits to specialists in primary health care institutions (€9.39 ± €6.66). Total indirect costs were €182.00 ± €78.66. DISCUSSION Our findings highlight the need to estimate the total costs of treating lumbar pain and evaluate the correlation between costs and other variables for larger population of these patients. CONCLUSION This study distinguished two important pharmacoeconomic aspects of treating lumbar pain. Firstly, indirect costs represent major part of total costs of treating lumbar syndrome. Secondly, differences in valuing medical services between countries with recent history of social and economic transition and countries within European Union are one of crucial reasons for difference in total costs of treating low back pain among patients in neighboring regions.

Govedarstvo kao jedna od najznačajnijih grana stočarske proizvodnje se dugosuočava sa hroničnim problemom pada reproduktivnih performansi. U 2005 godini broj govedaširom svijeta je iznosio oko 1.370.000.000 grla, dok je u 2012 taj broj iznosio tek nešto iznadmilijarde, što govori o važnosti primjene različitih reproduktivnih protokola u cilju povećanjabrojnosti proizvodnih jedinki. Toplotni stres dovodi do poremećaja fizioloških i reproduktivnihprocesa, jer rast tjelesne temperature uzrokovan toplotnim stresom ima direktne negativne posljedicena brojne ćelijske funkcije. U istraživanje je bilo uključeno ukupno 54 krave Holštajn-Frizijskepasmine, 28 eksperimentalnih i 26 kontrolnih krava, uzgojenih na PD Butmir sa prosječnomiskoristljivošću od 5. laktacija. Hormonalni protokoli sinhronizacije estrusa i ovulacije su korišteniu mjesecima juni i juli 2013. godine. Krave u eksperimentalnoj grupi su podvrgavanepresynch+5dCoS2 hormonalnom protokolu. Krave koje nisu ostale gravidne nakon ovog protokolaodmah su podvrgnute resinhronizaciji sa hormonalnim protokolom Cosynch 72. Uspješnostpresynch+5dCoS2 hormonalnog protokola je bila 19%, dok je u slućaju Cosynch 72 ona iznosila33%, a što je bilo statistički signifikantno (p< 0,05). Prvi presinhronizacijski i sinhronizacijskiprotokol (5dCoS2) nisu značajnije pomogli u poboljšanju koncepcije nakon prvog osjemenjavanjapostpartum, ali na osnovu rezultata evidentno je da su imali pozitivni efekt na drugi protokol(COS72) u vidu smanjenja embrionalnog mortaliteta u ljetnim mjesecima, kada je on najizražajniji.Protokol COS72, daje zadovoljavajuće rezultate u ljetnom periodu, ali preduvjeti za uspješanprogram sinhronizacije estrusa i ovulacije uoči vještačkih osjemenjavanja su dobra kondicija izdravstveni menadžment, kao i smanjenje toplotnog stresa u skladu s lokacijom i dizajnom farme.

Utjecaj gljiva truležnica roda Heterobasidion i Armillaria na pojavu truleži na stablima obične smreke provedeno je na Šumskogospodarskom području “Gornjebosansko”, gospodarska jedinica “Gornja Stavnja”, odjeljenje 65. Utvrđivanje prisutnosti truleži vršeno je na srušenim stablima obične smreke na premjernim površinama koje su raspoređene u sistematski postavljenoj mreži 100 m x 100 m. Uzorci su prikupljeni sa tri mjesta na dijelu debla zahvaćenom procesom truleži (početak zone truleži, sredina i vršna zona truleži). Na mjestima uzorkovanja uzimani su kolutovi drva debljine 5 cm. Analize uzoraka su provedene u laboratorijima Šumarskog fakulteta Univerziteta u Sarajevu. Za izravnu izolaciju gljivične DNA su pripremljeni uzroci drva mase 10-20 mg. Za amplifikaciju ciljanog segmenta DNK korištene su tubice s pripremljenim reagensima, proizvod ReadyToGo PCR beads tvrtke Amersham, Bioscience. Za amplifikaciju ciljanog segmenta ITS regije za rod Heterobasidion su korišteni početnice MJ-F, MJ-R, KJ-F i KJ-R, pomoću kojih je utvrđena međuvrsna raznolikost (tablica 2). Za amplifikaciju ciljanog segmenta ITS regiona za rod Armillaria su korišteni početnice ITS-1 i ITS-4, pomoću kojih je utvrđena samo pripadnost rodu. Za međuvrsnu raznolikost je vršena amplifikacija ciljanog segmenta IGS regiona za rod Armillaria pomoću početnice LR12 i O-1, te razgradnja endonukleazom AluI (tablica 3). Uspješnost amplifikacije je provjerena elektroforezom na agaroznom gelu. Interpretacija profila je izvršena pomoću molekularnog markera poznate veličine (100 bp) (slika 1). Na osnovi provedenih istraživanja unutar istraživane sastojine utvrđeno je 9 stabala s gljivom H. parviporum, 2 stabla s gljivom A. ostoyae, 1 stablo s gljivom A. cepistipes, te 17 stabala čiju trulež su uzrokovale ostale gljive truležnice (tablica 4). Gljiva H. annosum je uspješno identificirana iz plodišta. Na osnovi svega navedenog, može se zaključiti da je molekularnim analizama moguće utvrđivati međuvrsnu raznolikost gljiva ova dva roda iz uzoraka drveta sa truleži i plodišta gljiva.