Introduction. The harmful effect of cigarette use has been proven through existing studies, but the recent advanced use of heat-not-burn-tobacco-products (HNB) and its effect remains under observation. Results. After six months, HNB users exhibited better-preserved FEV1 and peripheral oxygenation values. Conclusion. Patients using HNB tobacco products achieved better 6MWT and spirometry testing results and showed lower cholesterol and hs-CRP levels after six months of follow-up. Keywords: smoking, spirometry, heat-not-burn, lung function decline, respiratory health.

Freedom of contract is a fundamental principle of obligation law, but in modern legal systems it functions as a relative and normatively oriented category. The paper examines the theoretical foundations of this institute, starting from the liberal conceptual core of the autonomy of the will and its historical development, to the modern, functional concept that views contractual freedom in the broader framework of public law restrictions, market discipline, and protection of the weaker party. The analysis includes domestic and comparative law, including standards of European contract law and modern economic indicators (EFW index), in order to indicate the connection between economic and contractual freedom. Special attention is paid to the position of business entities, where contracting has a specific dimension due to their professional status, the complexity of market transactions, and pronounced information asymmetry. Through the analysis of imperative norms, standard and adhesion contracts, regulated markets, and unequal bargaining power, the key practical and systemic limits of business autonomy are pointed out. The results of the work show that these restrictions do not represent a negation of the freedom of contract, but a mechanism for its functional realization - through the provision of legal certainty, fair market conditions, protection of competition, and stability of the economic order. The paper contributes to a better understanding of the modern conception of contractual autonomy in the economy, indicating that the balance between freedom of disposition and public law regulation is the key assumption of an efficient, fair, and sustainable contractual system.

Izgradnja poslovne infrastrukture, naročito poslovnih zona, podrazumijeva ispunjenje cijelog niza pretpostavki koje su često međusobno uslovljene. U vezi s tim u bosanskohercegovačkom pravnom okviru do izražaja dolaze brojni faktori ustavnopravne, ali i stvarnopravne prirode. Najprije treba poći od činjenice složenosti ustavnog sistema u Bosni i Hercegovini, gdje se moraju uvažiti legislativne postavke, naročito u dijelu nadležnosti za uređenje određene oblasti. Tako, kad je riječ o izgradnji poslovnih zona, posebno mjesto imaju jedinice lokalne samouprave, ali s bitno promijenjenom ulogom u odnosu na period u okviru bivše države (SFRJ). Zapravo, u odnosu na raniji (socijalistički) period, kada su jedinice lokalne samouprave imale gotovo ključnu uloge u smislu planiranja te izgradnje proizvodnih kompleksa, danas imaju bitno drugačiji položaj, koji se u pravilu svodi na planiranje prostornih obuhvata budućih poslovnih zona te na izdavanje potrebnih dozvola. To je rezultat napuštanja komandne privrede u okviru koje je izgradnja proizvodnih kompleksa vezana za državnu regulaciju. Dakle, rezultat tranzicijskih procesa u ovoj oblasti rezultirao je situacijom da je proces izgradnje poslovnih zona iz javnopravnog sektora prešao isključivo u privatnopravnu sferu, gdje ključnu ulogu imaju privatni investitori, dok jedinice lokalnih samouprava imaju servisnu ulogu. Upravo je saradnja između javnopravnih subjekata, pri čemu se dominantno misli na jedinice lokalne samouprave, i potencijalnih investitora, ključni segment u smislu da li će se uopće izgraditi određena poslovna zona. U tom odnosu, pored ustavnopravnog okvira, od izuzetnog je značaja uređenost imovinskopravnih odnosa, za šta su u pravilu zadužene jedinice lokalne samouprave, bilo kroz stvaranje imovinskog (nekretninskog) portfelja jedinice lokalne samouprave koji će poslužiti za buduću poslovnu zonu, bilo kroz uključivanje u rješavanje određenih, često naslijeđenih imovinskopravnih problema, koji su preduslov za izgradnju, primjera radi, proizvodnih objekata u okviru poslovne zone. U vezi s tim, od presudne je važnosti poznavanje limitirajućih faktora koji su vezani za zakonodavstvo te traženje optimalnih modela za realizaciju poslovnog poduhvata. Na koncu, ali ne manje važno, jest nužnost uvažavanja relevantnih odluka Ustavnog suda Bosne i Hercegovine, koje su u značajnoj mjeri oblikovale de lege lata prizmu u pogledu pravnog statusa značajnog broja nekretnina koje se, pored ostalog, nalaze u obuhvatu sadašnjih, ali i budućih poslovnih zona.

Introduction. Primary rectal signet-ring cell adenocarcinoma represents one of the rarest subtypes (1.39% of cases) and is associated with poor prognosis. Case report. We report the case of a 31-year-old female patient with rectal signet-ring cell adenocarcinoma who developed cutaneous metastases. Conclusion. Despite early initiation of treatment, survival in patients with rectal signet-ring cell adenocarcinoma remains poor. Key words: Rectal Neoplasms, Adenocarcinomas, Signet-Ring Cell, Skin Neoplasms.

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Background: I am approaching this text from one of my articles that was recently published in this same journal, which was “processed” by one of the expert systems. This Artifficial Inteligence (AI) processed article by the system can be an argument that AI can be misused. By comparing the original and the AI copy, the readers can conclude that among those who are challenged by AI, the scientific content can be “converted” from the original into a plagiarized one, thus creating the possibility of endless plagiarism and theft of scientific content that was published in the past in various types of publications, and especially those in world-class journals in the world\'s scientific databases. Objective: The aim of this article was to explain current consequences regarding use AI in science editing of scientific literature. Methods: Author use published articles in most influential indexed databases with topics abot AI which were tolked about influence of AI in preparation articles for publishing in the books, monographs, master and doctor thesis and scientific journals.Results and Discussion: The future of artificial intelligence in education is bright, with the potential to transform the way higher education institutions teach and learn. AI can improve the accuracy and speed of tasks, reducing the risk of human error. Conclusion: The responsible development of AI involves addressing ethical concerns and ensuring accountability and trust. AI systems need to be designed with human oversight and control and it’s essential to address the ethical and practical challenges to ensure that AI benefits all stakeholders in the educational ecosystem, including scientific research and scientific editing..

Economic entities in the global market, within the oil industry, have become aware that they must pay attention to the environment in their business operations. Environmental accounting enables them to track and analyze the necessary information concerning their effects on the environment. For many economic entities, monitoring the harmful impacts on the environment and environmental protection is not only a challenge to meet the requirements of regulatory bodies and supply chains, due to the reputation of business image and consumer pressure, but also due to the necessity of a business strategy that promotes corporate sustainable development. The subject of this research is the analysis of the state of environmental accounting in the oil sector, while respecting the framework of sustainable development faced by economic entities in this sector. The aim of the paper is to investigate how much attention is devoted to environmental accounting and sustainable development in the oil industry in Bosnia and Herzegovina, and to apply the regulations that govern environmental accounting, as well as to systematize the components of environmental accounting, objectives, and dimensions of sustainable development. It has been established that the implementation of environmental accounting is weak, but that in making business decisions, economic entities in the oil sector in Bosnia and Herzegovina rely on the effects of the economic and environmental dimensions of sustainable development.

Akademik Mirko Pejanović u svom višegodišnjem naučnoistraživačkom radu imao je u fokusu nekoliko naučnih polja. On je pratio, izučavao i tumačio politički pluralizam u Bosni i Hercegovini, evropske i euroatlantske integracije u kontekstu Dejtonskog mirovnog sporazuma, državnost BiH u XX i XXI stoljeću, biografije istaknutih ličnosti BiH, nastavno-pedagoški i mentorski rad pojedinih doktoranata na fakultetima širom BiH, a posebno lokalnu i regionalnu samoupravu. Sve naučne oblasti koje su mu bile u fokusu i o kojima je pisao međusobno su povezane i prožimaju jedna drugu, iako na prvi pogled djeluju raznovrsno. Sve ove oblasti čine koherentnu cjelinu unutar političkih i pravnih nauka i, što je veoma važno, fokusirane su na državotvornu dinamiku BiH. Akademik Mirko Pejanović je pristupao ovim temama interdisciplinarno, spajajući politologiju, sociologiju, historiju i pravo, te javnu upravu i regionalizaciju, kako bi dao potpunije i sveobuhvatnije odgovore na ključna pitanja opstanka i razvoja BiH. Posebno mu je značajan naučni i pedagoški rad vezan za lokalnu i regionalnu samoupravu, ostvaren istraživanjima, oblikovanjem i definisanjem ovih veoma važnih oblasti ljudskog života, te doprinoseći razvoju tih oblasti ljudskog djelovanja. Njegov rad je, između ostalog, imao pozitivne posljedice, jer su ideje, istraživanja i pažljiva zaključivanja bili iskazani njegovim brojnim nastupima na konferencijama, okruglim stolovima, predavanjima, kao i napisanim člancima i knjigama, te su imali uticaj i efekte pri donošenju brojnih propisa, ali i u profiliranju politika na državnom i drugim nivoima u BiH.