<p style="text-align: justify;">Bearing in mind that the wheel sleeves of motor vehicles are exposed to strong dynamic loads, and knowing that these are very responsible parts of the constructions, the need for permanent researches of the influence of certain variables on the process of production of them is imposed. The prepared part which, in this case, is obtained by forging from the appropriate steel has an important role. The process of forging, implies the appearance of certain errors that can manifest in many ways. Such mistakes, despite rigorous control, are difficult to eliminate completely. The paper deals with prepared parts with errors and their impact on the consistency of the tools, as well as the analysis of the influence of the change in the percentage of some elements on the same.</p>

<p style="text-align: justify;">The fracture of a part or element of a construction can also be defined as a macroscopic separation of the material that leads to the loss of a solid body load. The fracture is the end result of plastic deformation and occurs when all the potential of the material in terms of elastic and plastic deformation is exhausted. This is the worst case of engineering practices, as it can have great consequences for people and the environment.<br />The study of fractures and their causes began with numerous disastrous failures that caused apart from material damage and loss of human lives. These studies have been going on for years, but despite great knowledge, many of the causes of fractures have not been fully established till now. For this reason, research has led to the development of new methods and new testing procedures in conditions similar to exploitation conditions in order to minimize fracture, especially those sudden and unexpected. In this paper, a brief overview of the types of fractures, fracture testing and possible causes of fractures of metal parts during exploitation will be presented.</p>

The effect of pH and initial concentration on the removal of Cu(II) and Ni(II) ions from their monocomponent and two-component aqueous solutions using Na2CO3 as a chemical precipitation agent was investigated in this paper. Monocomponent aqueous solutions  of Cu(II) and Ni(II)  ions with their initial concentrations of 50 and 500 mg/L and two-component aqueous solution with initial concentration of 500 mg/L were prepared. The precipitation was carried out by batch method at room temperature by stirring the solution at 300 rpm for 5 minutes, resulting in the formation of precipitates. The resulting precipitate was separated by filtration from the solution. The experiment proved that Na2CO3 is a good agent for removing Cu(II) and Ni(II) ions from their monocomponent water solutions of 50 and 500 mg/L concentration and two-component water solution with initial concentration of each metal 500 mg/L. The percentage of Cu(II) removal was higher at lower pH values compared to Ni(II) removal.

<p style="text-align: justify;">The main focus of this paper is to present the TQM practices of 593 companies in Bosnia and Herzegovina. In addition, our results confirm that there are statistically significant differences in TQM practices between firms in a highly competitive and less competitive environment, as well as between firms with and without ISO certificates. TQM practices do not differ between companies that belong to different groups that we constructed based on their age, location, export-orientation and the firm size. We contribute to the existing body of knowledge by identifying organizational contextual factors that might matter in designing more complex structural models.<br /><br /></p>

This chapter examines the concept of digital assets from an angle that has not yet been explored in legal scholarship around digital death and the transmission of digital assets on death. Digital death is conceived herein as the death of an individual who leaves behind various digital fragments of their identity, either in the form of digital assets broadly or as digital biographies, dossiers, autobiographies and archives. Digital death causes uncertainty as to what happens in this dispersed, interconnected and often unregulated digital space, which Kasket lucidly entitles The New Elysium. Most legal scholars have considered digital assets either from a perspective of ‘hard law’ of succession and probate or the intersection of property, contracts and intellectual property; sometimes referring to data protection, jurisdiction or cybercrime. The scholars have not ventured into exploring theory that goes beyond theories of property, intellectual property and privacy. The chapter begins by examining classical conceptualisations of digital assets as property and the ‘”new” new property’, exploring whether this is the correct way to perceive digital assets conceptually. It will then go on to examine post-mortem privacy in the context of digital assets, and introduce a novel link with the Floridian concept of informational bodies. In the attempt to offer a comprehensive framework and a more nuanced normative support for future policy and law, the chapter interrelates all of the concepts with the ideas of postmortal society, introducing a new concept of ‘postmortal privacy’. Finally, the author uses this conceptualisation to test some of the existing legal regimes in the area of the transmission of digital assets. Suggestions from this chapter remain mainly at an abstract level, due to the scope and the nature of the framework it introduces.

Human brucellosis during pregnancy is characterized by significantly less pronounced adverse obstetric outcomes than in animals, but with remarkably more adverse obstetric outcomes when compared to healthy pregnant women. Seroprevalence of brucellosis in pregnancy and cumulative incidence of brucellosis cases per 1000 delivered obstetrical discharges in endemic regions were reported to be 1.5–12.2% and 0.42–3.3, respectively. Depending on the region, the frequency of pregnant women in the cohorts of patients with brucellosis was from 1.5% to 16.9%. The most common and the most dramatic unfavorable outcomes during brucellosis in pregnancy are the obstetric ones, manifested as abortions (2.5–54.5%), intrauterine fetal death (0–20.6%), or preterm deliveries (1.2–28.6%), depending on the stage of pregnancy. Other unfavorable outcomes due to brucellosis are addressed to infant (congenital/neonatal brucellosis, low birth weight, development delay, or even death), the clinical course of disease in mother, and delivery team exposure. When diagnosed in pregnant women, brucellosis should be treated as soon as possible. Early administration of adequate therapy significantly reduces the frequency of adverse outcomes. Rifampicin in combination with trimethoprim-sulfamethoxazole for 6 weeks is the most commonly used and recommended regimen, although monotherapies with each of these two drugs are also widely used while waiting for the results from prospective randomized therapeutic trials. As no effective human vaccine exists, screening of pregnant women and education of all women of childbearing age about brucellosis should be compulsory preventive measures in endemic regions.

The rapid growth in subscribers and usage of multimedia services enlarges the volume of Session Initiation Protocol (SIP) call control signalling creating a need to understand Quality of Experience (QoE) in this case and improve it. This paper provides an analysis of influence of SIP call control signalling on QoE for Voice over Internet Protocol (VoIP) service. The aim was to investigate whether SIP call control signalling load has the influence on the human perception of SIP signalling performances and QoE, and to identify the importance of distinct SIP-based signalling performance metrics. Moreover, the intention was to determine whether SIP call control signalling load changes its impact if previously proposed algorithm for differentiated treatment of SIP messages is activated, and quantify mutual relationships of considered user perceptions and QoE. The findings show that SIP call control signalling load has a strong and negative impact on dependent variables and that the proposed algorithm improves QoE and human perception of SIP signalling performances.

Human activity recognition (HAR) is a classification process that is used for recognizing human motions. A comprehensive review of currently considered approaches in each stage of HAR, as well as the influence of each HAR stage on energy consumption and latency is presented in this paper. It highlights various methods for the optimization of energy consumption and latency in each stage of HAR that has been used in literature and was analyzed in order to provide direction for the implementation of HAR in health and wellbeing applications. This paper analyses if and how each stage of the HAR process affects energy consumption and latency. It shows that data collection and filtering and data segmentation and classification stand out as key stages in achieving a balance between energy consumption and latency. Since latency is only critical for real-time HAR applications, the energy consumption of sensors and devices stands out as a key challenge for HAR implementation in health and wellbeing applications. Most of the approaches in overcoming challenges related to HAR implementation take place in the data collection, filtering and classification stages, while the data segmentation stage needs further exploration. Finally, this paper recommends a balance between energy consumption and latency for HAR in health and wellbeing applications, which takes into account the context and health of the target population.

Abstract 3D - Conformal Radiotherapy (3DCRT) for decades was a standard technique in the prostate cancer radical radiotherapy treatment. Technological advances and implementation of an innovative radiotherapy technique-Intensity Modulated Radiation Therapy (IMRT), enable even more precise treatment of the prostate cancer patients. Intensity Modulated Radiation Therapy (IMRT) is a technological advancement in Conformal Radiotherapy which allows superior conformity and homogeneity of the absorbed dose in planning target volume with maximal sparing organs of risk. This technique gives us possibility to escalate the radiotherapy dose, prerequisite for the adequate local tumor control. Evaluation of dosimetric parameters 3DCRT vs. IMRT: the homogeneity index, the conformity index, parameters of absorbed dose in planning target volume, dose volume constraints for organs of risk shows that IMRT is an optimal technique in the prostate cancer radical treatment.

Excessive phosphorus (P) inputs from agriculture are well established as a contributor to freshwater eutrophication. Decreasing these inputs is an important step in improving the ecological state of impaired waters. Particulate P (PP) is a significant contributor to diffuse P inputs in agricultural catchments. Identifying the main correlates for PP losses is an important step in reducing these inputs. However, there are few studies of long term temporal and spatial dynamics of PP in agricultural streams. Here, we investigate the relative importance of hydrology, catchment characteristics and geochemistry on PP concentrations and fluxes in agricultural headwaters. We evaluate long-term monitoring data from eleven small (<35 km2) Swedish catchments with at least seven years of measured flow and flow proportional water quality sampling. Using parametric and non-parametric regression together with principal components analysis (PCA), we identify in-stream and catchment variables relevant for predicting PP concentrations, e.g., suspended solids concentrations (SS), soil texture and average catchment soil P content, measured as ammonium lactate/acetic acid extractable P (P-AL). We show that PP is primarily correlated to SS concentrations, which in turn are correlated to average clay content and land use. However, the SS:PP relationships differ between catchments. No correlation between PP concentrations in the stream and soil P content was found. An increasing clay content decreases the slope of the relationship between SS and PP, i.e., in catchments with higher clay content, less PP is transported per unit SS. The PP/SS ratio increased significantly (p < 0.05) over time in four catchments, despite limited changes in SS or PP concentrations. Our study highlights the importance of long time series since the enrichment of P on SS in the streams is only detected when using long term monitoring data.

Dishevelled family proteins (DVL1, DVL2, and DVL3) are cytoplasmic mediators involved in canonical and non‐canonical Wnt signaling that are important for embryonic development. Since Wnt signaling promotes cell proliferation and invasion, its increased activation is associated with cancer development as well. To get deeper insight into the behavior of Dishevelled proteins in cancer, we studied their expression in serous ovarian carcinomas [both low‐ (LGSC) and high‐grade (HGSC)], and HGSC cell lines OVCAR5, OVCAR8, and OVSAHO. DVL protein expression in serous ovarian carcinomas tissues was analyzed using immunohistochemistry, while DVL protein and mRNA expressions in HGSC cell lines were analyzed using Western blot and quantitative real‐time PCR. DVL1 protein expression was significantly higher in LGSC compared with normal ovarian tissue, while DVL3 was overexpressed in both LGSC and HGSC. DVL2 and DVL3 protein expression was higher in HGSC cell lines when compared with normal control cell line FNE1, while DVL1, DVL2, and DVL3 mRNA expression was significantly increased only in OVSAHO cell line. Survival analysis revealed no significant impact of DVL proteins on patients’ outcome. Our data show an active involvement of Dishevelled family proteins in serous ovarian carcinomas. Further studies should confirm the clinical relevance of these observations.