The last decade was marked by rapid growth and development of technology. One example of that is the automotive industry. This industry has made an enormous progress, and its main goal is to achieve safer and better driving. The vehicle incorporates GPS devices that send information about the current location and speed of the vehicle. Large amounts of collected data can be used in companies for tracking vehicles and various analysis and statistics. Sometimes, however, GPS data is not accurate. In this paper, the potential of real data sets will be used to analyze possible anomalies that may occur when reading GPS position of vehicles. The approach for solving this problem used in this paper consists of calculating distance and time, based on GPS measurements, then calculating average speed based on these two values, and comparing that speed with the speed given by GPS device.

Paper illustrates the process of topic modeling and text classification. Specifically, the dataset used is a corpus consisting of scientific publications published by Neural Information Systems Processing Conference. Topic modeling itself is performed using Latent Dirichlet Allocation model. It is followed by optimization of a number of topics on the basis of topic coherence, a quality measure of human interpretability. Results of topic modeling are used for labeling data prior to text classification. Labels are determined based on the distribution of assigned papers' topics over time. Specifically, peak changes used for differentiating between time periods dominated by specific topics are calculated as a Kullback-Leibler divergence. Finally, transforming data into the feature vectors, several different text classification approaches are evaluated. As observed, the greatest accuracy score is recorded for the use of extreme gradient boosting classifier being 77.1%.

Current guidelines do not recommend thrombolytic therapy for the treatment of intermediate-risk pulmonary embolism (PE) because of the tight balance between the benefit and safety with classic protocols. The aim of this study was to compare the new thrombolytic protocol with lower-dose slow-infusion (LDSI) of tissue plasminogen activator (tPA) to classic 2-hours tPA infusion protocol or no-reperfusion in patients with intermediate-high risk PE with higher bleeding risk regarding 30-day efficacy and safety. Among 849 patients with PE from the Serbian multicenter registry, 469 patients who fulfilled criteria for intermediate-risk PE were involved in the study. After propensity score matching 425 patients [263 (61.9%), 99 (23.3%) and 63 (14.8%) were treated with no-reperfusion, classic tPA protocol (100 mg for 2 hours) and LDSI of tPA (2–5 mg/hour either vie local catheter or systemic venous infusion with dose range of 25–50 mg)]. The basic characteristics of patients were well balanced between groups except that patients treated with LDSI of tPA had significantly higher usage of drugs which can be associated to bleeding and more previous bleeding events. Thirty day all-cause and PE-caused mortality and 7-day major bleeding were the main efficacy and safety end-points, respectively. All-cause and PE-cause 30-day mortality were 8.7% vs 16.2% vs 1.6% (Log rank p=0.007) and 4.5% vs 11.0% vs 0.0% (Log rank p=0.008) in patients with no-reperfusion, classic tPA protocol and LDSI of tPA protocol, respectively. Major bleeding at 7 days were 2.7% vs 8.1% vs 14.3% (Log rank p=0.001) in patients with no-reperfusion, classic tPA protocol and LDSI of tPA protocol, respectively. There was one fatal intracranial bleeding during catheter infusion of tPA. Lower-dose slow-infusion of tPA protocol decreased significantly all-cause and PE-cause mortality at 30-day at the cost of excess of non-fatal major bleeding at 7-day in patients with intermediate-risk PE and higher risk for bleeding. None

Coronary collateral circulation exerts protective effects on myocardial ischemia due to coronary artery disease (CAD) and can be promoted by exercise (E) with heparin (H) co-administration. Whether this arteriogenetic effects is accompanied by functional improvement of left ventricle (LV) during stress remains unknown. To establish the stress-induced functional effects on LV regional and global function of 2-week cycle of H+E in patients with “no-option” CAD. In a prospective, single-center, double-blind, randomized, parallel-group study we recruited 32 “no-option” patients (27 males; mean age of 61±8 years), with stable angina and CTO, refractory to OMT, not suitable for revascularization and with E-induced ischemia. All underwent 2-week cycle of E (2 E test per day, 5 days a week) and were pre-treated with i.v. 0.9% saline or unfractionated H (100 IU/kg up to maximum of 5.000IU, 10 min prior to E). Canadian Class Score (CCS) and 12-lead E-ECG for time-to-1 mm ST-segment depression were assessed at entry and after treatment. LV function was evaluated during treadmill exercise with conventional and advanced imaging indices: Wall Motion Score Index (WMSI); Ejection Fraction (EF); Force (systolic blood pressure/end-systolic volume); Global Longitudinal Strain (GLS). Post-treatment exercise-time and CCS improved in both groups. In H+E patients exercise-time improved from 369.8±107.8 sec to 475.3±114.6 sec (p=0.001) while in E patients improved from 384±152.7 sec to 464.8±134.1 sec (p=0.019). CCS score changed in H+E from 2.6±0.7 to 1.9±0.7 (p=0.000), and in E group from 2.4±0.7 to 2.1±0.9 (p=0.046). At peak exercise, H+E was different from E group for EF and GLS (see Table). Effects of H+E on SE parameters H+E p P+E p *H+E vs P+E STRESS Time 0 vs Time 1 Time 0 vs Time 1 Time 0 Time 1 WMSI 1.377 vs 1.279 0.005 1.404 vs 1.376 0.290 0.626 0.255 EF (%) 60.9 vs 64.8 0.016 61.2 vs 57.8 0.284 0.943 0.016 Force (mmHg/mL) 6.36 vs 6.5 0.158 5.82 vs 4.68 0.209 0.760 0.098 GLS (%) −16.96 vs −18.50 0.001 −15.79 vs −15.60 0.380 0.325 0.027 SE = stress echocardiography; H+E = heparin+exercise; P+E = placebo+exercise; Time 0 = before randomization; Time 1 = after 2-week therapy cycle. *p values. A 2-week, H+E cycle is associated with improvement in regional and global LV function during exercise, concordantly shown by conventional (WMSI, EF) and advanced (GLS) echocardiographic indices of LV function. This integrates and supplements the classical objective index based on ST-segment depression, unable to localize and quantify the functional consequences of therapy on myocardial ischemia.

Heart failure is a major cause of morbidity, mortality and re-hospitalizations and is highly prevalent in myocardial infarction survivors. Cardiac rehabilitation based on exercise training and heart failure self-care counseling have each been shown to improve clinical status and clinical outcomes. We designed our study with aim to evaluate the usefulness of exercise based in house cardiac rehabilitation/ secondary prevention program in patients with heart failure with mid-range ejection fraction (HFmrEF) after myocardial infarction. Out of 2753 patients who were admitted to our three weeks in- hospital secondary prevention program – exercised based cardiac rehabilitation, we analyze a total of 219 patients who were admitted early after coronary revascularization (percutaneus coronary interventions or coronary bypass surgery) with HFmrEF. The majority of patients were males (68%). Risk factors and co morbidities were noted. Patients were selected for exercise training after six minute walking test or exercise stress test (cardiopulmonary dominantly to evaluate unexpected exertional dyspnea). After 3 weeks in house cardiac rehabilitation the patients were re-tested. The major comorbidities in our patient population were as follows: hypertension, diabetes and dyslipidemia. Six minutes walking test was performed and the total distance walked ranged from 120 to 480 meters and the beginning of the program. Patient had 7 -days a week training program. After the 3 weeks in hospital exercise rehabilitation the improvement in the test was ∼32%. Cardiopulmonary test showed also improvement of functional capacity.We noted several rhythm disturbance complications by telemetry (VES, SVES). None had acutisation of heart failure (with peripheral edema and congestion). All patients fulfilled cardiac rehabilitation program. Supervised multidisciplinary cardiac rehabilitation program, including an individualized exercise component is effective and can improve functional status and exercise tolerance in patient with HFmrEF after myocardial infarction.

Receiver functions are sensitive to sharp seismic velocity variations with depth and are commonly used to constrain crustal thickness. The H–κ stacking method of Zhu & Kanamori is often used to constrain both the crustal thickness (H) and ${V_P}$/${V_S}$ ratio ($\kappa $) beneath a seismic station using P-to-s converted waves (Ps). However, traditional H–κ stacks require an assumption of average crustal velocity (usually ${V_P}$). Additionally, large amplitude reverberations from low velocity shallow layers, such as sedimentary basins, can overprint sought-after crustal signals, rendering traditional H–$\ \kappa $ stacking uninterpretable. We overcome these difficulties in two ways. When S-wave reverberations from sediment are present, they are removed by applying a resonance removal filter allowing crustal signals to be clarified and interpreted. We also combine complementary Ps receiver functions, Sp receiver functions, and the post-critical P-wave reflection from the Moho (SPmp) to remove the dependence on an assumed average crustal ${V_P}$. By correcting for sediment and combining multiple data sets, the crustal thickness, average crustal P-wave velocity and crustal ${V_P}$/${V_S}$ ratio is constrained in geological regions where traditional H–$\ \kappa $ stacking fails, without making an initial P-wave velocity assumption or suffering from contamination by sedimentary reverberations.

OBJECTIVES Urinary tract infections (UTIs) are common problems in women, and important reason for visiting primary care physicians, resulting in substantial financial burden to community. The aim of this study was to determine the resistance rates of E. coli to commonly prescribed antimicrobial drugs for community-acquired UTIs in women and to establish the association between age and resistance to antibiotics among isolates of E. coli from urine. METHODS The study was designed as a retrospective cross-sectional study during the 5-years period. It was conducted on a sample of urinary tract isolates of E. coli taken from women with community-acquired UTIs. After prevalence of E. coli resistance to antibiotics was established, the analysis of risk factors for emergence of resistance was conducted. RESULTS There were 10,734 isolates of E. coli, comprising 70.62% of all samples analyzed. E. coli was the most frequently resistant to ampicillin (54.68%), followed by trimethoprim-sulphamethoxazole (37.46%), first and second generation cephalosporins (cephalexin and cefaclor) (29.53% both), and ciprofloxacin (23.80%). Less than 50% of E. coli isolates was sensitive to all three tested antibiotics, and nearly 13% acquired triple-resistance. Prevalence of isolates resistant to two or three agents was higher in the subgroup of women older than 65 years. CONCLUSIONS Empirical choice of antimicrobial agent for community-acquired non-complicated UTIs in women should be individualized on the basis of the patient's age, prevalence of resistance in the local community, and compliance history of the patient.

The agricultural sector is a source of greenhouse gas emissions that directly affect the global problem of climate change and contribute approximately 11% in total greenhouse gas emissions in the world and in Croatia too. Irregular and irresponsible agricultural practices, such as excessive tillage and improper fertilization often lead to soil carbon loss and increased carbon dioxide emissions to the atmosphere. This field study provides results how agricultural practices affect carbon dioxide emissions from soil, carbon sequestration and soil quality during the cultivation of winter wheat. The field experiment was conducted in a temperate continental climate on distric Stagnosol. Four investigated treatments were: organic fertilization, mineral fertilization, control treatment and black fallow. The lowest carbon dioxide emission was recorded on bare soil and the highest on organic fertilization treatment. The application of manure, mineral fertilizers and calcification rendered significant effect on some soil chemical characteristics and daily carbon dioxide flux.

In recent times, the global financial system has embraced more people from more regions of the world, but we are yet to fully understand who remains excluded and why. Globally, 2 billion adults are still unbanked (World Bank, 2015). Of those, many are poor women. Even when they gain financial access, women tend to refrain from actively using their bank accounts. India represents a potent example of this global challenge. Our study offers a quantitative analysis of the Financial Insights Inclusion and Findex datasets and finds that even when they are given the opportunity and potential benefits of financial access - many of India’s poor women opt out of actively engaging with the formal banking institutions. In examining reasons behind their account dormancy, we find that education is a significant determinant shaping decisions of India’s poor women.

Purpose: Thanks to the positive health effects of physical exercise, physical education is an integral part of the education system, with two hours per week, which is insufficient to achieve an optimal effect in transforming the anthropological status of children. The aim of the research was to determine the effects of regular and modified physical education with the application of contents from sports games (basketball, volleyball and handball) in the duration of one semester to changes in basic motor skills in pupils of the fifth grade of elementary school. Material: The study included N = 106 students of the V class, aged 10 to 11 years, clinically and mentally healthy, and with no pronounced morphological and locomotor impairments. The sample of examinees was divided into two subgroups. The first was an experimental group of 53 students, who carried out physical education classes according to the modified plan and program of sports games (basketball, volleyball and handball) for a semester. The other was a control group of 53 students who attended regular classes from physical education according to the current curriculum. Results: The results of the research at the descriptive level showed noticeable differences between the same groups in the final versus the initial measurements. Based on the results of the t-test for the control and experimental group, it can be concluded that there have been statistically significant changes in values on all variables of basic motor in the final compared to the initial measurement. By analyzing the results of the t-tests, it can be seen that the groups differ in the initial measurement only in one basic motor variable, MTAPN, and this difference is statistically significant in favor of the control group. In the final measurement, there are no significant differences between the control and the experimental group in the average values of all variables of basic motoring. Conclusions: Improving basic motor skills depends on the teacher's ability, the ability to transform the age with which he is working, and the success of certain training processes. The modified program of the experimental group has led to changes and thus proves the significant effect of the group's work program.

The analysis of meteorological data from the period 1961–2014 show the rise in the mean annual temperature in the entire territory of Bosnia and Herzegovina. The changes are more pronounced in the central – hilly part of the country. The increase in annual air temperature ranges from 0.4 to 1.0°C per decade, whereas temperature increases during vegetation period were up to 1.2°C per decade. Additionally, increases in air temperature over the last fourteen years are even more pronounced. Changed distribution of precipitation, significant variations and the increasing soil moisture deficit during vegetation period (April – September) are also evident in Bosnia and Herzegovina. The increase in air temperature combined with changes in the distribution of precipitation has resulted in a change of evapotranspiration and annual water balance. The main objective of this study was to determine and compare the severity of changes in mean annual water balance components between different regions in Bosnia and Herzegovina. Monthly weather data from 26 weather stations in Bosnia and Herzegovina, for the time period of 50 years (1967 – 2016) were used to determine and analyze impact of climate change on the following water balance components: temperature, precipitation, reference evapotranspiration, actual evapotranspiration, total runoff, soil moisture deficit and amount of snow. The results indicate that climate change has a substantial effect on the all water balance components. Air temperature (0.21 - 0.7 o C per decade), reference evapotranspiration (0.61 - 42.81 mm per decade) and soil moisture deficit (1.35 - 27.71 mm per decade) show an increasing trend over the entire territory of Bosnia and Herzegovina with the strongest increase in the north-west part of the country.

Universiteler sadece egitim merkezleri degil ayni zamanda bilgi uretimi, inovasyon ve teknik gelisim merkezleridir. Bununla birlikte son yillarda universiteler, yerel ekonomiler icin kilit bolgesel ekonomik kalkinma merkezlerinden biri olarak kabul edilmektedir. Universiteler, kampusun yakinindaki cografi bolgelere cesitli bicimlerde ekonomik aktivitelerle buyuk katki saglamaktadir. Literaturde universitelerin bolgesel ekonomik etkisini arastiran bircok calisma bulunmaktadir. Bu calisma, Uluslararasi Saraybosna Universitesi (IUS)'nden, ogrencilerinden ve calisanlarindan ve ziyaretcilerinden elde edilen bilgileri ve verileri kullanarak Bosna Hersek'te bu alanda yapilan yapilan ilk calismadir. Bu calisma, IUS'in yerel harcama ve istihdam uzerindeki dogrudan ekonomik etkisini ve IUS'un Saraybosna ekonomisi uzerindeki dolayli neden oldugu ekonomik etkilerini bulmayi amaclamaktadir. Calisma, IUS'nin Ilidza ve Saraybosna ekonomisine dogrudan ekonomik faydalar seklinde yaklasik 10 milyon KM, dolayli faydalarda 24 milyon KM ve 41 milyon KM uyarilmis katkisi oldugunu ortaya koyuyor. Bu katkilarin toplami yilda 75 milyon KM'ye ulasmaktadir. Ayrica IUS, Ilidza ve Saraybosna bolgesinde 231 dogrudan ve dolayli olarak 1.065 istihdam (toplamda 1.296 kisi) yaratmaktadir.