Background: It is clear that in developed countries more women die annually from ovarian cancer than from all other gynecologic malignancies combined. Objective: The aim of this article is to analyze current possibilities and propose adequate measures which can help the development of effective screening methods/assays for the early detection of epithelial ovarian cancer. Results and Discussion: This article updates the status of ovarian cancer screening and addresses most relevant studies published during the last five years. The developments that followed the review are best summarized in reference to the screening tests, target populations and newly published trials. The possible role of 3D ultrasound technology, especially 3D power Doppler imaging, in early and accurate detection of ovarian malignancy is discussed. We described our new ovarian cancer screening trial, which started in January 2001. Improvements in ultrasound technology such as 3D volume acquisition and 3D power Doppler imaging may have clinical utility in a more reliable identification of an abnormal ovarian vascularity and architecture. 3D volume acquisition allows for careful evaluation of the internal surfaces of cyst walls for excrescences otherwise not appreciated by 2D ultrasound. Conclusion: While the addition of 3D power Doppler provides a new tool for measuring the quality of ovarian tumor angiogenesis, improving accurate diagnosis of ovarian malignancies, its clinical value for the early detection of ovarian carcinoma has yet to be determined.

Assessment of historical buildings presents specific engineering task, considering the ways they were built and the materials, which were used. Many of them belong to cultural heritage and merit special care and protection. This concerns also the historical buildings in Bosnia and Herzegovina. The country is situated in seismic active region of South-East Europe and the majority of the historical buildings were made of stone-masonry. In the case of stronger earthquake motion such buildings could suffer heavy damages. The damages are sometimes cumulated through many years and many causes. Substantial damages were caused by recent war disaster, as well. The aim is to preserve and reveal their aesthetic and historical values and to use original materials and original way of construction, if possible. In most cases seismic assessment procedures result in the requirements for the strengthening or retrofit of the old masonry building structures. Design and construction procedures of repair and strengthening of two medieval stone masonry buildings are presented. Equilibrium between aesthetical and structural demands is discussed.

Introduction/Objective. Malocclusions are one of the most frequent disorders in dentistry, and pose a risk for the onset of caries and periodontal diseases. Fixed orthodontic treatment solves the problem of malocclusions; however, it requires simultaneous cooperation of the patients, parents, and dentists involved. The objective of this study is to examine the effects of fixed orthodontic therapy on the Streptococcus mutans and Lactobacillus spp. bacteria in saliva, the pH value, and buffering capacity of saliva. Methods. The research was carried out at the Faculty of Medicine in Foca, Department of Dentistry. The study included 100 respondents, aged 13 to 17 years. The respondents were divided into two groups: the study group (respondents wearing fixed braces) and the control group (respondents not subjected to fixed braces therapy). Saliva samples were taken from the respondents four, 12, and 18 weeks after the start of the orthodontic therapy. The study used the bacteria caries risk test (CRT) and CRT buffer (Ivoclar Vivadent). Results. The study showed an increased number of bacteria in saliva of the respondents during all three follow-up periods (χ2 test, p = 0.001). The largest numbers of the Streptococcus mutans and Lactobacillus spp. bacteria were found in week 12 of the therapy. Saliva pH value and buffering capacity of saliva increased statistically significantly in week 12 of the therapy (χ2 test, p = 0.001). Conclusion. Oral conditions in patients changed during the fixed orthodontic therapy: the number of bacteria increased, the pH value and buffering capacity of saliva changed. It was necessary to use preventive measures in order to avoid complications during the fixed orthodontic appliances therapy.

Purpose: Change of direction speed (CODS) and reactive agility (RAG) are important qualities in futsal, but studies rarely examined the predictors of these conditioning capacities in players of advanced level. This study aimed to evaluate predictive validity of certain anthropometric and conditioning capacities in evaluation of futsal specific CODS and RAG in top-level players. Methods: The sample comprised 54 male players from Croatia and Bosnia and Herzegovina, members of teams competing at the highest national rank, including national champions for the 2017–2018 competitive season in both countries. The variables comprised set of predictors (body mass, body height, triceps skinfold, reactive strength index [RSI], sprint 10 m [S10M], and broad jump [BJ]; and four criteria: futsal specific CODS and RAG, performed with and without dribbling (CODS_D, CODS_WD, RAG_D, RAG_WD). To identify the association between variables Pearson’s correlation and multiple regressions were calculated. Results: Observed predictors explained statistically significant (p < 0.05) percentage of variance for all four criteria (Rsq: 0.28, 0.30, 0.23 and 0.25, for CODS_WD, CODS_D, RAG_WD, RAG_D, respectively). Body mass was significant predictor for all criteria (Beta: 0.35–0.51), with poorer performances in heavier players. In both performances which involved dribbling, significant predictors was RSI (Beta: −0.27 and −0.31 for CODS_D and RAG_D, respectively), with superior performances in players with better RSI. The S10M and BJ were not identified as being significantly correlated to studied RAG and CODS performances. Conclusion: Study confirmed specific influence of studied predictors of futsal specific CODS and RAG with consistent negative influence of body mass on studied performances. Almost certainly this can be explained by specifics of RAG and CODS execution. Specifically, tests are performed over relatively small distances, with several changes of direction, which clearly mimic the futsal specific performances. Although sprint performance is often observed as important determinant of CODS and RAG, herein we did not confirm its predictive validity in explanation of futsal specific CODS and RAG. Future studies should evaluate other potentially important predictors of these capacities in futsal.

Jedno je od glavnih istraživačkih područja u socijalnoj kogniciji životinja kooperativno rješavanje problema, tj. kognicija kod međusobne suradnje životinja. Smatra se da je socijalna kognicija evoluirala zbog zahtjeva koje donosi život u grupama i često se drži adaptacijom za takav život. Analiza socijalnoga učenja, drugoga istraživačkog područja unutar socijalne kognicije, pokazala je da je ta pretpostavka u literaturi prouzročila dva problema. Prvo, postoji pristranost prema testiranju socijalnih vrsta, i drugo, postoji a priori pretpostavka da je socijalno učenje kvalitativno drugačije od individualnoga. Ta dva problema nisu nužno ograničena na socijalno učenje, nego mogu biti prisutna i u drugim poljima unutar istraživanja socijalne kognicije. Primjena slične analize na kooperativno rješavanje problema ukazuje da i u tome području postoje oba problema. Prvo, empirijska se istraživanja provode ponajprije na vrstama koje su socijalne i na onima koje pokazuju kooperativna ponašanja u divljini. Drugo, pretpostavka da se kooperativno rješavanje problema temelji na specifično socijalnim kognitivnim sposobnostima implicirana je u velikome dijelu literature. Moguće je da je to rezultat miješanja različitih komponenti unutar kognitivnoga procesa: koja je informacija potrebna za uspješnu kooperaciju i kako se ta informacija stječe. Dok prva komponenta mora uključivati informaciju o drugome pojedincu, ne postoji indikacija da se druga komponenta mora razlikovati od već poznatih, općenamjenskih mehanizama. Ta dva problema sprečavaju sistematsko ispitivanje razlika između vrsta i ometaju istraživanje evolucije kooperativnoga rješavanja problema.

Introduction. The success of endodontic treatment depends on the adequate biomechanical preparation and obturation of the entire root canal system. The untreated or poorly debrided/obturated root canals are among the most frequent causes of endodontic treatment failure. The endodontic treatment of maxillary molar has the highest failure rates due to the complexity of their root canal anatomy. The aim of the study is to present the endodontic treatment of maxillary second molar with two roots and two canals. Case report. The clinical case report presents the endodontic treatment of maxillary second molar with two roots and two canals in a patient, aged 32 years. After the analysis of preoperative diagnostic radiograph, opening the pulp chamber and access cavity preparation, two canal orifices were localized. After the biomechanical preparation, root canals were obturated with the Gutta-percha points and sealer during the same visit. Conclusion. Although maxillary second molar most commonly varies in terms of the number of root canals in the buccal roots, less common variations in anatomical and morphological traits, such as the presence of two roots and two canals, should be considered during endodontic treatment.