12th Days of the Academy of Medical Sciences of Bosnia and Herzegovina (AMNuBiH) this year were organized together with the International Academy of Sciences and Arts in Bosnia and Herzegovina in Sarajevo on December 4, 2021. The title of the symposium was “Scientometry, Citation, Plagiarism and Predatory in Scientific Publishing”. Experiences in the scientific area covered by title of this conference were presented by some of the most influential scientists from Bosnia and Herzegovina, who are included between 2% of authors in the Stanford scientometric list, which was published in October 2021 in the journal Biology Plos. Some of the authors are former or current Editors-in-Chiefs of indexed biomedical journals in Bosnia and Herzegovina, Croatia, North Macedonia (Izet Masic, Asim Kurjak, Doncho Donev, Osman Sinanovic). Also, Sylwia Ufnalska and Izet Masic are or were members of the European Association of Science Editors (EASE) and they have great experiences about the topic of this conference. Science that analyzes scientific papers and their citation in the scientific journals – called scientometrics – day by day has become important for measuring scientific validity and quality of all kinds of publications deposited in the most important on-line scientific databases, like WoS, Scopus, Medline, PubMed Central, Embase, Hinari, etc., but also in academic platforms ResearchGate and Academia.edu. Scientometrics use the Impact and Echo factor for measuring the quality of publications in WoS journals, Scopus uses the h-Index, and the most common one used in the last 10 years is Google Scholar index. All of them have advantages and disadvantages, and also positive and negative influences in the academic praxis. One of the greatest, and sadly too common, problems which participants in the academic process encountered are plagiarism and predatory publishing. In order to prevent this severest form of academic fraud, authors must give credit to someone whose work has helped him/her by citing references correctly. This presentations of the symposium "SWEP 2021") analyzed the major components of scientometrics, the basic mechanisms of citations in medical publications and plagiarism, as an opposition to the primary goal of scientific enterprise: search for truth.

Abstract The adrenal abscess is a rare complication of adrenal hemorrhage in the neonatal period. Due to its rare occurrence and non-specific signs, diagnosing and treating an adrenal abscess in the neonatal period might be challenging. We present herein a 3-week-old male neonate with an adrenal abscess associated with Escherichia coli sepsis, which was successfully treated by open surgery (using the minimal posterior lumbar approach) following an unsuccessful ultrasound-guided percutaneous drainage.

Background: The pandemic of COVID-19 has affected all spheres of life, including education. Teachers at all levels were faced with numerous challenges during the pandemic. These challenges had an impact on their mental health. Objective: The goal of the present study was to examine the depression, anxiety, and stress levels in teachers in Bosnia and Herzegovina. Methods: The sample for this study consisted of 559 teachers (471 female teachers and 88 male teachers). We used the Depression, Anxiety, and Stress Scale (DASS 21) to measure teachers’ emotional states of depression, anxiety, and stress. Results: The findings of this study clearly indicate the high levels of depression, anxiety, and stress in teachers. We also identified that levels of support provided by family members and school administration served as protective factors in the time of crisis. Conclusion: Teachers in Bosnia and Herzegovina have a high prevalence of elevated depression, anxiety, and stress levels. The article concludes with some recommendations on how to improve the mental health of teachers.

Background Over a third of critical illness survivors suffer from mental health problems following hospitalization. Memories of delusional experiences are a major risk factor. In this project, ICU doulas delivered a unique positive suggestion intervention targeting the vulnerable time period during critical illness when these memories are formed. Methods Adult critically ill patients were recruited for this single-arm, prospective pilot study. These ICU patients received a positive suggestion intervention daily during their ICU stay in parallel with their medical treatment. The intervention was designed to be delivered over a minimum of two sessions. Feasibility was defined as intervention delivery on ≥ 70% of ICU days after patient enrollment. As a secondary analysis, psychometric questionnaires were compared to those of a historic control cohort of patients receiving standard care in the ICU using adjusted linear regression models. Results Of the 97 patients who received the intervention and were alive at the end of their ICU course, 54 were excluded from analyses mostly for having received only one session because of a short ICU length of stay of < 2 days, transitioning to comfort care or not wanting to answer the study questionnaires. Forty-three patients who completed 2 or more sessions of the positive therapeutic suggestion intervention provided by two trained ICU doulas received it for a median of 4 days (IQR 3, 5), with each session lasting for a median of 20 min (IQR 14, 25). The intervention was delivered on 71% of days, meeting our pre-determined feasibility goal. Compared to historical controls ( N  = 299), patients receiving the intervention had higher severity of illness and longer length of stay. When adjusted for baseline differences, patients both with and without mechanical ventilation who received the intervention scored lower on the Hospital Anxiety and Depression Scale (HADS)—Depression subscale. The intervention was also associated with reduced HADS-Anxiety subscale among ventilated patients. Conclusions Positive therapeutic suggestion delivered by ICU doulas is feasible in the ICU setting. A randomized trial is warranted to better delineate the role that positive suggestion and ICU doulas may play in ongoing interprofessional efforts to humanize critical care medicine. The study was registered on clinicaltrials.gov (NCT03736954) on 03/14/2018 prior to the first patient enrollment https://clinicaltrials.gov/ct2/show/NCT03736954?cond=ICU+Doulas+Providing+Psychological+Support&draw=2&rank=1 .

Background: Breast cancer in women is the second most common and accounts for approximately 18% of all malignant tumors in women worldwide. The etiology of breast cancer is not clear enough. Starting from the assumption that the manifestation of breast cancer may have a multifactorial model, this article compares the population-genetic structure of patients (experimental group) with the population-genetic structure of healthy population (control group). Objective: The aim of the study was to examine the possible genetic basis of the Rh factor relationship with selected homozygous-recessive traits of females with breast cancer, and to diagnose the probability (assess the risk) of developing the disease in healthy women by analyzing homozygous-recessive traits (HRT). Methods: This are an anthroposcopic-qualitative study that included two groups of subjects, experimental and control (a total of 80 subjects). An analysis of the percentages within each group was performed using the Chi-square test. The results are presented in tables, and the accepted level of significance is at the level of p <0.05. Results: In the group of Rh+ subjects, the correlation of this type of Rh factor with the breast cancer was proven, given the frequency of the phenotype of homozygous-recessive traits in them. A statistically significant difference was found for 4 traits, and three are also close to the set significance level. In subjects with Rh- factor, a statistically significant difference was found for only one trait (absence of mallets on the phalanges). Conclusion: Although the number of subjects was relatively small, we can conclude that in the experimental group a higher frequency of recessive phenotypes for the examined traits was recorded, which indicates the genetic load of the subjects from this group. Correlation with Rh factor was observed in the case of subjects of the experimental group with Rh+ factor.

Cotoneaster integerrimus represents a multiploid and facultative apomictic system of widely distributed mountain populations. We used flow cytometry to determine genome size, ploidy level, and reproduction mode variation of the Balkan populations, supplemented by analysis of nuclear microsatellites in order to address: (i) geographic distribution and variation of cytotypes among the populations; (ii) variation of reproduction mode and the frequency of sexuality; (iii) pathways of endosperm formation among the sampled polyploids and their endosperm balance requirements; (iv) genotypic diversity and geographic distribution of clonal lineages of polyploids. The prevalence of apomictic tetraploid cytotype followed by sexual diploids and extremely rare triploids was demonstrated. This prevalence of tetraploids affected the populations’ structure composed from clonal genotypes with varying proportions. The co-occurrence of diploids and tetraploids generated higher cytotype, reproductive mode, and genotypic diversity, but mixed-ploidy sites were extremely rare. The endosperm imbalance facilitates the development and the occurrence of intermediate triploids in mixed-ploidy populations, but also different tetraploid lineages elsewhere with unbalanced endosperm. All these results showed that the South European populations of C. integerrimus have higher levels of cytotype and reproductive diversity compared to the Central European ones. Therefore, the South European populations can be considered as a potential reservoir of regional and global diversity for this species.

OBJECTIVES To test the influence of a bleaching procedure using 16% carbamide peroxide (CP) on the colour of composite materials and their consecutive subjection to discolouration in beverages. MATERIALS AND METHODS Nanocomposite Z550 (3M ESPE) and the microhybrid Z250 (3M ESPE) composite materials were selected for the research. 16% CP was applied to composite plates (15 samples each material) for seven hours a day for 14 days simulating at-home nightguard vital bleaching. The test samples were then divided randomly into three sub-groups and submerged in instant coffee, green tea and Coca Cola for 30 days. The control group (N=5) samples were kept in deionized water. Determination of the L*a*b* dimensions of colour of the polymerized discs was performed by calibrated spectrophotometer 24 hours later, after the bleaching procedure, and on days 7, 15 and 30 after immersion in the beverages. RESULTS After application of 16% CP, there were perceptible changes in the colour of both test materials, which did not exceed the boundaries of acceptability (ΔE<3.48). Coca-Cola did not cause discolouration of the tested composites, but coffee and tea changed their colour above the level of perceptibility already seven days after immersion. A statistically significant difference in the change in colour was established between the materials when they were immersed in coffee (P<0.05). CONCLUSIONS 16% CP does not affect the basic colour of the composites. Immersion in a beverage led to an unacceptable change in the colour of both test materials in coffee and tea, primarily towards black. The greatest discolouration after bleaching was shown by Z550 when immersed in coffee.

Healthy and controlled immune response in COVID-19 is crucial for mild forms of the disease. Although CD8+ T cells play important role in this response, there is still a lack of studies showing the gene expression profiles in those cells at the beginning of the disease as potential predictors of more severe forms after the first week. We investigated a proportion of different subpopulations of CD8+ T cells and their gene expression patterns for cytotoxic proteins (perforin-1 (PRF1), granulysin (GNLY), granzyme B (GZMB), granzyme A (GZMA), granzyme K (GZMK)), cytokine interferon-γ (IFN-γ), and apoptotic protein Fas ligand (FASL) in CD8+ T cells from peripheral blood in first weeks of SARS-CoV-2 infection. Sixteen COVID-19 patients and nine healthy controls were included. The absolute counts of total lymphocytes (p = 0.007), CD3+ (p = 0.05), and CD8+ T cells (p = 0.01) in COVID-19 patients were significantly decreased compared to healthy controls. In COVID-19 patients in CD8+ T cell compartment, we observed lower frequency effector memory 1 (EM1) (p = 0.06) and effector memory 4 (EM4) (p < 0.001) CD8+ T cells. Higher mRNA expression of PRF1 (p = 0.05) and lower mRNA expression of FASL (p = 0.05) at the fifth day of the disease were found in COVID-19 patients compared to healthy controls. mRNA expression of PRF1 (p < 0.001) and IFN-γ (p < 0.001) was significantly downregulated in the first week of disease in COVID-19 patients who progressed to moderate and severe forms after the first week, compared to patients with mild symptoms during the entire disease course. GZMK (p < 0.01) and FASL (p < 0.01) mRNA expression was downregulated in all COVID-19 patients compared to healthy controls. Our results can lead to a better understanding of the inappropriate immune response of CD8+ T cells in SARS-CoV2 with the faster progression of the disease.

Abstract The main aim of this paper is to explore the factors determining Microfinance institutions (MFIs) self-sufficiency. The data on selected variables for this research were obtained from the public MIX Market Database and cover the year of 2017. The empirical model is constructed with application of a Principal Component Analysis (PCA) and Logistic regression analysis. Sample is consisted of 342 MFIs from all around the world, with 21 independent variables grouped into eight factors/components, and OSS (operational self-sufficiency) as dependent variable. The obtained results suggest that higher revenue and MFIs profitability combined with decrease of credit risk lead to higher probability of MFI to be self-sufficient. These results also confirm widespread belief that MFIs will not be able to achieve their social goals without achieving sustainable profitability. In addition, results also confirm importance of MFIs core mission as with increase in outreach, probability of MFIs achieving self-sustainability also increases.

Abstract This paper explores the role of knowledge visualization in facilitating decision-making in cultural heritage management. The paper addresses the issue in the specific context of stećci - the tombstones from medieval Bosnia inscribed on the UNESCO world heritage list. Grounded in the distant reading paradigm, the paper introduces a series of visualizations of spatial, temporal, architectural, iconographical, epigraphical, and impact analyses of stećci data. Together, these visualizations should enable decision-makers to gain an enhanced understanding and knowledge of this important cultural heritage. In turn, this should help them make better decisions regarding their protection and promotion.

Columnar microstructures are critical for obtaining good resistance switching properties in SiO x resistive random access memory (ReRAM) devices. In this work, the formation and structure of columnar boundaries are studied in sputtered SiO x layers. Using TEM measurements, we analyze SiO x layers in Me–SiO x –Mo heterostructures, where Me = Ti or Au/Ti. We show that the SiO x layers are templated by the Mo surface roughness, leading to the formation of columnar boundaries protruding from troughs at the SiO x /Mo interface. Electron energy-loss spectroscopy measurements show that these boundaries are best characterized as voids, which in turn facilitate Ti, Mo, and Au incorporation from the electrodes into SiO x . Density functional theory calculations of a simple model of the SiO 2 grain boundary and column boundary show that O interstitials preferentially reside at the boundaries rather than in the SiO 2 bulk. The results elucidate the nature of the SiO x microstructure and the complex interactions between the metal electrodes and the switching oxide, each of which is critically important for further materials engineering and the optimization of ReRAM devices.

Zbog svojih jedinstvenih i rijetkih kolekcija, Specijalne zbirke Nacionalne i univerzitetske biblioteke Bosne i Hercegovine (NUBBiH) su nezamjenjiv izvor za mnogostruke istraživačke projekte i naučne radove. Već dugi niz godina NUBBiH ulaže napor da putem svojih projekata naučnoj zajednici pobliže predstavi vrijedne kolekcije Specijalnih zbirki. Da bi se korisnicima osigurao brži i lakši pristup građi, a ujedno i zaštitili originalni dokumenti od njihovog daljeg propadanja, građa koja je obuhvaćena projektima digitalizira se i prezentira kroz Digitalne kolekcije NUBBiH. U ovom radu predstavit ćemo jedan takav projekt, a to je projekt zaštite i prezentacije Arhiva poljičkih isprava iz Zbirke Aleksandra Poljanića te ćemo prikazati dosadašnje rezultate, kao i krajnje ciljeve ovoga projekta. = The Special Collections of the National and University Library of Bosnia and Herzegovina (NULBIH) are an irreplaceable source for multiple research projects and scientific papers. For many years, NULBIH has been strengthening efforts to present values of Special Collections to the scientific community through its projects. To provide users with faster and easier access to the material, and at the same time to protect the original documents from their further deterioration, the materials covered by the projects are digitized and presented through the Digital Collections portal of the National and University Library of BIH. In this article, we will present the ongoing project “Protection and presentation of the Poljica Documents Archive from the Collection of Aleksandar Poljanić” and so far, the results and ultimate goals of this project.