Résumé : Cette thèse porte sur l'investigation, par microscopies à effet tunnel (STM) sous ultra-haut vide (UHV) et à force atomique (AFM) à pression atmosphérique, de réseaux supramoléculaires sur différents types de surfaces, telles que: Au(111), Si(111)-B et HOPG, ainsi que sur l'étude de la synthèse en surface de nanostructures liées de manière covalente. Le premier chapitre présente l'état de l'art des interactions molécule-molécule non covalentes qui régissent l'auto-assemblage supramoléculaire et les méthodes pour obtenir des auto-assemblages covalents. Le deuxième chapitre présente des concepts théoriques, les montages expérimentaux, les procédures de préparation de surfaces propres et des pointes ainsi que les méthodes de des dépôts moléculaires utilisés sous ultra-vide et à pression atmosphérique. Le troisième chapitre est dédié aux résultats obtenus par STM dans le système UHV et à la comparaison de l'étude de l'auto-assemblage supramoléculaire des molécules dipolaires LdipCC sur les surfaces Au(111) et Si (111)-B. Sur la surface Au(111), les molécules LdipCC forment un réseau supramoléculaire poreux étendu qui est régi par des interactions molécule-molécule tandis que sur la surface de Si(111)-B, les molécules LdipCC s'auto-assemblent en un alignement parallèle homogène et étendu de dipôles moléculaires en raison du rôle significatif des interactions molécule-surface.. Le quatrième chapitre est dédié aux résultats obtenus dans les conditions ambiantes et étudiés par AFM en mode « Peak Force Tapping ». Deux types de molécules comportant des chaines alkyles et des groupements éthylène et époxy, ont été étudiés. Nous avons observé des systèmes auto-assemblés en réseaux bidimensionnels sur la surface HOPG. Le réseau supramoléculaire à base d'éthylène a été exposé à un recuit thermique tandis que le réseau supramoléculaire à base d'époxy a été exposé à la lumière UV. Les mécanismes proposés basés sur l'analyse des images AFM en topographie et en d'adhésion suggèrent qu'une réaction de cycloaddition en surface induite thermiquement et une polymérisation initiée par la lumière UV se sont produites sur la surface de HOPG. De cette manière, les réseaux auto-assemblés bidimensionnels sur la surface HOPG ont été convertis en auto-assemblages supra-moléculaires liés de manière covalente.

<p>A devastating earthquake (Mw 6.2) occurred on December 29, 2020,&#160; near the town of Petrinja, in Croatia, a few kilometers north of the Bosnian border with Croatia. The earthquake affected Bosnia and Herzegovina as well, and many buildings in northwestern Bosnia and Herzegovina were severely damaged. The main earthquake impact was preceded by two strong for-shocks, which shows a great resemblance to the Banja Luka earthquake of 1969. Seismic activity at the end of December 2020 and January 2021 was manifested through the occurrence of a large number of seismic events, namely: one earthquake of magnitude 6.2, two earthquakes of magnitude between 5.0 and 6.0, twenty-two earthquakes of magnitude between 4.0 and 5.0, sixty-six earthquakes of magnitude 3.0 and 4.0 and two hundred and seventy-seven earthquakes of magnitude between 2.0 and 3.0. This earthquake is a consequence of the movement of the Adriatic microplate and its interaction with the Eurasian tectonic plate. Its movement results in the creation of current seismicity in Croatia, Bosnia and Herzegovina, Italy, Montenegro, Serbia, Slovenia.</p><p>Today, analysis of the deformations of the Earth's crust plays an important role in research related to the entire seismic cycle. The phases of seismic cycles can be reliably estimated using time series of daily coordinates from continuously operating stations of the Global Navigation Satellite System (GNSS).</p><p>In this study, we used five time-series GNSS positions (Sarajevo, Pore&#269;, Ljubljana, Po&#382;ega, and Zadar), daily resolutions (24 hours) in the IGS14 reference frame, taken from Nevada Geodetic Laboratory through the website. We determined the coseismic displacement field of the Mw 6.2 Petrinja mainshock using downloaded the GNSS time-series as well as coseismic displacement field for all earthquakes of magnitude over 4. We processed data for the GNSS time series for the period from January 2016 to December 2020. GNSS stations are located at distances ~100 km to the ~250 km distances the epicenter of the Petrinja earthquake, of which the Pore&#269; station is the closest. JavaScript Object Notation (JSON) text format was used for processing all earthquakes in our study. JSON offset file is created based on the data downloaded from USGS (U.S. Geological Survey).</p><p>This paper, apply interactive processing in tectonics and seismology, presented offset in time series as a consequence of earthquakes. We have concluded that the cumulative movement of the Earth's crust is not only a consequence of large earthquakes but also the cause of many smaller accumulated movements caused by smaller earthquakes. The paper presents the contribution in the field of application of satellite positioning methods in geodynamic research and defines an approach that enables objective quantification of deformations of the Earth's crust in cases of seismic events. The earthquake occurred in a fault that extends approximately in the northwest-southeast direction and passes through Pokuplje near Petrinja and Glina. This fault is the boundary between two very different tectonic blocks, the Dinarides and the Pannonian Basin. Therefore, it can be said that the different stresses and displacements in these blocks are compensated through these blocks.</p>

We present a proof-of-concept study to assess whether deformable registration followed by tissue classification using machine learning (ML) is an effective method for the delineation of liver metastases in whole-body diffusion-weighted imaging (WB-DWI). Deformable atlas-based registration achieves good quality delineation of the liver (Dice coefficient > 70%) and out of three ML models random forest achieved the best F-1 measure for segmenting disease within the liver.

Background: The quality of healthcare and therefore primary healthcare and its measurement is a theoretical problem. However, its practical performance turned out to be even greater. However, we must always keep in mind the importance of not only primary healthcare as one of the key branches of the healthcare system, but above all its quality. Quality assessment is the first step in quality assurance and includes the analysis of structural, process and outcome variables. Objective: This article deals with that issue - assessment of the quality of work is one of the key elements in primary healthcare.. Methods: This is cross-sectional study about quality assessment of patient's satisfaction in PHC units in Bosnia and Herzegovina regarding AKAZ standards and rules. Results and Discussion:: Namely, primary healthcare, which operates at the municipal level and serves 10,000 to 50,000 inhabitants, must be carried out with quality, in order to raise the health standard in the country to a higher level. All countries, including ours, strive to provide high-quality healthcare services to residents with the available resources. With this idea, the Agency for Quality and Accreditation in Healthcare FBiH (AKAZ) was formed with its headquarters in Sarajevo. It is the competent authority in the field of improving the quality and safety of healthcare services. AKAZ offers a unique program to improve the quality and safety of healthcare services for healthcare centers, family medicine teams, hospitals and private health institutions in the Federation of Bosnia and Herzegovina. The agency was established to work in cooperation with healthcare professionals and help them improve standards of quality and safety of healthcare.The manner in which we will collect the data we need to assess the quality of work is in the form of a questionnaire. This directly addresses residents, healthcare service users. Only from them will we receive appropriate information on the functioning or non-functioning of the healthcare system. Conclusion: More precisely, we can directly conclude whether a problem that has appeared is a problem of the entire healthcare system (at the level of the municipality, canton, entity, state), or whether it is a problem of a narrower nature. Namely, the problem can also be at the level of the healthcare center or even the practicing doctor. Such data are of great use to us in order to improve the entire healthcare system, starting from the practicing doctor, the family medicine team, and so on all the way upward to the competent political authorities.