O presente trabalho objetivou caracterizar as notificacoes de receitas (nr), com prescricao de metilfenidato, em tres lojas de uma rede de farmacias do municipio de londrina, parana. A amostra caracterizada foi composta por 335 notificacoes de receitas retidas pelos estabelecimentos entre os meses de janeiro e julho do ano de 2010. Dentre as tres apresentacoes disponiveis no mercado, o medicamento ritalina® foi o mais prevalente, aparecendo em 82,7% das nr, assim como os pacientes do sexo masculino (76,7%) e as nr provenientes do setor privado (82,7%). Quanto a especialidade medica do prescritor e o periodo de retencao da prescricao, destacam-se respectivamente, a neurologia pediatrica (66,9%) e o mes de abril (20,6%). Foram consideras ilegiveis, 13,7% da amostra, e a presenca da denominacao comum brasileira apareceu em apenas 33,7% das nr. A dose diaria definida quanto ao sexo dos pacientes resultou em uma maior media para o sexo masculino (23,3 mg), e comparada a origem da nr, obteve-se a maior media para o setor privado (23,5 mg). A partir dos resultados encontrados, destaca-se que aspectos como a legibilidade e presenca da denominacao comum brasileira deveriam ser revistos pelos prescritores com o intuito de favorecer o preenchimento adequado das nr, promovendo assim, o uso racional de medicamentos. 10.5216/ref.v8i3.15801

Brain tumors are unique and heterogeneous group of tumors which face a variety of specialty, most oncologists, neurologists, and neurosurgeons. Due to its specific location, all brain tumors are malignant, regardless of their malignant potential, because any expansion process inside the skull, increasing intracranial pressure and the destruction of surrounding structures, which may cause neurological injuries, quantitative disturbances of consciousness or death.

Motion control systems represent a main subsystem for majority of processing systems that can be found in the industrial sector. These systems are concerned with the actuation of all devices in the manufacturing process such as machines, robots, conveyor systems and pick and place mechanisms such that they satisfy certain motion requirements, e.g., the pre specified reference trajectories are followed along with delivering the proper force or torque to the point of interest at which the process occurs. In general, the aim of force/torque control is to impose the desired force on the environment even if the environment has dynamical motion.

Introduction: Water can support the growth of different microorganisms which may result in contamination. Therefore, the microbiological examination is required for testing the hygienic probity of water. In the study of microbial composition of untreated, natural spring and mineral water differences in the presence and number of bacteria during the two periods, winter and summer, are detectable.Methods: In our study, we analyzed and compared the following parameters, specified in the Rulebook: total bacteria and total aerobic bacteria (ml/22 and 37°C), total Coliform bacteria and Coliforms of fecalorigin (MPN/100ml), fecal streptococci as Streptococcus faecalis  (MPN/100ml), Proteus spp (MPN/100ml), and Pseudomonas aeruginosa (MPN/100 ml) Sulphoreducing Clostridia (cfu / ml). The paper is a retrospective study in which we processed data related to the period of 2005-2009 year. While working, we used the descriptive-analytical comparative statistical treatment.Results: The obtained results show statistically significant differences in the microbial composition of untreated water in the two observed periods,Conclusions: Findings were consequence of different weather conditions in these periods, which imply a number of other variable factors.

Introduction: The aim of the research was to determine the effect of breakthrough pain (BTP) on heart and lung function in patients whose cancer pain had been treated with strong opiates.Methods: A prospective study was conducted on 80 patients who were treated in recumbent patients’ hospice of Palliative Care Centre (hospice) University Clinical Centre Tuzla. The effect of pain breakthrough onheart function was monitored by blood pressure and pulse measuring outside. The effect on respiratory function was monitored by measuring the respiration number with SpO2 and pCO2 and pO2 capillary blood valuesoutside, during and after relieving pain breakthrough.Results: Mean value for Karnofsky score for patients upon admission was 47.13 ± 11.05 and on discharge 51.25 ± 11.73. The total number of pain breakthroughs for patients within the 10 days of the treatment was1396. During the pain breakthrough the mean of systolic pressure was 133.1 mmHg and it was statistically significantly higher than the mean of systolic pressure measured after BTP relief with oral morphine. Themean of diastolic pressure measured outside of pain breakthrough was 75.9 mmHg and after the BTP relief it was 72.9 mmHg. The mean pulse outside of pain breakthrough was 92.7 heartbeats per minute and afterthe BTP relief 8 9.1 heartbeats per minute.Conclusion: Pain breakthrough leads to pulse acceleration, increased systolic and diastolic blood pressure and it also affects respiratory function by accelerating the respiration

Next generation transport network is characterized by the use of in-band signaling, where Internet Protocol (IP) packets carrying signaling or media information are mixed in transmission. Since transport resources are limited, when any segment of access or core network is congested, IP packets carrying signaling information may be discarded. As a consequence, it may be impossible to implement reachability and quality of service (QoS). Since present approaches are insufficient to completely address this problem, a novel approach is proposed, which is based on prioritizing signaling information transmission. To proof the concept, a simulation study was performed using Network Simulator version 2 (ns-2) and independently developed Session Initiation Protocol (SIP) module. The obtained results were statistically processed using Statistical Package for the Social Sciences (SPSS) version 15.0. Summarizing our research results, several issues are identified for future work.