In the observed decade, 1300 cases of trichinellosis were registered in Vojvodina, including three with a lethal outcome. The lethality was 0.23%. The incidences of trichinellosis ranged from 2.2/100,000 to 13.6/100,000. The rate of incidence depends both on the number of epidemics and the size of the epidemic reported in a year. Most incidences were reported in 2002 and 2005, as a consequence of the spread of trichinellosis through the purchase of infested food. The epidemic of trichinellosis in the Middle Banat district that started at the end of 2001 is considered to be the largest outbreak of human trichinellosis in Vojvodina, when 313 people got sick. In most of the cases the affected people reported they had eaten smoked sausages. The high incidence of trichinellosis in 2005 was a consequence of three thrichinellosis outbreaks that had been spreading through infested smoked sausages originating from illegal production and trade. More than 200 cases of trichinellosis were reported in Vojvodina. Today, Srem is still considered a hyperendemic area, because more than 30% of all the epidemics occur in this area. The available data indicate that trichinellosis is spread all over Vojvodina and that the absence of control results in the risk from the incidence of human trichinellosis. In many European countries the epidemiological situation is stable, but in our country trichinellosis is the most important zoonotic disease. This unstable epidemiological situation is the consequence of the widespread infection, culinary customs, and the fact that there is inadequate control of meat and meat products in households and illegal trade.

Serotonin or 5-hydroxytryptamine (5-HT), is a monoamine neurotransmitter synthesised from L-tryptophan in serotonergic neurons and enterochromaffin cells of the gastrointestinal tract. This neurotransmitter is widely distributed in the animal and plant kingdom and regulates some central and peripheral functions through several types of specific serotonergic (5-HT) receptors. Since it is known that the effect of serotonin, especially in pathological conditions, is very important, we believe that determining the types of receptors for this substance would make it possible to use their agonist or antagonists, which would undoubtedly enhance the pharmacotherapy of functional disruption of the small intestine in broilers. Investigations were carried out on isolated smooth muscle strips of the circular and longitudinal layer of the broiler small intestine (strip dimension 3-4 mm x 2 cm). The muscle strips were placed in an isolated organ bath. The mechanical activity of the preparations was recorded via an isotonic force transducer coupled to a pen recorder. This was done following the addition of serotonin (nonselective 5-HT agonist), 8-OH-DPAT (selective 5-HT1A agonist) and spiroxatrin (selective 5-HT1A antagonist). The sensitivity of the tissues to acetylcholine was tested before starting the experiments. Using the obtained results, it can be concluded that 5HT1A type receptors are present in smooth muscles of the broiler small intestine, duodenum and ileum, especially in the longitudinal smooth muscle layer which reacted with contractions even to low serotonin concentration (10-6), but not in the jejunum.

Nitrofurans are synthetic broad-spectrum antimicobial agents that are often used in commercial animal production because of their excellent antibacterial and pharmacokinetic properties. However, nitrofurans and their metabolites have been shown to have potentially carcinogenic and mutagenic characteristics which has led to a ban on the use of nitrofurans in preventive and therapeutic treatment of animals used for food production. Metabolites of nitrofurans that can be determined after their application are: a metabolite of furazolidone, furaltadone metabolite, a metabolite of nitrofurantoin and nitrofurazone metabolite. The presence of residues of nitrofuran antibiotics in meat, fish and shrimps, and milk and eggs originating from countries outside the European Union is monitored and recorded by the RASFF system of the European Union. Furthermore, since nitrofurans are used in some countries as prophylactic agents and growth promoters, it is necessary to carry out constant control of various types of food of animal origin, in order to reduce to the minimum potential carcinogenic and mutagenic effects of these supstances for the health of consumers. In Bosnia and Herzegovina, there is no permanent control of nitrofurans in food of animal origin. The provisions of the „Regulation on the maximum allowable amounts of veterinary drugs and pesticides in products of animal origin", published in the Official Gazette of Bosnia and Herzegovina state the prohibiting of the use of certain veterinary drugs in animals intended for human consumption, including nitrofurans. The European Union has established the minimum required limit (MRLP) for performance which is 1 μg/kg of nitrofurans for edible tissues of animal origin. Taking all this into account, methods for nitrofurans detection should be accreditated and validated, both for screening and confirmatory methods, and further research into the presence of nitrofurans in food of animal origin in Bosnia and Herzegovina should be performed.