The goal of a coach is to prepare an appropriate model of training for their athletes and provide adequate and healthy way of regulating their body weight. On a sample of 32 judo athletes of younger senior age on the territory of the city of BanjaLuka and municipality of Laktasi, a specific model of training was applied for a period of ten weeks and the judo athletes were divided into two groups. One group was the control group, and other was experimental. The experimental group has implemented 60 training sessions, of which 40 judo trainings (25 technical-tactical and 15 situational judo trainings-randoria) and 20 trainings with the load (50-80% of 1 RM). In this period, the control group worked only judo trainings or 40 training sessions. Statistical analysis of the results is divided into two segments the descriptive statistics and application of methods of the inferential statistics. The initial and final measurements of body composition of groups were conducted by the bioelectrical impedance(BIA method), and the two-component(2C) model was used for this work which divides the whole body in total body fat (fat mass) and non-fat body mass (fat-free mass). From the field of descriptive statistics on the level of the entire sample, the central and dispersion parameters were calculated. The methods of inferential statistics used in this study were t-test for dependent and independent samples and analysis of covariance. The values of percentage of body fat in the experimental group, which was exposed to a specific training process for a period of ten weeks, were notably statistically reduced during this period.Value of body fat from an initial 23.10% after the training protocol, decreased to 20.41%, on the .01 level of significance. Values of the percentage of body fat in the control group were kept on the same, higher level than recommended for judo, even after the training, pointing to the effects of their less successful training protocol.

Cilj ovog istraživanja bio je da utvrdi razlike na polju funkcionalnog fitnesa kod muškaraca starijih od 60 godina. U istraživanje je bilo uključeno 272 ispitanika. Sve ispitanike smo podijelili u pet starosnih kategorija, i to: 60–64 godine bilo je 90 ispitanika (33%), 65–69 godina, 70 ispitanika (26%), 70–74 godine, 50 ispitanika (18%), 75–79 godina, 41 ispitanik (15%) i preko 80 godina starosti bio je 21 ispitanik (8%). Svi ispitanici su proveli bateriju testova pod nazivom senior fitnes test. Test se sastoji od šest mjera fizičkog fitnesa: 1) pokretljivost ramena, 2) pretklon na stolici, 3) osam stopa, 4) ustajanje sa stolice za 30 sekundi, 4) fleksija u zglobu lakta, 5) dvominutni step test. Body mass index pokazuje da su svi ispitanici prekomjerne tjelesne težine bez obzira kojoj starosnoj kategoriji pripadaju. Kod fleksibilnosti ne postoji statistički značajna razlika (p > 0,05) između ispitanika različite starosne dobi nakon 60. godine starosti. Ispitanici se najviše razlikuju po pitanju snage kako donjih, tako i gornjih ekstremiteta. Primijećeno je opadanje snage sa procesom starenja tako da se ispitanici starosne dobi 60-64 godina statistički značajno razlikuju u snazi donjih ekstremiteta (p < 0,05) od ispitanika starih 70–74 i 75–79 godina. Najveća heterogenost zabilježena je u parametrima aerobne izdržljivosti, gdje rezultati progresivno opadaju od 60 godine, gdje su zabilježene najveće vrijednosti (78,60 ± 42,00) do 80. godine starosti (73,68 ± 35,62). U ovoj studiji smo utvrdili da je došlo do povećanja količine masnog tkiva, smanjenja nivoa mišićne aktivnosti, kao i smanjenja mišićne snage i izdržljivosti procesom starenja.

Bovine tuberculosis is a chronic disease of a zoonotic character that occurs in cattle and a wide range of domestic and wild animals. In this paper, bovine tuberculosis caused by M. caprae in six small household herds in Bosnia and Herzegovina was described. For the identifi cation of the disease and determination of the causative agent comparative tuberculin skin test (TST), pathomorphology, microbiology and molecular methods were applied. Twenty-eight cows from fi ve households from the Livno region (25/28 animals) and one household from the Vitez region (3/28 animals) were euthanized after being found positive by the comparative TST test. Eleven animals from fi ve households from the Livno region (9/11 animals) and one household from the Vitez region (2/11 animals) were subject to fi eld necropsy, and lesions consistent with tuberculosis were observed on the lymph nodes of the thoracic cavity and lungs in all carcasses. Histopathologic examination by hematoxylin and eosin staining confi rmed the presence of specifi c granulomatous lesions, while Ziehl- Neelsen staining demonstrated the presence of very few acid fast bacteria. Mediastinal lymph nodes from seven necropsied animals (two animals from the Vitez region and fi ve animals from fi ve fl ocks from the Livno region) were submitted for bacteriology. Acid fast bacteria from fi ve out of the seven submitted samples from one animal from the Vitez region and four animals from four households from the Livno region were isolated. All isolates were identifi ed as M. caprae. By MIRU typing we found two different M. caprae genotypes, unique to Bosnia and Herzegovina. Our fi ndings represent the fi rst evidence of bovine tuberculosis caused by M. caprae in Bosnia and Herzegovina.

The paper presents a comparison of the possibility and complexity of the calibration process of two microsimulation models. The first model CORSIM is simple for use while the second named S-Paramics is more complex software. For research purposes, a model of street network with defined geometry (number, width and purpose of lanes) has been made. The volume and distribution of traffic as well as the data about traffic signals were input in the models. Numerous simulations were performed, first with the default parameters of models, and then with the calibrated parameters. Both programs have resulted in very good prediction of the intersection capacity and discharge volumes. However, for the calibration of speed more time and effort have been made in S-Paramics in which the average speed may be higher than the defined free-flow speed. This can present a problem in determining the level of service and comparing the S-Paramics results with other simulation models and analytical method results. On the other hand S-Paramics has greater capabilities than CORSIM (roundabouts modelling, dynamic traffic assignment, opportunity to interact with traffic signals...). Thus, for each specific task, one should carefully choose an appropriate program which would result in necessary and reliable output data with minimum effort and time consumed.

Introduction: Alopecia areata (AA) is disease characterized by focally, nonscarring hair loss on the scalp or other parts of the body. It affects 1-2% population of both genders and occurs at all age groups. The etiology is unknown, although most evidence supports the hypothesis that AA is a T-cell-mediated autoimmune disease of the hair follicle and that cytokines play an important role. Objective: The aim of our study was to evaluate serum concentrations of IL-1α and IL-1β in patients with AA and healthy subjects and also to asses a possible association between these cytokines and duration of the disease. Methods: Forty six patients with AA and 20 healthy controls were enrolled in the study. Serum concentrations of IL-1α and IL-1β were measured using enzyme-linked immunoassay techniques. Results: The serum level of IL-1α in patients with AA was significantly higher than that in the control group (4.34±0.86 pg/mL vs 3.66±0.35 pg/mL, respectively). IL-1β levels were greater in patients with AA than in controls (2.35±0.17 pg/mL vs 2.24±0.30, respectively) but the difference was not significant (p>0.05). No correlations were found between duration of disease and the serum levels of IL-1α and IL-1β. Conclusion: Our results have demonstrated the importance of determining IL-1a concentration in serum in patients with AA. This research could contribute to the interpretation of insufficiently well known views of the pathogenesis role and significance of IL-1α in AA. Streszczenie Wstep: Łysienie plackowate to choroba charakteryzująca sie ogniskowym, niebliznowaciejącym lysieniem skory glowy lub tez innych okolic ciala. Choroba ta dotyka 1-2% populacji, bez predylekcji plci ani tez wieku. Etiologia choroby pozostaje nieznana, jednakze najwiecej dowodow potwierdza hipoteze, ze AA jest chorobą autoimmunologiczną mediowaną za pomocą komorek T, zajmującą korzen wlosa oraz ze cytokiny pelnią w tym procesie wazną role. Cel: Celem naszego badania bylo oszacowanie stezenia w surowicy interleukin: IL-1α i IL-1β u pacjentow z AA oraz u osob zdrowych by wykazac mozliwe związki pomiedzy tymi cytokinami a dlugością trwania choroby. Metody: Do badania zakwalifikowano 46 pacjentow z AA oraz 20 osob zdrowych. Stezenia cytokin IL-1α i IL-1β byly mierzone za pomocą techniki EIA. Wyniki: Poziomy IL-1α u chorych na AA byl znacznie wyzszy niz ten w grupie kontrolnej (4.34±0.86 pg/mL vs 3.66±0.35 pg/mL, odpowiednio). Poziomy IL-1β byly wieksze u pacjentow z AA niz w grupie kontrolnej (odpowiednio 2.35±0.17 pg/mL vs 2.24±0.30) jednak statystycznie nieistotne (p>0.05). Nie znaleziono korelacji pomiedzy trwaniem choroby a poziomami interleukin IL-1α i IL-1β w surowicy krwi. Wnioski: Nasze wyniki badan dowodzą wagi pomiaru stezenia IL-1a w surowicy krwi osob chorych na AA. To badanie moze przyczynic sie do nie do konca poznanej roli IL-1α w patogenezie oraz odkryciu pelnego znaczenia w Alopecia Areata.