This work gives the method of transient time determination of the belt conveyor in the case of its start up in the example of a belt conveyor for ore at the open pit “Veliki Krivelj” with capacity of 2000 t/h. The analysis was made by calculation procedure and it represents a universal calculation method of conveyor belts whose results are indispensable for verification the reliable operation of selected electric motors during the start up of belt conveyor. Also, technical characteristics of all components of drive units are given as well as their layout.

1 MS Program in Mathematics Education, Richard W. Riley College of Education and Leadership, Walden University, 155 Fifth Avenue South, Minneapolis, MN 55401, USA 2Department of Mathematical Sciences, United Arab Emirates University, P.O. Box 17551, Al-Ain, United Arab Emirates 3 Department of Mathematics, University of Rhode Island, Kingston, RI 02881, USA 4Departament de Matematica Aplicada, IUMPA, Universitat Politecnica de Valencia, Edifici 7A, 46022 Valencia, Spain

The most significant individual prognostic factor for those suffering from NSCLC is cancer invasion of regional lymph nodes, which depends on pathomorphological characteristics of the primary disease. Cellular and histological atopy of the changed tissue means good predispositions for an early lymph invasion and lymphonodular metastasizing. The aim of the paper: a standard statistical analysis which includes frequency of the degree of malignant change differentiation, metastasizing in stages N1 and N2 and the statistical dependence of the mentioned variables. Patients and methods: a retrospective analysis covered 331 patients who underwent a surgical procedure after they had been diagnosed with NSCLC and it was also based on the definite pathohistological postresectional results which included the above mentioned characteristics in a descriptive manner. Results: the average age of the total number of patients was 62.69 ± 7.47. Males were more numerous than females (4.7:1). There was a significant statistic correlation between the development of the disease and the age (ch 2 test = 493.65; p< 0.05), as well as a significant difference of age in relation to gender (p< 0.05). G2 stage of the disease was the most frequent, with participation of 58.00%, and there was a significant statistical correlation between developing the disease and the level of differentiation ( ch 2 test= 248.13; p<0.05). The invasion of the node N1 was 44.61% and of N2 4.53%. There was a statistically significant correlation between N1 and N2 metastases and the level of differentiation of cancer (ch 2 test =24.74; p=0.00 vs. ch 2 test = 16.37; p=0.01). Conclusion: the domination of G2 stage and statistically significant correlation between the levels of differentiation and regional lymphonodular invasion.

Introduction. Chronic,low-grade infl ammation is important in the development and progression of type 2 diabetes mellitus (T2DM). Indicators of increased infl ammatory activity include elevated values of circulating acute phase proteins like C-reactive protein (CRP) and fi brinogen. The aim of the study was to test sex-related differences in CRP and fi brinogen blood levels in T2DM patients. Patients and Methods. The cross-sectional study included 40 T2DM patients, both sexes (19 males and 21 females), median age 70 (36-90) years. Patients were hospitalized at the Clinic of Endocrinology, Clinical Center University of Sarajevo. The fasting glucose levels, glycated haemoglobin, fi brinogen and CRP in the blood of T2DM patients were determined by standard laboratory methods. The data were analysed by statistical software SPSS 19. Results. The median values of CRP and fi brinogen in blood were not statistically different between female and male T2DM patients, although values had tendency to be higher in female patients [17.30 mg/L (3.40-61.35) vs. 9.60 mg/L (3.50-28.90); p=0.573]; [5.70 g/L (4.20-6.35) vs. 3.80 g/L (3.60-6.00); p=0.078]. A positive correlation between CRP and fi brinogen was found in samples from female T2DM patients (rho=0.606;p<0.01). Conclusion. Elevated CRP and fi brinogen indicate the presence of infl ammation in T2DM patients. Female patients had higher values of both infl ammatory markers in blood in comparison to males, but we did not prove statistically signifi cant sex-related differences.

Karol Visinko e autrice del instrumentario didattico in questo manuale che rapresenta un programma formativo che offre la possibilita di conoscere meglio la citta di Fiume, di viverla meglio, di sentirla e di custodirla dimostrando tanto amore per tutto quello che la rende particolare, diversa e unica. Il manuale La mia Fiume puo risvelgliare la curiosita per tante ricerce del passato e dell´ oggi fiumano nelle scuole elementari di Fiume.

U radu je predstavljena zamjena dijela sustava turbinske regulacije proizvodnih jedinica A i B HE Cakovec. U uvodu su navedeni bitni razlozi za zamjenu dijela sustava turbinske regulacije. Nakon toga predstavljeni su podsustavi sustava turbinske regulacije: turbinski regulator, upravljanje nizvodnim zatvaracima, mjerenja razina vode i elektrohidraulicki dio sustava turbinske regulacije. Također je predstavljeno mjerenje razina vode s hardverskom strukturom posebno prilagođenom za ova kontinuirana mjerenja. Posebna pozornost posvecena je dodatnoj funkciji turbinskog regulatora za nadzor kvarova u sustavima pozicioniranja privodnog i radnog kola. Dodatno su opisana HIL ispitivanja (Hardware in the Loop testing) sustava turbinske regulacije koja su provedena prilikom tvornickih ispitivanja i navedene njihove prednosti. Opisan je registrator prijelaznih pojava i događaja. Na kraju je dan osvrt na primopredajna ispitivanja, te redoslijed projektiranja i izvođenja radova na HE Cakovec.

Proton NMR spectroscopy and cyclic voltammetry have been applied to study the stability of three gold(III) complexes with L-histidine-containing peptides, [Au(Gly-L-His-N,N’,N’’)Cl]NO3.1.25H2O (Au1), [Au(L-Ala-L-His-N,N’,N’’)Cl]NO3.2.5H2O (Au2) and [Au(Gly-Gly-L-His-N,N’,N’’,N’’’)]Cl.H2O (Au3) under physiologically relevant conditions. It was found that tridentate coordination of Gly-L-His and L-Ala-L-His dipeptides, as well as tetradentate coordination of Gly-Gly-L-His tripeptide in Au1, Au2 and Au3 complexes, respectively, stabilized +3 oxidation state of gold and prevented its reduction to Au(I) and Au(0). No release of the coordinated peptides from Au(III) was observed under these experimental conditions. Considering remarkable stability of Au1, Au2 and Au3 complexes, their cytotoxic activity was evaluated by MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay toward five human tumor cell lines, MCF-7 (human breast adenocarcinoma), HT-29 (human colon adenocarcinoma), HeLa (human cervix carcinoma), HL-60 (human promyelocytic leukemia), Raji (human Burkitt’s lymphoma) and one human normal cell line MRC-5 (human fetal lung fibroblasts). While the cytotoxic activity of Au1, Au2 and Au3 against investigated human malignant cell lines was strongly cell line dependent, none of these complexes was cytotoxic against normal MRC-5 cell line. This study can contribute to the future development of gold(III)-peptide complexes as potential antitumor agents.