There is a need for classifying and conserving local apple cultivars from two main regions in Bosnia and Herzegovina (BH P < 0.001). Analysis of the genetic structure indicates that overall, approximately half of the local apple cultivars from Sarajevo and eastern Bosnia (52% and 45%, respectively) grouped in the RPP1 consisting mainly out of international reference cultivars, whereas the other half grouped in the RPP2 with traditional B&H reference cultivars. Both neighbor joining (NJ) cluster analysis based on Bruvo genetic distance and factorial correspondence analysis (FCA) confirmed the results of the genetic structure analysis. The molecular data show that both apple accessions from Sarajevo and from eastern Bosnia represent an interesting source of diversity, which needs to be conserved.
In order to identify possible mislabeling of the apple accession maintained ex situ in Srebrenik and to gain insight into the genetic structure of the conserved germplasm, 14 accessions from the collection were genotyped using 10 SSR (Simple Sequence Repeats) markers. Obtained SSR profiles were then added to an existing database constructed for previously characterized 24 traditional and 13 international, reference apple cultivars maintained at the same collection. Bayesian analysis implemented in the STRUCTURE program grouped 42 out of 51 analyzed apple accessions (38 traditional and 13 international) into three RPPs (reconstructed panmictic populations) with probability of membership qI higher than 75%. Almost all international, reference cultivars grouped in RPP3, whereas traditional B&H cultivars from the Srebrenik collection grouped in all three RPPs. Large and significant differentiations between all three individual RPPs were detected through the analyses of molecular variance and confirmed with FCA (factorial correspondence analyses). NJ cluster analysis, based on the Bruvo genetic distance, revealed that out of 38 traditional B&H apple cultivars, analyzed in the study, ‘Ljepocvjetka’, ‘Bobovec’ and ‘Bobovec J’ grouped closest to the international reference cultivars. Available date indicates that unlike a large number of B&H apple cultivars which were introduced during the reign of the Ottoman Empire, ‘Ljepocvjetka’ and ‘Bobovec’ were probably introduced at a later date. Cluster analyses also enabled the detection of one synonym and three homonyms within the collection. In four cases, previously conducted identification based on phenotypic analyses was confirmed by genetic analyses. Results of the structure analyses indicate a heterogeneous genetic structure of the analyzed accessions. This characteristic of the B&H apple germplasm could be useful for future breeding programs.
The aim of this paper was to pilot test the L2MSS among Croatian university students using the motivation questionnaire developed by Taguchi et al. (2009). This study attempted to validate subscales of the Taguchi et al. (2009) questionnaire in a Croatian context and provide a basis for further investigation of the L2MSS. A total of 110 first year students, who were non- English majors from the University of Zadar, participated in the pilot study. The results of the factor analysis show that the items tested in each subscale had salient loadings and showed satisfactory internal consistency. It can be concluded that the sub-scales can be used on a larger sample for further studies and research on the L2MSS.
Karol Visinko e autrice del instrumentario didattico in questo manuale che rapresenta un programma formativo che offre la possibilita di conoscere meglio la citta di Fiume, di viverla meglio, di sentirla e di custodirla dimostrando tanto amore per tutto quello che la rende particolare, diversa e unica. Il manuale La mia Fiume puo risvelgliare la curiosita per tante ricerce del passato e dell´ oggi fiumano nelle scuole elementari di Fiume.
U radu je predstavljena zamjena dijela sustava turbinske regulacije proizvodnih jedinica A i B HE Cakovec. U uvodu su navedeni bitni razlozi za zamjenu dijela sustava turbinske regulacije. Nakon toga predstavljeni su podsustavi sustava turbinske regulacije: turbinski regulator, upravljanje nizvodnim zatvaracima, mjerenja razina vode i elektrohidraulicki dio sustava turbinske regulacije. Također je predstavljeno mjerenje razina vode s hardverskom strukturom posebno prilagođenom za ova kontinuirana mjerenja. Posebna pozornost posvecena je dodatnoj funkciji turbinskog regulatora za nadzor kvarova u sustavima pozicioniranja privodnog i radnog kola. Dodatno su opisana HIL ispitivanja (Hardware in the Loop testing) sustava turbinske regulacije koja su provedena prilikom tvornickih ispitivanja i navedene njihove prednosti. Opisan je registrator prijelaznih pojava i događaja. Na kraju je dan osvrt na primopredajna ispitivanja, te redoslijed projektiranja i izvođenja radova na HE Cakovec.
Introduction. Information on antibiotic utilization in the Republic of Srpska is limited. The aim of this study was to analyze antibiotic utilization in the community from 2007 to 2011 and to compare this data with antibiotic use in other European countries. Materials and Methods. We did a population-based study to analyze systemic antibiotic utilization by an outpatient population using Anatomical Therapeutic Chemical/Defi ned Daily Dose methodology. The results were expressed as the defi ned daily dose (DDD) per 1000 inhabitants per day. The data were obtained from the annual reports of the Agency for Drugs and Medical Devices of the Republic of Srpska and Public Health Institute. Results. Outpatient use of systemic antibiotics ranged between 21.51 DDD in the year with the highest use (2010) and 17.01 DDD in the year with the lowest use (2011). Penicillins were the most frequently prescribed antibiotic group, and amoxicillin was the most frequently prescribed drug. Cefalexin was the most frequently prescribed cephalosporin. Increased use of a second-generation cephalosporin, cefuroxime constituted almost a third of cefalexin consumption in 2011. Second-generation quinolones, mostly ciprofl oxacine, accounted for about 70% of total quinolones consumption, with rising third-generation drugs also in proportion to the increasing use. Erythromycine was the most frequently used macrolide, followed by long-acting azithomycin. Conclusion. Outpatient use of systemic antibiotics in the Republic of Srpska, at about 19 DDD, does not exceed that in Europe. As in other European countries, a shift between generations of drugs was noted for antibiotic use. Additional studies, including monitoring of seasonal variation impact on antibiotic use, are needed.
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