Results The study included 50 patients, 31 male (62%), aged 43 ± 13 years. Median time from hospital to ICU admission was 1 day (range 1-2). Sixteen patients (30%) presented with one or more chronic medical condition: 8 (16%) with chronic lung disease, 5 (10%) with chronic heart failure, and 3 (6%) with diabetes mellitus. Thirty-two (64%) were obese. Forty-eight patients (96%) experienced acute respiratory distress syndrome (ARDS), 28 (56%) septic shock, and 27 (54%) multiorgan failure. Forty-five patients (90%) were intubated and mechanically ventilated, 5 received non-invasive mechanical ventilation, 7 (14%) high-frequency oscillatory ventilation, and 7 (14%) renal replacement therapy. The median duration of mechanical ventilation was 7 (4-14) days. Hospital mortality was 52%.

Outdoor pig farming include free access to outdoor area and wide use of natural resources of soil and plants in which animals can express their natural behavior. Some management practices that may improve welfare such as outdoor rearing, holding in groups, use of bedding or other housing systems in which it is difficult to implement good sanitation may increase risk to exposure of pigs to the pathogens from the environment. Presence of pathogens or their vectors in outdoor areas in combination with poor environmental conditions may result in high prevalence of various infectious or parasitic diseases, many of which may be zoonotic. Difficulties in implementation of common biosecurity measures and health management principles in outdoor farming impede effective control of diseases. Use of breeds or strains which are adapted to harsh environmental conditions and exhibit favorable disease resistance such as local breeds or their crossbreds, appropriate feeding including plants and fungi that have detrimental effect on pathogens (parasites), and grazing management with integrated use of medicaments (anthelmintic) can be additional methods of controlling diseases in outdoor farming. The common health problems in outdoor pig farming system and their potential impact on human health are reviewed in this paper.

In this highlight we briefly review several of our recent theoretical studies focused on how the interplay between the chemical and the van der Waals interactions determines the bonding mechanism of several chemically functionalized π-conjugated organic molecules on non-magnetic and magnetic surfaces. In particular, we focus on the issue how to tailor the strength of the interaction between such π-conjugated organic molecules with a substrate of choice such that the nature of the molecular bonding has the specific features of the physisorption or chemisorption processes. Furthermore, we show how the precise control of these binding mechanisms allows us to design specific electronic and magnetic properties of hybrid organic-metallic interfaces.