Lessons from previous experiences are often overlooked when deploying security-sensitive technology in the real world. At the same time, security assessments often suffer from a lack of real-world data. This appears similar to general problems in technology assessment, where knowledge about (side-)effects of a new technology often only appears when it is too late. In this context, the paradigm of new technologies as social experiments was proposed, to achieve more conscious and gradual deployment of new technologies, without losing the ability to steer the developments or make changes in designs. In this paper, we propose to apply the paradigm of new technologies as social experiments to security-sensitive technologies. This new paradigm achieves (i) inherent attention for the ethics of deploying security-sensitive systems in the real world, and (ii) more systematic extraction of real-world security data and feedback into decision making processes.

Abstract OBJECTIVE: Anomalies of vertebrobasilar vessels arise as early embryonal developmental deteriorations. The majority of them concern the position, origin and shape of the basilar artery. Therefore the present study was carried out to find out the variations in position and shape of the basilar artery using Magnetic Resonance Imaging and CT Angiography. MATHERIAL AND METHODS: The study included 130 consecutive patients, adults of both sexes, treated in UKC Tuzla. Patients were divided into two groups. In one group (100) were patients without aneurysm in the vertebrobasilar tree, and in the second group (30) patients with aneurysm. RESULTS: Three types of variations in the shape of basilar artery were recorded: those with arched course, S-shaped course, and the straight course type. All the three types are approximately of the same percentage prevalence in the group of subjects without aneurysm in the vertebral-basilar tree, as well as in the group with aneurysm. Basilar artery at 89.33% of respondents was located in medial or in paramedial position. CONCLUSION: Attention is drawn to the practical importance of such variations as a possible source of diagnostic errors during cerebral arteriography. We highlight the morphological aspects of the basilar artery, the knowledge of which would help neurosurgeons safely diagnose, as well as plan and execute vascular bypass and shunting procedures for the treatment of stenosis, aneurysms and arteriovenous malformations.

Abstract: Measuring procedure of achieving room acoustic quality parameters with impulse response is usually used as the basis for acoustical measuring PC based software. The objective parameters: clarity (C), definition (D) and ratio between reflected and direct energy (R) are defined with reflected, direct and total energy of sound. The relations are set in order to enable estimation of other parameters based on measurement of only one energy parameter. Based on measurements in two architectural identical, but according to acoustic characteristics two different rooms, and additional analysis and calculations connected with number of people in a hall, objective parameters are evaluated according to earlier adopted optimal conditions involving certain deviations from the values.

Kronicna bubrežna bolest (HBB) je važan javno-zdravstveni problem (1). Prema definiciji KDIGO (Kidney Disease: Improving Global Outcomes) HBB je definirana kao strukturno ili funkcionalno ostecenje bubrega, koje traje >3 mjeseca, s posljedicama za zdravlje i klasificirana je na osnovi uzroka, kategorije glomerularne filtracije i kategorije albuminurije (2). HBB ima nekoliko stadija, a posljednji, terminalni stadij ili end-stage of renal disease (ESRD) odgovara uremiji s glomerularnom filtracijom 90 dana se također povecala i u 2011. godini iznosila 123,1 (3). Također, i u drugim zemljama koje vode renalni registar, zabilježen je porast incidencije i prevalencije pacijenata s ESRD. U svijetu je, u odnosu na modalitet tretmana zamjene bubrežne funkcije u razdoblju 2001.-2010. godina, bila najzastupljenija HD (68,5-69,2 %), zatim transplantacija bubrega (22,5-23,1 %), te peritonejska dijaliza (8,3-8,5 %) (4). U Bosni i Hercegovini u razdoblju 2006.-2011., HD je najucestalija metoda zamjene bubrežne funkcije s ucestaloscu UCINAK INTRADIJALIZNOG PROGRAMA VJEŽBANJA NA KVALITETU ŽIVOTA I FIZICKE MOGUCNOSTI U HEMODIJALIZIRANIH PACIJENATA

Background Inflammatory bowel disease (IBD) is associated with a defective intestinal barrier and enhanced adaptive immune responses against commensal microbiota. Immune responses against food antigens in IBD patients remain poorly defined. Methods IgG and IgA specific for food and microfloral antigens (wheat and milk extracts; purified ovalbumin; Escherichia coli and Bacteroides fragilis lysates; mannan from Saccharomyces cerevisiae) were analyzed by ELISA in the serum and feces of patients with Crohn's disease (CD; n = 52 for serum and n = 20 for feces), ulcerative colitis (UC; n = 29; n = 17), acute gastroenteritis/colitis (AGE; n = 12; n = 9) as well as non-inflammatory controls (n = 61; n = 39). Results Serum anti-Saccharomyces cerevisiae antibodies (ASCA) and anti-B. fragilis IgG and IgA levels were increased in CD patients whereas antibody (Ab) levels against E. coli and food antigens were not significantly different within the patient groups and controls. Subgroup analysis revealed that CD patients with severe diseases defined by stricturing and penetrating lesions have slightly higher anti-food and anti-microbial IgA levels whereas CD and UC patients with arthropathy have decreased anti-food IgG levels. Treatment with anti-TNF-α Abs in CD patients was associated with significantly decreased ASCA IgG and IgA and anti-E. coli IgG. In the feces specific IgG levels against all antigens were higher in CD and AGE patients while specific IgA levels were higher in non-IBD patients. Anti-food IgG and IgA levels did not correlate with food intolerance. Summary In contrast to anti-microbial Abs, we found only minor changes in serum anti-food Ab levels in specific subgroups of IBD patients. Fecal Ab levels towards microbial and food antigens show distinct patterns in controls, CD and UC patients.

Introduction: Complex etiology of osteoporosis include genetic, hormonal, environmental and nutritional factors. The aim of this study was to examine influence of coffee consumption on bone mineral density in postmenopausal women with estrogen deficiency in menstrual history.Methods: This prospective study included 100 postmenopausal women, aged 50-65 years living in Sarajevo area, with estrogen deficiency in their menstrual history. The controlled clinical trials were conducted. Two groups were formed (based on bone mineral density values). The examination group included 50 women who had osteoporosis, while the control group included 50 women without osteoporosis (osteopenia, normal bone mineral density). The lumbar spine and proximal femur bone mineral density was measured by Dual–Energy X–ray Absorptiometry using Hologic QDR-4000 scanner. Coffee drinking habits were assessed for each subject.Results: The average daily intake of coffee in women with estrogen deficiency in menstrual history was at 267.6 ml in the examination group and in the control group 111.6 ml. The difference in the average daily intake of coffee between the two groups was statistically significant (p < 0.001). There was registered significant correlation between intake of coffee and bone mineral density in examination (p < 0.01) and in control group (p < 0.05).Conclusion: This study indicates that coffee consumption is a risk factor for osteoporosis in postmenopausal women, aged 50-65 years living in Sarajevo area, with estrogen deficiency in their menstrual history. It was shown that the effects of coffee on bone mineral density are dose-dependent.