Paper compares numbers of publications published in indexed journals by authors from two cities, Tuzla and Sombor, approximately the same size during half of XX century, in order to determine how a newly opened medical school influences scientific research. Today, in Sombor only Faculty of Pedagogy exists (a part of Novi Sad University). From 1977-1979. number of publications from both cities was very low (only 2-4). Thirty years later, from 2009-2014. number of papers from Tuzla increased many fold (65-98 papers/year), while from Sombor remained low (0-4 papers/year) over the same period. Factors contributing to this phenomenon include: university environment, participation of most medical doctors in postgraduate research programs, exchange programs with other medical schools, both local and abroad, and significant financial support for medical students and research grants. Sombor enjoys no such financial support, and various temporary stimuli have failed to influence research and publishing significantly. Sombor doctors continue to present their observations and data at various meetings, but do not submit manuscripts to medical journals. Furthermore, the Sombor hospital administration does not support participation of physicians in graduate programs or doctoral studies. The rising number of published papers in Tuzla indicates that a larger medical center or hospital may not only inspire original research but may also guide busy physicians through process of publishing their manuscripts in medical journals. In this paper, details of postgraduate education at Medical School Tuzla are elaborated, and the idea of opening medical school in Sombor, first mentioned in the 1960s, is reiterated.

Breast cancer is a serious health problem. It is the most common cancer in women. The aim of this study was to estimate the concordance between ER, PR receptor and HER-2 immunohistochemistry assessment scores in pared CNB (core needle biopsy) and surgical specimens. Histological grade, oestrogen receptor (ER) status, progesterone receptor (PR) status, and human epidermal growth factor receptor-2 (HER2) status were evaluated in a blinded fashion in CNB and in surgical excision specimens. Absolute concordance rate between core needle biopsies and surgical specimens for histological grade was 50% with κ value (0,15) for ER 92% with κ value (0,79), PR 88% with κ value (0,73) and for HER2 96% with κ value (0,91). CNB can provide reliable information in evaluation of ER, PR and HER2 status in an invasive breast carcinoma. Ključne reči: breast cancer, core needle biopsy, oestrogen receptors, progesterone receptors, HER-2. Analiza odstupanja statusa hormonskih receptora i receptora za epidermalni faktor rasta 2 u uzorcima dobijenim iglenom biopsijom i hirurškim uzorkom kod obolelih od invazivnog karcinoma dojke Ljiljana Tadic Latinovic1, Zivka Eri2, Darko Jovic3, Aleksandra Salapura1, Jovan Culum3, Branislava Jakovljevic3, Ilija Baros1, Slavica Maric4 1 Department of Pathology, University Clinical Center of Republic of Srpska, Banja Luka, Republic of Srpska, Bosnia and Herzegovina 2 Canter for Molecular Genetics, Institute for Pulmonary Diseases, Sremska Kamenica, Republic of Serbia 3 Surgical Clinic “S-Tetik”, Banja Luka, Republic of Srpska, Bosnia and Herzegovina 4 International Medical CantersCentar za Radioterapiju Banja Luka, Banja Luka, Republic of Srpska, Bosnia and Herzegovina

The vehicle presents a dynamic system performing vibrations under the influence of certain stimulus. Information driver receives from the environment and the vehicle is: macro and micro texture of the road, vibrations and noise of the vehicle's subsystem and so on. The road is usually evaluated according to its macro and micro texture. Microroughness of the roads is of great importance for the study of vehicle's oscillatory movements, reliable computation of vehicle systems, safety etc. Therefore, a special attention must be given to them during the analysis of dynamics, strength and safety of the vehicle. Microroughness that characterize the microprofile of the road in longitudinal and transverse direction have random character and can be established by experimental study of the road with utilization of devices. Accordingly, a variety of devices have been developed for measurement of macro- and micro profiles of the road as well as numerous mathematical and experimental procedures, which with certain approximation satisfy the given requirements, and with the increasing use of computer technology.