Introduction: Myocardial perfusion imaging (MPI) is widely used in the evaluation of known and suspected coronary artery disease (CAD). Imaging of heart in stress and rest enables the comparison of myocardial uptake of radiotracer in proportion to the needs and coronary flow, which is used for detection of perfusion defects. Exercise stress and pharmacologic agents are used for the stressing purpose. Novel pharmacologic stressor regadenoson is A2A selective adenosine agonist, which selectively binds to the adenosine receptors in coronary arteries causing coronary dilatation. Materials and methods: We analyzed 50 myocardial perfusion studies performed with regadenoson as a pharmacologic agent that was injected before Tc99m-sestamibi in stress imaging. Stress and rest sets of images were evaluated for relative uptake of Tc99m-sestamibi in order to detect and characterize perfusion defects. After the injection of regadenoson, hemodynamic parameters and potential side-effects were closely monitored. Side-effects were stratified per severity as mild, moderate and severe. Studies were read by nuclear medicine physicians using quantitative perfusion SPECT software. Additional diagnostic information such as wall motion and wall thickening were provided by gating. Results: Thirty-three patients (66%) experienced one or more side-effects upon the administration of regadenoson, most commonly warmth and chest discomfort. In all patients but one (98%), the symptoms were mild, of short duration and self-limiting. Out of all side-effects registered, 44 (96%) were mild, and 2 (4%) were moderate. Two moderate side-effects developed in one patient with a prior history of asthma, and included shortness of breath and cough. Heart rate changed by 16 +- 31 bpm. Highest increase in blood pressure was 30 mm Hg for systolic, and 10 mm Hg for diastolic. One case of significant decrease in blood pressure was noted from the hypertensive basal values, 50 mm for systolic, and 30 mm Hg for diastolic. ST segment depression of up to 1 mm occurred in 4 cases (8%), and T-wave changes in 3 cases (6%). No conduction abnormalities, significant hypotension, symptomatic bradycardia or cardiac arrest ocurred. Conclusion: Our first institutional experiences proved regadenoson as A2A selective adenosine agonist as a pharmacologic stressor to be safe, tolerable and easily used. Its safety profile enabled the study to be performed in patients with respiratory disease also.

Kako će digitalizirana građa biti dostupna što većem broju ljudi? Koju tehnologiju upotrebljavamo za to? Da li je dostupna svima? Šta je LoCloud i kako funkcionira? U radu će se objasniti primjena tehnologije kojom se kreiraju digitalne biblioteke, muzeji i arhivi. Za primjer LoCloud kolekcija uzet će se digitalne kolekcije nastale u Nacionalnoj i univerzitetskoj biblioteci BiH putem LoCloud i CSEEE projekata. = How will be digitized material accessible to as many people as possible? What technology is used for this? Is it available to everyone? What is LoCloud and how does it work? This paper will explain use of technology to create digital libraries, museums and archives. For LoCloud collection example we will use digital collections created in the National and University Library of Bosnia and Herzegovina through LoCloud and CSEE projects.

Šta se dešava nakon digitalizacije građe, obrade digitalizovanog materijala, tačnije ocerovanja2? Kako se digi-talizovana serijska publikacija katalogizuje? Da li joj se dodjeljuje ISSN? Cilj rada je da objasni pravila dodjele ISSN broja digitalizovanoj građi, ko je može dobiti, te koja se polja dodaju zapisima digitalizovane građe u ISSN kataloškom programu (Virtua Integrated Library System). U radu će se dati primjeri digitalizovanih serijskih pu-blikacija kojima su dodijeljeni ISSN brojevi. = What happens after digitization, processing of digitized material, namely OCR? How is the digitized serial cata-loged? Is the ISSN assigned to it? The aim of the article is to explain ISSN assignement rules to the digitized ma-terials, who can get it, and which fields are added to the records of digitized material in ISSN cataloging program (Virtua Integrated Library System). This paper will give examples of digitized serials to which ISSN numbers are assigned.

UDK: 630*52/*56:519.8(497.6) The aim of this research was to evaluate estimates of the current annual increment of volume (CAIv) variability considering growing stock (V) as structural variable and topographic conditions and Landsat 8 spectral response as environmental variables on hilly and mountainous mixed forests in the northeast Bosnia using multiple linear regressions based on ordinary least squares (MLR) and geographically weighted regression (GWR). Sample data contains geo-referenced forest inventory data, CAIv (m3/ha/year) and V (m3/ha), extracted values from digital terrain model (altitude, slope and aspect) and derived principal components values from Landsat 8 satellite image for forest stands of the management unit located on hilly and mountain positions in protected area Konjuh, Kladanj. Here are applied MLR and GWR using stepwise procedure. MLR and GWR analyses resulted with global coefficients of significant predictors on hilly position. This was expected due to homogenous vegetation and environmental conditions on hilly position. It was found that growing stock affected CAIv the most. Significant improvement of regression modeling is achieved by GWR appliance on sample from mountainous position. There were obtained local influence of growing stock and the first principle component related to green biomass on CAIv. The highest improvement is found for broadleaves CAIv where quantification of local variability of growing stock increased adjusted coefficient of determination about 11% and reduced relative root mean square error for 6%. Local character of green biomass related to conifers CAIv did not improve regression estimation significantly. The broadleaves root mean square error based on GWR was 1.60 m3/ha/year (coefficient of variation more than 30%) which is still high so further modeling including other structural characteristics (stems number, basal area, mixture) as predictors is required. 

Introduction: Aging, as an irrepressible biological process involves a series of physiological and pathological changes. The main aim of this study was to examine the correlation and predictability of receptive vocabulary and cognitive functioning of elderly people with anamnestic variables: chronological age, sex, level of formal education, marital status, years of work and retirement and years spent in an institution for the elderly. Material and Methods: The sample of participants consisted of 120 elderly people, average age was 78 years, placed in institutional care for elderly people in four cities in Bosnia and Herzegovina. It was three groups of variables: anamnestic, receptive vocabulary assessment, and cognitive assessments. A Montreal Cognitive Assessment Scale (MoCA) was used for the assessment of cognitive abilities. In order to estimate the receptive vocabulary Peabody Picture Vocabulary Test (PPVT-III-HR) was used. Results: Results of multiple regression analysis show that part of the variance of receptive language which is explained by the model (anamnestic variables) was 44.0% and of cognitive functioning was 33.7%. The biggest single contribution to explaining the development of receptive vocabulary was given by predictor variable of college education (β = 0.417) then variable university education (β = 0.293), while the smallest single contribution was given by variable secondary education (β = 0.167). The biggest single contribution to explaining the results of tests of cognitive function was given by predictor variable College education (β = 0.328) and variable unskilled (β = -0.229), which has a negative effect on the increase in recent cognitive functioning. Conclusion: Anamnestic variables were valid predictors of receptive vocabulary and cognitive functioning of elderly people. The highest individual contribution was given by variables describing the level of formal education of elderly.

Introduction: Anemia in preterm infants is the pathophysiological process with greater and more rapid decline in hemoglobin compared to the physiological anemia in infants. There is a need for transfusions and administration of human recombinant erythropoietin. Aim: To determine the frequency of anemia in premature infants at the Pediatric Clinic, University Clinical Center Sarajevo, as well as parameter values in the blood count of premature infants and to explore a relationship between blood transfusions with the advent of intraventricular hemorrhage (determine treatment outcome in preterm infants). Patients and methods: Research is retrospective study and it included the period of six months in year 2014. Research included 100 patients, gestational age < 37 weeks (premature infants). Data were collected by examining the medical records of patients at the Pediatric Clinic, UCCS. Results: The first group of patients were premature infants of gestational age ≤ 32 weeks (62/100) and the second group were premature infants of gestational age 33-37 weeks (38/100). Among the patients, 5% were boys and 46% girls. There was significant difference in birth weight and APGAR score among the groups. In the first group, there were 27.42% of deaths, while in the second group, there were only 10.53% of deaths. There was a significant difference in the length of treatment. There was a statistically significant difference in the need for transfusion among the groups. 18 patients in the first group required a transfusion, while in the second group only 3 patients. Conclusions: Preterm infants of gestational age ≤ 32 weeks are likely candidates for blood transfusion during treatment. Preterm infants of gestational age ≤ 32 weeks have the risk of intracranial bleeding associated with the application of blood transfusion in the first week of life.

UDK: 595.768.1:582.475(234.422 Zvijezda) Bark beetles are the most important pests of the coniferous forests. Although they are considered to be a secondary pest, they are becoming the primary pests that attack healthy trees. One of the important spruce bark beetle is the Pityogenes chalcographus (L.) - a small spruce beetle. The research was conducted in the municipality of Vareš, on three locations: Ponikva, Pobrin Han, Doli. The active period of the bark beetle for development began in the last decade of April. P. chalcographus in the field of research had two generations. For the development of generations it took between 12 and 13 weeks. Weather conditions in the object of research did not allow the completion of the second generation. The activity of the bark beetle ends in mid-September. When we talk about the characteristics of wood material which prefers small bark beetle of spruce, we can say that he prefers to inhabit thinner parts of trunk with thin and smooth rind. In the object of research for monitoring of population of bark beetle P. chalcographus was used trap trees. As a measure to combat the small spruce bark beetles are strongly advised in due time, autumn and winter, remove the dried trees and trees with drilled bark beetles. Maintenance and establishment of forest order to reduce the amount of wood material suitable for the settlement of bark beetles.

Introduction: Parkinson’s disease (PD) is chronic progressive neurodegenerative disease. In patients with Parkinson’s disease among other symptoms occur cognitive dysfunctions, which can be shown by P300 wave changes. Aim: The aim of this study was to demonstrate that patients with Parkinson’s disease have reduced amplitude and prolonged latency, longer than 300 ± 10 ms. Material and Methods: The study included 21 patient suffering from Parkinson’s disease. After reviewing the medical records and analyzes the inclusion and exclusion criteria, patients were subjected to the same procedure examining auditory cognitive potentials (P300 wave) and the results were analyzed and compared to reference value for healthy population. Results: We have shown that patients with Parkinson’s disease have prolonged P300 targeted and frequent stimulus latency compared to reference value for healthy population. From 21 patient 18 had a pathological P300 target stimulus amplitude, and even 20 patients had pathological P300 frequent stimulus amplitude. Conclusion: People with Parkinson’s disease have altered P300 which indicates the presence of cognitive dysfunction in these patients.

Abstract The paper explores the existence of cognitive linguistics principles in translation of emotion-related metaphorical expressions. Cognitive linguists (Lakoff & Johnson, 1980; Lakoff, 1987) define metaphor as a mechanism used for understanding one conceptual domain, target domain, in terms of another conceptual domain, source domain, through sets of correspondences between these two domains. They also claim that metaphor is omnipresent in ordinary discourse. Cognitive linguists, however, also realized that certain metaphors can be recognized and identified in different languages and cultures whereas some are language- and culture-specific. This paper focuses on similarities and variations in metaphors which have recently become popular within the discipline of Translation Studies. Transferring and translating metaphors from one language to another can represent a challenge for translators due to a multi-faceted process of translation including both linguistic and non-linguistic elements. A number of methods and procedures have been developed to overcome potential difficulties in translating metaphorical expressions, with the most frequent ones being substitution, paraphrase, or deletion. The analysis shows the transformation of metaphorical expressions from one language into another and the procedures involving underlying conceptual metaphors, native speaker competence, and the influence of the source language.

Изет Машич1, 2,*, Един Бегич3, 4, Дончо M. Донев5, Сречко Гайович6, Армен Ю. Гаспарян7, Миро Яковлевич8, Деян Б. Милошевич9, 10, Осман Синанович2, 11, Шекиб Соколович12, Сельма Узунович13, Энвер Зерем14, 15 1Медицинский факультет, Университет Сараево, Сараево, Босния и Герцеговина 2Академия медицинских наук Боснии и Герцеговины, Сараево, Босния и Герцеговина; https://orcid.org/0000-00029080-5456 3Медицинский факультет, Школа науки и технологий Сараево, Сараево, Босния и Герцеговина 4Центр охраны здоровья, Маглай, Босния и Герцеговина; http://orcid. org/0000-0001-6842-262X 5Институт социальной медицины, медицинский факультет, Университет им. св. Кирилла и Мефодия в Скопье, Скопье, Республика Македония; https://orcid.org/0000-0002-5237-443X 6Хорватский институт исследований мозга, Школа медицины при Загребском университете, Загреб, Хорватия; http://orcid.org/0000-0001-86685239 7 Отделение ревматологии и отдел исследований и развития, Дадли группа Благотворительного фонда Системы общественного здравоохранения (Образовательный фонд Университета Бирмингема, Великобритания), Расселовский Ходл Госпиталь, Дадли, Уэст-Мидлендс, Великобритания; https://orcid.org/0000-0001-8749-6018 a.gasparyan@gmail.com 8Отделение психиатрии, Центральная университетская клиника Загреба, Загреб, Хорватия 9Факультет естественных наук, Университет Сараево, Сараево, Босния и Герцеговина 10Aкадемия наук и художеств Боснии и Герцеговины, Сараево, Босния и Герцеговина; http://orcid.org/0000-00015060-3318 11Отделение неврологии, Университетский клиническй центр Тузлы, медицинский факультет, Университет Тузлы, Тузла, Босния и Герцеговина; http://orcid.org/0000-0001-8957-7284 12Институт болезней сердца, Университетский клинический центр Сараево, Сараево, Босния и Герцеговина; http://orcid.org/0000-00016321-4186 13Отделение лабораторной диагностики, Институт общественного здоровья и продовольственной безопасности, Зеница, Босния и Герцеговина; http:// www.orcid.org/0000-00031852-1572 14Отделение медицинских наук, Академия наук и художеств, Сараево, Босния и Герцеговина 15Отделение гастроэнтерологии и гепатологии, Университетский клинический центр Тузлы, Тузла, Босния и Герцеговина; http://orcid. org/0000-0001-6906-3630