Episiotomy is obstetric procedure during which the incision extends the vestibule of the vagina during the second stage of labor. Episiotomy was extensively spread with gradual increase of rates in the first half of the 20th century and was performed medio-laterally in all nulliparous women with the idea to protect fetal head from trauma and pelvic floor from injuries. However, reports claiming that episiotomy had no such benefits were published. It was shown that routine medio-lateral episiotomy did not protect against the appearance of urinary incontinence after vaginal delivery, while the risk of anal incontinence could be increased. The role of episiotomy in development of pelvic floor dysfunction remains quite unclear. Due to the mentioned reason, restricted episiotomy approach should be accepted. The origin of stress incontinence during pregnancy is controversial and not definitely scientifically proven. Pregnancy per se and older age at first delivery may have impact on the onset of pelvic floor dysfunction. Urinary incontinence in pregnancy increases the risk of later urinary incontinence, both postpartum and later in life. Vaginal delivery is just one of the potential risk factors for development of urinary incontinence. Mechanical pressure by fetus on the pelvic floor structures, limited denervation of the pelvic floor and soft tissue damage during delivery are some of explanations for the onset of stress urinary incontinence. On the other hand, cesarean delivery might not be protective against emergence of urinary incontinence. Further research in this field is needed.

This paper deals with teaching management of different learning styles students use in the EFL classroom. It explores various types of learning styles and it provides directions that can help EFL teachers in better understanding of various learning preferences and in responding to different types of learners. Different types of learners are also treated in this paper. In addition to theoretical explanations for every type of learner mentioned, different methods and approaches are incorporated, together with suggestions for activities suitable for particular learners. The last part of the paper is a study of Bosnian teenagers’ learning styles and their implication in teaching. The aim of the study was to investigate major learning styles of Sarajevo teenagers and how they affect their learning. The results and analysis of the study are presented at the end of this paper.

Importance Epigenetic modifications of the genome, such as DNA methylation and histone modifications, have been reported to play a role in neurodegenerative diseases (ND) such as Alzheimer’s disease (AD) and Parkinson’s disease (PD). Objective To systematically review studies investigating epigenetic marks in AD or PD. Methods Eleven bibliographic databases (Embase.com, Medline (Ovid), Web-of-Science, Scopus, PubMed, Cinahl (EBSCOhost), Cochrane Central, ProQuest, Lilacs, Scielo and Google Scholar) were searched until July 11th 2016 to identify relevant articles. We included all randomized controlled trials, cohort, case-control and cross-sectional studies in humans that examined associations between epigenetic marks and ND. Two independent reviewers, with a third reviewer available for disagreements, performed the abstract and full text selection. Data was extracted using a pre-designed data collection form. Results Of 6,927 searched references, 73 unique case-control studies met our inclusion criteria. Overall, 11,453 individuals were included in this systematic review (2,640 AD and 2,368 PD outcomes). There was no consistent association between global DNA methylation pattern and any ND. Studies reported epigenetic regulation of 31 genes (including cell communication, apoptosis, and neurogenesis genes in blood and brain tissue) in relation to AD and PD. Methylation at the BDNF, SORBS3 and APP genes in AD were the most consistently reported associations. Methylation of α-synuclein gene (SNCA) was also found to be associated with PD. Seven studies reported histone protein alterations in AD and PD. Conclusion Many studies have investigated epigenetics and ND. Further research should include larger cohort or longitudinal studies, in order to identify clinically significant epigenetic changes. Identifying relevant epigenetic changes could lead to interventional strategies in ND.

The purpose of this study was to assess the most frequent non-conformities identified in different European countries in the processes of forest management certification according to FSC standards. A total of 31 active certificates from five countries (Bosnia and Herzegovina, Estonia, Romania, Slovenia and the United Kingdom) were analysed, including all active certificates (as of 1st of June 2014) from three countries along with a sample of 13 FSC certificates issued in the UK and one certificate covering 95% of the certified forest area in Slovenia. 253 non-conformities in relation to FSC standard requirements were identified as formulated by the audit teams and the most frequently identified non-conformities in the certification process were those related to Principle 6 - Environmental impact (34%), Principle 4 - Community relations and worker’s rights (17%) and Principle 8 - Monitoring and Assessment (13%). A slight positive correlation was noticed between the FSC certified area and the total number of non-conformities, with a closer link in the case of Principle 9 - Maintenance of high conservation value forests, and Principle 4. The non-conformities related to Principles 4, 6 and 9 appeared to be significantly influenced in occurrence by country development; less often in the UK compared with the other four countries.

This paper presents a systematic but essentially descriptive account of the policy measure of stimulating human research capacity development under the policy program “Commitment to Science” in Portugal in the period 2006-2009. It explores the conditions that contributed to the development of the policy program and the measure to contract 1000 doctorates to Portuguese public and private research and development (RD however subsequent economic and political austerity hampered the absorption of young researchers into the public and private systems. The previous situation has been reversed since 2011 with a significant and perceivable decline in public investment in research, a decline of budgetary allocations to universities, and the migration of young researchers abroad. The analysis urges the revision of science and technology policy in Portugal and funding mechanisms available to R&D in consideration of the country’s socioeconomic situation, and with respect to other segments of the economic ecosystem.