The application of information technology in all areas represents a significant facilitation of all business processes and activities. A competitive business system is hardly imaginable without adequate information technology. Therefore, this paper evaluates the conditions for the implementation of barcode technology in a warehouse system of a company for the manufacture of brown paper. SWOT (Strengths, Weaknesses, Opportunities, Threats) matrix was formed with a total of 27 elements based on which the benefits of the implementation of barcode technology in the warehouse system need to be analysed. For this purpose, a new fuzzy PIPRECIA (PIvot Pairwise RElative Criteria Importance Assessment) method has been developed to evaluate all elements in SWOT matrix. In addition, a part of the new developed approach includes new fuzzy scales for criterion assessment that are adapted to the methodology required by the fuzzy PIPRECIA method. To determine the consistency of the method, Spearman and Pearson correlation coefficients are applied. The results obtained in this study show that weaknesses are most noticeable in the current system. By implementing barcode technology, it is possible to create opportunities defined in SWOT matrix, which, in a very efficient way, allow elimination of the current weaknesses of the system.

Clinical Center University of Sarajevo, Sarajevo, Bosnia and Herzegovina KeYWORdS: carotid artery stenosis, peak-systolic velocity, multiple risk factors. citAtiON: Cardiol Croat. 2018;13(11-12):443. | https://doi.org/10.15836/ccar2018.443 *AddReSS fOR cORReSpONdeNce: Amina Bičo, Clinic of Heart and Blood Vessel Diseases, Clinical Center University of Sarajevo, Bolnička 25, 71000 Sarajevo, Bosnia and Herzegovina. / Phone: +387-61-348-688 / Email: amina.osmanagic@yahoo.com ORcid: Amina Bičo, https://orcid.org/0000-0001-6937-1772 • Alden Begić, https://orcid.org/0000-0002-5374-0892 Dževdet Radončić, https://orcid.org/0000-0001-5917-2956 • Mirza Dilić, https://orcid.org/0000-0002-7309-1455

Studying the behavior of social insect using computer vision algorithms is an interesting topic for both biological and signal processing communities. One of the most interesting aspects in the field is tracking of honeybees. Regarding computer vision method, honeybees’ behavior has been mostly monitored inside and at the entrance of the hive. In this research we are proposing the method for automatic monitoring of honeybees’ activity outside of the hive. Experiments showed that the activity of honeybees outside the hive can estimated using an ultra-high definition video captured with UAV from distance of 10 meters. Specific spots where honeybees are gathered can be detected using heat maps which represent the density of their occurrence in the observed time interval.

This paper investigates the importance of different parameters of split-brain autoencoder to performance of learned image representations for remote sensing scene classification. We investigate the usage of LAB color space as well as color space created using PCA applied to RGB pixel values. We show that these two spaces give almost equal results, with slight favor towards the LAB color space. We also investigate choices of different quantization methods of color targets and number of quantization bins. We have found that using k-means clustering for quantization works slightly better than using uniform quantization. We also show that even when using really small number of bins it is possible to get only slightly worse results.

Phthalate esters are suspected endocrine disruptors that are found in a wide range of applications. The aim of this study was to determine the excretion of urinary metabolites in 16 individuals after inhalation and/or dermal exposure to 100–300 µg/m3 of deuterium-labelled diethyl phthalate (D4-DEP) and bis(2-ethylhexyl) phthalate (D4-DEHP). Dermal exposure in this study represents a case with clean clothing acting as a barrier. After inhalation, D4-DEP and D4-DEHP metabolites were excreted rapidly, though inter-individual variation was high. D4-DEP excretion peaked 3.3 h (T½ of 2.1 h) after combined inhalation and dermal exposure, with total excreted metabolite levels ranging from 0.055 to 2.351 nmol/nmol/m3 (nmol of urinary metabolites per phthalates air concentration in (nmol/m3)). After dermal exposure to D4-DEP, metabolite excretion peaked 4.6 h (T½ of 2.7 h) after exposure, with excreted metabolite levels in between 0.017 and 0.223 nmol/nmol/m3. After combined inhalation and dermal exposure to D4-DEHP, the excretion of all five analysed metabolites peaked after 4.7 h on average (T½ of 4.8 h), and metabolite levels ranged from 0.072 to 1.105 nmol/nmol/m3 between participants. No dermal uptake of particle phase D4-DEHP was observed. In conclusion, the average excreted levels of metabolites after combined inhalation and dermal exposure to D4-DEP was three times higher than after combined exposure to D4-DEHP; and nine times higher than after dermal exposure of D4-DEP. This study was made possible due to the use of novel approaches, i.e., the use of labelled phthalate esters to avoid the background concentration, and innovative technique of phthalate generation, both in the particle and the gas phase.

Rheumatoid arthritis (RA) is an inflammatory joint disease that eventually leads to permanent bone and cartilage destruction. Fas has already been established as the regulator of inflammation in RA, but its role in bone formation under arthritic conditions is not completely defined. The aim of this study was to assess the effect of Fas inactivation on the bone damage during murine antigen‐induced arthritis. Subchondral bone of wild‐type (WT) and Fas‐knockout (Fas−/−) mice was evaluated by histomorphometry and microcomputerized tomography. Proportions of synovial bone and cartilage progenitors were assessed by flow cytometry. Synovial bone and cartilage progenitors were purified by fluorescence‐activated cell sorting and expression of Fas and Fas‐induced apoptosis were analyzed in vitro. Results showed that Fas−/− mice developed attenuated arthritis characterized by preserved epiphyseal bone and cartilage. A proportion of the earliest CD200+ bone and cartilage progenitors was reduced in WT mice with arthritis and was unaltered in Fas−/− mice. During osteoblastic differentiation in vitro, CD200+ cells express the highest levels of Fas and are removed by Fas ligation. These results suggest that Fas‐induced apoptosis of early CD200+ osteoprogenitor population represents potential mechanism underlying the impaired bone formation in arthritis, so their preservation may represent the bone‐protective mechanism during arthritis.—Lazić Mosler, E., Lukač, N., Flegar, D., Fadljević, M., Radanović, I., Cvija, H., Kelava, T., Ivčević, S., Šućur, A., Markotić, A., Katavić, V., Marušić, A., Grčević, D., Kovačić, N. Fas receptor induces apoptosis of synovial bone and cartilage progenitor populations and promotes bone loss in antigen‐induced arthritis. FASEB J. 33, 3330–3342 (2019). www.fasebj.org

This paper describes the preparation and application of “home-made” iodide ISE enriched with ZnO nanoparticles. Iodide ISE membrane was made of AgI:Ag 2 S:PTFE = 1:1:2 and enriched with ZnO nanoparticles in ratio 1-5.0 wt.%. Prepared membranes were used for penicillamine (Pen) determination in acetic buffer (pH = 4-4.75) and in perchloric acid (pH = 1-2). Due to the low price method, simplicity and relative speed, a possibility for Pen determination was found. Pen determination showed better results in an acetic buffer, pH = 4 than in perchloric acid. All experiments for Pen measurements were done without pretreatment of pharmaceuticals. The determination is based on the reaction between Pen with both Ag + and Zn 2+ from the electrode membrane. A newly described method has linear response range for Pen 2.45×10 −6 -1×10 −2 mol L −1 and a detection limit of 2.24×10 −6 mol L −1 . The found concentrations of Pen are in a very good agreement with the declared ones with the standard deviation of 2.70 %.

Introduction: Schizophrenia(SCZ) and Bipolar disorder (BD) are frequently occurring and impairing disorders that affect around 1% of the population. Important endophenotypes in the genetic research of SCZ and BD are cognitive functions. Core symptoms for SCZ and BD are impairments in working memory, declarative memory and attention, all of which fulfill the criteria for an endophenotype. The FK506 Binding Protein 5 (FKBP5) gene codes for a co-chaperone of the glucocorticoid receptor and has been reported to be associated with cognition. Aim: The aims of our research were to determine the degree of cognitive impairment in patients suffering from SCZ and BD and to explore the association of the FKBP5 variant rs3800373 genotype with the cognitive endophenotypes. Material and Methods: Patients and healthy controls were recruited over a period of two years from the Psychiatric Clinic, Clinical Center University of Sarajevo. Genotyping and neuropsychological assessments were performed for 263 subjects (129 SCZ, 53 BD, and 81 healthy controls [HC]). Neuropsychological assessments were performed for all patients with the Trail Making Test-A&B (TMT-A&B) and Digit-span forward&backwards tasks. The single nucleotide polymorphism (SNP) rs3800373 in the FKBP5 gene was genotyped using Infinium PsychArray Bead Chips. Results and Conclusion: SCZ and BD patients performed lower than HC in the TMT-A&B and in the Digit-span backwards task, while no differences were observed between SCZ and BD patients. While SCZ patients performed lower than HC in the Digit-span forwards task, there were no differences between BD and HC or between BD and SCZ. Rs 3800373 was not associated with performance in the TMT-A&B or Digit-span forwards&backwards tasks. SCZ and BD share largely overlapping neurocognitive characteristics. Rs3800373 was not associated with performance in the neuropsychological tests. However, given the limited sample size, the results do not exclude an association with the rs3800373 variant in a larger sample. Furthermore, as the analysis was limited to one SNP, the results cannot be generalized to other genetic variants in FKBP5.