Genetic structure of two human populations, indigenous and migratory population in the area of the Tuzla region, was analyzed with respect to some static and dynamic-morphological properties. The analyzed genetic data were collected by direct observation and survey of 472 pupils of school age. The investigated parameters of genetic heterogeneity were estimated by: analysis of the frequency of recessive phenotypes for every observed property, t-test analysis, and assessment of intragroup variation by analysis of Wahlund variance. Based on the obtained results it was observed that the frequency of the recessive homozygote for most of the analyzed properties was slightly higher in migratory populations. All values obtained by Wahlund variance analysis indicated a small genetic differentiation.

The impact of certain exogenous factor (socio-economic, ecological) has been investigated with special attention paid to the parents' living standard, and number of family members on some anthropometric parameters like: body height, body mass, chest circumference, upper leg circumference, upper arm circumference, sitting height, arm length, leg length, pelvis width, shoulders width, lenght of head and with of head on the sample of 698 boys aged 11 to 16 (17) years in the Tuzla region (the northeastern Bosnia, Western Balkan peninsula). Anthropometric measurements have been carried out using methodology proposed by the International Biological program (IBP). The results of these investigations have shown that there is a certain impact of the socio-economic conditions on the growth and development of boys. Children from families that have better living standard are, as a rule, taller, which is indicated by the statistical significant differences (P > 0.01). This trend indicates also value of Body Mass Index (BMI), which is in younger children from the families with lower living standard 16, while in the same category in the children from the families with better living standard it has value 18.5. The real impact of living conditions on the dynamics of development could be the best seen in the period of puberty. The number of children in the family has negative relationship with anthropometric features. Statistically significant differences (P > 0.001) have been detected in numerous analysed features in families with one or two children in comparison with families with three, four, or five children. Therefore, BMI has been significantly lower (16) in children from families with several children, while in the families with one child in the same growth class (11 years) it was significantly higher (17.4). Similar value of BMI (17.9) have children from the families with five children and which are 17 years old. Besides socio-economic conditions, high level of environmental pollution which is typical for Tuzla region for a long time, has also significant impact on the growth and development of children.

Within 16 year-period secular trend in seven measurements of physical growth of male children and youth from Tuzla Region, was researched by corresponding analysis of the sample that involved 1329 researched subjects. Our data were compared with the results of research from 1980 in the sample of 1349 boys. Nine successive generations in 1980 and 1996, from Tuzla region, were involved in this research. Analysis of the data obtained is based primarily on scientific elaboration of the situation registered in 1996 in the tested part of the broader population, after an unnatural and extremely unfavorable period for physical growth of the large majority of that population. The aim of this research was to establish secular trend (negative or positive) for the seven measurements of physical growth of male children and youth comparing our results from 1996 to corresponding research results on growth and development from1980, the sample of about same population (nearly same number of investigated persons). Although the unfavorable war living conditions negatively affected ontogenesis of the researched subjects, body dimensions of male children and youth were established as harmonious, in the limits of average European standards. However, it seems the unfavorable living conditions caused temporary slowdown in body dimensions, so, for these generations (11 to 19 years old), we could not find any increase of mean values (for certain number) of the researched parameters in comparison with the sample from 1980 year. So, 16 year-acceleration trend for most parameters was established and it is particularly evident inpost pubertal period.