The purpose of this study has been evaluation our possibilities of diagnostic and treatment children with congenital heart disease. We were analyzing medical documentation from 352 children with discovered congenital heart disease in period of six years in Tuzla Canton area. disease. The average age at diagnosis was 2,15±2,28 years. During first cardiac examination 51,98% children presented symptoms of cardiac disease. Growth retardation in postnatal period is noticed in 13,35%. Electrocardiographic changes are registered in 47,76%, while changed chest radiogram in 53,85% of patients. Medicament treatment was needed in 20,74% and cardiovascular surgery procedure in 40,60%. Urgent surgery treatment was needed in 62 patients with critical heart disease. Cardiovascular surgery was made in 23,29% of patients, and average age was 4,81±3,23 years. Mortality of children with congenital heart disease is relatively high and it is 19,60%, the biggest number of them (95,65%) died before and only 4,35% after cardiosurgical treatment. Average age of children who died was 0,51±0,59 year. Considering clinical indicators of congenital heart disease in Tuzla Canton area, it is evidenced that this children health problem, which due difficult clinical picture, big involvement in infant mortality, growth retardation with progression in chronic cardiopathy, require urgent measures with main goal on advanced organizing of its diagnostic and treatment.

Cilj rada je analiza rezultata neonatalnog TSH skrininga na kongenitalni hipotireoidizam u funkciji procjene jodnog deficita i stepena težine javno zdravstvenog problema koji proizilazi iz njegovog postojanja. Distribucija neonatalnog TSH pokazuje da je od ukupnog broja ispitivane novorođenčadi 11.7% imalo veće, a 88.3% manje vrijednosti TSH od 5 mU/L. Pokazalo se da rezultati neonatalnog TSH i urinarne ekskrecije joda u svim opštinama Tuzlanskog kantona ukazuju na prisustvo blagog, dok rezultati prevalencije gušavosti u šest opština ukazuju na blag, u pet na umjeren i u dvije na težak stepen jodnog deficita. Naši rezultati potvrđuju da je neonatalni TSH skrining na kongenitalni hipotireoidizam koristan, praktičan i senzitivan biološki pokazatelj jodnog deficita i da daje mogućosti kontinuiranog praćenja efikasnosti jodne suplementacije. Mi sugerišemo implementaciju ovog skrininga u funkciji oba pokazatelja (otkrivanje sporadičnog permanentnog hipotireoidizma i procjena stepena jodnog deficita) na području cijele Bosne i Hercegovine. Pored navedenog, dobijeni rezultati su pokazali da na području Tuzlanskog kantona i dalje egzistira blag stepen jodnog deficita, odnosno daje tekuća jodna profilaksa neadekvatna, tj. daje sadržaj joda u soli nezadovoljavajući.