Aim To compare morphologic variations of occipital sulci patterns in patients with schizophrenia and migraine headache regarding gender and laterality using magnetic resonance imaging (MRI) and visual evoked potentials (VEPs) as well as damage of visual pathway in patients with schizophrenia. Methods This study included 80 patients. Brain scans and visual evoked potential responses recorded over the occipital cortex were performed to analyze the occipital region of both hemispheres. Average total volumes of both hemispheres and average values of latency of the healthy population were used for comparison. Results There was statistically significant difference between subjects considering gender (p=0.012). Parameters of body of the calcarine sulcus (p=0.0325) showed statistically significant positive correlation with P100 latency (p=0.0449), inferior sagittal sulcus (p=0.0443) had significant positive correlation with P100 latency (p=0,0413), lateral occipital sulcus (p=0.0411) and P100 latency (p=0.0321) showed statistically significant difference only of left hemisphere in male patients with schizophrenia with shallower depth of the sulcus and P100 latency prolongation. Conclusion The consistency of the findings reveals distinct multiple brain regions, which show changes in the gray matter of patients with chronic forms of schizophrenia. The neurocognitive deficits of schizophrenia show highly consistent cross-sectional relationships to each type of functional outcome.

Aim To examine the presence of morphologic variations of occipital sulci patternsin patients with schizophrenia and migraine headacheregarding gender and laterality using magnetic resonance imaging (MRI). Methods This study included 80 patients and brain scans were performed to analyze interhemispheric symmetry and the sulcal patterns of the occipital region of both hemispheres. Average total volumes of both hemispheres of the healthy population were used for comparison. Results There was statistically significant difference between subjects considering gender (p=0.012)with no difference regarding age(p=0.1821). Parameters of parieto-occipital fissure (p=0.0314), body of the calcarine sulcus (p=0.0213), inferior sagittal sulcus (p=0.0443), and lateral occipital sulcus (p=0.0411) showed statistically significant difference only of left hemisphere in male patients with schizophrenia with shallowerdepth of the sulcus. Conclusion Representation of neuroanatomical structures suggests the existence of structural neuroanatomic disorders with focal brain changes. Comparative analysis of occipital lobe and their morphologic structures (cortical dysmorphology) in patients with schizophreniausing MRI, according to genderindicates a significant cortical reduction in the left hemisphere only in the group of male patients compared to female patients and the control group.